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M. Mrug · SciRah

Researcher profile · Semantic Scholar

M. Mrug

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M. Mrug — researcher profile on SciRah

h-index: 33
Works: 101
Citations: 4,966

Most-cited papers

Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials.
M. Irazabal, L. Rangel, E. Bergstralh, Sara L. Osborn +12 more
2015Journal of the American Society of Nephrology560 citations Open access
Semantic Scholar
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats.
L. Onuchic, Laszlo Furu, Y. Nagasawa, X. Hou +14 more
2002American Journal of Human Genetics497 citations Open access
Semantic Scholar
Angiotensin II stimulates proliferation of normal early erythroid progenitors.
M. Mrug, T. Stopka, B. Julian, J. Prchal +1 more
1997Journal of Clinical Investigation283 citations Open access
Semantic Scholar
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease.
X. Hou, M. Mrug, Bradley K. Yoder, E. Lefkowitz +4 more
2002Journal of Clinical Investigation267 citations Open access
Semantic Scholar
A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan.
F. Chebib, R. Perrone, A. Chapman, N. Dahl +7 more
2018Journal of the American Society of Nephrology227 citations Open access
Semantic Scholar
Ketosis ameliorates renal cyst growth in polycystic kidney disease
Jacob A Torres, Samantha L Kruger, Caroline Broderick, Tselmeg Amarlkhagva +5 more
2019Cell Metabolism193 citations Open access
Semantic Scholar
Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease.
C. M. Heyer, J. L. Sundsbak, K. Abebe, A. Chapman +17 more
2016Journal of the American Society of Nephrology166 citations Open access
Semantic Scholar
Comprehensive human urine standards for comparability and standardization in clinical proteome analysis
H. Mischak, W. Kolch, M. Aivaliotis, D. Bouyssié +27 more
2010PROTEOMICS - Clinical Applications162 citations Open access
Semantic Scholar
Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species.
Kurt A. Zimmerman, Melissa R. Bentley, Jeremie M. P. Lever, Zhang Li +7 more
2019Journal of the American Society of Nephrology154 citations Open access
Semantic Scholar
Potentially modifiable factors affecting the progression of autosomal dominant polycystic kidney disease.
V. Torres, J. Grantham, A. Chapman, M. Mrug +10 more
2011American Society of Nephrology. Clinical Journal152 citations Open access
Semantic Scholar
Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.
Sarah R. Senum, Ying Li, K. Benson, G. Joli +24 more
2021American Journal of Human Genetics150 citations Open access
Semantic Scholar
A comparison of ultrasound and magnetic resonance imaging shows kidney length predicts chronic kidney disease in autosomal dominant polycystic kidney disease
Harpreet Bhutani, V. Smith, F. Rahbari-Oskoui, A. Mittal +10 more
2015Kidney International117 citations Open access
Semantic Scholar
Resident macrophages reprogram toward a developmental state after acute kidney injury.
Jeremie M. P. Lever, T. Hull, Ravindra Boddu, Mark E. Pepin +17 more
2019JCI Insight106 citations Open access
Semantic Scholar
Baseline total kidney volume and the rate of kidney growth are associated with chronic kidney disease progression in Autosomal Dominant Polycystic Kidney Disease
Alan S. L. Yu, Cheng-Li Shen, D. Landsittel, P. Harris +8 more
2017Kidney International95 citations Open access
Semantic Scholar
Long-term trajectory of kidney function in autosomal dominant polycystic kidney disease
Alan S. L. Yu, Cheng-Li Shen, D. Landsittel, J. Grantham +9 more
2019Kidney International85 citations Open access
Semantic Scholar
Crystal deposition triggers tubule dilation that accelerates cystogenesis in polycystic kidney disease.
Jacob A Torres, M. Rezaei, Caroline Broderick, Louis Lin +9 more
2019Journal of Clinical Investigation79 citations Open access
Semantic Scholar
Urinary Proteomic Biomarkers for Diagnosis and Risk Stratification of Autosomal Dominant Polycystic Kidney Disease: A Multicentric Study
A. Kistler, A. Serra, J. Siwy, Diane Poster +10 more
2013PLoS ONE78 citations Open access
Semantic Scholar
The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.
S. Lavu, Lisa E. Vaughan, Sarah R. Senum, T. Kline +13 more
2020JCI Insight77 citations Open access
Semantic Scholar
Image texture features predict renal function decline in patients with Autosomal Dominant Polycystic Kidney Disease
T. Kline, P. Korfiatis, Marie E. Edwards, K. Bae +10 more
2017Kidney International73 citations Open access
Semantic Scholar
Tissue-Resident Macrophages Promote Renal Cystic Disease.
Kurt A. Zimmerman, C. Song, Zhang Li, Jeremie M. P. Lever +14 more
2019Journal of the American Society of Nephrology71 citations Open access
Semantic Scholar
Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse.
M. Mrug, Ren-Hua Li, Xiangqin Cui, T. Schoeb +2 more
2005Journal of the American Society of Nephrology66 citations
Semantic Scholar
Novel Approach to Estimate Kidney and Cyst Volumes using Mid-Slice Magnetic Resonance Images in Polycystic Kidney Disease
K. Bae, C. Tao, Jin-Hong Wang, D. Kaya +9 more
2013American Journal of Nephrology64 citations Open access
Semantic Scholar
Hemothorax and retroperitoneal hematoma after anticoagulation with enoxaparin.
M. Mrug, Prashant V. Mishra, Henry C. Lusane, J. Cunningham +1 more
2002Southern medical journal (Birmingham, Ala. Print)62 citations
Semantic Scholar
Identification of highly polymorphic microsatellites in the rhesus macaque Macaca mulatta by cross‐species amplification
M. Kayser, H. Ritter, F. Bercovitch, M. Mrug +2 more
1996Molecular Ecology52 citations
Semantic Scholar
Segmentation of individual renal cysts from MR images in patients with autosomal dominant polycystic kidney disease.
Kyungsoo Bae, Bumwoo Park, Hong-Liang Sun, Jin-Hong Wang +9 more
2013American Society of Nephrology. Clinical Journal51 citations Open access
Semantic Scholar
ROLE OF CHEMOKINES, INNATE AND ADAPTIVE IMMUNITY
Kurt A. Zimmerman, Katharina Hopp, M. Mrug
2020Cellular Signalling50 citations Open access
Semantic Scholar
Renal CD14 expression correlates with the progression of cystic kidney disease
Juling Zhou, Xiao-Sen Ouyang, Xiangqin Cui, T. Schoeb +5 more
2010Kidney International48 citations Open access
Semantic Scholar
Automated Segmentation of Kidneys from MR Images in Patients with Autosomal Dominant Polycystic Kidney Disease.
Youngwoo Kim, Ying-Hui Ge, C. Tao, Jianbing Zhu +8 more
2016American Society of Nephrology. Clinical Journal46 citations Open access
Semantic Scholar
Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption.
Neeraj Sharma, Erik B. Malarkey, N. Berbari, A. K. O’Connor +3 more
2013Journal of the American Society of Nephrology46 citations Open access
Semantic Scholar
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement.
Juling Zhou, Xiao-Sen Ouyang, T. Schoeb, Subhashini Bolisetty +6 more
2012Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
Genetic Testing for Chronic Kidney Diseases: Clinical Utility and Barriers Perceived by Nephrologists
M. Mrug, Michelle S. Bloom, C. Seto, M. Malhotra +5 more
2021Kidney Medicine43 citations Open access
Semantic Scholar
Validation of Endogenous Internal Real-Time PCR Controls in Renal Tissues
Xiangqin Cui, Juling Zhou, Jing Qiu, Martin R. Johnson +1 more
2009American Journal of Nephrology36 citations Open access
Semantic Scholar
The gene for autosomal dominant craniometaphyseal dysplasia maps to chromosome 5p and is distinct from the growth hormone-receptor gene.
P. Nürnberg, S. Tinschert, M. Mrug, Jochen Hampe +4 more
1997American Journal of Human Genetics35 citations Open access
Semantic Scholar
Impact of ultrasound-guided kidney biopsy simulation on trainee confidence and biopsy outcomes
Dalia Dawoud, W. Lyndon, S. Mrug, J. Bissler +1 more
2012American Journal of Nephrology33 citations Open access
Semantic Scholar
Blood-Borne Stem Cells Differentiate into Vascular and Cardiac Lineages During Normal Development
Ning Zhang, Deanna Mustin, Wade Reardon, Angela de Almeida +4 more
2006Stem Cells and Development33 citations
Semantic Scholar
Growth Pattern of Kidney Cyst Number and Volume in Autosomal Dominant Polycystic Kidney Disease.
K. Bae, Wen Zhou, Cheng-Li Shen, D. Landsittel +8 more
2019American Society of Nephrology. Clinical Journal31 citations Open access
Semantic Scholar
Utility of new image-derived biomarkers for autosomal dominant polycystic kidney disease prognosis using automated instance cyst segmentation.
Adriana V. Gregory, F. Chebib, Bhavya Poudyal, Heather Holmes +11 more
2023Kidney International29 citations Open access
Semantic Scholar
Polycystic Kidney Disease Diet: What Is Known and What Is Safe.
F. Chebib, K. Nowak, M. Chonchol, Kristen Bing +4 more
2023American Society of Nephrology. Clinical Journal28 citations
Semantic Scholar
Urinary T cells correlate with rate of renal function loss in autosomal dominant polycystic kidney disease
Kurt A. Zimmerman, Nancy M. Gonzalez, P. Chumley, Teresa Chacana +3 more
2019Physiological Reports28 citations Open access
Semantic Scholar
Simulation of real-time ultrasound-guided renal biopsy
M. Mrug, J. Bissler
2010Kidney International27 citations Open access
Semantic Scholar
Innovations in studying in vivo cell behavior and pharmacology in complex tissues – microvascular endothelial cells in the spotlight
Elise Langenkamp, J. Kamps, M. Mrug, E. Verpoorte +5 more
2013Cell and Tissue Research26 citations
Semantic Scholar
Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease
Kurt A. Zimmerman, Ji-Feng Huang, Lan He, Dustin Z. Revell +9 more
2020Kidney36025 citations Open access
Semantic Scholar
Sodium and potassium excretion predict increased depression in urban adolescents
S. Mrug, Catheryn A. Orihuela, M. Mrug, P. Sanders
2019Physiological Reports22 citations Open access
Semantic Scholar
Red blood cell exosome hemoglobin content increases after cardiopulmonary bypass and mediates acute kidney injury in an animal model.
Betty Pat, Joo-Yeun Oh, Juan Xavier Masjoan Juncos, P. Powell +12 more
2020Journal of Thoracic and Cardiovascular Surgery21 citations Open access
Semantic Scholar
Truncating PKHD1 and PKD2 mutations alter energy metabolism.
P. Chumley, Juling Zhou, S. Mrug, B. Chacko +10 more
2019AJP - Renal Physiology20 citations Open access
Semantic Scholar
Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney.
Shan Dan, G. Rezonzew, S. Mullen, Ronald Roye +12 more
2019AJP - Renal Physiology20 citations Open access
Semantic Scholar
Mks6 mutations reveal tissue‐ and cell type‐specific roles for the cilia transition zone
Wesley R. Lewis, Katie L. Bales, Dustin Z. Revell, Mandy J. Croyle +13 more
2018The FASEB Journal20 citations Open access
Semantic Scholar
Angiotensin II receptor type 1 expression in erythroid progenitors: Implications for the pathogenesis of postrenal transplant erythrocytosis.
M. Mrug, B. Julian, J. Prchal
2004Seminars in Nephrology20 citations
Semantic Scholar
Novel Methodology to Evaluate Renal Cysts in Polycystic Kidney Disease
K. Bae, Hong-Liang Sun, June-Goo Lee, Kyungsoo Bae +9 more
2014American Journal of Nephrology19 citations Open access
Semantic Scholar
Cx3cr1 controls kidney resident macrophage heterogeneity
A. Yashchenko, Sarah J. Bland, C. Song, Ummey Khalecha Bintha Ahmed +21 more
2023Frontiers in Immunology18 citations Open access
Semantic Scholar

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