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M. Lakso · SciRah

Researcher profile · Semantic Scholar

M. Lakso

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M. Lakso — researcher profile on SciRah

h-index: 28
Works: 57
Citations: 7,540

Most-cited papers

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.
Xiaojuan Meng, Maria Lindahl, M. Hyvönen, M. Parvinen +10 more
2000Science1,439 citations
Semantic Scholar
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice.
M. Jeltsch, A. Kaipainen, V. Joukov, Xiaojuan Meng +6 more
1997Science1,340 citations Open access
Semantic Scholar
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.
M. Lakso, J. Pichel, J. Gorman, B. Sauer +4 more
1996Proceedings of the National Academy of Sciences of the United States of America1,176 citations Open access
Semantic Scholar
Targeted oncogene activation by site-specific recombination in transgenic mice.
M. Lakso, B. Sauer, B. Mosinger, Eric J. Lee +4 more
1992Proceedings of the National Academy of Sciences of the United States of America722 citations Open access
Semantic Scholar
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein
M. Lakso, S. Vartiainen, A. Moilanen, J. Sirviö +4 more
2003Journal of Neurochemistry424 citations
Semantic Scholar
Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor.
Jari Rossi, K. Luukko, D. Poteryaev, A. Laurikainen +10 more
1999Neuron297 citations Open access
Semantic Scholar
Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory.
Marko Kaksonen, I. Pavlov, V. Võikar, S. Lauri +5 more
2002Molecular and cellular neurosciences172 citations
Semantic Scholar
The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain.
Marketa Marvanova, M. Lakso, J. Pirhonen, H. Nawa +2 more
2001Molecular and cellular neurosciences156 citations
Semantic Scholar
Osteoblast Recruitment and Bone Formation Enhanced by Cell Matrix–associated Heparin-binding Growth-associated Molecule (HB-GAM)
Shinji Imai, Marko Kaksonen, E. Raulo, Tarja K. Kinnunen +4 more
1998Journal of Cell Biology135 citations Open access
Semantic Scholar
Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds.
L. Häkkinen, L. Koivisto, H. Gardner, U. Saarialho-Kere +6 more
2004American Journal of Pathology130 citations Open access
Semantic Scholar
Overexpression of VEGF in Testis and Epididymis Causes Infertility in Transgenic Mice: Evidence for Nonendothelial Targets for VEGF
E. Korpelainen, Marika J. Karkkainen, Auri Tenhunen, M. Lakso +4 more
1998Journal of Cell Biology127 citations Open access
Semantic Scholar
Embryonic expression of nm23 during mouse organogenesis.
M. Lakso, P. Steeg, H. Westphal
1992Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research98 citations
Semantic Scholar
Global microRNA Expression Profiling of Caenorhabditis elegans Parkinson's Disease Models
Suvi Asikainen, M. Rudgalvytė, Liisa Heikkinen, K. Louhiranta +3 more
2010Journal of Molecular Neuroscience93 citations
Semantic Scholar
Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein.
S. Vartiainen, P. Pehkonen, M. Lakso, Richard Nass +1 more
2006Neurobiology of Disease79 citations Open access
Semantic Scholar
Antipsychotic drug treatment induces differential gene expression in the rat cortex
O. Kontkanen, P. Törönen, M. Lakso, Garry Wong +1 more
2002Journal of Neurochemistry79 citations Open access
Semantic Scholar
The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481]
P. Barter, J. Best, P. Colman, M. d'Emden +15 more
2004Cardiovascular Diabetology76 citations Open access
Semantic Scholar
The Draft Genome and Transcriptome of Panagrellus redivivus Are Shaped by the Harsh Demands of a Free-Living Lifestyle
Jagan Srinivasan, A. Dillman, M. Macchietto, Liisa Heikkinen +6 more
2013Genetics74 citations Open access
Semantic Scholar
Overexpression of the full-length neurotrophin receptor trkB regulates the expression of plasticity-related genes in mouse brain.
E. Koponen, M. Lakso, E. Castrén
2004Brain Research. Molecular Brain Research74 citations
Semantic Scholar
Selective sensitivity of Caenorhabditis elegans neurons to RNA interference
Suvi Asikainen, S. Vartiainen, M. Lakso, Richard Nass +1 more
2005NeuroReport73 citations
Semantic Scholar
Targeted Expression of a Toxin Gene to D1 Dopamine Receptor Neurons by Cre-Mediated Site-Specific Recombination
J. Drago, P. Padungchaichot, J. Y. F. Wong, A. Lawrence +8 more
1998Journal of Neuroscience65 citations Open access
Semantic Scholar
Determination of endocannabinoids in nematodes and human brain tissue by liquid chromatography electrospray ionization tandem mass spectrometry.
M. Lehtonen, M. Storvik, H. Malinen, P. Hyytiä +4 more
2011Journal of chromatography. B, Analytical technologies in the biomedical and life sciences60 citations
Semantic Scholar
Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA.
M. Noshiro, M. Lakso, K. Kawajiri, M. Negishi
1988Biochemistry55 citations
Semantic Scholar
Expression of neurotrophins BDNF and NT-3, and their receptors in rat brain after administration of antipsychotic and psychotrophic agents
A. Linden, Jussi Väisänen, M. Lakso, H. Nawa +2 more
2000Journal of Molecular Neuroscience52 citations
Semantic Scholar
Chronic Antipsychotic Drug Treatment Induces Long-lasting Expression of fos and jun Family Genes and Activator Protein 1 Complex in the Rat Prefrontal Cortex
O. Kontkanen, M. Lakso, Garry Wong, E. Castrén
2002Neuropsychopharmacology46 citations
Semantic Scholar
Identification of Genes Regulated by Memantine and MK-801 in Adult Rat Brain by cDNA Microarray Analysis
Marketa Marvanova, M. Lakso, Garry Wong
2004Neuropsychopharmacology45 citations
Semantic Scholar
Induction of cAMP response element modulator (CREM) and inducible cAMP early repressor (ICER) expression in rat brain by uncompetitive N-methyl-D-aspartate receptor antagonists.
M. Storvik, A. Linden, O. Kontkanen, M. Lakso +2 more
2000Journal of Pharmacology and Experimental Therapeutics35 citations
Semantic Scholar
Excitatory Actions of NMDA Receptor Antagonists in Rat Entorhinal Cortex and Cultured Entorhinal Cortical Neurons
Jussi Väisänen, A. Linden, M. Lakso, Garry Wong +2 more
1999Neuropsychopharmacology34 citations
Semantic Scholar
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans.
Linjing Shen, Changliang Wang, Liang Chen, Ka-Lai Leung +3 more
2020Biochimica et Biophysica Acta - Molecular Basis of Disease32 citations Open access
Semantic Scholar
Methylmercury exposure increases lipocalin related (lpr) and decreases activated in blocked unfolded protein response (abu) genes and specific miRNAs in Caenorhabditis elegans
M. Rudgalvytė, N. VanDuyn, Vuokko Aarnio, Liisa Heikkinen +4 more
2013Toxicology Letters28 citations Open access
Semantic Scholar
Chronic MeHg exposure modifies the histone H3K4me3 epigenetic landscape in Caenorhabditis elegans.
M. Rudgalvytė, Juhani Peltonen, M. Lakso, Garry Wong
2017Comparative biochemistry and physiology. Toxicology & pharmacology : CBP27 citations Open access
Semantic Scholar
Caenorhabditis Elegans Mutants Predict Regulation of Fatty Acids and Endocannabinoids by the CYP-35A Gene Family
Vuokko Aarnio, M. Lehtonen, M. Storvik, J. Callaway +2 more
2011Frontiers in Pharmacology27 citations Open access
Semantic Scholar
Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans.
Vuokko Aarnio, M. Storvik, M. Lehtonen, Suvi Asikainen +5 more
2010Comparative biochemistry and physiology. Toxicology & pharmacology : CBP27 citations
Semantic Scholar
Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP+ Toxicity-Induced Parkinson's Disease Models
Š. Lehtonen, Merja Jaronen, P. Vehviläinen, M. Lakso +6 more
2016Antioxidants and Redox Signaling26 citations
Semantic Scholar
Whole genome microarray analysis of C. elegans rrf‐3 and eri‐1 mutants
Suvi Asikainen, M. Storvik, M. Lakso, Garry Wong
2007FEBS Letters25 citations
Semantic Scholar
Increased lifespan in transgenic Caenorhabditis elegans overexpressing human alpha-synuclein.
S. Vartiainen, Vuokko Aarnio, M. Lakso, Garry Wong
2006Experimental Gerontology24 citations
Semantic Scholar
Overexpression of SUMO perturbs the growth and development of Caenorhabditis elegans
M. Rytinki, M. Lakso, P. Pehkonen, Vuokko Aarnio +4 more
2011Cellular and Molecular Life Sciences19 citations Open access
Semantic Scholar
Chronic Ethanol Exposure Increases Cytochrome P‐450 and Decreases Activated in Blocked Unfolded Protein Response Gene Family Transcripts in Caenorhabditis elegans
Juhani Peltonen, Vuokko Aarnio, Liisa Heikkinen, M. Lakso +1 more
2013Journal of biochemical and molecular toxicology17 citations
Semantic Scholar
RNA‐Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans
M. Rudgalvytė, Juhani Peltonen, M. Lakso, Richard Nass +1 more
2015Journal of biochemical and molecular toxicology16 citations Open access
Semantic Scholar
Trans fat diet causes decreased brood size and shortened lifespan in Caenorhabditis elegans delta‐6‐desaturase mutant fat‐3
Kaja Reisner, M. Lehtonen, M. Storvik, Tanel Jantson +3 more
2011Journal of biochemical and molecular toxicology16 citations Open access
Semantic Scholar
1H MR spectroscopic imaging of phospholipase‐mediated membrane lipid release in apoptotic rat glioma in vivo
T. Liimatainen, A. Erkkila, P. Valonen, H. Vidgren +5 more
2008Magnetic Resonance in Medicine16 citations
Semantic Scholar
Uncompetitive Antagonists of the N‐Methyl‐D‐aspartate (NMDA) Receptors Alter the mRNA Expression of Proteins Associated with the NMDA Receptor Complex
A. Linden, Jussi Väisänen, M. Storvik, M. Lakso +3 more
200116 citations
Semantic Scholar
PIWI-interacting RNA expression regulates pathogenesis in a Caenorhabditis elegans model of Lewy body disease
Xiao-Bing Huang, Changliang Wang, Tian-Jiao Zhang, Rongzhen Li +6 more
2023Nature Communications14 citations Open access
Semantic Scholar
Expression Profiling to Understand Actions of NMDA/Glutamate Receptor Antagonists in Rat Brain
P. Törönen, M. Storvik, A. Linden, O. Kontkanen +4 more
2002Neurochemical Research11 citations
Semantic Scholar
Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801.
A. Linden, M. Storvik, M. Lakso, A. Haapasalo +5 more
2001Neuropharmacology9 citations
Semantic Scholar
Synexpression analysis of ESTs in the rat brain reveals distinct patterns and potential drug targets.
Marketa Marvanova, P. Törönen, M. Storvik, M. Lakso +2 more
2002Brain Research. Molecular Brain Research8 citations
Semantic Scholar
Molecular Effects of the Psychotropic NMDA Receptor Antagonist MK‐801 in the Rat Entorhinal Cortex: Increases in AP‐1 DNA Binding Activity and Expression of Fos and Jun Family Members
O. Kontkanen, M. Lakso, E. Koponen, Garry Wong +1 more
2000Annals of the New York Academy of Sciences8 citations
Semantic Scholar
Transcriptional profiling reveals differential expression of a neuropeptide-like protein and pseudogenes in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans.
Vuokko Aarnio, Liisa Heikkinen, Juhani Peltonen, G. Goldsteins +2 more
2014Comparative Biochemistry and Physiology - Part D:Genomics and Proteomics6 citations Open access
Semantic Scholar
Subunit selective decrease of AMPA and metabotropic glutamate receptor mRNA expression in rat brain by systemic administration of the NMDA receptor blocker MK-801
M. Storvik, A. Linden, M. Lakso, Garry Wong
2003Journal of Molecular Neuroscience5 citations
Semantic Scholar
A Functional Genomic Study of the Effects of Antipsychotic Agent Chlorpromazine in PC12 Cells
O. Kontkanen, M. Lakso, Garry Wong, E. Castrén
2000Clinical Chemistry and Laboratory Medicine5 citations
Semantic Scholar
The C. elegans gba-3 gene encodes a glucocerebrosidase that exacerbates α-synuclein-mediated impairments in deletion mutants
Ning Liu, Rongzhen Li, Xiao-Bing Huang, M. Lakso +1 more
2025Translational Neurodegeneration2 citations Open access
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E. Castrén×13
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M. Storvik×10
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Vuokko Aarnio×7

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M. Rudgalvytė×6

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