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C. Moffat · SciRah

Researcher profile · Semantic Scholar

C. Moffat

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C. Moffat — researcher profile on SciRah

h-index: 15
Works: 36
Citations: 2,560

Most-cited papers

MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca2+ uniporter
G. Csordás, Tünde Golenár, E. Seifert, K. Kamer +10 more
2013Cell Metabolism478 citations Open access
Semantic Scholar
SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
Gino Boily, E. Seifert, Lisa Bevilacqua, Xiao-Hong He +10 more
2008PLoS ONE477 citations Open access
Semantic Scholar
Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells
C. Aguer, Daniela Gambarotta, R. Mailloux, C. Moffat +3 more
2011PLoS ONE287 citations Open access
Semantic Scholar
Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress
M. Picard, Meagan J. McManus, J. Gray, C. Nasca +5 more
2015Proceedings of the National Academy of Sciences of the United States of America286 citations Open access
Semantic Scholar
MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration
A. Antony, M. Paillard, C. Moffat, Egle Juskeviciute +7 more
2016Nature Communications192 citations Open access
Semantic Scholar
Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
M. Paillard, G. Csordás, G. Szanda, Tünde Golenár +7 more
2017Cell Reports177 citations Open access
Semantic Scholar
The Retinal Pigment Epithelium Utilizes Fatty Acids for Ketogenesis
J. Adijanto, Jian-Hai Du, C. Moffat, E. Seifert +2 more
2014Journal of Biological Chemistry146 citations Open access
Semantic Scholar
MICU 1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca 2 + Uniporter
G. Csordás, Tünde Golenár, Erin L. Seifert, K. Kamer +10 more
2013137 citations
Semantic Scholar
Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
Mahsa Zarei, Shruti Lal, Seth J. Parker, A. Nevler +15 more
2017Cancer Research97 citations Open access
Semantic Scholar
Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver[S]
C. Moffat, L. Bhatia, Teresa Nguyen, P. Lynch +7 more
2014Journal of Lipid Research78 citations Open access
Semantic Scholar
Functional mitochondrial analysis in acute brain sections from adult rats reveals mitochondrial dysfunction in a rat model of migraine.
Nathan T. Fried, C. Moffat, E. Seifert, M. Oshinsky
2014American Journal of Physiology - Cell Physiology50 citations Open access
Semantic Scholar
Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform.
E. Seifert, M. Bastianelli, C. Aguer, C. Moffat +4 more
2012Journal of applied physiology37 citations Open access
Semantic Scholar
Metabolic functions of AMPK: Aspects of structure and of natural mutations in the regulatory gamma subunits
C. Moffat, Mary Ellen Harper
2010IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology34 citations Open access
Semantic Scholar
IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.
E. Loro, E. Seifert, C. Moffat, Freddy Romero +7 more
2015American Journal of Physiology. Regulatory Integrative and Comparative Physiology31 citations Open access
Semantic Scholar
Increased proton leak and SOD2 expression in myotubes from obese non-diabetic subjects with a family history of type 2 diabetes.
C. Aguer, M. Pasqua, A. B. Thrush, C. Moffat +7 more
2013Biochimica et Biophysica Acta23 citations Open access
Semantic Scholar
Natural and Induced Mitochondrial Phosphate Carrier Loss
E. Seifert, A. Gál, M. Acoba, Qi-Pei Li +6 more
2016Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response
Carmen Estey, E. Seifert, C. Aguer, C. Moffat +1 more
2012Experimental Gerontology14 citations Open access
Semantic Scholar
MICU1 Regulation of Mitochondrial Calcium Uptake is Crucial for Liver Regeneration
A. Antony, M. Paillard, C. Moffat, Egle Juskeviciute +5 more
20161 citations Open access
Semantic Scholar
Mitochondrial functions modulate the stress response in mice.
M. Picard, Meagan J. McManus, J. Gray, C. Nasca +5 more
2015Psychoneuroendocrinology1 citations
Semantic Scholar
Control of Mitochondrial Ca2+ Uptake Threshold via the Micu1:Mcu Ratio
Tünde Golenár, G. Csordás, G. Szanda, C. Moffat +3 more
20141 citations Open access
Semantic Scholar
Metabolic Coupling Between the Retinal Pigment Epithelium (RPE) and Retina
J. Adijanto, E. Seifert, C. Moffat, A. Maminishkis +1 more
20131 citations
Semantic Scholar
Correction: Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells
C. Aguer, Daniela Gambarotta, R. Mailloux, C. Moffat +3 more
2012PLoS ONE1 citations Open access
Semantic Scholar
Correction: Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells
C. Aguer, Daniela Gambarotta, R. Mailloux, C. Moffat +3 more
2012PLoS ONE1 citations Open access
Semantic Scholar
3-7-2017 Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca ( 2 + ) Signals Is Controlled by the Stoichiometry of MICU 1 / 2 and MCU
M. Paillard, G. Csordás, G. Szanda, Tünde Golenár +7 more
20180 citations
Semantic Scholar
Dependence of mitochondrial Ca2 + uptake on the molecular composition of the uniporter
G. Hajnóczky, M. Paillard, G. Csordás, Valentina Debattisti +3 more
20160 citations Open access
Semantic Scholar
MICU1, the Ca2+ Sensing Regulator of the Mitochondrial Ca2+ Uniporter is Required for Adaptation to Postnatal Life
M. Paillard, A. Antony, C. Moffat, Egle Juskeviciute +6 more
20160 citations Open access
Semantic Scholar
Novel Mutations in SLC25A3 Encoding the Mitochondrial Phosphate Carrier
E. Seifert, A. Gál, M. Acoba, S. Claypool +6 more
20150 citations Open access
Semantic Scholar
isoformwithout major shifts in myosin heavy chain emission 2 O 2 inherent mitochondrial oxidative and H Intrinsic aerobic capacity correlates with greater
L. Koch, S. Britton, M. Harper, E. Seifert +9 more
20150 citations
Semantic Scholar
The Stoichiometry between MICU1 and MCU Determines the Different Mitochondrial Ca2+ Uptake Phenotypes in Heart and Liver
M. Paillard, G. Csordás, Tünde Golenár, C. Moffat +2 more
20150 citations Open access
Semantic Scholar
MICU1-dependent Threshold and Cooperativity of Mitochondrial Ca2+ Uptake in the Liver
G. Csordás, E. Seifert, Tünde Golenár, C. Moffat +6 more
20130 citations Open access
Semantic Scholar
Mouse embryonic fibroblasts devoid of both mitofusin1 and mitofusin2 can acutely shift from glycolytic to oxidative metabolism.
E. Seifert, C. Moffat, Ewa Strus
20130 citations Open access
Semantic Scholar
Substrate Oxidation Control of Respiratory Rates in Primary Hepatocytes
A. Antony, C. Moffat, Aditi Swarup, E. Seifert +1 more
20130 citations Open access
Semantic Scholar
Reprogramming of Mitochondrial Ca2+ Handling in MICU1-Deficient HeLa Cells
Tünde Golenár, G. Csordás, E. Seifert, C. Moffat +5 more
20130 citations Open access
Semantic Scholar
Changes in Mitochondrial Oxygen Consumption can Associate with Increases in Total Mitochondrial Calcium
E. Seifert, G. Csordás, Tünde Golenár, C. Moffat +3 more
20120 citations Open access
Semantic Scholar
178 Abnormal Neonate Cardiomyocyte Metabolism is Associated with Alterations in Adult Cardiac Metabolism in a Mouse Model of the Arg302gln-prkag2 Cardiac Syndrome
Stephanie L. Thorn, J. DaSilva, R. deKemp, C. Moffat +5 more
20110 citations
Semantic Scholar
Impact of the AMPK gamma2 R302Q Mutation on Human Skeletal Muscle Metabolism
C. Moffat
20100 citations
Semantic Scholar

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