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I. Hauber · SciRah

Researcher profile · Semantic Scholar

I. Hauber

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I. Hauber — researcher profile on SciRah

h-index: 27
Works: 50
Citations: 2,473

Most-cited papers

HIV-1 Proviral DNA Excision Using an Evolved Recombinase
I. Sarkar, I. Hauber, J. Hauber, F. Buchholz
2007Science216 citations
Semantic Scholar
Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses
T. Efferth, M. Marschall, Xin Wang, S. Huong +5 more
2002Journal of molecular medicine178 citations
Semantic Scholar
Kit regulates HSC engraftment across the human-mouse species barrier.
K. Cosgun, Susann Rahmig, N. Mende, Sören Reinke +14 more
2014Cell Stem Cell167 citations Open access
Semantic Scholar
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection
I. Hauber, H. Hohenberg, B. Holstermann, W. Hunstein +1 more
2009Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation
B. Jensen, E. Knops, Leon Cords, N. Lübke +32 more
2023Nature Medicine141 citations Open access
Semantic Scholar
mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5
Ulrike Mock, Rafał Machowicz, I. Hauber, S. Horn +4 more
2015Nucleic Acids Research131 citations Open access
Semantic Scholar
Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity
J. Karpinski, I. Hauber, J. Chemnitz, Carola Schäfer +16 more
2016Nature Biotechnology123 citations
Semantic Scholar
A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency.
M. B. Fischer, I. Hauber, H. Eggenbauer, V. Thon +6 more
1994Blood102 citations Open access
Semantic Scholar
Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy.
I. Hauber, D. Bevec, J. Heukeshoven, Friedrich Krätzer +4 more
2005Journal of Clinical Investigation99 citations Open access
Semantic Scholar
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach.
S. Balabanov, Artur Gontarewicz, Patrick Ziegler, U. Hartmann +13 more
2007Blood97 citations Open access
Semantic Scholar
Anti‐inflammatory properties of human serum IgA: induction of IL‐1 receptor antagonist and FcαR (CD89)‐mediated down‐regulation of tumour necrosis factor‐alpha (TNF‐α) and IL‐6 in human monocytes
H. M. Wolf, I. Hauber, H. Gulle, A. Samstag +3 more
199679 citations Open access
Semantic Scholar
The strength of the HIV-1 3' splice sites affects Rev function
Susanne Kammler, M. Otte, I. Hauber, J. Kjems +2 more
2006Retrovirology75 citations Open access
Semantic Scholar
Highly Significant Antiviral Activity of HIV-1 LTR-Specific Tre-Recombinase in Humanized Mice
I. Hauber, H. Hofmann-Sieber, J. Chemnitz, D. Dubrau +14 more
2013PLoS Pathogens70 citations Open access
Semantic Scholar
Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases
Ulrike Mock, I. Hauber, B. Fehse
2016Nature Protocols63 citations
Semantic Scholar
Analysis of Nucleocytoplasmic Trafficking of the HuR Ligand APRIL and Its Influence on CD83 Expression*
Barbara Fries, J. Heukeshoven, I. Hauber, C. Grüttner +4 more
2007Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues.
Tristan Gollnest, Thiago Dinis de Oliveira, Anna K. Rath, I. Hauber +3 more
2016Angewandte Chemie60 citations
Semantic Scholar
Defective integration of activating signals derived from the T cell receptor (TCR) and costimulatory molecules in both CD4+ and CD8+ T lymphocytes of common variable immunodeficiency (CVID) patients
V. Thon, H. Wolf, M. Sasgary, J. Litzman +4 more
1997Clinical and Experimental Immunology58 citations Open access
Semantic Scholar
Defective interleukin-2 and interferon-gamma gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency.
M. B. Fischer, I. Hauber, E. Vogel, H. Wolf +2 more
1993Journal of Allergy and Clinical Immunology56 citations
Semantic Scholar
Activation via the antigen receptor is impaired in T cells, but not in B cells from patients with common variable immunodeficiency
M. B. Fischer, H. Wolf, I. Hauber, H. Eggenbauer +3 more
1996European Journal of Immunology54 citations
Semantic Scholar
A minimal uORF within the HIV-1 vpu leader allows efficient translation initiation at the downstream env AUG.
Jörg Krummheuer, A. Johnson, I. Hauber, Susanne Kammler +4 more
2007Virology51 citations Open access
Semantic Scholar
Assessment of the range of the HIV-1 infectivity enhancing effect of individual human semen specimen and the range of inhibition by EGCG
P. Hartjen, S. Frerk, I. Hauber, V. Matzat +6 more
2012AIDS Research and Therapy48 citations Open access
Semantic Scholar
Insights into the selective activation of alternatively used splice acceptors by the human immunodeficiency virus type-1 bidirectional splicing enhancer
Corinna Asang, I. Hauber, H. Schaal
2008Nucleic Acids Research41 citations Open access
Semantic Scholar
Improved targeting of human CD4+ T cells by nanobody-modified AAV2 gene therapy vectors
Martin V. Hamann, N. Beschorner, Xuan-Khang Vu, I. Hauber +8 more
2021PLoS ONE34 citations Open access
Semantic Scholar
Anti-inflammatory properties of human serum IgA: induction of IL-1 receptor antagonist and Fc alpha R (CD89)-mediated down-regulation of tumour necrosis factor-alpha (TNF-alpha) and IL-6 in human monocytes.
H. Wolf, I. Hauber, H. Gulle, A. Samstag +3 more
1996Clinical and Experimental Immunology33 citations
Semantic Scholar
Improving Lentiviral Transduction of CD34+ Hematopoietic Stem and Progenitor Cells
I. Hauber, N. Beschorner, Silke Schrödel, J. Chemnitz +3 more
2018Human Gene Therapy Methods32 citations
Semantic Scholar
The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria—inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase
S. Specht, S. R. Sarite, I. Hauber, J. Hauber +5 more
2008Parasitology Research32 citations
Semantic Scholar
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.
T. Goebel, D. Ulmer, Holger Projahn, Jessica Kloeckner +10 more
2008Journal of Medicinal Chemistry28 citations
Semantic Scholar
Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity.
Birgit Schäfer, I. Hauber, Andrea Bunk, J. Heukeshoven +3 more
2006Journal of Infectious Diseases23 citations Open access
Semantic Scholar
Impaired TCR signal transduction, but normal antigen presentation, in a patient with common variable immunodeficiency
M. B. Fischer, I. Hauber, H. Wolf, E. Vogel +2 more
1994British Journal of Haematology21 citations
Semantic Scholar
Preventing Fusarium head blight of wheat and cob rot of maize by inhibition of fungal deoxyhypusine synthase.
M. Woriedh, I. Hauber, A. Martínez-Rocha, C. Voigt +5 more
2011Molecular Plant-Microbe Interactions16 citations Open access
Semantic Scholar
Screening Assay for the Identification of Deoxyhypusine Synthase Inhibitors
Marc N Sommer, D. Bevec, B. Klebl, Birgit Flicke +5 more
2004Journal of biomolecular screening16 citations Open access
Semantic Scholar
Human immunodeficiency virus type 1 infection after sexual abuse: value of nucleic acid sequence analysis in identifying the offender.
S. Banaschak, Marianne Werwein, B. Brinkmann, I. Hauber
2000Clinical Infectious Diseases16 citations
Semantic Scholar
DUAL AND OPPOSITE EFFECTS OF hRAD51 CHEMICAL MODULATION ON HIV-1 INTEGRATION
S. Thierry, M. S. Benleulmi, L. Sinzelle, E. Thierry +15 more
2015Chemistry and Biology14 citations Open access
Semantic Scholar
Reduced IL‐2 Expression Upon Antigen Stimulation is Accompanied by Deficient IL‐9 Gene Expression in T Cells of Patients with CVID
I. Hauber, M. B. Fischer, M. Maris, M. Eibl
1995Scandinavian Journal of Immunology14 citations
Semantic Scholar
The karyopherin CRM1 is required for dendritic cell maturation.
J. Chemnitz, Nadine M. Turza, I. Hauber, A. Steinkasserer +1 more
2010Immunobiology11 citations Open access
Semantic Scholar
Universal Tre (uTre) recombinase specifically targets the majority of HIV-1 isolates
J. Karpinski, J. Chemnitz, I. Hauber, J. Abi-Ghanem +8 more
2014Journal of the International AIDS Society10 citations Open access
Semantic Scholar
Occupational HIV infection documented by sequence analysis of source and index virus strains
B. Salzberger, W. Wiesel, E. Schwingel, I. Hauber
2000HIV Medicine8 citations
Semantic Scholar
Determination of HIV-1 circular DNA as a surrogate marker for residual virus replication in patients with undetectable virus loads.
I. Hauber, T. Harrer, P. Löw, M. Schmitt +2 more
2000AIDS (London)8 citations Open access
Semantic Scholar
Patient-adapted, specific activation of HIV-1 by customized TAL effectors (TALEs), a proof of principle study.
René Geissler, I. Hauber, Nancy Funk, Annekatrin Richter +9 more
2015Virology7 citations Open access
Semantic Scholar
T cell differentiation and generation of the antigen‐specific T cell repertoire in man: observations in MHC class II deficiency
J. Mannhalter, H. Wolf, I. Hauber, M. Miricka +2 more
1994Clinical and Experimental Immunology6 citations Open access
Semantic Scholar
Activation of CVID patients' T cells with conventional antigens and superantigens.
M. Fischer, I. Hauber, H. Eggenbauer, V. Thon +4 more
1993Immunodeficiency5 citations
Semantic Scholar
Next-generation LTR-specific Tre-recombinase targets a majority of HIV-1 isolates
J. Hauber, J. Karpinski, I. Hauber, J. Chemnitz +5 more
2014BMC Infectious Diseases4 citations Open access
Semantic Scholar
Patients with common variable immunodeficiency (CVID) display aberrant IL-2 and IFN-gamma mRNA levels.
I. Hauber, M. Fischer, M. Eibl
1993Immunodeficiency4 citations
Semantic Scholar
Preclinical toxicity analyses of lentiviral vectors expressing the HIV-1 LTR-specific designer-recombinase Brec1
N. Beschorner, Paul Künzle, Maike Voges, I. Hauber +15 more
2024PLoS ONE1 citations Open access
Semantic Scholar
565. CCR5-Uco-TALEN – A Novel Transcription Activator-Like Effector Nuclease That Mediates High-Efficiency Knockout of HIV Co-Receptor CCR5 in Primary T Cells After mRNA Transfection
Ulrike Mock, Rafał Machowicz, I. Hauber, S. Horn +4 more
20151 citations Open access
Semantic Scholar
Personalizing humanized mice with cells obtained from an HIV post treatment controller
I. Hauber, J. S. zur Wiesch, U. Schuhmacher, Carola Schäfer +2 more
2014BMC Infectious Diseases1 citations Open access
Semantic Scholar
[Revolutionizing HIV-therapy by Tre-Recombinase? Initial observations and current state of development].
J. Hauber, I. Hauber, F. Buchholz
2013MMW, Fortschritte der Medizin1 citations
Semantic Scholar
G-107 Pronounced antiviral activity of next-generation LTR-specific Tre-recombinase
Carola Schäfer, J. Karpinski, I. Hauber, J. Chemnitz +5 more
20140 citations
Semantic Scholar
Excision of HIV-1 Proviral DNA using Tre-Recombinase: An Experimental Update
J. Chemnitz, Patrick Ziegler, I. Hauber, Claus-Henning Nagel +4 more
20100 citations
Semantic Scholar
Combination of Imatinib and Hypusination Inhibitors Represents a Novel Therapeutic Strategy in Bcr-Abl Positive Leukemias.
S. Balabanov, Artur Gontarewicz, Patrick Ziegler, U. Hartmann +9 more
20060 citations
Semantic Scholar

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