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Y. Hayakawa · SciRah

Researcher profile · Semantic Scholar

Y. Hayakawa

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Y. Hayakawa — researcher profile on SciRah

h-index: 52
Works: 217
Citations: 9,965

Most-cited papers

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
Bernhard W. Renz, Ryota Takahashi, Takayuki Tanaka, M. Macchini +26 more
2018Cancer Cell477 citations Open access
Semantic Scholar
Tumor microenvironment in gastric cancers
Y. Oya, Y. Hayakawa, K. Koike
2020Cancer Science284 citations Open access
Semantic Scholar
Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness
Bernhard W. Renz, Takayuki Tanaka, Masaki Sunagawa, Ryota Takahashi +21 more
2018Cancer Discovery276 citations Open access
Semantic Scholar
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis
Edoardo Del Poggetto, Iwt Ho, C. Balestrieri, Er-Yen Yen +29 more
2021Science218 citations Open access
Semantic Scholar
The origin and contribution of cancer-associated fibroblasts in colorectal carcinogenesis
Hiroki Kobayashi, Krystyna A. Gieniec, Tamsin R. M. Lannagan, Tong-Tong Wang +33 more
2021Gastroenterology199 citations Open access
Semantic Scholar
The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis
Hiroki Kobayashi, Krystyna A. Gieniec, Josephine A. Wright, Tong-Tong Wang +32 more
2020Gastroenterology146 citations Open access
Semantic Scholar
PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric Tumorigenesis in Mice
Woosook Kim, Timothy H. Chu, H. Nienhüser, Zheng-Yu Jiang +8 more
2020Gastroenterology132 citations Open access
Semantic Scholar
Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis.
S. Imai, Takuya Ooki, N. Murata-Kamiya, Daisuke Komura +16 more
2021Cell Host and Microbe130 citations Open access
Semantic Scholar
Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis
S. Kawamura, Y. Matsushita, Shigeyuki Kurosaki, Mizuki Tange +22 more
2022Journal of Clinical Investigation105 citations Open access
Semantic Scholar
Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte–mediated immune suppression
Ryota Takahashi, M. Macchini, Masaki Sunagawa, Zheng-Yu Jiang +12 more
2020Gut84 citations
Semantic Scholar
Stem cell and cancer origin in the upper GI tract
Y. Hayakawa, H. Nakagawa, A. Rustgi, Jian-Wen Que +1 more
2021Cell Stem Cell78 citations Open access
Semantic Scholar
Plasticity of Intestinal Epithelium: Stem Cell Niches and Regulatory Signals
Ken Kurokawa, Y. Hayakawa, K. Koike
2020International Journal of Molecular Sciences62 citations Open access
Semantic Scholar
Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering−Nanoparticle Endoscopy
S. Harmsen, S. Rogalla, Ruimin Huang, M. Spaliviero +15 more
2019ACS Nano61 citations Open access
Semantic Scholar
F4/80+Ly6Chigh Macrophages Lead to Cell Plasticity and Cancer Initiation in Colitis
A. Shin, Yodit Tesfagiorgis, F. Larsen, M. Derouet +11 more
2023Gastroenterology59 citations Open access
Semantic Scholar
Long-term proton pump inhibitor use is a risk factor of gastric cancer after treatment for Helicobacter pylori: a retrospective cohort analysis
R. Niikura, Y. Hayakawa, Y. Hirata, Atsuo Yamada +2 more
2017Gut59 citations
Semantic Scholar
Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
M. Middelhoff, H. Nienhüser, G. Valenti, H. C. Maurer +12 more
2020Nature Communications56 citations Open access
Semantic Scholar
Artificial intelligence versus expert endoscopists for diagnosis of gastric cancer in patients who have undergone upper gastrointestinal endoscopy
R. Niikura, Tomonori Aoki, S. Shichijo, Atsuo Yamada +10 more
2021Endoscopy54 citations Open access
Semantic Scholar
GPR30-expressing Gastric Chief Cells do not Dedifferentiate but are Eliminated via PDK-dependent Cell Competition During Development of Metaplasia
M. Hata, Hiroto Kinoshita, Y. Hayakawa, Mitsuru Konishi +15 more
2020Gastroenterology53 citations Open access
Semantic Scholar
Machine learning-based personalised prediction of gastric cancer incidence using the endoscopic and histological findings at the initial endoscopy.
J. Arai, Tomonori Aoki, Masaya Sato, R. Niikura +8 more
2022Gastrointestinal Endoscopy51 citations Open access
Semantic Scholar
Hormonal suppression of stem cells inhibits symmetric cell division and gastric tumorigenesis
W. Chang, Hongshan Wang, Woosook Kim, Yang Liu +12 more
2020Cell Stem Cell50 citations Open access
Semantic Scholar
BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice
Y. Hayakawa, Mayo Tsuboi, S. Asfaha, Hiroto Kinoshita +17 more
2018Gastroenterology42 citations Open access
Semantic Scholar
Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice
H. Nienhüser, Woosook Kim, E. Malagola, Tuo Ruan +6 more
2020Gut41 citations Open access
Semantic Scholar
Mature gastric chief cells are not required for the development of metaplasia.
Hiroto Kinoshita, Y. Hayakawa, Zheng-Chuan Niu, Mitsuru Konishi +9 more
2018American Journal of Physiology - Gastrointestinal and Liver Physiology39 citations Open access
Semantic Scholar
Role of Muscarinic Acetylcholine Signaling in Gastrointestinal Cancers
Mitsuru Konishi, Y. Hayakawa, K. Koike
2019Biomedicines33 citations Open access
Semantic Scholar
Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium
Hiroto Kinoshita, Y. Hayakawa, Mitsuru Konishi, M. Hata +10 more
2018Journal of Pathology33 citations
Semantic Scholar
Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis
Shigeyuki Kurosaki, Hayato Nakagawa, Hayata Yuki, S. Kawamura +13 more
2021JHEP Reports32 citations Open access
Semantic Scholar
Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation
Weiwei Sheng, E. Malagola, H. Nienhüser, Zheng-Yu Zhang +8 more
2020Cellular and Molecular Gastroenterology and Hepatology32 citations Open access
Semantic Scholar
Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target
J. Arai, Y. Hayakawa, Hiroaki Tateno, K. Murakami +32 more
2024Gastroenterology31 citations Open access
Semantic Scholar
Efficacy and safety of a new rifabutin‐based triple therapy with vonoprazan for refractory Helicobacter pylori infection: A prospective single‐arm study
Y. Hirata, Atsuo Yamada, R. Niikura, S. Shichijo +2 more
2020Helicobacter29 citations
Semantic Scholar
Effect of aspirin use on gastric cancer incidence and survival: A systematic review and meta‐analysis
R. Niikura, Y. Hirata, Y. Hayakawa, Takuya Kawahara +2 more
2019JGH Open29 citations Open access
Semantic Scholar
Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation
H. Fujiwara, K. Tateishi, Kento Misumi, Akimasa Hayashi +17 more
2019Scientific Reports28 citations Open access
Semantic Scholar
Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease
S. Ihara, Y. Hirata, Yohko Hikiba, Aya Yamashita +11 more
2018Journal of Crohn's & Colitis28 citations Open access
Semantic Scholar
Efficacy of Vonoprazan for Gastroesophageal Reflux Symptoms in Patients with Proton Pump Inhibitor-resistant Non-erosive Reflux Disease
R. Niikura, Atsuo Yamada, Y. Hirata, Y. Hayakawa +5 more
2018Internal medicine27 citations Open access
Semantic Scholar
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
Zheng-Yu Jiang, Fei-Jin Wu, P. Laise, Takayuki Tanaka +24 more
2023Cell Stem Cell26 citations
Semantic Scholar
Non-Helicobacter pylori Gastric Microbiome Modulates Prooncogenic Responses and Is Associated With Gastric Cancer Risk
R. Niikura, Y. Hayakawa, N. Nagata, Tohru Miyoshi-Akiayama +21 more
2023Gastro Hep Advances26 citations Open access
Semantic Scholar
Axin2+ peribiliary glands in the periampullary region generate biliary epithelial stem cells that give rise to ampullary carcinoma.
Hayata Yuki, Hayato Nakagawa, Shigeyuki Kurosaki, S. Kawamura +15 more
2021Gastroenterology26 citations Open access
Semantic Scholar
Sessile serrated adenoma detection rate is correlated with adenoma detection rate
D. Ohki, Y. Tsuji, T. Shinozaki, Yoshiki Sakaguchi +14 more
2018World Journal of Gastrointestinal Oncology26 citations Open access
Semantic Scholar
The Tuft Cell-ILC2 Circuit Integrates Intestinal Defense and Homeostasis.
Y. Hayakawa, Timothy C. Wang
2018Cell26 citations Open access
Semantic Scholar
Gastric Stem Cell and Cellular Origin of Cancer
M. Hata, Y. Hayakawa, K. Koike
2018Biomedicines23 citations Open access
Semantic Scholar
Clinicopathological Features of Gastric Cancer with Autoimmune Gastritis
J. Arai, R. Niikura, Y. Hayakawa, Nobumi Suzuki +3 more
2022Biomedicines21 citations Open access
Semantic Scholar
MNX1-HNF1B axis is indispensable for intraductal papillary mucinous neoplasm lineages.
Hiroyuki Kato, K. Tateishi, H. Fujiwara, Takuma Nakatsuka +36 more
2021Gastroenterology17 citations Open access
Semantic Scholar
The Reduction in Gastric Atrophy after Helicobacter pylori Eradication Is Reduced by Treatment with Inhibitors of Gastric Acid Secretion
R. Niikura, Y. Hayakawa, Y. Hirata, K. Ogura +6 more
2019International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Distinct Features of Autoimmune Gastritis in Patients with Open-Type Chronic Gastritis in Japan
Mayo Tsuboi, R. Niikura, Y. Hayakawa, Y. Hirata +2 more
2020Biomedicines16 citations Open access
Semantic Scholar
Use of Antibiotics and Probiotics Reduces the Risk of Metachronous Gastric Cancer after Endoscopic Resection
J. Arai, R. Niikura, Y. Hayakawa, Takuya Kawahara +13 more
2021Biology15 citations Open access
Semantic Scholar
Chemoprevention of Oesophageal Squamous-Cell Carcinoma and Adenocarcinoma: A Multicentre Retrospective Cohort Study
J. Arai, R. Niikura, Y. Hayakawa, Takuya Kawahara +13 more
2021Digestion14 citations Open access
Semantic Scholar
Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway
Kazuki Nakai, Hancheng Lin, S. Yamano, Shinya Tanaka +20 more
2023Nature Communications13 citations Open access
Semantic Scholar
Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis
Hiroyuki Kato, K. Tateishi, H. Fujiwara, Hideaki Ijichi +13 more
2020Cancer Genomics & Proteomics12 citations Open access
Semantic Scholar
Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer
R. Niikura, Y. Hayakawa, Y. Hirata, Mitsuru Konishi +7 more
2018Cancer Prevention Research12 citations Open access
Semantic Scholar
Comparison of clinical utility of deep learning‐based systems for small‐bowel capsule endoscopy reading
Tomonori Aoki, Atsuo Yamada, S. Oka, Mayo Tsuboi +21 more
2023Journal of Gastroenterology and Hepatology11 citations
Semantic Scholar
OLGIM staging and proton pump inhibitor use predict the risk of gastric cancer
J. Arai, R. Niikura, Y. Hayakawa, Tomonori Aoki +3 more
2021Gut10 citations
Semantic Scholar

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K. Koike×26
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Atsuo Yamada×14

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M. Hata — researcher profile on SciRah

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