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Lydia W. S. Finley · SciRah

Researcher profile · Semantic Scholar

Lydia W. S. Finley

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Lydia W. S. Finley — researcher profile on SciRah

h-index: 39
Works: 76
Citations: 9,569

Most-cited papers

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey, Lydia W. S. Finley, Justin R. Cross, C. Allis +1 more
2014Nature899 citations Open access
Semantic Scholar
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
Lydia W. S. Finley, A. Carracedo, J. Lee, Amanda L. Souza +8 more
2011Cancer Cell833 citations Open access
Semantic Scholar
Sirtuin Regulation of Mitochondria - Energy Production, Apoptosis, and Signaling
E. Verdin, Matthew D. Hirschey, Lydia W. S. Finley, M. Haigis
2010TIBS -Trends in Biochemical Sciences. Regular ed661 citations Open access
Semantic Scholar
Adrenergic nerves activate an angio-metabolic switch in prostate cancer
A. Zahalka, A. Arnal-Estapé, Maria Maryanovich, Fumio Nakahara +3 more
2017Science482 citations Open access
Semantic Scholar
Hypoxia Induces Production of L-2-Hydroxyglutarate
A. Intlekofer, Raymond G. Dematteo, S. Venneti, Lydia W. S. Finley +7 more
2015Cell Metabolism469 citations Open access
Semantic Scholar
Regulation and function of the mammalian tricarboxylic acid cycle
Paige K. Arnold, Lydia W. S. Finley
2022Journal of Biological Chemistry466 citations Open access
Semantic Scholar
SIRT4 has tumor suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism
S. Jeong, C. Xiao, Lydia W. S. Finley, T. Lahusen +17 more
2013Cancer Cell448 citations Open access
Semantic Scholar
Serine catabolism regulates mitochondrial redox control during hypoxia
Jiang-Bin Ye, Jing Fan, S. Venneti, Y. Wan +11 more
2014Cancer Discovery416 citations Open access
Semantic Scholar
Short-term calorie restriction enhances skeletal muscle stem cell function
M. Cerletti, Young C. Jang, Lydia W. S. Finley, M. Haigis +1 more
2012Cell Stem Cell401 citations Open access
Semantic Scholar
Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity
Lydia W. S. Finley, W. Haas, V. Desquiret-Dumas, D. Wallace +3 more
2011PLoS ONE371 citations Open access
Semantic Scholar
Metabolic signatures of cancer cells and stem cells
A. Intlekofer, Lydia W. S. Finley
2019Nature Metabolism296 citations Open access
Semantic Scholar
A non-canonical tricarboxylic acid cycle underlies cellular identity
Paige K. Arnold, Benjamin T. Jackson, Katrina I. Paras, J. S. Brunner +7 more
2022Nature268 citations Open access
Semantic Scholar
Alpha-ketoglutarate links p53 to cell fate during tumor suppression
John P. Iv Morris, Jossie J. Yashinskie, R. Koche, R. Chandwani +10 more
2019Nature255 citations Open access
Semantic Scholar
What is cancer metabolism?
Lydia W. S. Finley
2023Cell246 citations Open access
Semantic Scholar
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
Lydia W. S. Finley, M. Haigis
2009Ageing Research Reviews219 citations Open access
Semantic Scholar
Acetylation-Dependent Regulation of Skp2 Function
H. Inuzuka, Da-Ming Gao, Lydia W. S. Finley, Wen Yang +14 more
2012Cell211 citations Open access
Semantic Scholar
Metabolic regulation of chromatin modifications and gene expression
J. Schvartzman, C. Thompson, Lydia W. S. Finley
2018Journal of Cell Biology210 citations Open access
Semantic Scholar
Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition
James J. Harding, M. Lowery, A. Shih, J. Schvartzman +28 more
2018bioRxiv194 citations Open access
Semantic Scholar
SIRT3 is a Mitochondrial Tumor Suppressor: A Scientific Tale that Connects Aberrant Cellular ROS, the Warburg Effect, and Carcinogenesis
M. Haigis, Chu-Xia Deng, Lydia W. S. Finley, Hyun-Seok Kim +1 more
2012Cancer Research186 citations Open access
Semantic Scholar
Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases
Sanjeethan C. Baksh, Lydia W. S. Finley
2020Trends in Cell Biology149 citations Open access
Semantic Scholar
SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation
Gaelle Laurent, V. D. de Boer, Lydia W. S. Finley, Meredith O. Sweeney +7 more
2013Molecular and Cellular Biology144 citations Open access
Semantic Scholar
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
Natalie J. German, H. Yoon, R. Yusuf, J. P. Murphy +13 more
2016Molecules and Cells143 citations Open access
Semantic Scholar
Metabolic regulation by SIRT3: implications for tumorigenesis
Lydia W. S. Finley, M. Haigis
2012Trends in Molecular Medicine131 citations Open access
Semantic Scholar
Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
Daniela Cornacchia, Chao Zhang, B. Zimmer, Sun-Young Chung +14 more
2019Cell Stem Cell120 citations Open access
Semantic Scholar
Extracellular serine controls epidermal stem cell fate and tumor initiation
Sanjeethan C. Baksh, P. Todorova, S. Gur-Cohen, B. Hurwitz +6 more
2020Nature Cell Biology116 citations Open access
Semantic Scholar
A century of the Warburg effect
Craig B. Thompson, Karen H. Vousden, Randall S. Johnson, Willem H. Koppenol +7 more
2023Nature Metabolism112 citations
Semantic Scholar
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels
A. Peserico, Fulvio Chiacchiera, V. Grossi, A. Matrone +10 more
2013Cellular and Molecular Life Sciences108 citations Open access
Semantic Scholar
Metabolic regulation of the hallmarks of stem cell biology
Benjamin T. Jackson, Lydia W. S. Finley
2024Cell Stem Cell103 citations Open access
Semantic Scholar
Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction
Lydia W. S. Finley, J. Lee, Amanda L. Souza, V. Desquiret-Dumas +6 more
2012Proceedings of the National Academy of Sciences of the United States of America102 citations Open access
Semantic Scholar
SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1
S. Jeong, J. Lee, Lydia W. S. Finley, P. Schmidt +2 more
2014Oncogene87 citations Open access
Semantic Scholar
Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag
S. Dey, Grigory S. Filonov, Anthony O. Olarerin-George, Benjamin T. Jackson +2 more
2021Nature Chemical Biology80 citations Open access
Semantic Scholar
Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3
J. Lee, R. V. D. van de Ven, Elma Zaganjor, M. Ng +10 more
2018Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization
Harihar Basnet, Lin Tian, K. Ganesh, Yun-Han Huang +4 more
2019eLife65 citations Open access
Semantic Scholar
Metabolic determinants of tumor initiation
J. Brunner, Lydia W. S. Finley
2022Nature Reviews Endocrinology61 citations Open access
Semantic Scholar
Glutamine independence is a selectable feature of pluripotent stem cells
Santosha A. Vardhana, Paige K. Arnold, Bess P. Rosen, Yan-Yang Chen +5 more
2019Nature Metabolism61 citations Open access
Semantic Scholar
Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system
Peter C. W. Lee, J. Dodart, Liviu Aron, Lydia W. S. Finley +4 more
2013Molecules and Cells56 citations Open access
Semantic Scholar
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity
Lydia W. S. Finley, Santosha A. Vardhana, Bryce W. Carey, Direna Alonso-Curbelo +9 more
2018Nature Cell Biology52 citations Open access
Semantic Scholar
SnapShot: cancer metabolism pathways.
Lydia W. S. Finley, Ji Zhang, Jiang-Bin Ye, P. Ward +1 more
2013Cell Metabolism46 citations Open access
Semantic Scholar
Metabolic adaptations direct cell fate during tissue regeneration
A. Chaves-Perez, S. Millman, Sudha Janaki-Raman, Yu-Jui Ho +12 more
2025Nature44 citations Open access
Semantic Scholar
Cooperative nutrient scavenging is an evolutionary advantage in cancer
Gizem Guzelsoy, Setiembre D Elorza, Manon Ros, Logan T Schachtner +10 more
2025Nature37 citations Open access
Semantic Scholar
SnapShot: Cancer metabolism.
J. Brunner, Lydia W. S. Finley
2021Molecules and Cells31 citations
Semantic Scholar
Leucine retention in lysosomes is regulated by starvation
Urmi Bandyopadhyay, P. Todorova, N. Pavlova, Y. Tada +3 more
2022Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
Amino acid intake strategies define pluripotent cell states
P. Todorova, Benjamin T. Jackson, Vidur Garg, Katrina I. Paras +7 more
2022bioRxiv15 citations Open access
Semantic Scholar
Metabolic signal curbs cancer-cell migration
Lydia W. S. Finley
2019Nature15 citations Open access
Semantic Scholar
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
S. Millman, Almudena Chaves-Pérez, Sudha Janaki-Raman, Yu-Jui Ho +15 more
2024Blood14 citations Open access
Semantic Scholar
Metabolic diversity drives cancer cell invasion
Sanjeethan C. Baksh, Lydia W. S. Finley
2022Nature12 citations
Semantic Scholar
Intracellular metabolic gradients dictate dependence on exogenous pyruvate
Benjamin T. Jackson, Angela M Montero, Sangita Chakraborty, J. S. Brunner +5 more
2025Nature Metabolism10 citations
Semantic Scholar
The integrated stress response fine-tunes stem cell fate decisions in response to serine deprivation and tissue injury
Jesse S. S. Novak, Lisa Polak, Sanjeethan C. Baksh, D. Barrows +18 more
2025Cell Metabolism9 citations Open access
Semantic Scholar
Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle
Abigail Xie, J. S. Brunner, Sangita Chakraborty, Angela M Montero +11 more
2026Cell8 citations Open access
Semantic Scholar
Metabolic decisions in development and disease—a Keystone Symposia report
J. Cable, O. Pourquié, K. Wellen, Lydia W. S. Finley +21 more
2021Annals of the New York Academy of Sciences8 citations Open access
Semantic Scholar

Frequent co-authors

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M. Haigis×15
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M. Haigis — researcher profile on SciRah
Benjamin T. Jackson×8
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Benjamin T. Jackson — researcher profile on SciRah
C. Thompson×7
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C. Thompson — researcher profile on SciRah
J. S. Brunner×6
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×5

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J. Lee — researcher profile on SciRah

Paige K. Arnold×5

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Paige K. Arnold — researcher profile on SciRah

Sanjeethan C. Baksh×5

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Sanjeethan C. Baksh — researcher profile on SciRah

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S. Jeong — researcher profile on SciRah

Katrina I. Paras×4

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Katrina I. Paras — researcher profile on SciRah

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P. Todorova — researcher profile on SciRah

Anna E. Bridgeman×4

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Anna E. Bridgeman — researcher profile on SciRah

Bryce W. Carey×3

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Bryce W. Carey — researcher profile on SciRah