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M. Hughes · SciRah

Researcher profile · Semantic Scholar

M. Hughes

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M. Hughes — researcher profile on SciRah

h-index: 8
Works: 12
Citations: 2,825

Most-cited papers

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
E. Mills, D. Ryan, H. Prag, Dina Dikovskaya +31 more
2018Nature1,744 citations Open access
Semantic Scholar
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
A. Hooftman, Stefano Angiari, Svenja S. Hester, Sarah E. Corcoran +10 more
2020Cell Metabolism572 citations Open access
Semantic Scholar
Metabolic regulation of NLRP3
M. Hughes, L. O'Neill
2018Immunological Reviews268 citations Open access
Semantic Scholar
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
M. Hughes, A. Hooftman, Stefano Angiari, P. Tummala +19 more
2019Cell Reports83 citations Open access
Semantic Scholar
Caspase-11 promotes allergic airway inflammation
Z. Zaslona, E. Flis, Mieszko M. Wilk, R. Carroll +18 more
2020Nature Communications70 citations Open access
Semantic Scholar
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
Clíona Ní Cheallaigh, Frederick J. Sheedy, J. Harris, Natalia Muñoz‐Wolf +23 more
2016Immunity36 citations Open access
Semantic Scholar
Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling
M. Hughes, P. Lavrencic, R. Coll, T. Ve +8 more
2017Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages
M. Hughes, A. F. Mcgettrick, L. O'Neill
2017Microbiology spectrum29 citations
Semantic Scholar
Glutathione Transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation.
P. Tummala, M. Rooke, J. Dahlstrom, Shuhei Takahashi +5 more
2021Carcinogenesis6 citations
Semantic Scholar
An Analysis of Glutathionylation in the Modulation of the Critical Innate Immune Regulators Mal and NEK7
M. Hughes
20180 citations
Semantic Scholar
Electromagnetic Hypersensitivity as a Progressive Disease
M. Hughes
19990 citations
Semantic Scholar
Elastomeric compositions having improved abrasion resistance, coefficient of friction and green strengths
M. Hughes, K. Laughner, F. Martin, D. Parikh +1 more
19980 citations
Semantic Scholar

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L. O'Neill×9
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L. O'Neill — researcher profile on SciRah
A. F. Mcgettrick×4
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A. F. Mcgettrick — researcher profile on SciRah
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D. Ryan — researcher profile on SciRah
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Stefano Angiari — researcher profile on SciRah

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