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G. Hovingh · SciRah

Researcher profile · Semantic Scholar

G. Hovingh

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G. Hovingh — researcher profile on SciRah

h-index: 80
Works: 467
Citations: 34K

Most-cited papers

Homozygous Familial Hypercholesterolaemia – Worldwide Experience
T. Tromp, M. L. Hartgers, G. Hovingh, Antonio J. Vallejo-Vaz +8 more
2022The Lancet149 citations Open access
Semantic Scholar
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives
F. Kreiner, J. Kraaijenhof, M. von Herrath, G. Hovingh +1 more
2022Expert Review of Clinical Immunology86 citations Open access
Semantic Scholar
Low-density lipoprotein cholesterol, C-reactive protein, and lipoprotein(a) universal one-time screening in primary prevention: the EPIC-Norfolk study
J. Kraaijenhof, N. Nurmohamed, A. Nordestgaard, L. Reeskamp +4 more
2025European Heart Journal62 citations Open access
Semantic Scholar
Marked plaque regression in homozygous familial hypercholesterolemia.
L. Reeskamp, N. Nurmohamed, M. Bom, R. Planken +9 more
2021Atherosclerosis58 citations Open access
Semantic Scholar
Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study.
Kanika I. Dharmayat, A. Vallejo-Vaz, Christophe A. T. Stevens, J. Brandts +481 more
2023The Lancet52 citations Open access
Semantic Scholar
LDL-C calculated by Friedewald, Martin-Hopkins, or NIH equation 2 versus beta-quantification: pooled alirocumab trials
H. Ginsberg, R. Rosenson, G. Hovingh, A. Letierce +3 more
2021Journal of Lipid Research47 citations Open access
Semantic Scholar
PCSK9 inhibition with orally administered NNC0385-0434 in hypercholesterolaemia: a randomised, double-blind, placebo-controlled and active-controlled phase 2 trial.
Michael J. Koren, O. Descamps, Yoshiki Hata, E. Hengeveld +8 more
2024The Lancet Diabetes and Endocrinology38 citations Open access
Semantic Scholar
Efficacy and Safety of K-877 (Pemafibrate), a Selective PPARα Modulator, in European Patients on Statin Therapy.
H. Ginsberg, N. Hounslow, Y. Senko, H. Suganami +6 more
2022Diabetes Care37 citations Open access
Semantic Scholar
Paediatric patients with heterozygous familial hypercholesterolaemia treated with evolocumab for 80 weeks (HAUSER-OLE): a single-arm, multicentre, open-label extension of HAUSER-RCT.
Raul D. Santos, A. Ruzza, G. Hovingh, C. Stefanutti +13 more
2022The Lancet Diabetes and Endocrinology36 citations Open access
Semantic Scholar
Sex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia.
Janneke W. C. M. Mulder, T. Tromp, Mutaz Al-Khnifsawi, D. Blom +13 more
2024JAMA cardiology34 citations Open access
Semantic Scholar
Long-Term Efficacy and Tolerability of PCSK9 Targeted Therapy: A Review of the Literature
Willemijn A. M. Schonck, E. Stroes, G. Hovingh, L. Reeskamp
2024Drugs30 citations Open access
Semantic Scholar
The role of systemic inflammation in remnant cholesterol associated cardiovascular risk: insights from the EPIC-Norfolk study.
J. Kraaijenhof, Marije J. Kerkvliet, N. Nurmohamed, Aldo Grefhorst +6 more
2025European Journal of Preventive Cardiology29 citations Open access
Semantic Scholar
Concordance of a High Lipoprotein(a) Concentration Among Relatives.
L. Reeskamp, T. Tromp, A. Patel, S. Ibrahim +6 more
2023JAMA cardiology29 citations
Semantic Scholar
Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry
Amany Elshorbagy, A. Vallejo-Vaz, F. Barkas, A. R. Lyons +79 more
2025European Heart Journal28 citations Open access
Semantic Scholar
Beyond Early LDL Cholesterol Lowering to Prevent Coronary Atherosclerosis in Familial Hypercholesterolemia.
S. Ibrahim, L. Reeskamp, J. D. de Goeij, G. Hovingh +8 more
2024European Journal of Preventive Cardiology26 citations Open access
Semantic Scholar
Low‐Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific
A. Cupido, F. Asselbergs, A. Schmidt, G. Hovingh
2022Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease23 citations Open access
Semantic Scholar
Polygenic Background Modifies Risk of Coronary Artery Disease Among Individuals With Heterozygous Familial Hypercholesterolemia
L. Reeskamp, I. Shim, J. Dron, S. Ibrahim +7 more
2023JACC: Advances21 citations Open access
Semantic Scholar
Resmetirom (MGL-3196) in Patients With Heterozygous Familial Hypercholesterolemia.
G. Hovingh, I. Klausen, E. Heggen, Kevin D. McCarty +5 more
2022Journal of the American College of Cardiology20 citations Open access
Semantic Scholar
Cardiovascular outcomes in patients with homozygous familial hypercholesterolaemia on lipoprotein apheresis initiated during childhood: a long-term follow-up of an international cohort from two registries
M. D. Reijman, T. Tromp, B. Hutten, G. Hovingh +13 more
2024The Lancet Child & Adolescent Health17 citations Open access
Semantic Scholar
Plasma C-reactive protein is associated with a pro-inflammatory and adverse plaque phenotype.
J. Kraaijenhof, B. Mol, N. Nurmohamed, K. Dzobo +6 more
2024Atherosclerosis17 citations Open access
Semantic Scholar
Implications of ACC/AHA Versus ESC/EAS LDL-C Recommendations for Residual Risk Reduction in ASCVD: A Simulation Study From DA VINCI
A. Vallejo-Vaz, S. Bray, G. Villa, J. Brandts +26 more
2022Cardiovascular Drugs and Therapy17 citations Open access
Semantic Scholar
Use of Lipoprotein(a) to improve diagnosis and management in clinical familial hypercholesterolemia.
T. Tromp, S. Ibrahim, N. Nurmohamed, J. Peter +5 more
2022Atherosclerosis16 citations Open access
Semantic Scholar
Cognitive function with evolocumab in pediatric heterozygous familial hypercholesterolemia.
D. Gaudet, A. Ruzza, I. Bridges, P. Maruff +11 more
2022Journal of Clinical Lipidology14 citations Open access
Semantic Scholar
Intronic variant screening with targeted next-generation sequencing reveals first pseudoexon in LDLR in familial hypercholesterolemia.
L. Reeskamp, Manon Balvers, J. Peter, Laura van de Kerkhof +7 more
2021Atherosclerosis13 citations Open access
Semantic Scholar
Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study.
Amany Elshorbagy, A. R. Lyons, A. Vallejo-Vaz, Christophe A. T. Stevens +496 more
2024The Lancet Diabetes and Endocrinology12 citations Open access
Semantic Scholar
Age- and sex-based heterogeneity in coronary artery plaque presence and burden in familial hypercholesterolemia: A multi-national study
Khurram Nasir, Reed Mszar, M. Cainzos-Achirica, Gowtham R. Grandhi +15 more
2023American Journal of Preventive Cardiology12 citations Open access
Semantic Scholar
Assessment of practical applicability and clinical relevance of a commonly used LDL-C polygenic score in patients with severe hypercholesterolemia.
T. Tromp, A. Cupido, L. Reeskamp, E. Stroes +4 more
2021Atherosclerosis12 citations Open access
Semantic Scholar
Interleukin 6 plasma levels are associated with progression of coronary plaques
J. Kraaijenhof, N. Nurmohamed, E. Tzolos, Me-Ah Mo +6 more
2024Open Heart11 citations Open access
Semantic Scholar
Angiopoietin-like 3 inhibition and the liver: less is more?
R. Oostveen, G. Hovingh, E. Stroes
2023Current Opinion in Lipidology11 citations Open access
Semantic Scholar
LDLR Variant Classification for Improved Cardiovascular Risk Prediction in Familial Hypercholesterolemia
S. Ibrahim, M. L. Hartgers, L. Reeskamp, Linda C. Zuurbier +5 more
2023medRxiv11 citations Open access
Semantic Scholar
Decreased LDL-Cholesterol Exposure Following ANGPTL3 Inhibition Reduces Coronary Plaque Development in Homozygous Familial Hypercholesterolemia.
Willemijn A. M. Schonck, M. D. Reijman, A. Wiegman, S. Ibrahim +6 more
2024JACC Cardiovascular Imaging10 citations Open access
Semantic Scholar
Quality of life and coping in Dutch homozygous familial hypercholesterolemia patients: A qualitative study.
J. Mulder, L. Kranenburg, Willemijn J. Treling, G. Hovingh +3 more
2022Atherosclerosis10 citations Open access
Semantic Scholar
High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins
Josefien W. Hommes, Rachel M. Kratofil, S. Wahlen, C. D. de Haas +7 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Homozygous familial hypercholesterolemia is a life limiting condition: medical life-trajectories in the post-2010 era
Janneke W. C. M. Mulder, M. D. Reijman, D. Kusters, Eric Boersma +22 more
2025Journal of the American College of Cardiology9 citations Open access
Semantic Scholar
Evolocumab in paediatric heterozygous familial hypercholesterolaemia: cognitive function during 80 weeks of open-label extension treatment.
Raul D. Santos, A. Ruzza, Bei Wang, P. Maruff +11 more
2023European Journal of Preventive Cardiology9 citations Open access
Semantic Scholar
Plasma proteomics improves prediction of coronary plaque progression
J. Kraaijenhof, N. Nurmohamed, M. Bom, E. Gaillard +7 more
2024European Heart Journal-Cardiovascular Imaging8 citations Open access
Semantic Scholar
Association Between Self‐Rated Medication Adherence and Adverse Cardiovascular Outcomes in Patients With Hypertension
S. Ibrahim, N. Nurmohamed, D. Collard, A. de Weger +5 more
2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease8 citations Open access
Semantic Scholar
ANGPTL3 (Angiopoietin‐Like 3) Preferentially Resides on High‐Density Lipoprotein in the Human Circulation, Affecting Its Activity
J. Kraaijenhof, T. Tromp, N. Nurmohamed, L. Reeskamp +8 more
2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease8 citations Open access
Semantic Scholar
Counseling couples at risk of having a child with homozygous familial hypercholesterolemia - Clinical experience and recommendations.
T. Tromp, M. D. Reijman, A. Wiegman, G. Hovingh +3 more
2022Journal of Clinical Lipidology8 citations Open access
Semantic Scholar
Plasma reduction of apolipoprotein C-III with olezarsen leads to significant reductions in postprandial triglyceride levels: Results from a randomized trial.
J. Kraaijenhof, Merel Peletier, N. Nurmohamed, G. Hovingh +4 more
2025European Journal of Preventive Cardiology7 citations Open access
Semantic Scholar
Evolocumab treatment reduces carotid intima-media thickness in paediatric patients with heterozygous familial hypercholesterolaemia.
A. Wiegman, A. Ruzza, G. Hovingh, Raul D. Santos +9 more
2024European Journal of Preventive Cardiology7 citations Open access
Semantic Scholar
Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
Suzanne E. Engelen, F. Ververs, A. Markovska, B. Lagerholm +21 more
2023JCI Insight7 citations Open access
Semantic Scholar
Adherence to statin treatment in patients with familial hypercholesterolemia: A dynamic prediction model.
A. Cupido, M. Hof, L. D. de Boer, R. Huijgen +4 more
2022Journal of Clinical Lipidology7 citations Open access
Semantic Scholar
iCARE4CVD: an innovative European consortium aiming to improve personalized cardiovascular care
H. Brunner-la Rocca, Dirk Müller-Wieland, G. Hovingh
2025European Heart Journal6 citations Open access
Semantic Scholar
Effect of PCSK9 Inhibition on the Plasma Proteome: A SPIRE SubStudy
J. Kraaijenhof, T. Opstal, J. Cornel, D. Gill +6 more
2023Arteriosclerosis, Thrombosis and Vascular Biology6 citations Open access
Semantic Scholar
Global disparities in access to lipid-lowering therapies for patients with homozygous familial hypercholesterolemia - A physician survey.
Willemijn A. M. Schonck, Janneke W. C. M. Mulder, T. Tromp, L. Reeskamp +3 more
2025Journal of Clinical Lipidology5 citations Open access
Semantic Scholar
Unexpected gaps in knowledge of familial hypercholesterolaemia among Dutch general practitioners
S. Ibrahim, J. D. de Goeij, N. Nurmohamed, J. Pang +9 more
2024Netherlands Heart Journal5 citations Open access
Semantic Scholar
Low-Cost High-Throughput Genotyping for Diagnosing Familial Hypercholesterolemia
S. Ibrahim, J. V. van Rooij, A. Verkerk, Jard de Vries +9 more
2023Circulation Genomic and Precision Medicine5 citations Open access
Semantic Scholar
Evolocumab treatment reduces carotid intima-media thickness in paediatric patients with heterozygous familial hypercholesterolaemia
A. Wiegman, A. Ruzza, G. Hovingh, R. Santos +9 more
2022European Heart Journal4 citations
Semantic Scholar
Impact of cumulative LDL-C and other risk factors on CAD prevalence in patients with familial hypercholesterolemia.
S. Ibrahim, G. Hovingh, B. Hutten, E. Stroes +1 more
2024European Journal of Preventive Cardiology3 citations Open access
Semantic Scholar

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