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H. Walczak · SciRah

Researcher profile · Semantic Scholar

H. Walczak

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H. Walczak — researcher profile on SciRah

h-index: 93
Works: 270
Citations: 45K

Most-cited papers

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L. Galluzzi, I. Vitale, S. Aaronson, J. Abrams +165 more
2018Cell Death and Differentiation6,079 citations Open access
Semantic Scholar
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
T. V. Berghe, A. Linkermann, S. Jouan-Lanhouet, H. Walczak +1 more
2014Nature reviews. Molecular cell biology1,669 citations
Semantic Scholar
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L. Galluzzi, J. M. Bravo-San Pedro, I. Vitale, S. Aaronson +104 more
2014Cell Death and Differentiation985 citations Open access
Semantic Scholar
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
A. Galleu, Y. Riffo-Vasquez, C. Trento, C. Lomas +17 more
2017Science Translational Medicine602 citations Open access
Semantic Scholar
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
A. Linkermann, J. Bräsen, M. Darding, M. Jin +10 more
2013Proceedings of the National Academy of Sciences of the United States of America541 citations Open access
Semantic Scholar
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy
Silvia von Karstedt, A. Montinaro, H. Walczak
2017Nature Reviews. Cancer517 citations
Semantic Scholar
Getting TRAIL back on track for cancer therapy
J. Lemke, S. von Karstedt, J. Zinngrebe, H. Walczak
2014Cell Death and Differentiation462 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
Onto better TRAILs for cancer treatment
D. de Miguel, J. Lemke, A. Anel, H. Walczak +1 more
2016Cell Death and Differentiation299 citations Open access
Semantic Scholar
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
Peter Draber, S. Kupka, M. Reichert, Helena Dráberová +10 more
2015Cell Reports277 citations Open access
Semantic Scholar
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation
É. Lafont, Peter Draber, E. Rieser, M. Reichert +11 more
2018Nature Cell Biology254 citations Open access
Semantic Scholar
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
J. Rickard, H. Anderton, N. Etemadi, U. Nachbur +19 more
2014eLife253 citations Open access
Semantic Scholar
HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.
N. Peltzer, E. Rieser, L. Taraborrelli, Peter Draber +10 more
2014Cell Reports247 citations Open access
Semantic Scholar
Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency
E. Giampazolias, B. Zunino, S. Dhayade, Florian J. Bock +23 more
2017Nature Cell Biology236 citations Open access
Semantic Scholar
Death receptor-ligand systems in cancer, cell death, and inflammation.
H. Walczak
2013Cold Spring Harbor Perspectives in Biology222 citations Open access
Semantic Scholar
“ Ubiquitylation : mechanism and functions ” Review series Ubiquitin in the immune system
J. Zinngrebe, A. Montinaro, N. Peltzer, H. Walczak
2014221 citations
Semantic Scholar
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
T. Hartwig, A. Montinaro, Silvia von Karstedt, A. Sevko +9 more
2017Molecules and Cells217 citations Open access
Semantic Scholar
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
N. Peltzer, M. Darding, A. Montinaro, Peter Draber +23 more
2018Nature194 citations Open access
Semantic Scholar
NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
Katerina Vlantis, A. Wullaert, A. Polykratis, V. Kondylis +9 more
2016Immunity188 citations Open access
Semantic Scholar
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion and metastasis
Silvia von Karstedt, A. Conti, Max Nobis, A. Montinaro +27 more
2015Cancer Cell182 citations Open access
Semantic Scholar
Linear ubiquitination: a newly discovered regulator of cell signalling.
E. Rieser, Stefanie M. Cordier, H. Walczak
2013TIBS -Trends in Biochemical Sciences. Regular ed170 citations
Semantic Scholar
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling.
N. Peltzer, M. Darding, H. Walczak
2016Trends in Cell Biology168 citations Open access
Semantic Scholar
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
Yannick Boege, Mohsen Malehmir, M. E. Healy, K. Bettermann +49 more
2017Cancer Cell147 citations Open access
Semantic Scholar
Poly-ubiquitination in TNFR1-mediated necroptosis
Yves Dondelinger, M. Darding, M. Bertrand, H. Walczak
2016Cellular and Molecular Life Sciences146 citations Open access
Semantic Scholar
Linear ubiquitination in immunity
Y. Shimizu, L. Taraborrelli, H. Walczak
2015Immunological Reviews134 citations Open access
Semantic Scholar
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes
S. Kupka, D. de Miguel, Peter Draber, L. Martino +3 more
2016Cell Reports133 citations Open access
Semantic Scholar
Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells.
V. Haselmann, Alexandra Kurz, U. Bertsch, Sebastian Hübner +27 more
2014Gastroenterology129 citations
Semantic Scholar
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries
A. Montinaro, H. Walczak
2022Cell Death and Differentiation122 citations Open access
Semantic Scholar
The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death
É. Lafont, Chahrazade Kantari-Mimoun, Peter Draber, D. de Miguel +8 more
2017EMBO Journal108 citations Open access
Semantic Scholar
Cell Death and Inflammation - A Vital but Dangerous Liaison.
N. Peltzer, H. Walczak
2019Trends in immunology104 citations Open access
Semantic Scholar
UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
M. Lewis, S. Vyse, A. Shields, S. Boeltz +5 more
2015American Journal of Human Genetics101 citations Open access
Semantic Scholar
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
L. Taraborrelli, N. Peltzer, A. Montinaro, S. Kupka +16 more
2018Nature Communications93 citations Open access
Semantic Scholar
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
J. Zinngrebe, E. Rieser, L. Taraborrelli, N. Peltzer +12 more
2016Journal of Experimental Medicine88 citations Open access
Semantic Scholar
Linear ubiquitination at a glance
M. Spit, E. Rieser, H. Walczak
2019Journal of Cell Science78 citations Open access
Semantic Scholar
TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells
M. Tuthill, A. Montinaro, J. Zinngrebe, K. Prieske +6 more
2014Oncogene76 citations Open access
Semantic Scholar
Cancer cells employ nuclear caspase-8 to overcome the p53-dependent G2/M checkpoint through cleavage of USP28
I. Müller, E. Strozyk, Sebastian Schindler, S. Beissert +15 more
2020Molecules and Cells72 citations Open access
Semantic Scholar
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila
Anna L. Aalto, Aravind K. Mohan, Lukas Schwintzer, S. Kupka +4 more
2018Cell Death and Differentiation61 citations Open access
Semantic Scholar
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis
Charis E. Teh, N. Lalaoui, R. Jain, A. Policheni +17 more
2016Nature Communications61 citations Open access
Semantic Scholar
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
J. Bolik, Freia Krause, M. Stevanovic, M. Gandraß +26 more
2021Journal of Experimental Medicine60 citations Open access
Semantic Scholar
Zebrafish Model for Functional Screening of Flow-Responsive Genes
Jovana Serbanovic-Canic, A. De Luca, C. Warboys, P. Ferreira +17 more
2016Arteriosclerosis, Thrombosis and Vascular Biology53 citations Open access
Semantic Scholar
Death Receptors and Their Ligands in Inflammatory Disease and Cancer.
Alessandro Annibaldi, H. Walczak
2020Cold Spring Harbor Perspectives in Biology51 citations Open access
Semantic Scholar
Paving TRAIL's Path with Ubiquitin.
É. Lafont, T. Hartwig, H. Walczak
2018TIBS -Trends in Biochemical Sciences. Regular ed45 citations Open access
Semantic Scholar
Apoptosis therapy: driving cancers down the road to ruin
D. Green, H. Walczak
2013Nature Medicine45 citations
Semantic Scholar
The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1β secretion in macrophages.
B. Ferguson, Stephen Newland, Sarah E. Gibbs, Panagiotis Tourlomousis +9 more
2015International Journal of Parasitology43 citations
Semantic Scholar
Formation and removal of poly‐ubiquitin chains in the regulation of tumor necrosis factor‐induced gene activation and cell death
S. Kupka, M. Reichert, Peter Draber, H. Walczak
2016The FEBS Journal40 citations Open access
Semantic Scholar
Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout
H. Ehlken, S. Krishna-Subramanian, L. Ochoa-Callejero, V. Kondylis +6 more
2014Cell Death and Differentiation40 citations Open access
Semantic Scholar
The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis
Y. Shimizu, N. Peltzer, A. Sevko, É. Lafont +3 more
2017Hepatology37 citations Open access
Semantic Scholar
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury
S. Krishna-Subramanian, S. Singer, M. Armaka, J. Banales +6 more
2019Cell Death and Differentiation32 citations Open access
Semantic Scholar
Neoadjuvant Immunotherapy in Gastrointestinal Cancers - The New Standard of Care?
B. Petricevic, J. Kabiljo, R. Zirnbauer, H. Walczak +2 more
2022Seminars in Cancer Biology31 citations Open access
Semantic Scholar
Compound heterozygous variants in OTULIN are associated with fulminant atypical late‐onset ORAS
J. Zinngrebe, B. Moepps, T. Monecke, P. Gierschik +17 more
2022EMBO Molecular Medicine29 citations Open access
Semantic Scholar

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