Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Christoph Loenarz · SciRah

Researcher profile · Semantic Scholar

Christoph Loenarz

Share profile

Christoph Loenarz — researcher profile on SciRah

h-index: 25
Works: 48
Citations: 3,836

Most-cited papers

Expanding chemical biology of 2-oxoglutarate oxygenases.
Christoph Loenarz, C. Schofield
2008Nature Chemical Biology503 citations
Semantic Scholar
Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study.
N. Burgess-Brown, Sujata Sharma, F. Sobott, Christoph Loenarz +2 more
2008Protein Expression and Purification348 citations
Semantic Scholar
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.
Patrick J. Pollard, Christoph Loenarz, D. Mole, M. McDonough +3 more
2008Biochemical Journal301 citations Open access
Semantic Scholar
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases.
Christoph Loenarz, C. Schofield
2011TIBS -Trends in Biochemical Sciences. Regular ed273 citations
Semantic Scholar
Structural studies on human 2-oxoglutarate dependent oxygenases.
M. McDonough, Christoph Loenarz, R. Chowdhury, I. Clifton +1 more
2010Current Opinion in Structural Biology268 citations
Semantic Scholar
The hypoxia‐inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
Christoph Loenarz, Mathew L. Coleman, A. Boleininger, B. Schierwater +3 more
2011EMBO Reports245 citations Open access
Semantic Scholar
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
R. Chowdhury, M. McDonough, Jasmin Mecinović, Christoph Loenarz +4 more
2009Structure232 citations Open access
Semantic Scholar
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase
Christoph Loenarz, W. Ge, Mathew L. Coleman, Nathan R. Rose +4 more
2009Human Molecular Genetics169 citations Open access
Semantic Scholar
Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family
Lars Hillringhaus, W. Yue, Nathan R. Rose, S. Ng +6 more
2011Journal of Biological Chemistry158 citations Open access
Semantic Scholar
Oxygenase Catalysed Ribosome Hydroxylation Occurs in Prokaryotes and Humans
W. Ge, Alexander Wolf, Tianshu Feng, Chia-Hua Ho +28 more
2012Nature Chemical Biology149 citations Open access
Semantic Scholar
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
Armin Thalhammer, Zuzana Bencokova, Rachel L. Poole, Christoph Loenarz +9 more
2011PLoS ONE145 citations Open access
Semantic Scholar
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
Christoph Loenarz, R. Sekirnik, Armin Thalhammer, W. Ge +8 more
2014Proceedings of the National Academy of Sciences of the United States of America125 citations Open access
Semantic Scholar
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
R. Singleton, Phebee Liu-Yi, F. Formenti, W. Ge +15 more
2014Proceedings of the National Academy of Sciences of the United States of America120 citations Open access
Semantic Scholar
Oxygenase catalyzed 5-methylcytosine hydroxylation.
Christoph Loenarz, C. Schofield
2009Chemistry and Biology89 citations Open access
Semantic Scholar
A mechanism for induction of a hypoxic response by vaccinia virus
Michela Mazzon, Nicholas E. Peters, Christoph Loenarz, E. Krysztofinska +3 more
2013Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Kinetic Rationale for Selectivity toward N- and C-terminal Oxygen-dependent Degradation Domain Substrates Mediated by a Loop Region of Hypoxia-Inducible Factor Prolyl Hydroxylases*
E. Flashman, E. A. Bagg, R. Chowdhury, Jasmin Mecinović +4 more
2008Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Evidence for a stereoelectronic effect in human oxygen sensing.
Christoph Loenarz, Jasmin Mecinović, R. Chowdhury, Luke A. McNeill +2 more
2009Angewandte Chemie65 citations
Semantic Scholar
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates
Armin Thalhammer, Jasmin Mecinović, Christoph Loenarz, A. Tumber +3 more
2010Organic and biomolecular chemistry51 citations Open access
Semantic Scholar
Identification and Characterization of a Novel Evolutionarily Conserved Lysine-specific Methyltransferase Targeting Eukaryotic Translation Elongation Factor 2 (eEF2)*
E. Davydova, A. Ho, J. Malecki, A. Moen +4 more
2014Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
M. Katz, Julieta M. Acevedo, Christoph Loenarz, Diego Galagovsky +13 more
2014Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.
C. Stubbs, Christoph Loenarz, Jasmin Mecinović, K. Yeoh +5 more
2009Journal of Medicinal Chemistry46 citations
Semantic Scholar
Crystal structure of the PHF8 Jumonji domain, an N ε‐methyl lysine demethylase
W. Yue, V. Hozjan, W. Ge, Christoph Loenarz +5 more
2010FEBS Letters36 citations
Semantic Scholar
Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases
S. Horita, J. S. Scotti, C. Thinnes, Yousef S. Mottaghi-Taromsari +6 more
2015Structure33 citations Open access
Semantic Scholar
2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.
Jasmin Mecinović, Christoph Loenarz, R. Chowdhury, C. Schofield
2009Bioorganic & Medicinal Chemistry Letters28 citations Open access
Semantic Scholar
Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.
A. Conejo-García, M. McDonough, Christoph Loenarz, Luke A. McNeill +5 more
2010Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase
James E. Longbotham, C. Levy, L. Johannissen, H. Tarhonskaya +6 more
2015Biochemistry23 citations Open access
Semantic Scholar
A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique Cα‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase
Jana Gagsteiger, S. Jahn, Lorenz Heidinger, Lukas Gericke +4 more
2022Angewandte Chemie21 citations Open access
Semantic Scholar
Biomimetic S‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes **
Lukas Gericke, D. Mhaindarkar, Lukas Karst, S. Jahn +12 more
2023ChemBioChem19 citations Open access
Semantic Scholar
Chemical basis for the selectivity of the von Hippel Lindau tumor suppressor pVHL for prolyl-hydroxylated HIF-1alpha.
Christopher J. R. Illingworth, Christoph Loenarz, C. Schofield, C. Domene
2010Biochemistry18 citations
Semantic Scholar
Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases.
B. M. R. Liénard, A. Conejo-García, Ineke P. Stolze, Christoph Loenarz +3 more
2008Chemical Communications16 citations
Semantic Scholar
Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens
K. Lippl, A. Boleininger, M. McDonough, M. Abboud +4 more
2018Hypoxia14 citations Open access
Semantic Scholar
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner
Verena B. Eisenbeis, Danye Qiu, O. Gorka, L. Strotmann +9 more
2023Proceedings of the National Academy of Sciences of the United States of America10 citations Open access
Semantic Scholar
Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding
C. Thinnes, C. Lohans, M. Abboud, T. Yeh +7 more
2019Chemistry10 citations Open access
Semantic Scholar
Non‐canonical nucleosides: Biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure
Patricia Benčić, Michael Keppler, Marco Kuge, Danye Qiu +6 more
2023The FEBS Journal9 citations Open access
Semantic Scholar
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase
R. Sekirnik, S. E. Wilkins, Jacob T. Bush, H. Tarhonskaya +7 more
2018Extremophiles6 citations Open access
Semantic Scholar
Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
D. Rotili, Mikael Altun, Refaat B. Hamed, Christoph Loenarz +7 more
2011Chemical Communications6 citations
Semantic Scholar
An Oxygen Sensation: Progress in Macromolecule Hydroxylation Triggered by the Elucidation of Cellular Oxygen Sensing.
Christoph Loenarz
2020Angewandte Chemie5 citations
Semantic Scholar
Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain
M. Abboud, R. Chowdhury, I. Leung, K. Lippl +3 more
2018ChemBioChem5 citations Open access
Semantic Scholar
β-Lapachone Regulates Mammalian Inositol Pyrophosphate Levels in an NQO1- and Oxygen-dependent Manner
Verena B. Eisenbeis, Danye Qiu, L. Strotmann, Gui-Zhen Liu +5 more
2022bioRxiv3 citations Open access
Semantic Scholar
Oxygenases for oxygen sensing
Christoph Loenarz, R. Chowdhury, C. Schofield, E. Flashman
20083 citations Open access
Semantic Scholar
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry
A. Kawamura, Christoph Loenarz, C. Schofield
2011Cell Cycle2 citations Open access
Semantic Scholar
Biomimetic S -adenosylmethionine regeneration for nucleophilic and radical alkylation reactions and aminopropyltransfer
Lukas Gericke, D. Mhaindarkar, Lukas Karst, S. Jahn +14 more
20220 citations
Semantic Scholar
Biomimetic S-Adenosylmethionine Regeneration Starting from Different Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes
Lukas Gericke, D. Mhaindarkar, Lukas Karst, S. Jahn +12 more
2022bioRxiv0 citations Open access
Semantic Scholar
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase
R. Sekirnik, S. E. Wilkins, Jacob T. Bush, H. Tarhonskaya +7 more
2018Extremophiles0 citations Open access
Semantic Scholar
The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - Truncated Construct
James E. Longbotham, C. Levy, L. O. Johannisen, H. Tarhonskaya +6 more
20150 citations
Semantic Scholar
Faculty Opinions recommendation of Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.
C. Schofield, Christoph Loenarz
20100 citations
Semantic Scholar
Faculty Opinions recommendation of SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network.
C. Schofield, Christoph Loenarz
20100 citations
Semantic Scholar
Faculty Opinions recommendation of Expanding role of the jumonji C domain as an RNA hydroxylase.
C. Schofield, Christoph Loenarz
20100 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

C. Schofield×35
Invite
C. Schofield — researcher profile on SciRah
M. McDonough×11
Invite
M. McDonough — researcher profile on SciRah
P. Ratcliffe×10
Invite
P. Ratcliffe — researcher profile on SciRah
E. Flashman×10
Invite
E. Flashman — researcher profile on SciRah

×9

Invite

R. Chowdhury — researcher profile on SciRah

Invite

W. Ge — researcher profile on SciRah

Armin Thalhammer×8

Invite

Armin Thalhammer — researcher profile on SciRah

Jasmin Mecinović×6

Invite

Jasmin Mecinović — researcher profile on SciRah

Invite

R. Sekirnik — researcher profile on SciRah

Invite

M. Cockman — researcher profile on SciRah

H. Tarhonskaya×5

Invite

H. Tarhonskaya — researcher profile on SciRah

Invite

J. Andexer — researcher profile on SciRah