Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Repa · SciRah

Researcher profile · Semantic Scholar

J. Repa

Share profile

J. Repa — researcher profile on SciRah

h-index: 58
Works: 110
Citations: 27K

Most-cited papers

Identification of a nuclear receptor for bile acids.
M. Makishima, Arthur Y. Okamoto, J. Repa, H. Tu +6 more
1999Science2,697 citations
Semantic Scholar
Nuclear receptors and lipid physiology: opening the X-files.
A. Chawla, J. Repa, Ronald M. Evans, D. Mangelsdorf
2001Science2,144 citations Open access
Semantic Scholar
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.
T. Inagaki, Mihwa Choi, A. Moschetta, Li Peng +10 more
2005Cell Metabolism1,864 citations Open access
Semantic Scholar
Role of LXRs in control of lipogenesis.
J. Schultz, H. Tu, Alvin Luk, J. Repa +8 more
2000Genes & Development1,739 citations Open access
Semantic Scholar
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
J. Repa, G. Liang, J. Ou, Y. Bashmakov +6 more
20001,594 citations Open access
Semantic Scholar
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.
Timothy T. Lu, M. Makishima, J. Repa, K. Schoonjans +3 more
2000Molecules and Cells1,514 citations Open access
Semantic Scholar
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers.
J. Repa, S. Turley, J. Lobaccaro, J. Medina +6 more
2000Science1,380 citations
Semantic Scholar
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.
T. Inagaki, A. Moschetta, Youn-Kyoung Lee, Li Peng +8 more
2006Proceedings of the National Academy of Sciences of the United States of America1,139 citations
Semantic Scholar
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta.
J. Repa, G. Liang, J. Ou, Y. Bashmakov +6 more
2000Genes & Development824 citations
Semantic Scholar
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis.
J. Repa, D. Mangelsdorf
2000Annual Review of Cell and Developmental Biology796 citations
Semantic Scholar
Regulation of ATP-binding Cassette Sterol Transporters ABCG5 and ABCG8 by the Liver X Receptors α and β*
J. Repa, K. Berge, Chris Pomajzl, J. Richardson +2 more
2002Journal of Biological Chemistry752 citations Open access
Semantic Scholar
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes.
B. Laffitte, J. Repa, S. Joseph, Damien C. Wilpitz +3 more
2001Proceedings of the National Academy of Sciences of the United States of America698 citations Open access
Semantic Scholar
The power of real-time PCR.
Mark A. Valasek, J. Repa
2005Advances in Physiology Education659 citations
Semantic Scholar
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis.
K. Uyeda, J. Repa
2006Cell Metabolism523 citations Open access
Semantic Scholar
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
J. Repa, K. Berge, Chris Pomajzl, J. Richardson +2 more
2002Journal of Biological Chemistry436 citations
Semantic Scholar
Human White/Murine ABC8 mRNA Levels Are Highly Induced in Lipid-loaded Macrophages
Asha Venkateswaran, J. Repa, J. Lobaccaro, A. Bronson +2 more
2000Journal of Biological Chemistry406 citations Open access
Semantic Scholar
The liver X receptor gene team: Potential new players in atherosclerosis
J. Repa, D. Mangelsdorf
2002Nature Medicine400 citations
Semantic Scholar
Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1−/− mouse
Benny Liu, S. Turley, Dennis K. Burns, Anna M. Miller +2 more
2009Proceedings of the National Academy of Sciences of the United States of America392 citations Open access
Semantic Scholar
Orphan Nuclear Receptors as eLiXiRs and FiXeRs of Sterol Metabolism*
Timothy T. Lu, J. Repa, D. Mangelsdorf
2001Journal of Biological Chemistry387 citations Open access
Semantic Scholar
The Liver X Receptor (LXR) and Hepatic Lipogenesis
Ji-Young Cha, J. Repa
2007Journal of Biological Chemistry298 citations Open access
Semantic Scholar
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
T. Claudel, M. D. Leibowitz, C. Fiévet, A. Tailleux +8 more
2001Proceedings of the National Academy of Sciences of the United States of America294 citations Open access
Semantic Scholar
Regulation of Lipoprotein Lipase by the Oxysterol Receptors, LXRα and LXRβ*
Yuan Zhang, J. Repa, K. Gauthier, D. Mangelsdorf
2001Journal of Biological Chemistry282 citations Open access
Semantic Scholar
DGAT1 Is Not Essential for Intestinal Triacylglycerol Absorption or Chylomicron Synthesis*
K. Buhman, Steven J. Smith, S. Stone, J. Repa +6 more
2002Journal of Biological Chemistry243 citations Open access
Semantic Scholar
Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver
Y. Wan, Dahsing An, Yan Cai, J. Repa +9 more
2000Molecular and Cellular Biology232 citations Open access
Semantic Scholar
Expression of ABCG5 and ABCG8 Is Required for Regulation of Biliary Cholesterol Secretion*
Liqing Yu, S. Gupta, Fang Xu, Amy D. B. Liverman +5 more
2005Journal of Biological Chemistry228 citations Open access
Semantic Scholar
Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C
Ting-Ting Chu, Xintao Tu, Kun Yang, Jianjun Wu +2 more
2021Nature213 citations Open access
Semantic Scholar
THE LIVER X RECEPTOR AND HEPATIC LIPOGENESIS: THE CARBOHYDRATE-RESPONSE ELEMENT BINDING PROTEIN IS A TARGET GENE OF LXR
Ji-Young Cha, J. Repa
2006210 citations
Semantic Scholar
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
B. Goodwin, K. Gauthier, M. Umetani, M. Watson +6 more
2002Proceedings of the National Academy of Sciences of the United States of America205 citations Open access
Semantic Scholar
Nuclear receptor regulation of cholesterol and bile acid metabolism.
J. Repa, D. Mangelsdorf
1999Current Opinion in Biotechnology194 citations
Semantic Scholar
Disruption of the Sterol 27-Hydroxylase Gene in Mice Results in Hepatomegaly and Hypertriglyceridemia
J. Repa, E. Lund, J. Horton, E. Leitersdorf +3 more
2000Journal of Biological Chemistry192 citations Open access
Semantic Scholar
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
N. Gustavsson, Ye Lao, A. Maximov, J. Chuang +6 more
2008Proceedings of the National Academy of Sciences of the United States of America181 citations Open access
Semantic Scholar
HDAC9 represses cholesterol efflux and generation of alternatively activated macrophages in atherosclerosis development
Q. Cao, Shun-Xing Rong, J. Repa, R. S. St. Clair +2 more
2014Arteriosclerosis, Thrombosis and Vascular Biology177 citations Open access
Semantic Scholar
The Phospholipid Transfer Protein Gene Is a Liver X Receptor Target Expressed by Macrophages in Atherosclerotic Lesions
B. Laffitte, S. Joseph, Mingyi Chen, A. Castrillo +4 more
2003Molecular and Cellular Biology173 citations Open access
Semantic Scholar
Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid
Benny Liu, Charina M Ramirez, Anna M. Miller, J. Repa +2 more
2010Journal of Lipid Research170 citations Open access
Semantic Scholar
Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life
Charina M Ramirez, Benny Liu, Anna M. Taylor, J. Repa +4 more
2010Pediatric Research159 citations Open access
Semantic Scholar
Differential regulation and properties of angiopoietin-like proteins 3 and 4 Published, JLR Papers in Press, May 1, 2005. DOI 10.1194/jlr.M500005-JLR200
Hongfei Ge, Ji-Young Cha, Harini Gopal, Christopher T. Harp +3 more
2005Journal of Lipid Research158 citations Open access
Semantic Scholar
Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 Mouse
J. Repa, Hao Li, T. Frank-Cannon, Mark A. Valasek +3 more
2007Journal of Neuroscience150 citations Open access
Semantic Scholar
Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function.
M. Hinshelwood, J. Repa, J. Shelton, J. Richardson +2 more
2003Molecular and Cellular Endocrinology148 citations
Semantic Scholar
Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and is Prevented by Driving Cholesterol Export from this Compartment
A. Aqul, Benny Liu, Charina M Ramirez, A. Pieper +6 more
2011Journal of Neuroscience147 citations Open access
Semantic Scholar
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism
Zhiguang Huang, Menglu Zhang, Abigail A. Plec, S. Estill +4 more
2018Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.
Y. Zhang, J. Repa, K. Gauthier, D. Mangelsdorf
2001Journal of Biological Chemistry130 citations
Semantic Scholar
Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells.
J. Chuang, Ichiro Sakata, Daisuke Kohno, M. Perelló +3 more
2011Molecular Endocrinology128 citations Open access
Semantic Scholar
Chronic social defeat stress disrupts regulation of lipid synthesis[S]
J. Chuang, Hu-Xing Cui, B. Mason, Melissa Mahgoub +7 more
2010Journal of Lipid Research123 citations Open access
Semantic Scholar
ACAT2 deficiency limits cholesterol absorption in the cholesterol‐fed mouse: Impact on hepatic cholesterol homeostasis
J. Repa, K. Buhman, Robert V Farese, J. Dietschy +1 more
2004Hepatology121 citations
Semantic Scholar
Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease.
Hao Li, J. Repa, Mark A. Valasek, E. Beltroy +3 more
2005Journal of Neuropathology and Experimental Neurology119 citations Open access
Semantic Scholar
Fenofibrate reduces intestinal cholesterol absorption via PPARalpha-dependent modulation of NPC1L1 expression in mouse.
Mark A. Valasek, S. Clarke, J. Repa
2007Journal of Lipid Research111 citations Open access
Semantic Scholar
Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse
Ryan D. Jones, Anna M. Taylor, Ernest Y. Tong, J. Repa
2013Drug Metabolism And Disposition106 citations Open access
Semantic Scholar
All-trans-retinol is a ligand for the retinoic acid receptors.
J. Repa, Kristine K. Hanson, M. Clagett-Dame
1993Proceedings of the National Academy of Sciences of the United States of America99 citations Open access
Semantic Scholar
Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400475-JLR200
J. Repa, S. Turley, G. Quan, J. Dietschy
2005Journal of Lipid Research95 citations Open access
Semantic Scholar
Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200144-JLR200
J. Repa, J. Dietschy, S. Turley
2002Journal of Lipid Research88 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Mangelsdorf×25
Invite
D. Mangelsdorf — researcher profile on SciRah
S. Turley×11
Invite
S. Turley — researcher profile on SciRah
J. Dietschy×11
Invite
J. Dietschy — researcher profile on SciRah
B. Shan×5
Invite
B. Shan — researcher profile on SciRah

×5

Invite

J. Richardson — researcher profile on SciRah

Mark A. Valasek×4

Invite

Mark A. Valasek — researcher profile on SciRah

Invite

Benny Liu — researcher profile on SciRah

A. Moschetta×3

Invite

A. Moschetta — researcher profile on SciRah

Invite

S. Kliewer — researcher profile on SciRah

J. Lobaccaro×3

Invite

J. Lobaccaro — researcher profile on SciRah

Invite

H. Hobbs — researcher profile on SciRah

Ji-Young Cha×3

Invite

Ji-Young Cha — researcher profile on SciRah