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P. Steeg · SciRah

Researcher profile · Semantic Scholar

P. Steeg

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P. Steeg — researcher profile on SciRah

h-index: 80
Works: 298
Citations: 27K

Most-cited papers

Targeting metastasis
P. Steeg
2016Nature Reviews. Cancer1,247 citations Open access
Semantic Scholar
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
Lin Zhang, Si-Yuan Zhang, Jun Yao, Frank J. Lowery +18 more
2015Nature1,108 citations Open access
Semantic Scholar
Antibody-drug conjugates for cancer.
C. Chau, P. Steeg, W. Figg
2019The Lancet377 citations
Semantic Scholar
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Gonçalo M. C. Rodrigues, A. Hoshino, C. Kenific, Irina R. Matei +43 more
2019Nature Cell Biology369 citations Open access
Semantic Scholar
A framework for the development of effective anti-metastatic agents
R. Anderson, T. Balasas, J. Callaghan, R. Coombes +14 more
2018Nature Reviews Clinical Oncology306 citations Open access
Semantic Scholar
The blood–tumour barrier in cancer biology and therapy
P. Steeg
2021Nature Reviews Clinical Oncology261 citations
Semantic Scholar
CNS Metastases in Breast Cancer: Old Challenge, New Frontiers
N. Lin, L. Amiri-Kordestani, D. Palmieri, D. Liewehr +1 more
2013Clinical Cancer Research198 citations Open access
Semantic Scholar
Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study.
A. Morikawa, D. Peereboom, H. Thorsheim, Ramakrishna Samala +9 more
2015Neuro-Oncology165 citations Open access
Semantic Scholar
Alterations in Pericyte Subpopulations are Associated with Elevated Blood-Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer
L. Lyle, P. Lockman, C. Adkins, A. Mohammad +12 more
2016Clinical Cancer Research157 citations Open access
Semantic Scholar
Endocytosis: a pivotal pathway for regulating metastasis
I. Khan, P. Steeg
2020British Journal of Cancer156 citations Open access
Semantic Scholar
Towards a Drug Development Path that Targets Metastatic Progression in Osteosarcoma
C. Khanna, Timothy M. Fan, R. Gorlick, L. Helman +28 more
2014Clinical Cancer Research143 citations Open access
Semantic Scholar
Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.
J. Marshall, Joshua W. Collins, Joji Nakayama, C. Horak +8 more
2012Journal of the National Cancer Institute131 citations Open access
Semantic Scholar
Src family kinases as novel therapeutic targets to treat breast cancer brain metastases
Si-Yuan Zhang, Wen-Chien Huang, Lin Zhang, Chenyu Zhang +9 more
2013Cancer Research115 citations Open access
Semantic Scholar
Brain Metastasis Cell Lines Panel: a public resource of organotropic cell lines
M. Valiente, Amanda E. D. Van Swearingen, C. Anders, A. Bairoch +22 more
2020Cancer Research89 citations Open access
Semantic Scholar
Perspective: The right trials
P. Steeg
2012Nature89 citations Open access
Semantic Scholar
TPI-287, a New Taxane Family Member, Reduces the Brain Metastatic Colonization of Breast Cancer Cells
D. Fitzgerald, D. Emerson, Yongzhen Qian, T. Anwar +5 more
2012Molecular Cancer Therapeutics87 citations Open access
Semantic Scholar
Paclitaxel-Hyaluronic Nano-Conjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model
R. Mittapalli, Xinli Liu, C. Adkins, M. Nounou +8 more
2013Molecular Cancer Therapeutics84 citations Open access
Semantic Scholar
Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism
C. Sartorius, Colton Hanna, B. Gril, Hazel Cruz +7 more
2015Oncogene75 citations Open access
Semantic Scholar
Roadblocks to translational advances on metastasis research
T. Brabletz, D. Lyden, P. Steeg, Z. Werb
2013Nature Medicine75 citations Open access
Semantic Scholar
DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer.
S. Woditschka, L. Evans, R. Duchnowska, L. T. Reed +18 more
2014Journal of the National Cancer Institute72 citations Open access
Semantic Scholar
Metastasis suppressors: functional pathways
I. Khan, P. Steeg
2017Laboratory Investigation68 citations Open access
Semantic Scholar
Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner
D. Palmieri, R. Duchnowska, S. Woditschka, Emily Hua +10 more
2014Clinical Cancer Research66 citations Open access
Semantic Scholar
Dipyridamole prevents triple-negative breast-cancer progression
D. Spano, J. Marshall, Natascia Marino, Daniela De Martino +9 more
2012Clinical and Experimental Metastasis60 citations Open access
Semantic Scholar
Opposing Effects of Pigment Epithelium-Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage
D. Fitzgerald, Preeti Subramanian, M. Deshpande, Christian Graves +11 more
2012Cancer Research57 citations Open access
Semantic Scholar
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer
Y. Greer, Samuel F. Gilbert, B. Gril, R. Narwal +4 more
2019Breast Cancer Research55 citations Open access
Semantic Scholar
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity
Ryan P. McMullin, B. Wittner, Chuanwei Yang, Benjamin R Denton-Schneider +10 more
2014Breast Cancer Research54 citations Open access
Semantic Scholar
Nm23-H1 binds gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis
Natascia Marino, J. Marshall, Joshua W. Collins, Ming Zhou +3 more
2013Cancer Research54 citations Open access
Semantic Scholar
FMN2 makes perinuclear actin to protect nuclei during confined migration and promote metastasis
Colleen T. Skau, Robert S. Fischer, P. Gurel, H. Thiam +8 more
2016Cell50 citations Open access
Semantic Scholar
A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival
L. Hernandez, M. Kim, A. M. Noonan, E. Sagher +7 more
2015Cell Death Discovery49 citations Open access
Semantic Scholar
Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility and Metastasis.
I. Khan, B. Gril, P. Steeg
2019Cancer Research45 citations Open access
Semantic Scholar
Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients
R. Duchnowska, J. Jassem, C. Goswami, Murat Dundar +13 more
2015Journal of Neuro-Oncology42 citations Open access
Semantic Scholar
Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer
J. Nair, Tzu-Ting Huang, J. Murai, Brittany M. Haynes +3 more
2020Oncogene40 citations Open access
Semantic Scholar
Identification and Validation of Genes with Expression Patterns Inverse to Multiple Metastasis Suppressor Genes in Breast Cancer Cell Lines
Natascia Marino, Joshua W. Collins, Chang-Yu Shen, N. Caplen +7 more
2014Clinical and Experimental Metastasis39 citations Open access
Semantic Scholar
Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis
S. M. Saldana, Heng-Huan Lee, Frank J. Lowery, Y. Khotskaya +7 more
2013PLoS ONE38 citations Open access
Semantic Scholar
The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities
I. Khan, P. Steeg
2017OncoTarget32 citations Open access
Semantic Scholar
AACR Cancer Progress Report 2012
L. Cantley, W. Dalton, R. DuBois, O. Finn +10 more
2012Clinical Cancer Research32 citations Open access
Semantic Scholar
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor
M. Lacombe, F. Lamarche, O. De Wever, T. Padilla-Benavides +25 more
2021BMC Biology31 citations Open access
Semantic Scholar
Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs
A. Berghoff, Yunxiang Liao, M. Karreman, A. Ilhan-Mutlu +25 more
2020Molecular Cancer Research31 citations Open access
Semantic Scholar
Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma
Jun S. Wei, P. Johansson, Li Chen, Young K. Song +13 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.
A. Zimmer, S. Steinberg, D. Smart, M. Gilbert +10 more
2020Future Oncology30 citations Open access
Semantic Scholar
Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis
D. Smart, Alejandra Garcia-Glaessner, D. Palmieri, Sarah J. E. Wong-Goodrich +8 more
2015Clinical and Experimental Metastasis30 citations Open access
Semantic Scholar
A HER2 Antibody Drug Conjugate Controls Growth of Breast Cancer Brain Metastases in Hematogenous Xenograft Models, with Heterogeneous Blood-Tumor Barrier Penetration Unlinked to a Passive Marker.
B. Gril, D. Wei, A. Zimmer, C. Robinson +4 more
2020Neuro-Oncology28 citations Open access
Semantic Scholar
Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer
Ramakrishna Samala, H. Thorsheim, Satyanarayana Goda, Kunal S. Taskar +3 more
2016Pharmaceutical Research27 citations Open access
Semantic Scholar
National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities
Michelle M. Kim, M. Mehta, D. Smart, P. Steeg +40 more
2023The Lancet Oncology26 citations Open access
Semantic Scholar
Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis
A. Wu, Selamawit Gossa, Ramakrishna Samala, Monika Chung +17 more
2021Clinical Cancer Research23 citations Open access
Semantic Scholar
Clinical evidence for drug penetration of capecitabine and lapatinib uptake in resected brain metastases from women with metastatic breast cancer.
A. Morikawa, D. Peereboom, Q. Smith, H. Thorsheim +6 more
201321 citations
Semantic Scholar
Analysis of breast cancer in young women in the Department of Defense (DOD) database
A. Zimmer, K. Zhu, P. Steeg, A. Wu +9 more
2017Breast Cancer Research and Treatment20 citations Open access
Semantic Scholar
Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified
T. Hsu, P. Steeg, M. Zollo, T. Wieland
2015Naunyn-Schmiedeberg's Archives of Pharmacology19 citations Open access
Semantic Scholar
Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases
Sarah Jenkins, Wei Zhang, S. Steinberg, Darryl Nousome +23 more
2023Clinical Cancer Research18 citations Open access
Semantic Scholar
Meaningful prevention of breast cancer metastasis: candidate therapeutics, preclinical validation, and clinical trial concerns
A. Zimmer, P. Steeg
2014Journal of molecular medicine13 citations Open access
Semantic Scholar

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B. Gril×13
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B. Gril — researcher profile on SciRah
D. Palmieri×10
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S. Steinberg×7
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D. Liewehr×6
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Yongzhen Qian×6

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H. Thorsheim×4

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