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F. Genze · SciRah

Researcher profile · Semantic Scholar

F. Genze

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F. Genze — researcher profile on SciRah

h-index: 25
Works: 51
Citations: 2,209

Most-cited papers

PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation
N. Azoitei, Alexander Becher, K. Steinestel, A. Rouhi +4 more
2016Molecular Cancer306 citations Open access
Semantic Scholar
Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo.
M. Vogler, H. Walczak, Dominic Stadel, T. Haas +6 more
2008Cancer Research163 citations
Semantic Scholar
Activation of Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Is Required for Glial Cell Line-Derived Neurotrophic Factor-Induced Migration and Invasion of Pancreatic Carcinoma Cells
C. Veit, F. Genze, A. Menke, Silke Hoeffert +3 more
2004Cancer Research154 citations
Semantic Scholar
Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.
M. Vogler, H. Walczak, Dominic Stadel, T. Haas +9 more
2009Cancer Research153 citations Open access
Semantic Scholar
Antiinflammatory and Antiatherogenic Effects of the NF-&kgr;B Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE−/− Mice
Clarisse Cuaz-Pérolin, L. Billiet, E. Baugé, C. Copin +6 more
2007143 citations Open access
Semantic Scholar
Methylene blue mediated photodynamic therapy in experimental colorectal tumors in mice.
Klaus Orth, G. Beck, F. Genze, A. Rück
2000Journal of Photochemistry and Photobiology. B: Biology117 citations
Semantic Scholar
Thioredoxin-1 Promotes Anti-Inflammatory Macrophages of the M2 Phenotype and Antagonizes Atherosclerosis
K. El Hadri, Dler Faieeq Darweesh Mahmood, D. Couchie, I. Jguirim-Souissi +6 more
2012Arteriosclerosis, Thrombosis and Vascular Biology111 citations Open access
Semantic Scholar
Chorioallantoic membrane assay: vascularized 3-dimensional cell culture system for human prostate cancer cells as an animal substitute model.
K. Kunzi-Rapp, F. Genze, R. Küfer, E. Reich +2 more
2001Journal of Urology97 citations
Semantic Scholar
Antiinflammatory and antiatherogenic effects of the NF-kappaB inhibitor acetyl-11-keto-beta-boswellic acid in LPS-challenged ApoE-/- mice.
Clarisse Cuaz-Pérolin, L. Billiet, E. Baugé, C. Copin +6 more
2008Arteriosclerosis, Thrombosis and Vascular Biology80 citations
Semantic Scholar
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours
N. Azoitei, G. Pusapati, A. Kleger, P. Möller +7 more
2010Gut79 citations
Semantic Scholar
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33
N. Azoitei, Christopher M. Hoffmann, J. Ellegast, C. Ball +12 more
2012Journal of Experimental Medicine72 citations Open access
Semantic Scholar
Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells
M. Hofer, A. Menke, F. Genze, P. Gierschik +1 more
2004British Journal of Cancer67 citations Open access
Semantic Scholar
Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38.
Ute Dreissigacker, M. S. Mueller, Monika Unger, P. Siegert +3 more
2006Cellular Signalling58 citations
Semantic Scholar
HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
N. Azoitei, Kristina Diepold, C. Brunner, A. Rouhi +9 more
2014Cancer Research54 citations Open access
Semantic Scholar
Plasmin Triggers Chemotaxis of Monocyte-Derived Dendritic Cells Through an Akt2-Dependent Pathway and Promotes a T-Helper Type-1 Response
Xuehua Li, T. Syrovets, F. Genze, Kai Pitterle +3 more
2010Arteriosclerosis, Thrombosis and Vascular Biology54 citations Open access
Semantic Scholar
Comparison of In Vitro- and Chorioallantoic Membrane (CAM)-Culture Systems for Cryopreserved Medulla-Contained Human Ovarian Tissue
V. Isachenko, P. Mallmann, A. Petrunkina, G. Rahimi +6 more
2012PLoS ONE53 citations Open access
Semantic Scholar
High‐resolution MRI analysis of breast cancer xenograft on the chick chorioallantoic membrane
Zhi Zuo, T. Syrovets, F. Genze, A. Abaei +3 more
2015NMR in Biomedicine42 citations
Semantic Scholar
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.
N. Azoitei, A. Kleger, N. Schoo, D. Thal +11 more
2011Neuro-Oncology41 citations Open access
Semantic Scholar
Inhibition of clonogenic tumor growth: a novel function of Smac contributing to its antitumor activity
M. Vogler, Stavros Giagkousiklidis, F. Genze, J. Gschwend +2 more
2005Oncogene40 citations Open access
Semantic Scholar
Active targeting of mesoporous silica drug carriers enhances γ-secretase inhibitor efficacy in an in vivo model for breast cancer.
R. Wittig, J. Rosenholm, E. von Haartman, J. Hemming +5 more
2014Nanomedicine38 citations
Semantic Scholar
Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness.
L. Perkhofer, K. Walter, I. Costa, M. C. Romero Carrasco +16 more
2016Stem Cell Research33 citations Open access
Semantic Scholar
Inhibition of Glycogen Synthase Kinase-3β Counteracts Ligand-Independent Activity of the Androgen Receptor in Castration Resistant Prostate Cancer
Stefanie V. Schütz, A. Schrader, F. Zengerling, F. Genze +2 more
2011PLoS ONE33 citations Open access
Semantic Scholar
Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity
K. Dietrich, Rene Schwarz, M. Liška, Stefanie Grass +6 more
2009Biological chemistry32 citations
Semantic Scholar
Stilbene Induced Inhibition of Androgen Receptor Dimerization: Implications for AR and ARΔLBD-Signalling in Human Prostate Cancer Cells
W. Streicher, Manuel Luedeke, A. Azoitei, F. Zengerling +5 more
2014PLoS ONE31 citations Open access
Semantic Scholar
The zinc-finger protein KCMF1 is overexpressed during pancreatic cancer development and downregulation of KCMF1 inhibits pancreatic cancer development in mice
S. Beilke, Franz Oswald, F. Genze, Thomas Wirth +2 more
2010Oncogene30 citations Open access
Semantic Scholar
High-performance liquid chromatographic determination of acetyl-11-keto-α-boswellic acid, a novel pentacyclic triterpenoid, in plasma using a fluorinated stationary phase and photodiode array detection : Application in pharmacokinetic studies
B. Büchele, Waltraud Zugmaier, F. Genze, T. Simmet
200524 citations
Semantic Scholar
Baseline MAPK signaling activity confers intrinsic radioresistance to KRAS-mutant colorectal carcinoma cells by rapid upregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K).
S. Eder, Annette Arndt, A. Lamkowski, Wassiliki Daskalaki +6 more
2017Cancer Letters20 citations
Semantic Scholar
Antagonistic effects of sodium butyrate and N-(4-hydroxyphenyl)-retinamide on prostate cancer.
R. Kuefer, F. Genze, Waltraud Zugmaier, R. Hautmann +5 more
2007Neoplasia20 citations Open access
Semantic Scholar
Characterization of 3alpha-acetyl-11-keto-alpha-boswellic acid, a pentacyclic triterpenoid inducing apoptosis in vitro and in vivo.
B. Büchele, Waltraud Zugmaier, A. Estrada, F. Genze +4 more
2006Planta Medica16 citations
Semantic Scholar
The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells
K. Steinestel, S. Eder, Konstantin Ehinger, J. Schneider +5 more
2016Tumor Biology12 citations
Semantic Scholar
A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells
Martin Müller, Jana Schröer, N. Azoitei, T. Eiseler +10 more
2015Scientific Reports9 citations Open access
Semantic Scholar
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
Torsten Diesinger, A. Lautwein, Sebastian Bergler, D. Buckert +17 more
2021Canadian Journal of Gastroenterology and Hepatology8 citations Open access
Semantic Scholar
Photodynamic activity of liposome‐delivered Cd‐texaphyrin using tumor‐bearing nude mice
K. König, F. Genze, Kurt Miller, A. Rück +2 more
1993Lasers in Surgery and Medicine6 citations
Semantic Scholar
68Ga-DOTA-DUPA-Pep as a new peptide conjugate for molecular imaging of prostate carcinoma
Gordon Winter, B. Zlatopolskiy, T. Kull, Jens Bertram +4 more
20113 citations
Semantic Scholar
High-performance liquid chromatographic determination of acetyl-11-keto-alpha-boswellic acid, a novel pentacyclic triterpenoid, in plasma using a fluorinated stationary phase and photodiode array detection: application in pharmacokinetic studies.
B. Büchele, Waltraud Zugmaier, F. Genze, T. Simmet
2005Journal of chromatography. B, Analytical technologies in the biomedical and life sciences3 citations
Semantic Scholar
Confocal observation of hydrophilic and lipophilic photosensitizers in endothelial cells, lumen of the vessels, interstitium, and tumor cells using the chicken chorioallantoic membrane
A. Rueck, N. Akguen, K. Heckelsmiller, G. Beck +2 more
1998Biomedical optics3 citations
Semantic Scholar
Photodynamic therapy of experimental colonic tumours with 5-aminolevulinic-acid-induced endogenous porphyrins
K. Orth, K. König, F. Genze, A. Rück
2005Journal of Cancer Research and Clinical Oncology2 citations Open access
Semantic Scholar
Mechanism of cell destruction and cell protection during methylene-blue-induced PDT
A. Rueck, G. Beck, K. Heckelsmiller, U. Knoedlsdorfer +2 more
1999European Conference on Biomedical Optics2 citations
Semantic Scholar
Laser-induced fluorescence spectroscopy of AlPc4 and liposomal ZnPc in a rat bladder tumor model and correlation with PDT efficiency
N. J. Edinak, A. Rueck, R. Steiner, F. Genze +1 more
1996European Conference on Biomedical Optics1 citations
Semantic Scholar
Erratum to: The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells
K. Steinestel, S. Eder, Konstantin Ehinger, J. Schneider +5 more
2015Tumor Biology0 citations Open access
Semantic Scholar
Protein kinase D2 modulates tumor growth and tumor angiogenic programme induced by heat shock protein 90
N. Azoitei, Kristina Diepold, S. Brobovich, C. Brunner +9 more
20140 citations
Semantic Scholar
Abstract 5129: Role of PRKD2 in HSP90 inhibition-mediated suppression of cancer growth
N. Azoitei, Kristina Diepold, F. Genze, A. Rouhi +8 more
20140 citations
Semantic Scholar
Time-restricted activation of Protein Kinase D2 directs vasculogenesis during mouse embryonic stem cell differentiation
Martin Müller, J. Schroeer, N. Azoitei, F. Genze +4 more
20140 citations
Semantic Scholar
Role of Protein Kinase D2 (PKD2) in Lymphangiogenesis
Alexander Becher, A. Staab, F. Genze, Susanne Bobrovich +2 more
20130 citations
Semantic Scholar
Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction
L. Marck, Garima Jain, M. Cronauer, F. Genze +1 more
20130 citations
Semantic Scholar
Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33
N. Azoitei, Christopher M. Hoffmann, J. Ellegast, C. Ball +12 more
20120 citations
Semantic Scholar
Regulation of Protein kinase D2 by Hsp is crucial for tumour cell-endothelial cell communication in gastrointestinal tumours
N. Azoitei, G. Pusapati, A. Kleger, P. Mueller +7 more
20120 citations
Semantic Scholar
Role of Protein kinase D2 in pancreatic tumor growth and tumor angiogenesis
N. Azoitei, G. Pusapati, A. Kleger, C. Brunner +4 more
20090 citations
Semantic Scholar
Plasmin is a chemoattractant for immature dendritic cells acting through Akt2‐dependent mechanisms
T. Syrovets, Xuehua Li, F. Genze, Kai Pitterle +1 more
20090 citations
Semantic Scholar
260 POSTER A novel paradigm for apoptosis-based therapy of pancreatic cancer: sensitizer/inducer concept of XIAP inhibitors combined with TRAIL
M. Vogler, H. Walczak, Dominic Stadel, F. Genze +4 more
20080 citations
Semantic Scholar

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T. Simmet — researcher profile on SciRah
N. Azoitei×13
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A. Kleger — researcher profile on SciRah

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