Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

V. Benade · SciRah

Researcher profile · Semantic Scholar

V. Benade

Share profile

V. Benade — researcher profile on SciRah

h-index: 15
Works: 98
Citations: 700

Most-cited papers

A simple and rapid method to collect the cerebrospinal fluid of rats and its application for the assessment of drug penetration into the central nervous system.
R. Nirogi, V. Kandikere, K. Mudigonda, G. Bhyrapuneni +3 more
2009Journal of Neuroscience Methods125 citations
Semantic Scholar
Modulation of the cyclooxygenase pathway via inhibition of nitric oxide production contributes to the anti-inflammatory activity of kaempferol.
M. Mahat, N. Kulkarni, S. Vishwakarma, Farhin R Khan +7 more
2010European Journal of Pharmacology53 citations
Semantic Scholar
A sensitive and selective quantification of catecholamine neurotransmitters in rat microdialysates by pre-column dansyl chloride derivatization using liquid chromatography-tandem mass spectrometry.
R. Nirogi, Prashanth Komarneni, V. Kandikere, R. Boggavarapu +3 more
2013Journal of chromatography. B, Analytical technologies in the biomedical and life sciences49 citations
Semantic Scholar
Synthesis and SAR of Imidazo[1,5-a]pyridine derivatives as 5-HT4 receptor partial agonists for the treatment of cognitive disorders associated with Alzheimer's disease.
R. Nirogi, A. R. Mohammed, A. Shinde, Narsimha Bogaraju +10 more
2015European journal of medicinal chemistry45 citations Open access
Semantic Scholar
Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders
R. Nirogi, P. Jayarajan, A. Shinde, A. R. Mohammed +6 more
2023Biomolecules42 citations Open access
Semantic Scholar
Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease.
R. Nirogi, A. Shinde, R. Kambhampati, A. R. Mohammed +13 more
2017Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
SUVN-502, a novel, potent, pure, and orally active 5-HT6 receptor antagonist: pharmacological, behavioral, and neurochemical characterization
R. Nirogi, Renny Abraham, V. Benade, R. Medapati +8 more
2019Behavioural Pharmacology33 citations
Semantic Scholar
Approach to reduce the non-specific binding in microdialysis.
R. Nirogi, V. Kandikere, G. Bhyrapuneni, V. Benade +4 more
2012Journal of Neuroscience Methods26 citations
Semantic Scholar
Effect of masupirdine (SUVN‐502) on cognition in patients with moderate Alzheimer's disease: A randomized, double‐blind, phase 2, proof‐of‐concept study
R. Nirogi, J. Ieni, V. Goyal, J. Ravula +9 more
2022Alzheimer's & Dementia24 citations Open access
Semantic Scholar
Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists.
R. Nirogi, A. R. Mohammed, A. Shinde, Shankar Reddy Gagginapally +11 more
2018Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
Effect of Bauhinia variegate Bark Extract on Blood Glucose Level in Normal and Alloxanised Diabetic Rats
B. Koti, S. Biradar, R. Karadi, A. Taranalli +1 more
200921 citations
Semantic Scholar
Concurrent administration of atypical antipsychotics and donepezil: drug interaction study in rats
R. Nirogi, G. Bhyrapuneni, V. Kandikere, V. Benade +5 more
2012European journal of drug metabolism and pharmacokinetics20 citations
Semantic Scholar
Difference in the norepinephrine levels of experimental and non-experimental rats with age in the object recognition task.
R. Nirogi, Renny Abraham, P. Jayarajan, R. Medapati +7 more
2012Brain Research19 citations
Semantic Scholar
Discovery and Development of N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H3 Receptor Inverse Agonist with Robust Wake-Promoting Activity.
R. Nirogi, A. Shinde, A. R. Mohammed, R. Badange +13 more
2019Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Discovery and Preclinical Characterization of Usmarapride (SUVN-D4010): A Potent, Selective 5-HT4 Receptor Partial Agonist for the Treatment of Cognitive Deficits Associated with Alzheimer's Disease.
R. Nirogi, A. R. Mohammed, A. Shinde, Shankar Reddy Gagginapally +19 more
2021Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Potential beneficial effects of masupirdine (SUVN‐502) on agitation/aggression and psychosis in patients with moderate Alzheimer's disease: Exploratory post hoc analyses
R. Nirogi, P. Jayarajan, V. Benade, A. Shinde +12 more
2022International Journal of Geriatric Psychiatry15 citations Open access
Semantic Scholar
LC-MS/MS method for the quantification of almotriptan in dialysates: application to rat brain and blood microdialysis study.
R. Nirogi, D. Ajjala, V. Kandikere, R. Aleti +5 more
2013Journal of Pharmaceutical and Biomedical Analysis14 citations
Semantic Scholar
Samelisant (SUVN-G3031), a potent, selective and orally active histamine H3 receptor inverse agonist for the potential treatment of narcolepsy: pharmacological and neurochemical characterisation
R. Nirogi, V. Benade, S. Daripelli, R. Subramanian +9 more
2021Psychopharmacology13 citations
Semantic Scholar
Mechanistic evaluation of tapentadol in reducing the pain perception using in‐vivo brain and spinal cord microdialysis in rats
V. Benade, R. Nirogi, G. Bhyrapuneni, S. Daripelli +4 more
2017European Journal of Pharmacology11 citations
Semantic Scholar
Usmarapride (SUVN-D4010), a 5-HT4 receptor partial agonist for the potential treatment of Alzheimer's disease: Behavioural, neurochemical and pharmacological profiling.
R. Nirogi, Venkata Ramalingayya Grandhi, R. Medapati, Narender Ganuga +11 more
2023European Journal of Pharmacology10 citations
Semantic Scholar
Samelisant (SUVN-G3031), a histamine 3 receptor inverse agonist: Results from the phase 2 double-blind randomized placebo-controlled study for the treatment of excessive daytime sleepiness in adult patients with narcolepsy.
R. Nirogi, A. Shinde, V. Goyal, J. Ravula +12 more
2024Sleep Medicine8 citations
Semantic Scholar
Histamine 3 receptor inverse agonist Samelisant (SUVN-G3031): Pharmacological characterization of an investigational agent for the treatment of cognitive disorders
R. Nirogi, Venkata Ramalingayya Grandhi, R. Medapati, Narender Ganuga +11 more
2021Journal of Psychopharmacology8 citations
Semantic Scholar
Effect of Concurrent Use of Memantine on the Efficacy of Masupirdine (SUVN-502): A Post Hoc Analysis of a Phase 2 Randomized Placebo-Controlled Study
R. Nirogi, V. Goyal, V. Benade, R. Subramanian +7 more
2022Neurological Therapeutics6 citations Open access
Semantic Scholar
Therapeutic Potential of 5-HT6 Antagonist SB399885 in Traumatic Stress Disorder
Renny Abraham, R. Nirogi, A. Shinde, V. Benade
2014Drug Research5 citations
Semantic Scholar
Hits and misses with animal models of narcolepsy and the implications for drug discovery
R. Nirogi, P. Jayarajan, V. Benade, Renny Abraham +1 more
2024Expert Opinion on Drug Discovery4 citations
Semantic Scholar
Safety, Tolerability, and Pharmacokinetics of Ropanicant (SUVN-911), a Novel Alpha4 Beta2 Nicotinic Acetylcholine Receptor (α4β2 nAChR) Antagonist, in Healthy Adult and Elderly Subjects
R. Nirogi, V. Benade, V. Goyal, S. Pandey +6 more
2022Clinical drug investigation4 citations
Semantic Scholar
P3‐016: SUVN‐D4010, A Potent and Selective 5‐HT4 Receptor Partial Agonist: Safety, Tolerability and Pharmacokinetics in Humans
P. Jayarajan, G. Bhyrapuneni, K. Mudigonda, Kiran Kumar Penta +11 more
20164 citations Open access
Semantic Scholar
P1‐310: Suvn‐g3031, an h3 receptor inverse agonist, produces procognitive effects without affecting sleep in preclinical models
V. Benade, S. Daripelli, Jagadeesh Babu Thentu, Arunkumar Manoharan +8 more
20154 citations
Semantic Scholar
Resveratrol, a calorie restriction mimetic, protects AlCl3-induced neurotoxicity and cognitive deficits in rats via inhibition of oxidative stress
V. Benade, P. Jayarajan, N. Krishnadas, R. Nirogi
2025Naunyn-Schmiedeberg's Archives of Pharmacology3 citations
Semantic Scholar
0609 Samelisant, Histamine 3 Receptor Agonist for the Potential Treatment of Excessive Daytime Sleepiness in Patients with Narcolepsy
R. Nirogi, J. Ravula, P. Jayarajan, V. Goyal +3 more
2023Sleep3 citations Open access
Semantic Scholar
Metformin, a calorie restriction mimetic for the treatment of Alzheimer’s disease: A preclinical investigation
V. Benade, P. Jayarajan, N. Krishnadas, Venkatesh Kamuju +2 more
2021Alzheimer's & Dementia3 citations
Semantic Scholar
1‐[2‐(1‐Cyclobutylpiperidin‐4‐yloxy)‐6,7‐dihydro‐4H‐thiazolo[5,4‐c]pyridin‐5‐yl]propan‐1‐one: a Histamine H3 Receptor Inverse Agonist with Efficacy in Animal Models of Cognition
R. Nirogi, A. Shinde, R. Badange, V. Reballi +14 more
2021ChemMedChem3 citations
Semantic Scholar
Masupirdine (SUVN‐502): Novel treatment option for the management of behavioral and psychological symptoms in patients with Alzheimer’s disease
R. Nirogi, P. Jayarajan, A. Shinde, Renny Abraham +4 more
2020Alzheimer's & Dementia3 citations Open access
Semantic Scholar
0054 SUVN-G3031, a Histamine H3 Receptor Inverse Agonist Produces Wake Promoting Effect in Orexin-2-saporin Lesioned Rats
V. Benade, S. Daripelli, Chaitanya Tirumalasetty, R. Subramanian +3 more
2019Sleep3 citations
Semantic Scholar
Simultaneous monitoring of electroencephalographic characteristics in animals subjected to behavioral tests: a preclinical investigation
R. Nirogi, S. Daripelli, V. Benade, Chaitanya Tirumalasetty +2 more
2017Behavioural Pharmacology3 citations
Semantic Scholar
P1‐085: SUVN‐502, Potent and Pure 5‐HT6 Receptor Antagonist: Proof‐of‐Concept Study Design in Moderate Alzheimer’s Disease Patients
R. Nirogi, K. Mudigonda, Kiran Kumar Penta, G. Bhyrapuneni +10 more
20163 citations Open access
Semantic Scholar
P3‐451: SUVN‐502: A potent and selective 5‐HT6 antagonist, potential drug for the treatment of Alzheimer's disease
R. Nirogi, V. Kandikere, K. Mudigonda, G. Bhyrapuneni +8 more
20113 citations Open access
Semantic Scholar
Masupirdine (SUVN-502): An Update on the Phase-3 Clinical Development Program Targeting Agitation in Patients with Dementia of Alzheimer’s Type (P1-3.020)
R. Nirogi, J. Ravula, S. Jetta, V. Goyal +9 more
2025Neurology2 citations
Semantic Scholar
P1‐309: Suvn‐d4010: A novel 5‐ht4 receptor partial agonist for the treatment of Alzheimer's disease
N. Muddana, R. Subramanian, Rajesh Babu Medapati, Renny Abraham +9 more
20152 citations
Semantic Scholar
P3‐378: Misfolded superoxide dismutase 1 (SOD1) as a novel target for Alzheimer's disease
G. Bhyrapuneni, N. Muddana, V. Kandikere, V. Benade +3 more
20102 citations
Semantic Scholar
Samelisant (SUVN-G3031), a histamine H3 receptor inverse agonist, as a potential treatment for narcolepsy: a phase-2 drug evaluation
R. Nirogi, A. Shinde, R. Subramanian, Veera Raghava Chowdary Palacharla +4 more
2026Expert Opinion on Investigational Drugs1 citations
Semantic Scholar
Samelisant (SUVN-G3031): Positive Results from Phase-2 Proof-of-concept, Double-blind, Placebo-controlled Study in Patients with Narcolepsy and an Update on Further Clinical Development (S6.004)
R. Nirogi, J. Ravula, S. Jetta, V. Goyal +9 more
2025Neurology1 citations
Semantic Scholar
Update on the Development of SUVN‐I6107: A True Positive Allosteric Modulator of the Muscarinic M1 Acetylcholine Receptor for the Treatment of Dementia
V. Benade, A. Shinde, R. Badange, Mohammed Abdul Rasheed +10 more
2025Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Samelisant (SUVN-G3031) - Topline Results from the Phase-2 Proof-of-Concept Double-blind, Placebo-controlled Study in Patients with Narcolepsy (P10-9.002)
R. Nirogi, P. Jayarajan, V. Benade, V. Goyal +4 more
2024Neurology1 citations
Semantic Scholar
Bioequivalence, food effect and comparative pharmacokinetics of SUVN-1105, a novel granule formulation of abiraterone acetate, to Zytiga in healthy male subjects
R. Nirogi, J. Ravula, V. Benade, V. Goyal +6 more
2023Cancer Chemotherapy and Pharmacology1 citations
Semantic Scholar
0051 Samelisant, a H3 Receptor Inverse Agonist for the Potential Treatment of Excessive Daytime Sleepiness in Parkinson’s Disease
R. Nirogi, V. Benade, Renny Abraham, Jagadeesh Babu Thentu +5 more
2023Sleep1 citations Open access
Semantic Scholar
Masupirdine (SUVN‐502) for the Potential Treatment of Agitation in Patients with Dementia of the Alzheimer’s Type: Preliminary Efficacy and Phase‐3 Study Design
R. Nirogi, Renny Abraham, J. Ravula, S. Jetta +8 more
2023Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Effects of Masupirdine (SUVN‐502) on Agitation/Aggression and Psychosis in Patients with Probable Alzheimer’s Disease: A Post Hoc Analysis
R. Nirogi, P. Jayarajan, Renny Abraham, Jayaprakash Tadiparthi +9 more
2022Alzheimer's & Dementia1 citations
Semantic Scholar
004 Samelisant (SUVN-G3031), Differentiating features over current treatments of narcolepsy
A. Shinde, R. Subramanian, R. Palacharla, V. Benade +6 more
20211 citations Open access
Semantic Scholar
Masupirdine (SUVN‐502): A promising clinical candidate for the management of agitation in Alzheimer’s dementia
R. Nirogi, P. Jayarajan, Jayaprakash Tadiparthi, A. Shinde +7 more
2021Alzheimer's & Dementia1 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Nirogi×47
Invite
R. Nirogi — researcher profile on SciRah
P. Jayarajan×32
Invite
P. Jayarajan — researcher profile on SciRah
A. Shinde×30
Invite
A. Shinde — researcher profile on SciRah
R. Subramanian×25
Invite
R. Subramanian — researcher profile on SciRah

×25

Invite

V. Goyal — researcher profile on SciRah

Renny Abraham×23

Invite

Renny Abraham — researcher profile on SciRah

G. Bhyrapuneni×18

Invite

G. Bhyrapuneni — researcher profile on SciRah

Invite

S. Pandey — researcher profile on SciRah

Invite

V. Jasti — researcher profile on SciRah

Invite

N. Muddana — researcher profile on SciRah

A. R. Mohammed×13

Invite

A. R. Mohammed — researcher profile on SciRah

Invite

R. Badange — researcher profile on SciRah