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Andreas Rothfuss · SciRah

Researcher profile · Semantic Scholar

Andreas Rothfuss

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Andreas Rothfuss — researcher profile on SciRah

h-index: 22
Works: 31
Citations: 1,841

Most-cited papers

Repair Kinetics of Genomic Interstrand DNA Cross-Links: Evidence for DNA Double-Strand Break-Dependent Activation of the Fanconi Anemia/BRCA Pathway
Andreas Rothfuss, M. Grompe
2004Molecular and Cellular Biology234 citations Open access
Semantic Scholar
Induced micronucleus frequencies in peripheral lymphocytes as a screening test for carriers of a BRCA1 mutation in breast cancer families.
Andreas Rothfuss, Petra Schütz, Sylvia Bochum, T. Volm +4 more
2000Cancer Research218 citations
Semantic Scholar
The comet assay: a sensitive genotoxicity test for the detection of DNA damage and repair.
G. Speit, Andreas Rothfuss
2012Methods in molecular biology114 citations
Semantic Scholar
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Andreas Rothfuss, M. O'Donovan, M. De Boeck, D. Brault +18 more
2010Mutation research102 citations
Semantic Scholar
Genotoxicity of hyperbaric oxygen.
G. Speit, Claudia Dennog, P. Radermacher, Andreas Rothfuss
2002Mutation research98 citations
Semantic Scholar
Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
S. Pfuhler, D. Kirkland, P. Kasper, M. Hayashi +13 more
2009Mutation research93 citations
Semantic Scholar
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Andreas Rothfuss, Masamitu Honma, A. Czich, M. Aardema +14 more
2011Mutation research92 citations
Semantic Scholar
Use of computer-assisted prediction of toxic effects of chemical substances.
B. Simon-Hettich, Andreas Rothfuss, T. Steger-Hartmann
2006Toxicology89 citations
Semantic Scholar
Adaptive protection against the induction of oxidative DNA damage after hyperbaric oxygen treatment.
Andreas Rothfuss, Claudia Dennog, G. Speit
1998Carcinogenesis77 citations Open access
Semantic Scholar
Involvement of heme oxygenase-1 (HO-1) in the adaptive protection of human lymphocytes after hyperbaric oxygen (HBO) treatment.
Andreas Rothfuss, P. Radermacher, G. Speit
2001Carcinogenesis76 citations Open access
Semantic Scholar
Mutagen sensitivity of peripheral blood from women carrying a BRCA1 or BRCA2 mutation.
K. Trenz, Andreas Rothfuss, Petra Schütz, G. Speit
2002Mutation research72 citations
Semantic Scholar
Loss of p21 Permits Carcinogenesis from Chronically Damaged Liver and Kidney Epithelial Cells Despite Unchecked Apoptosis
H. Willenbring, A. Sharma, A. Vogel, Andrew Y. Lee +4 more
2008Cancer Cell65 citations Open access
Semantic Scholar
Safety pharmacology--current and emerging concepts.
Junnat M. Hamdam, S. Sethu, Trevor Smith, A. Alfirevic +26 more
2013Toxicology and Applied Pharmacology55 citations
Semantic Scholar
Investigations on the mechanism of hyperbaric oxygen (HBO)-induced adaptive protection against oxidative stress.
Andreas Rothfuss, G. Speit
2002Mutation research54 citations
Semantic Scholar
Response to X-Irradiation of Fanconi Anemia Homozygous and Heterozygous Cells Assessed by the Single-Cell Gel Electrophoresis (Comet) Assay
Cholpon S. Djuzenova, Andreas Rothfuss, U. Oppitz, G. Speit +3 more
2001Laboratory Investigation50 citations Open access
Semantic Scholar
Towards the creation of an international toxicology information centre.
P. Judson, Paul A. Cooke, N. Doerrer, N. Greene +12 more
2005Toxicology48 citations
Semantic Scholar
The influence of temperature during alkaline treatment and electrophoresis on results obtained with the comet assay.
G. Speit, K. Trenz, Petra Schütz, Andreas Rothfuss +1 more
1999Toxicology Letters46 citations
Semantic Scholar
Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia
S. Sewing, A. Roth, M. Winter, A. Dieckmann +9 more
2017PLoS ONE45 citations Open access
Semantic Scholar
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
Joerg F. Hipp, F. Knoflach, R. Comley, T. Ballard +16 more
2021Scientific Reports41 citations Open access
Semantic Scholar
Evaluation of mutagenic effects of hyperbaric oxygen (HBO) in vitro. II. Induction of oxidative DNA damage and mutations in the mouse lymphoma assay.
Andreas Rothfuss, O. Merk, P. Radermacher, G. Speit
2000Mutation research40 citations
Semantic Scholar
Evaluation of mutagenic effects of hyperbaric oxygen (HBO) in vitro
Andreas Rothfuss, W. Stahl, P. Radermacher, G. Speit
1999Environmental and Molecular Mutagenesis35 citations
Semantic Scholar
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation.
H. Prior, P. Baldrick, S. Beken, H. Booler +36 more
2020Regulatory toxicology and pharmacology : RTP34 citations Open access
Semantic Scholar
Computational prediction of the chromosome-damaging potential of chemicals.
Andreas Rothfuss, T. Steger-Hartmann, N. Heinrich, J. Wichard
2006Chemical Research in Toxicology21 citations
Semantic Scholar
Overexpression of heme oxygenase‐1 (HO‐1) in V79 cells results in increased resistance to hyperbaric oxygen (HBO)‐induced DNA damage
Andreas Rothfuss, G. Speit
2002Environmental and Molecular Mutagenesis21 citations
Semantic Scholar
Perspectives of data science in preclinical safety assessment.
T. Steger-Hartmann, A. Kreuchwig, Ken Wang, Fabian Birzele +3 more
2023Drug Discovery Today11 citations
Semantic Scholar
Oxygenated water does not induce genotoxic effects in the comet assay.
G. Speit, Petra Schütz, K. Trenz, Andreas Rothfuss
2002Toxicology Letters10 citations
Semantic Scholar
Safety pharmacology — Current and emerging concepts D P R O O F
Junnat M. Hamdam, S. Sethu, Trevor Smith, Ana Al +27 more
20131 citations
Semantic Scholar
Preclinical and Clinical Pharmacology of Basmisanil, a Novel Selective GABAA-α5 Receptor Negative Allosteric Modulator
Joerg F. Hipp, F. Knoflach, R. Comley, T. Ballard +15 more
20200 citations Open access
Semantic Scholar
A Framework Proposal to Follow‐Up on Preclinical Convulsive Signals of a New Molecular Entity in First‐in‐Human Studies Using Electroencephalographic Monitoring
M. Abt, T. Dinklo, Andreas Rothfuss, E. Husar +5 more
2019Clinical pharmacology and therapy0 citations Open access
Semantic Scholar
Chapter 5. Cytogenetic Parameters
G. Obe, H. Fender, G. Wolf, E. Gebhart +5 more
20080 citations
Semantic Scholar
[abstract] HBO AND DNA DAMAGE - NEW INSIGHTS INTO WHETHER HBO MAY PROMOTE CANCER.
Andreas Rothfuss, P. Radermacher, G. Speit
20000 citations
Semantic Scholar

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