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M. Lowery · SciRah

Researcher profile · Semantic Scholar

M. Lowery

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M. Lowery — researcher profile on SciRah

h-index: 44
Works: 204
Citations: 15K

Most-cited papers

Mutational Landscape of Metastatic Cancer Revealed from Prospective Clinical Sequencing of 10,000 Patients
A. Zehir, R. Benayed, Ronak H. Shah, Aijazuddin Syed +96 more
2017Nature Medicine3,034 citations Open access
Semantic Scholar
Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
G. Abou-Alfa, T. Macarulla, M. Javle, R. Kelley +22 more
2020The Lancet Oncology857 citations Open access
Semantic Scholar
Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma.
M. Javle, M. Lowery, R. Shroff, K. Weiss +25 more
2017Journal of Clinical Oncology580 citations Open access
Semantic Scholar
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial.
S. Rha, D. Oh, P. Yanez, Yu-Xian Bai +19 more
2023The Lancet Oncology563 citations Open access
Semantic Scholar
Comprehensive molecular profiling of intra- and extrahepatic cholangiocarcinomas: potential targets for intervention.
M. Lowery, R. Ptashkin, E. Jordan, M. Berger +16 more
2018Clinical Cancer Research497 citations Open access
Semantic Scholar
Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation
A. Zhu, T. Macarulla, M. Javle, R. Kelley +23 more
2021JAMA Oncology460 citations Open access
Semantic Scholar
Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
Z. Hu, J. Shia, Z. Stadler, A. Varghese +13 more
2018Clinical Cancer Research341 citations Open access
Semantic Scholar
Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation.
E. O'Reilly, Jonathan W. Lee, M. Zalupski, M. Capanu +16 more
2020Journal of Clinical Oncology324 citations Open access
Semantic Scholar
Assessment of Hepatic Arterial Infusion of Floxuridine in Combination With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma: A Phase 2 Clinical Trial.
A. Cercek, T. Boerner, B. Tan, Joanne F. Chou +27 more
2019JAMA Oncology206 citations Open access
Semantic Scholar
Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms
M. Lowery, W. Wong, E. Jordan, Jonathan W. Lee +29 more
2018Journal of the National Cancer Institute203 citations Open access
Semantic Scholar
Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition
James J. Harding, M. Lowery, A. Shih, J. Schvartzman +28 more
2018bioRxiv194 citations Open access
Semantic Scholar
Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study
M. Lowery, H. Burris, F. Janku, R. Shroff +18 more
2019The Lancet Gastroenterology and Hepatology182 citations Open access
Semantic Scholar
Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma
M. Noel, E. O'Reilly, B. Wolpin, D. Ryan +11 more
2019Investigational new drugs176 citations Open access
Semantic Scholar
Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma
T. Boerner, E. Drill, L. Pak, B. Nguyen +28 more
2021Hepatology151 citations Open access
Semantic Scholar
Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial
John V. Reynolds, S. Preston, Brian O'Neill, M. Lowery +50 more
2023The Lancet Gastroenterology and Hepatology141 citations Open access
Semantic Scholar
Phase I Trial Evaluating Cisplatin, Gemcitabine and Veliparib in Two Patient Cohorts: Germline-BRCA Mutation Carriers and BRCA Wild-Type Pancreas Ductal Adenocarcinoma
E. O'Reilly, Jonathan W. Lee, M. Lowery, M. Capanu +17 more
2018Cancer103 citations Open access
Semantic Scholar
Phase I study of AG-120, an IDH1 mutant enzyme inhibitor: Results from the cholangiocarcinoma dose escalation and expansion cohorts.
M. Lowery, G. Abou-Alfa, H. Burris, F. Janku +16 more
201797 citations
Semantic Scholar
Neo-AEGIS (Neoadjuvant trial in Adenocarcinoma of the Esophagus and Esophago-Gastric Junction International Study): Preliminary results of phase III RCT of CROSS versus perioperative chemotherapy (Modified MAGIC or FLOT protocol). (NCT01726452).
J. Reynolds, S. Preston, B. O’Neill, M. Lowery +16 more
202195 citations
Semantic Scholar
Advances in the curative management of oesophageal cancer
J. Bolger, C. Donohoe, M. Lowery, J. Reynolds
2021British Journal of Cancer91 citations Open access
Semantic Scholar
Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors
Bin Fan, I. Mellinghoff, P. Wen, M. Lowery +12 more
2019Investigational new drugs81 citations Open access
Semantic Scholar
Frequency, Morbidity, and Mortality of Bone Metastases in Advanced Hepatocellular Carcinoma.
J. Harding, G. Abu-Zeinah, Joanne F. Chou, D. Owen +8 more
2018The Journal of the National Comprehensive Cancer Network63 citations Open access
Semantic Scholar
Second Line Chemotherapy in Advanced Biliary Cancers: A Retrospective, Multicenter Analysis of Outcomes
M. Lowery, L. Goff, Bridget P. Keenan, E. Jordan +12 more
2019Cancer62 citations Open access
Semantic Scholar
Genomic Landscape of Pancreatic Adenocarcinoma in Younger vs Older Patients: Does Age Matter?
I. Ben-Aharon, Moshe Elkabets, Raphael A. Pelossof, Kenneth H. Yu +5 more
2019Clinical Cancer Research62 citations Open access
Semantic Scholar
VP1-2023: Pembrolizumab (pembro) plus chemotherapy (chemo) as first-line therapy for advanced HER2-negative gastric or gastroesophageal junction (G/GEJ) cancer: Phase III KEYNOTE-859 study
S. Rha, L. Wyrwicz, P. E. Yanez Weber, Y. Bai +16 more
2023Annals of Oncology61 citations Open access
Semantic Scholar
Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes.
A. Varghese, Isha Singh, Rituraj Singh, S. Kunte +17 more
2021Journal of the National Cancer Institute59 citations Open access
Semantic Scholar
Noninvasive Detection of Polyclonal Acquired Resistance to FGFR Inhibition in Patients With Cholangiocarcinoma Harboring FGFR2 Alterations
A. Varghese, J. Patel, Y. Janjigian, Fanli Meng +8 more
2021JCO Precision Oncology57 citations Open access
Semantic Scholar
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
A. Zehir, R. Benayed, Ronak H. Shah, Aijazuddin Syed +96 more
2017Nature Medicine56 citations Open access
Semantic Scholar
Ampullary Cancer: Evaluation of Somatic and Germline Genetic Alterations and Association with Clinical Outcomes
W. Wong, M. Lowery, M. Berger, Y. Kemel +14 more
2019Cancer42 citations Open access
Semantic Scholar
Germline Alterations in Patients with Biliary Tract Cancers: A Spectrum of Significant and Previously Under Appreciated Findings
Hannah Maynard, Z. Stadler, M. Berger, D. Solit +11 more
2020Cancer41 citations Open access
Semantic Scholar
CROSS Versus FLOT Regimens in Esophageal and Esophagogastric Junction Adenocarcinoma
N. Donlon, B. Moran, Anitha Kamilli, M. Davern +10 more
2022Annals of Surgery39 citations
Semantic Scholar
New systemic treatment paradigms in advanced biliary tract cancer and variations in patient access across Europe
L. Rimassa, A. Lamarca, G. O'Kane, Julien Edeline +18 more
2025The Lancet Regional Health - Europe33 citations Open access
Semantic Scholar
Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers
M. Lowery, Mikaela Bradley, Joanne F. Chou, M. Capanu +16 more
2018Clinical Cancer Research30 citations Open access
Semantic Scholar
Moving the Needle on Precision Medicine in Pancreatic Cancer.
G. O'Kane, M. Lowery
2022Journal of Clinical Oncology28 citations
Semantic Scholar
A randomized, multicenter, phase II trial of gemcitabine (G), cisplatin (C) +/- veliparib (V) in patients with pancreas adenocarcinoma (PDAC) and a known germline (g)BRCA/ PALB2 mutation.
E. O'Reilly, Jonathan W. Lee, M. Zalupski, M. Capanu +16 more
2020Journal of Clinical Oncology28 citations
Semantic Scholar
FLOT-regimen Chemotherapy and Transthoracic en bloc Resection for Esophageal and Junctional Adenocarcinoma
N. Donlon, A. Kammili, R. Roopnarinesingh, M. Davern +11 more
2021Annals of Surgery25 citations Open access
Semantic Scholar
Molecular and morphological changes induced by ivosidenib correlate with efficacy in mutant-IDH1 cholangiocarcinoma.
E. Aguado-Fraile, A. Tassinari, Y. Ishii, C. Sigel +9 more
2021Future Oncology24 citations Open access
Semantic Scholar
PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe
K. Taskén, S. H. Haj Mohammad, G. L. Fagereng, Ragnhild Sørum Falk +21 more
2024Acta oncologica22 citations Open access
Semantic Scholar
Visceral Thrombosis in Pancreas Ductal Adenocarcinoma: Incidence, Management and Implications
Angel Mier-Hicks, M. Raj, R. Do, Kenneth H. Yu +3 more
2018Clinical colorectal cancer22 citations Open access
Semantic Scholar
Brain Metastases (BM) in Pancreatic Ductal Adenocarcinoma (PDAC): Assessment of molecular genotype-phenotype features. An Entity with an Increasing Incidence?
E. Jordan, M. Lowery, O. Basturk, P. Allen +8 more
2018Clinical colorectal cancer21 citations Open access
Semantic Scholar
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
Suhasini Joshi, E. D. Gomes, Tai Wang, A. Corben +36 more
2021Communications Biology19 citations Open access
Semantic Scholar
The Cancer-Immune Set Point in Oesophageal Cancer
R. Power, M. Lowery, J. Reynolds, M. Dunne
2020Frontiers in Oncology18 citations Open access
Semantic Scholar
DNA Damage Repair Deficiency in Pancreatic Ductal Adenocarcinoma: Preclinical Models and Clinical Perspectives
Jojanneke Stoof, E. Harrold, Sarah Mariottino, M. Lowery +1 more
2021Frontiers in Cell and Developmental Biology17 citations Open access
Semantic Scholar
Circulating Tumor and Invasive Cell Gene Expression Profile Predicts Treatment Response and Survival in Pancreatic Adenocarcinoma
Kenneth H. Yu, Mark Ricigliano, B. McCarthy, Joanne F. Chou +6 more
2018Cancers16 citations Open access
Semantic Scholar
Liver and Bile Duct Cancer
G. Abou-Alfa, W. Jarnagin, I. El Dika, M. D'Angelica +9 more
2020Abeloff's Clinical Oncology14 citations
Semantic Scholar
Neo-AEGIS (Neoadjuvant Trial in Adenocarcinoma of the Esophagus and Esophago-Gastric Junction International Study): Final primary outcome analysis.
J. Reynolds, S. Preston, B. O'Neill, M. Lowery +16 more
2023Journal of Clinical Oncology13 citations Open access
Semantic Scholar
Modifiable Risk Factors and Risk of Colorectal and Endometrial Cancers in Lynch Syndrome: A Systematic Review and Meta-Analysis
R. Power, Damien E Doherty, I. Parker, D. J. Gallagher +2 more
2024JCO Precision Oncology12 citations
Semantic Scholar
KEYNOTE-859 study of pembrolizumab plus chemotherapy for advanced HER2-negative gastric or gastroesophageal junction (G/GEJ) cancer: Outcomes in the protocol-specified PD-L1–selected populations.
S. Rha, L. Wyrwicz, Patricio Eduardo Yanez Weber, Yuxian Bai +16 more
2023Journal of Clinical Oncology11 citations
Semantic Scholar
Modifiable risk factors for cancer among people with lynch syndrome: an international, cross-sectional survey
R. Power, Damien E Doherty, R. Horgan, Patrick J. Fahey +3 more
2024Hereditary Cancer in Clinical Practice10 citations Open access
Semantic Scholar
Modern oncological and operative outcomes in oesophageal cancer: the St. James’s hospital experience
N. Donlon, N. Ravi, S. King, Moya Cunninhgam +15 more
2020Irish Journal of Medical Science10 citations
Semantic Scholar
Non-invasive detection of acquired resistance to FGFR inhibition in patients with cholangiocarcinoma harboring FGFR2 alterations.
A. Varghese, J. Patel, Y. Janjigian, Fanli Meng +8 more
2019Journal of Clinical Oncology10 citations
Semantic Scholar

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