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H. Willenbring · SciRah

Researcher profile · Semantic Scholar

H. Willenbring

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H. Willenbring — researcher profile on SciRah

h-index: 37
Works: 69
Citations: 7,975

Most-cited papers

Cell fusion is the principal source of bone-marrow-derived hepatocytes
Xin Wang, H. Willenbring, Y. Akkari, Yumi Torimaru +6 more
2003Nature1,647 citations
Semantic Scholar
A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice
C. Mitchell, H. Willenbring
2008Nature Protocols570 citations
Semantic Scholar
Cholangiocarcinomas can originate from hepatocytes in mice.
B. Fan, Y. Malato, D. Calvisi, Syed Naqvi +7 more
2012Journal of Clinical Investigation471 citations Open access
Semantic Scholar
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
Y. Malato, Syed Naqvi, Nina Schürmann, R. Ng +5 more
2011Journal of Clinical Investigation429 citations Open access
Semantic Scholar
Myelomonocytic cells are sufficient for therapeutic cell fusion in liver
H. Willenbring, A. S. Bailey, M. Foster, Y. Akkari +5 more
2004Nature Medicine405 citations
Semantic Scholar
On the origin of the term "stem cell".
M. Ramalho-Santos, H. Willenbring
2007Cell Stem Cell300 citations Open access
Semantic Scholar
Bone marrow-derived cells fuse with normal and transformed intestinal stem cells.
Adnan Z. Rizvi, John R. Swain, Paige S. Davies, A. S. Bailey +5 more
2006Proceedings of the National Academy of Sciences of the United States of America272 citations Open access
Semantic Scholar
Mouse liver repopulation with hepatocytes generated from human fibroblasts
Sai-Yong Zhu, M. Rezvani, J. Harbell, Aras N. Mattis +4 more
2014Nature261 citations Open access
Semantic Scholar
De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation
J. Schaub, Kari A. Huppert, Simone N. T. Kurial, Bernadette Y. Hsu +11 more
2018Nature259 citations Open access
Semantic Scholar
Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury
J. Schaub, Y. Malato, Coralie Gormond, H. Willenbring
2014Cell Reports258 citations Open access
Semantic Scholar
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
L. Saunders, A. Sharma, Jaime Tawney, M. Nakagawa +4 more
2010Aging247 citations Open access
Semantic Scholar
MicroRNAs Control Hepatocyte Proliferation During Liver Regeneration
Guisheng Song, A. Sharma, Garrett R. Roll, R. Ng +4 more
2010Hepatology214 citations Open access
Semantic Scholar
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.
Silvia Espejel, Garrett R. Roll, K. McLaughlin, Andrew Y. Lee +5 more
2010Journal of Clinical Investigation197 citations Open access
Semantic Scholar
Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration
Feng Chen, R. J. Jimenez, Khushbu Sharma, H. Luu +4 more
2019Cell Stem Cell194 citations Open access
Semantic Scholar
Myeloid lineage progenitors give rise to vascular endothelium
A. S. Bailey, H. Willenbring, Shuguang Jiang, Daniel A. Anderson +4 more
2006Proceedings of the National Academy of Sciences of the United States of America194 citations Open access
Semantic Scholar
Physiological Ranges of Matrix Rigidity Modulate Primary Mouse Hepatocyte Function In Part Through Hepatocyte Nuclear Factor 4 Alpha
S. Desai, Jason C. Tung, Vivian X. Zhou, James P. Grenert +6 more
2016Hepatology173 citations Open access
Semantic Scholar
Inhibition of MicroRNA-24 Expression in Liver Prevents Hepatic Lipid Accumulation and Hyperlipidemia
R. Ng, Heng Wu, Hong Xiao, Xin Chen +3 more
2014Hepatology163 citations Open access
Semantic Scholar
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration.
R. Ng, Guisheng Song, G. Roll, Niels M. Frandsen +1 more
2012Journal of Clinical Investigation161 citations Open access
Semantic Scholar
MiR-494 Within an Oncogenic MicroRNA Megacluster Regulates G1/S Transition in Liver Tumorigenesis Through Suppression of MCC
L. Lim, A. Balakrishnan, N. Huskey, K. Jones +12 more
2013Hepatology115 citations Open access
Semantic Scholar
Stem Cells in Liver Diseases and Cancer: Recent Advances on the Path to New Therapies
C. Rountree, L. Mishra, H. Willenbring
2012Hepatology105 citations Open access
Semantic Scholar
Highly Efficient Differentiation of Functional Hepatocytes From Human Induced Pluripotent Stem Cells
Xiaocui Ma, Yu-You Duan, Benjamin Tschudy-Seney, G. Roll +9 more
2013Stem Cells Translational Medicine89 citations Open access
Semantic Scholar
Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration
Ian Huck, S. Gunewardena, Regina Español‐Suñer, H. Willenbring +1 more
2019Hepatology84 citations Open access
Semantic Scholar
Genomic structure and transcript variants of the human methylenetetrahydrofolate reductase gene
A. Homberger, M. Linnebank, C. Winter, H. Willenbring +3 more
2000European Journal of Human Genetics73 citations
Semantic Scholar
In vivo genetic selection of renal proximal tubules.
P. Held, M. Al‐Dhalimy, H. Willenbring, Y. Akkari +6 more
2006Molecular Therapy70 citations Open access
Semantic Scholar
Telomerase activity in human proliferative breast lesions.
C. Poremba, W. Böcker, H. Willenbring, K. Schäfer +4 more
1998International Journal of Oncology68 citations
Semantic Scholar
Loss of p21 Permits Carcinogenesis from Chronically Damaged Liver and Kidney Epithelial Cells Despite Unchecked Apoptosis
H. Willenbring, A. Sharma, A. Vogel, Andrew Y. Lee +4 more
2008Cancer Cell65 citations Open access
Semantic Scholar
A Screen in Mice Uncovers Repression of Lipoprotein Lipase by MicroRNA-29a as a Mechanism for Lipid Distribution Away From the Liver
Aras N. Mattis, Guisheng Song, Kelly Hitchner, Roy Y. Kim +11 more
2014Hepatology63 citations Open access
Semantic Scholar
Telomerase activity distinguishes between neuroblastomas with poor prognosis
C. Poremba, H. Willenbring, B. Hero, H. Christiansen +5 more
199959 citations Open access
Semantic Scholar
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development
Anurag Mathur, Peter Loskill, SoonGweon Hong, Jae Young Lee +6 more
2013Stem cell research & therapeutics56 citations Open access
Semantic Scholar
Assessing the Therapeutic Potential of Lab-Made Hepatocytes
M. Rezvani, A. Grimm, H. Willenbring
2016Hepatology53 citations Open access
Semantic Scholar
Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction
Felipe T. Lee-Montiel, Alexander Laemmle, V. Charwat, L. Dumont +10 more
2021Frontiers in Pharmacology44 citations Open access
Semantic Scholar
Molecular genetic analysis and human chorionic gonadotropin stimulation tests in the diagnosis of prepubertal patients with partial 5α-reductase deficiency
O. Hiort, H. Willenbring, N. Albers, W. Hecker +3 more
1996European Journal of Pediatrics43 citations
Semantic Scholar
Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages
Marko Groeger, Koji Matsuo, Emad Heidaryarash, Ashley Pereira +6 more
2023Nature Communications42 citations Open access
Semantic Scholar
Argininosuccinate lyase (ASL) deficiency: mutation analysis in 27 patients and a completed structure of the human ASL gene
M. Linnebank, E. Tschiedel, J. Häberle, A. Linnebank +3 more
2002Human Genetics41 citations
Semantic Scholar
Nonisotopic single strand conformation analysis of the 5 alpha-reductase type 2 gene for the diagnosis of 5 alpha-reductase deficiency.
O. Hiort, G. Sinnecker, H. Willenbring, A. Lehners +2 more
1996Journal of Clinical Endocrinology and Metabolism39 citations
Semantic Scholar
Telomerase activity distinguishes between neuroblastomas with good and poor prognosis.
C. Poremba, H. Willenbring, B. Hero, H. Christiansen +5 more
1999Annals of Oncology38 citations
Semantic Scholar
Therapeutic liver reconstitution with murine cells isolated long after death
Laura R. Erker, H. Azuma, Andrew Y. Lee, Chang-Sheng Guo +7 more
2010Gastroenterology37 citations Open access
Semantic Scholar
Core promoter recognition complex changes accompany liver development
J. D'Alessio, R. Ng, H. Willenbring, R. Tjian
2011Proceedings of the National Academy of Sciences of the United States of America33 citations Open access
Semantic Scholar
Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases.
A. Vogel, J. Aslan, H. Willenbring, C. Klein +4 more
2006Gastroenterology32 citations Open access
Semantic Scholar
Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration
S. Eckardt, K. McLaughlin, H. Willenbring
2011Cell Cycle31 citations Open access
Semantic Scholar
Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice
C. Mitchell, H. Willenbring
2014Nature Protocols27 citations Open access
Semantic Scholar
iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile
Caroline C. Duwaerts, D. Le Guillou, C. Her, Nathaniel J. Phillips +3 more
2021Gastroenterology26 citations Open access
Semantic Scholar
AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites.
Franziska Hentzschel, Christiane Hammerschmidt-Kamper, Kathleen Börner, K. Heiss +9 more
2014Molecular Therapy26 citations Open access
Semantic Scholar
Human iPSC-derived proinflammatory macrophages cause insulin resistance in an isogenic white adipose tissue microphysiological system
Lin Qi, Koji Matsuo, Ashley Pereira, Yue-Tung Lee +8 more
2023Small23 citations Open access
Semantic Scholar
Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation
Silvia Espejel, S. Eckardt, J. Harbell, Garrett R. Roll +2 more
2014Stem Cells20 citations Open access
Semantic Scholar
Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency
Alexander Laemmle, M. Poms, Bernadette Y. Hsu, Mariia Borsuk +6 more
2021Hepatology19 citations Open access
Semantic Scholar
Delineating the Hepatocyte's Hematopoietic Fusion Partner
H. Willenbring, M. Grompe
2004Cell Cycle19 citations Open access
Semantic Scholar
Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference.
G. Abou-Alfa, J. Andersen, W. Chapman, M. Choti +23 more
2016Journal of Gastrointestinal Oncology18 citations Open access
Semantic Scholar
Transplantable Liver Organoids Made From Only Three Ingredients
H. Willenbring, A. Soto-Gutierrez
2013Cell Stem Cell16 citations Open access
Semantic Scholar
A simple code for installing hepatocyte function.
H. Willenbring
2011Cell Stem Cell14 citations Open access
Semantic Scholar

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