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J. Hurley · SciRah

Researcher profile · Semantic Scholar

J. Hurley

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J. Hurley — researcher profile on SciRah

h-index: 63
Works: 212
Citations: 12K

Most-cited papers

Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye
Mark A. Kanow, Michelle M. Giarmarco, Connor S. R. Jankowski, Kristine A. Tsantilas +13 more
2017bioRxiv335 citations Open access
Semantic Scholar
Deregulated Myc Requires MondoA/Mlx for Metabolic Reprogramming and Tumorigenesis
P. Carroll, Daniel Diolaiti, Lisa G. McFerrin, Hai-Wei Gu +9 more
2015Cancer Cell194 citations Open access
Semantic Scholar
Retina Metabolism and Metabolism in the Pigmented Epithelium: A Busy Intersection
J. Hurley
2021Annual Review of Vision Science166 citations Open access
Semantic Scholar
Regulation of Arrestin Binding by Rhodopsin Phosphorylation Level*
S. Vishnivetskiy, D. Raman, J. Wei, Matthew J. Kennedy +2 more
2007Journal of Biological Chemistry155 citations Open access
Semantic Scholar
The Retinal Pigment Epithelium Utilizes Fatty Acids for Ketogenesis
J. Adijanto, Jian-Hai Du, C. Moffat, E. Seifert +2 more
2014Journal of Biological Chemistry146 citations Open access
Semantic Scholar
CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense non-coding RNA
B. Sopher, Paula D. Ladd, Victor V. Pineda, R. Libby +6 more
2011Neuron133 citations Open access
Semantic Scholar
Flow of energy in the outer retina in darkness and in light
J. Linton, Lars C. Holzhausen, N. Babai, H. Song +25 more
2010Proceedings of the National Academy of Sciences of the United States of America128 citations Open access
Semantic Scholar
Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina
Ken J. Lindsay, Jian-Hai Du, Stephanie R. Sloat, Laura Contreras +5 more
2014Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium
Jian-Hai Du, Aya Yanagida, Kaitlen Knight, Abbi L. Engel +8 more
2016Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
NaV1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms
Sung Han, Frank H. Yu, Michael D. Schwartz, J. Linton +4 more
2012Proceedings of the National Academy of Sciences of the United States of America102 citations Open access
Semantic Scholar
Loss of MPC1 reprograms retinal metabolism to impair visual function
Allison Grenell, Ye-Kai Wang, Michelle Yam, Aditi Swarup +15 more
2019Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina*
Jian-Hai Du, Austin M. Rountree, W. Cleghorn, Laura Contreras +11 more
2015Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side
Jennifer R. Chao, Kaitlen Knight, Abbi L. Engel, Connor S. R. Jankowski +7 more
2017Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration.
Lijuan Zhang, Jian-Hai Du, Sally Justus, Chun-Wei Hsu +11 more
2016Journal of Clinical Investigation88 citations Open access
Semantic Scholar
Identification of a zebrafish cone photoreceptor-specific promoter and genetic rescue of achromatopsia in the nof mutant.
Breandán N. Kennedy, Yolanda Alvarez, Susan E. Brockerhoff, G. Stearns +3 more
2007Investigative Ophthalmology and Visual Science87 citations
Semantic Scholar
Inhibition of Mitochondrial Pyruvate Transport by Zaprinast Causes Massive Accumulation of Aspartate at the Expense of Glutamate in the Retina*
Jian-Hai Du, W. Cleghorn, Laura Contreras, Ken J. Lindsay +10 more
2013Journal of Biological Chemistry85 citations Open access
Semantic Scholar
Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium
Celia M. Bisbach, Daniel T. Hass, Brian M. Robbings, Austin M. Rountree +3 more
2020bioRxiv83 citations Open access
Semantic Scholar
Roles of Glucose in Photoreceptor Survival*
Andrei O. Chertov, Lars C. Holzhausen, Iok Teng Kuok, Drew Couron +5 more
2011Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Subunit Dissociation and Diffusion Determine the Subcellular Localization of Rod and Cone Transducins
Derek H. Rosenzweig, K. Nair, J. Wei, Qiang Wang +8 more
2007Journal of Neuroscience71 citations Open access
Semantic Scholar
AIPL1, a Protein Associated with Childhood Blindness, Interacts with α-Subunit of Rod Phosphodiesterase (PDE6) and Is Essential for Its Proper Assembly*
Saravanan Kolandaivelu, Jing Huang, J. Hurley, Visvanathan Ramamurthy
2009Journal of Biological Chemistry70 citations Open access
Semantic Scholar
Probing Metabolism in the Intact Retina Using Stable Isotope Tracers
Jian-Hai Du, J. Linton, J. Hurley
2015Methods in Enzymology68 citations Open access
Semantic Scholar
The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
Monica Sanchez-Contreras, Mariya T. Sweetwyne, Kristine A. Tsantilas, Jeremy A. Whitson +10 more
2022bioRxiv64 citations Open access
Semantic Scholar
Cytosolic reducing power preserves glutamate in retina
Jian-Hai Du, W. Cleghorn, Laura Contreras, J. Linton +7 more
2013Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
Pyruvate kinase M2 regulates photoreceptor structure, function, and viability
A. Rajala, Yuhong Wang, R. Brush, Kristine A. Tsantilas +6 more
2018Cell Death and Disease53 citations Open access
Semantic Scholar
Daily mitochondrial dynamics in cone photoreceptors
Michelle M. Giarmarco, Daniel C. Brock, Brian M. Robbings, W. Cleghorn +7 more
2020Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Relationships between visual cycle retinoids, rhodopsin phosphorylation and phototransduction in mouse eyes during light and dark-adaptation
Kimberly A. Lee, Maria Nawrot, G. Garwin, J. C. Saari +1 more
2010Biochemistry42 citations Open access
Semantic Scholar
Optimal processing of photoreceptor signals is required to maximize behavioural sensitivity
Haruhisa Okawa, K. Miyagishima, A. C. Arman, J. Hurley +2 more
2010Journal of Physiology40 citations Open access
Semantic Scholar
Mitochondria Maintain Distinct Ca2+ Pools in Cone Photoreceptors
Michelle M. Giarmarco, W. Cleghorn, Stephanie R. Sloat, J. Hurley +1 more
2017Journal of Neuroscience38 citations Open access
Semantic Scholar
Arrestin Competition Influences the Kinetics and Variability of the Mammalian Rod's Single-Photon Responses
T. Doan, Anthony W. Azevedo, J. Hurley, F. Rieke
2009Journal of Neuroscience37 citations Open access
Semantic Scholar
Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria
Celia M. Bisbach, Rachel A. Hutto, D. Poria, W. Cleghorn +5 more
2020Scientific Reports32 citations Open access
Semantic Scholar
Increasing Ca2+ in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress
Rachel A. Hutto, Celia M. Bisbach, Fatima Abbas, Daniel C. Brock +7 more
2019Cell Death and Differentiation32 citations Open access
Semantic Scholar
Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
Celia M. Bisbach, Daniel T. Hass, E. Thomas, Timothy J. Cherry +1 more
2022Investigative Ophthalmology and Visual Science30 citations Open access
Semantic Scholar
Impact of euthanasia, dissection and postmortem delay on metabolic profile in mouse retina and RPE/choroid
Si-Yan Zhu, Michelle Yam, Ye-Kai Wang, J. Linton +3 more
2018Experimental Eye Research30 citations Open access
Semantic Scholar
Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis
Daniel T. Hass, Celia M. Bisbach, Brian M. Robbings, M. Sadilek +2 more
2022Cell Reports28 citations Open access
Semantic Scholar
Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision
R. Ward, J. Kaylor, D. Cobice, Dionissia A Pepe +5 more
2020Journal of Biological Chemistry25 citations Open access
Semantic Scholar
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice
Kristine A. Tsantilas, W. Cleghorn, Celia M. Bisbach, Jeremy A. Whitson +14 more
2021Investigative Ophthalmology and Visual Science21 citations Open access
Semantic Scholar
Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health
Wei-Yong Shen, Sora Lee, A. E. Mathai, Rui Zhang +11 more
2021Glia20 citations Open access
Semantic Scholar
Deficient glucose and glutamine metabolism in Aralar/AGC1/Slc25a12 knockout mice contributes to altered visual function
Laura Contreras, L. Ramírez, Jian-Hai Du, J. Hurley +2 more
2016Molecular Vision19 citations
Semantic Scholar
Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium
Abbi L. Engel, Ye-Kai Wang, Thomas H. Khuu, E. Worrall +13 more
2021bioRxiv17 citations Open access
Semantic Scholar
How Excessive cGMP Impacts Metabolic Proteins in Retinas at the Onset of Degeneration
Jian-Hai Du, J. An, J. Linton, Ye-Kai Wang +1 more
2018Advances in Experimental Medicine and Biology14 citations Open access
Semantic Scholar
Mitochondria: The Retina's Achilles' Heel in AMD.
D. Ferrington, M. C. Kenney, Shari R. Atilano, J. Hurley +2 more
2021Advances in Experimental Medicine and Biology13 citations
Semantic Scholar
Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers
B. Berkowitz, R. Podolsky, K. Childers, Robin L. Roberts +10 more
2022Investigative Ophthalmology and Visual Science12 citations Open access
Semantic Scholar
Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration
Tirthankar Sinha, Jian-Hai Du, Mustafa S. Makia, J. Hurley +2 more
2021Proceedings of the National Academy of Sciences of the United States of America12 citations Open access
Semantic Scholar
Energy Metabolism in the Vertebrate Retina
J. Hurley, Andrei O. Chertov, Ken J. Lindsay, Michelle Giamarco +3 more
20149 citations
Semantic Scholar
In vivo exchange of glucose and lactate between photoreceptors and the retinal pigment epithelium
Daniel T. Hass, Elizabeth Giering, J. Y. Han, Celia M. Bisbach +8 more
2024bioRxiv8 citations Open access
Semantic Scholar
Fluidics system for resolving concentration-dependent effects of dissolved gases on tissue metabolism
Varun Kamat, Brian M. Robbings, Seung-Ryoung Jung, J. Kelly +3 more
2021bioRxiv7 citations Open access
Semantic Scholar
It's never too late to save a photoreceptor.
J. Hurley, Jennifer R. Chao
2015Journal of Clinical Investigation7 citations Open access
Semantic Scholar
Preparing Fresh Retinal Slices from Adult Zebrafish for Ex Vivo Imaging Experiments.
Michelle M. Giarmarco, W. Cleghorn, J. Hurley, Susan E. Brockerhoff
2018Journal of Visualized Experiments5 citations Open access
Semantic Scholar
Calcium uptake by mitochondria is required to maintain distinct Ca2+ pools in cone photoreceptors
W. Cleghorn, Michelle M. Giarmarco, J. Hurley, Susan E. Brockerhoff
20165 citations
Semantic Scholar
PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors
M. Morrissey, Sara Shelton, Susan E. Brockerhoff, J. Hurley +1 more
2011BMC Developmental Biology5 citations Open access
Semantic Scholar

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J. Linton×12
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Susan E. Brockerhoff×11
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M. Sadilek — researcher profile on SciRah

Ken J. Lindsay×7

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Celia M. Bisbach×7

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Celia M. Bisbach — researcher profile on SciRah

Brian M. Robbings×7

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Daniel T. Hass×6

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Daniel T. Hass — researcher profile on SciRah

Michelle M. Giarmarco×5

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Michelle M. Giarmarco — researcher profile on SciRah

Connor S. R. Jankowski×5

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