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I. Jacobs · SciRah

Researcher profile · Semantic Scholar

I. Jacobs

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I. Jacobs — researcher profile on SciRah

h-index: 15
Works: 40
Citations: 921

Most-cited papers

Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial.
E. Santagostino, U. Martinowitz, T. Lissitchkov, Brigitte Pan-Petesch +13 more
2016Blood207 citations Open access
Semantic Scholar
Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients.
E. Santagostino, C. Négrier, R. Klamroth, A. Tiede +4 more
2012Blood133 citations Open access
Semantic Scholar
Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
T. Craig, A. Reshef, H. Li, J. Jacobs +21 more
2023The Lancet89 citations Open access
Semantic Scholar
Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks.
T. Craig, B. Zuraw, H. Longhurst, M. Cicardi +36 more
2019Journal of Allergy and Clinical Immunology: In Practice75 citations Open access
Semantic Scholar
Long-Acting Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Children
G. Kenet, H. Chambost, C. Male, T. Lambert +8 more
2016Thrombosis and Haemostasis59 citations Open access
Semantic Scholar
Prophylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial.
T. Craig, M. Magerl, D. Levy, A. Reshef +13 more
2022The Lancet51 citations
Semantic Scholar
Assessment of nicotinic acetylcholine receptor-mediated release of [(3)H]-norepinephrine from rat brain slices using a new 96-well format assay.
David J. Anderson, P. Puttfarcken, I. Jacobs, C. Faltynek
2000Neuropharmacology46 citations
Semantic Scholar
Characterization of nicotinic acetylcholine receptor-mediated [(3)H]-dopamine release from rat cortex and striatum.
P. Puttfarcken, I. Jacobs, C. Faltynek
2000Neuropharmacology43 citations
Semantic Scholar
Results of a phase I/II open-label, safety and efficacy trial of coagulation factor IX (recombinant), albumin fusion protein in haemophilia B patients
U. Martinowitz, T. Lissitchkov, A. Lubetsky, G. Jotov +5 more
2015Haemophilia39 citations Open access
Semantic Scholar
Differential regulation of nicotinic receptor-mediated neurotransmitter release following chronic (-)-nicotine administration.
I. Jacobs, David J. Anderson, C. Surowy, P. Puttfarcken
2002Neuropharmacology35 citations
Semantic Scholar
Population pharmacokinetics of a new long‐acting recombinant coagulation factor IX albumin fusion protein for patients with severe hemophilia B
Ying Zhang, J. Roberts, Debra M. Bensen-Kennedy, I. Jacobs +5 more
2016Journal of Thrombosis and Haemostasis30 citations Open access
Semantic Scholar
Efficacy and safety of long‐acting recombinant fusion protein linking factor IX with albumin in haemophilia B patients undergoing surgery
C. Négrier, F. Karim, L. M. Lepatan, A. Lienhart +8 more
2016Haemophilia26 citations Open access
Semantic Scholar
Garadacimab for hereditary angioedema attack prevention: long-term efficacy, quality of life, and safety data from a phase 2, randomised, open-label extension study.
T. Craig, D. Levy, A. Reshef, W. Lumry +12 more
2024The Lancet Haematology18 citations
Semantic Scholar
Long-term Safety and Efficacy of Subcutaneous C1-Inhibitor in Older Patients With Hereditary Angioedema.
J. Bernstein, L. Schwartz, William H. Yang, James R. Baker +8 more
2020Annals of Allergy, Asthma & Immunology15 citations Open access
Semantic Scholar
Subcutaneous C1-esterase inhibitor to prevent hereditary angioedema attacks: Safety findings from the COMPACT trial.
H. Li, Sarah Mycroft, S. Christiansen, Daniel N. Wood +3 more
2018Allergy and Asthma Proceedings15 citations
Semantic Scholar
Treatment effect of switching from intravenous to subcutaneous C1-inhibitor for prevention of hereditary angioedema attacks: COMPACT subgroup findings.
T. Craig, W. Lumry, M. Cicardi, B. Zuraw +13 more
2019Journal of Allergy and Clinical Immunology: In Practice14 citations Open access
Semantic Scholar
Pharmacokinetic Results of Two Phase III Clinical Studies of Coagulation Factor IX (Recombinant) Albumin Fusion Protein (rIX-FP) in Previously Treated Patients with Hemophilia B (PROLONG-9FP)
E. Santagostino, I. Jacobs, C. Voigt, A. Feussner +1 more
20149 citations
Semantic Scholar
Efficacy, PK and Safety Results of Clinical Study Of Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) In Previously Treated Patients With Hemophilia B
A. Lubetsky, T. Lissitchkov, E. Santagostino, G. Jotov +5 more
20137 citations
Semantic Scholar
Efficacy, PK and Safety Results of a Phase I/II Clinical Trial of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Treated Patients with Haemophilia B (PROLONG - 9FP)
U. Martinowitz, A. Lubetsky, E. Santagostino, G. Jotov +7 more
20126 citations
Semantic Scholar
Efficacy, pharmacokinetics, and safety of subcutaneous C1-esterase inhibitor as prophylaxis in Japanese patients with hereditary angioedema: Results of a Phase 3 study.
T. Fukuda, K. Yamagami, K. Kawahata, Yuzo Suzuki +8 more
2023Allergology International3 citations Open access
Semantic Scholar
Population pharmacokinetic model for a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients
R. Parasrampuria, R. Easton, Z. Yao, D. Bensen-Kennedy +3 more
20152 citations
Semantic Scholar
Response to Subcutaneous C1-Esterase Inhibitor (C1-INH [SC]), a Prophylactic Treatment for Adolescents and Adults with Hereditary Angioedema: Results From the Phase 3 COMPACT Trial
R. Gower, H. Li, D. Levy, I. Jacobs
20181 citations
Semantic Scholar
Pharmacokinetic Profile of Subcutaneous C1-Esterase Inhibitor (C1-INH [SC]) in Adolescent and Adult Patients with Hereditary Angioedema (HAE)
Dipti K. Pawaskar, I. Jacobs, I. Pragst, H. Feuersenger
2018Pediatrics1 citations Open access
Semantic Scholar
Prevention of Attacks of Hereditary Angioedema (HAE) with Subcutaneous C1-Esterase Inhibitor (C1-INH [SC]) by Anatomical Location: Results From the Phase III COMPACT Study (NCT01912456)
D. Levy, J. Chiao, H. Feuersenger, T. Craig +4 more
20181 citations Open access
Semantic Scholar
LONG-TERM EFFICACY AND SAFETY OF SUBCUTANEOUS C1-INHIBITOR IN ELDERLY PATIENTS WITH HEREDITARY ANGIOEDEMA TYPE I/II
J. Bernstein, L. Schwartz, H. Feuersenger, I. Pragst +2 more
2018Annals of Allergy, Asthma & Immunology1 citations
Semantic Scholar
EXPLORATORY ANALYSIS REVEALS POSITIVE CORRELATION BETWEEN C1 ESTERASE INHIBITOR AND SERUM COMPLEMENT 4 ANTIGEN LEVELS
B. Zuraw, I. Jacobs, I. Pragst, H. Feuersenger +3 more
2018Annals of Allergy, Asthma & Immunology1 citations
Semantic Scholar
Placebo-Controlled Trials of C1-Inhibitor (C1-INH) Replacement Therapy for Routine Prevention of Attacks in Patients with Hereditary Angioedema (HAE)
J. Bernstein, H. Li, T. Craig, H. Longhurst +6 more
20171 citations Open access
Semantic Scholar
Efficacy and Safety Results of Prolong-9FP Clinical Program of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Treated Patients with Hemophilia B
E. Santagostino, C. Voigt, D. Wolko, G. Cole +2 more
20151 citations
Semantic Scholar
Garadacimab for the prevention of hereditary angioedema attacks: a plain language summary of the VANGUARD study
Timothy J. Craig, A. Reshef, H. H. Li, J. Jacobs +21 more
2023Future Rare Diseases0 citations Open access
Semantic Scholar
Efficacy and Safety of Subcutaneous Garadacimab for the Prophylaxis of Hereditary Angioedema Attacks in Adults and Adolescent Patients with HAE: Results from a Multicenter, Placebo-Controlled Phase 3 Trial
T. Craig, M. Magerl, A. Reshef, H. Li +21 more
2023Journal of Allergy and Clinical Immunology0 citations
Semantic Scholar
Taking the Skeletons Out of the Closet: Contested Authority and Human Remains Displays in the Anthropology Museum
I. Jacobs
20200 citations
Semantic Scholar
P160 LONG-TERM PROPHYLAXIS WITH SUBCUTANEOUS C1-INHIBITOR IN US PATIENTS WITH HEREDITARY ANGIOEDEMA AND VERY FREQUENT ATTACKS
T. Craig, B. Zuraw, M. Cicardi, H. Longhurst +3 more
2019Annals of Allergy, Asthma & Immunology0 citations
Semantic Scholar
Reduced D-dimer Levels In C1-esterase-inhibitor Hereditary Angioedema (C1-INH-HAE) Patients Treated With Subcutaneous C1-esterase-inhibitor (C1-INH[SC]): Findings From The COMPACT Study
A. Reshef, M. Cicardi, B. Zuraw, T. Craig +3 more
20180 citations Open access
Semantic Scholar
EFFECTS OF SUBCUTANEOUS C1-ESTERASE INHIBITOR ON COAGULATION AND FIBRINOLYTIC PARAMETERS
A. Reshef, D. Levy, B. Zuraw, H. Longhurst +9 more
2018Annals of Allergy, Asthma & Immunology0 citations
Semantic Scholar
Patients With Severe Hereditary Angioedema Treated With Subcutaneous C1-Esterase Inhibitor (C1-INH [SC]) to Reduce the Incidence and Severity of Attacks: Results From a Phase 3 Trial
R. Gower, Henry H. Li, D. Levy, I. Jacobs
2018Pediatrics0 citations
Semantic Scholar
OUTCOMES FOLLOWING USE OF SUBCUTANEOUS C1-INHIBITOR DURING PREGNANCY IN PATIENTS WITH HEREDITARY ANGIOEDEMA
D. Levy, A. Banerji, M. Cicardi, H. Feuersenger +3 more
2018Annals of Allergy, Asthma & Immunology0 citations
Semantic Scholar
Switch from Intravenous C1-Inhibitor C1-INH(IV) to Subcutaneous C1-Inhibitor [C1 INH(SC)] for Routine Prevention of Hereditary Angioedema (HAE) Attacks: Subgroup Findings from the Compact Trial
T. Craig, J. W. Baker, W. Lumry, H. Farkas +2 more
20170 citations Open access
Semantic Scholar
Bleeding Risk Reduction in Relation to Predicted Factor IX Levels in Hemophilia B Patients Receiving Idelvion (rIX-FP)
John Roberts, C. Fosser, M. Tortorici, A. Veldman +2 more
20160 citations Open access
Semantic Scholar
Efficacy and Safety of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Treated Patients with Hemophilia B Undergoing Major Orthopedic Surgeries
C. Négrier, Lynda Mae Lepatan, F. Karim, A. Lienhart +4 more
20150 citations
Semantic Scholar
Long-Term Use of Coagulation Factor IX (Recombinant) Albumin Fusion Protein (rIX-FP) in Previously Treated Patients with Hemophilia B in the Prolong-9FP Program
A. Lubetsky, U. Martinowitz, T. Lissitchkov, C. Voigt +3 more
20150 citations
Semantic Scholar

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