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A. Wack · SciRah

Researcher profile · Semantic Scholar

A. Wack

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A. Wack — researcher profile on SciRah

h-index: 46
Works: 95
Citations: 11K

Most-cited papers

Type I interferons in infectious disease
Finlay W Mcnab, K. Mayer-Barber, A. Sher, A. Wack +1 more
2015Nature reviews. Immunology2,574 citations Open access
Semantic Scholar
Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein
S. Crotta, A. Stilla, A. Wack, A. D'Andrea +8 more
2002Journal of Experimental Medicine500 citations Open access
Semantic Scholar
Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Jack Major, S. Crotta, Miriam Llorian, Teresa M. McCabe +4 more
2020Science483 citations Open access
Semantic Scholar
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes.
Samuele Calabro, Marco Tortoli, B. Baudner, Alessandra Pacitto +5 more
2011Vaccine439 citations
Semantic Scholar
Guarding the frontiers: the biology of type III interferons
A. Wack, E. Terczyńska-Dyla, R. Hartmann
2015Nature Immunology357 citations Open access
Semantic Scholar
Pathogenic potential of interferon αβ in acute influenza infection
Sophia Davidson, S. Crotta, Teresa M. McCabe, A. Wack
2014Nature Communications348 citations Open access
Semantic Scholar
Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection
H. Aegerter, Justina Kulikauskaite, S. Crotta, H. Patel +5 more
2020Nature Immunology320 citations Open access
Semantic Scholar
The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells1
A. Seubert, E. Monaci, M. Pizza, D. O'Hagan +1 more
2008Journal of Immunology304 citations Open access
Semantic Scholar
Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection.
Konrad C. Bradley, Katja Finsterbusch, D. Schnepf, S. Crotta +5 more
2019Cell Reports274 citations Open access
Semantic Scholar
Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia
S. Crotta, Sophia Davidson, Tanel Mahlakõiv, C. Desmet +4 more
2013PLoS Pathogens256 citations Open access
Semantic Scholar
The interferon landscape along the respiratory tract impacts the severity of COVID-19
B. Sposito, A. Broggi, L. Pandolfi, S. Crotta +24 more
2021Cell235 citations Open access
Semantic Scholar
IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment
Sophia Davidson, Teresa M. McCabe, S. Crotta, H. Gad +4 more
2016EMBO Molecular Medicine233 citations Open access
Semantic Scholar
Safety of MF59 adjuvant.
V. Schultze, Vicente D'Agosto, A. Wack, D. Novicki +2 more
2008Vaccine228 citations
Semantic Scholar
Host-directed immunotherapy of viral and bacterial infections: past, present and future
R. Wallis, A. O'Garra, A. Sher, A. Wack
2022Nature reviews. Immunology225 citations Open access
Semantic Scholar
Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice.
A. Wack, B. Baudner, A. Hilbert, I. Manini +10 more
2008Vaccine204 citations
Semantic Scholar
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88
A. Seubert, Samuele Calabro, L. Santini, B. Galli +12 more
2011Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
Disease-Promoting Effects of Type I Interferons in Viral, Bacterial, and Coinfections
Sophia Davidson, M. Maini, A. Wack
2015Journal of Interferon and Cytokine Research195 citations Open access
Semantic Scholar
COVID-19 and emerging viral infections: The case for interferon lambda
L. Prokunina-Olsson, Noémie Alphonse, Ruth E Dickenson, J. Durbin +12 more
2020Journal of Experimental Medicine191 citations Open access
Semantic Scholar
The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression
Victoria Male, I. Nisoli, T. Kostrzewski, David S. J. Allan +4 more
2014Journal of Experimental Medicine186 citations Open access
Semantic Scholar
Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co‐stimulatory signal for human T cells
A. Wack, E. Soldaini, C. Tseng, S. Nuti +2 more
2001European Journal of Immunology167 citations
Semantic Scholar
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
Meike Dittmann, H. Hoffmann, M. Scull, Rachel H. Gilmore +11 more
2015Cell164 citations Open access
Semantic Scholar
Influenza A Virus Impairs Control of Mycobacterium tuberculosis Coinfection Through a Type I Interferon Receptor–Dependent Pathway
Paul S. Redford, K. Mayer-Barber, Finlay W Mcnab, E. Stavropoulos +3 more
2013Journal of Infectious Diseases148 citations Open access
Semantic Scholar
T-cell clonality in immune responses.
M. Maini, G. Casorati, P. Dellabona, A. Wack +1 more
1999Immunology today (Amsterdam. Regular ed.)147 citations
Semantic Scholar
Immunology of TLR-independent vaccine adjuvants.
E. De Gregorio, U. D’Oro, A. Wack
2009Current Opinion in Immunology126 citations
Semantic Scholar
Comparable functions of plasmacytoid and monocyte-derived dendritic cells in chronic hepatitis C patients and healthy donors.
Diego Piccioli, Simona Tavarini, S. Nuti, P. Colombatto +8 more
2005Journal of Hepatology115 citations
Semantic Scholar
Endothelial AHR activity prevents lung barrier disruption in viral infection
Jack Major, S. Crotta, Katja Finsterbusch, P. Chakravarty +9 more
2023Nature113 citations Open access
Semantic Scholar
TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza–Streptococcus pneumoniae coinfection
G. T. Ellis, Sophia Davidson, S. Crotta, Nora Branzk +2 more
2015EMBO Reports106 citations Open access
Semantic Scholar
Vaccinology at the beginning of the 21st century
A. Wack, R. Rappuoli
2005Current Opinion in Immunology105 citations Open access
Semantic Scholar
Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation.
Diego Piccioli, Chiara Sammicheli, Simona Tavarini, S. Nuti +8 more
2009Blood104 citations Open access
Semantic Scholar
Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retroelement co-option
K. Ng, J. Attig, William Bolland, George R. Young +5 more
2020Nature Genetics98 citations Open access
Semantic Scholar
MF59 Emulsion Is an Effective Delivery System for a Synthetic TLR4 Agonist (E6020)
B. Baudner, V. Ronconi, D. Casini, Marco Tortoli +5 more
2009Pharmaceutical Research90 citations
Semantic Scholar
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies
K. Ng, Nikhil Faulkner, Katja Finsterbusch, Mary Y. Wu +17 more
2022Science Translational Medicine89 citations Open access
Semantic Scholar
Teaching Old Dogs New Tricks? The Plasticity of Lung Alveolar Macrophage Subsets
Justina Kulikauskaite, A. Wack
2020Trends in immunology88 citations Open access
Semantic Scholar
Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection.
S. Crotta, M. Brazzoli, Diego Piccioli, N. Valiante +1 more
2010Journal of Hepatology84 citations
Semantic Scholar
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
A. Singhania, C. Graham, L. Gabryšová, Lúcia Moreira-Teixeira +31 more
2019Nature Communications66 citations Open access
Semantic Scholar
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck
E. Soldaini, A. Wack, U. D’Oro, S. Nuti +3 more
2003European Journal of Immunology65 citations Open access
Semantic Scholar
Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects.
S. R. Paccani, M. Boncristiano, L. Patrussi, C. Ulivieri +8 more
2005Blood59 citations Open access
Semantic Scholar
Rationally designed strings of promiscuous CD4+ T cell epitopes provide help to Haemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines
F. Falugi, R. Petracca, M. Mariani, E. Luzzi +12 more
2001European Journal of Immunology59 citations Open access
Semantic Scholar
Multiple sites of post‐activation CD8+ T cell disposal
A. Wack, P. Corbella, N. Harker, I. Crispe +1 more
1997European Journal of Immunology58 citations
Semantic Scholar
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
Noémie Alphonse, J. Wanford, A. Voak, J. Gay +20 more
2022Cell57 citations Open access
Semantic Scholar
Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival
Jennifer Müller-Winkler, R. Mitter, J. Rappe, Lesley Vanes +4 more
2020Journal of Experimental Medicine56 citations Open access
Semantic Scholar
The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development
S. Crotta, Annita Gkioka, Victoria Male, João H. Duarte +4 more
2014Journal of Immunology56 citations Open access
Semantic Scholar
Impaired immune response drives age-dependent severity of COVID-19
J. Beer, S. Crotta, A. Breithaupt, Annette Ohnemus +16 more
2022bioRxiv53 citations Open access
Semantic Scholar
Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells
S. Crotta, V. Ronconi, C. Ulivieri, C. Baldari +3 more
2006European Journal of Immunology51 citations
Semantic Scholar
Introduction of Zwitterionic Motifs into Bacterial Polysaccharides Generates TLR2 Agonists Able to Activate APCs
S. Gallorini, F. Berti, P. Parente, R. Baronio +5 more
2007Journal of Immunology50 citations Open access
Semantic Scholar
Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides
S. Gallorini, F. Berti, G. Mancuso, R. Cozzi +6 more
2009Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation
S. Crotta, M. Villa, Jack Major, Katja Finsterbusch +4 more
2023Nature Communications45 citations Open access
Semantic Scholar
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, J. Dutrieux +14 more
2017Nature Communications43 citations Open access
Semantic Scholar
Selective Janus Kinase Inhibition Preserves Interferon-Λ-mediated Antiviral Responses
D. Schnepf, S. Crotta, Thiprampai Thamamongood, M. Stanifer +13 more
2021Science immunology42 citations Open access
Semantic Scholar
Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity
M. Cabeza-Cabrerizo, C. Minutti, M. P. Da Costa, A. Cardoso +14 more
2021Science immunology41 citations Open access
Semantic Scholar

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