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Michael J. Wagenbach · SciRah

Researcher profile · Semantic Scholar

Michael J. Wagenbach

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Michael J. Wagenbach — researcher profile on SciRah

h-index: 26
Works: 51
Citations: 5,422

Most-cited papers

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
A. J. Brake, Michael J. Wagenbach, D. Julius
1994Nature949 citations
Semantic Scholar
Aurora B regulates MCAK at the mitotic centromere.
P. D. Andrews, Yulia Ovechkina, N. Morrice, Michael J. Wagenbach +3 more
2004Developmental Cell598 citations Open access
Semantic Scholar
Kinesin Takes One 8-nm Step for Each ATP That It Hydrolyzes*
David L. Coy, Michael J. Wagenbach, J. Howard
1999Journal of Biological Chemistry363 citations Open access
Semantic Scholar
Motor-dependent microtubule disassembly driven by tubulin tyrosination
Leticia Peris, Michael J. Wagenbach, L. Lafanechère, J. Brocard +5 more
2009Journal of Cell Biology352 citations Open access
Semantic Scholar
The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment.
Jason K. Stumpff, G. von Dassow, Michael J. Wagenbach, Charles L. Asbury +1 more
2008Developmental Cell350 citations Open access
Semantic Scholar
Kinesin’s tail domain is an inhibitory regulator of the motor domain
David L. Coy, W. Hancock, Michael J. Wagenbach, J. Howard
1999Nature Cell Biology338 citations
Semantic Scholar
Mitotic Centromere–associated Kinesin Is Important for Anaphase Chromosome Segregation
Ted Maney, A. Hunter, Michael J. Wagenbach, L. Wordeman
1998Journal of Cell Biology320 citations Open access
Semantic Scholar
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.
Amity L. Manning, Neil J. Ganem, S. Bakhoum, Michael J. Wagenbach +2 more
2007Molecular Biology of the Cell253 citations Open access
Semantic Scholar
Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension
Jason K. Stumpff, Michael J. Wagenbach, Andrew D. Franck, Charles L. Asbury +1 more
2012Developmental Cell180 citations Open access
Semantic Scholar
Molecular Dissection of the Microtubule Depolymerizing Activity of Mitotic Centromere-associated Kinesin*
Ted Maney, Michael J. Wagenbach, L. Wordeman
2001Journal of Biological Chemistry164 citations Open access
Semantic Scholar
MCAK associates with the tips of polymerizing microtubules
A. Moore, Kathleen E. Rankin, G. von Dassow, Leticia Peris +5 more
2005Journal of Cell Biology161 citations Open access
Semantic Scholar
MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover
L. Wordeman, Michael J. Wagenbach, G. von Dassow
2007Journal of Cell Biology155 citations Open access
Semantic Scholar
In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends.
Susana Montenegro Gouveia, K. Leslie, L. Kapitein, R. Buey +8 more
2010Current Biology141 citations Open access
Semantic Scholar
De novo design of self-assembling helical protein filaments
Hao Shen, J. Fallas, E. Lynch, W. Sheffler +15 more
2018Science139 citations Open access
Semantic Scholar
A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A
Jason K. Stumpff, Ya-Qing Du, Chauca A. English, Z. Maliga +4 more
2011Molecules and Cells137 citations Open access
Semantic Scholar
Synthesis of Wild Type and Mutant Human Hemoglobins in Saccharomyces cerevisiae
Michael J. Wagenbach, K. O'Rourke, L. Vitez, A. Wieczorek +4 more
1991Bio/Technology110 citations
Semantic Scholar
K-loop insertion restores microtubule depolymerizing activity of a “neckless” MCAK mutant
Yulia Ovechkina, Michael J. Wagenbach, L. Wordeman
2002Journal of Cell Biology108 citations Open access
Semantic Scholar
Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK
Jeremy R. Cooper, Michael J. Wagenbach, Charles L. Asbury, L. Wordeman
2009Nature Structural &Molecular Biology90 citations Open access
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MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment
Sarah B. Domnitz, Michael J. Wagenbach, Justin Decarreau, L. Wordeman
2012Journal of Cell Biology76 citations Open access
Semantic Scholar
MCAK, a Kin I kinesin, increases the catastrophe frequency of steady‐state HeLa cell microtubules in an ATP‐dependent manner in vitro
Cori N. Newton, Michael J. Wagenbach, Yulia Ovechkina, L. Wordeman +1 more
2004FEBS Letters52 citations
Semantic Scholar
The Role of the Kinesin-13 Neck in Microtubule Depolymerization
C. Moores, Jeremy R. Cooper, Michael J. Wagenbach, Yulia Ovechkina +2 more
2006Cell Cycle45 citations Open access
Semantic Scholar
A new model for binding of kinesin 13 to curved microtubule protofilaments
Anke M. Mulder, Alex Glavis-Bloom, C. Moores, Michael J. Wagenbach +3 more
2009Journal of Cell Biology44 citations Open access
Semantic Scholar
MUTATIONS IN THE ATP‐BINDING DOMAIN AFFECT THE SUBCELLULAR DISTRIBUTION OF MITOTIC CENTROMERE‐ASSOCIATED KINESIN (MCAK)
L. Wordeman, Michael J. Wagenbach, Todd Maney
1999Cell Biology International43 citations
Semantic Scholar
A tetrameric kinesin, Kif25, suppresses centrosome separation to establish proper spindle orientation
Justin Decarreau, Michael J. Wagenbach, E. Lynch, Aaron R. Halpern +3 more
2017Nature Cell Biology33 citations Open access
Semantic Scholar
A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
Michael J. Wagenbach, Sarah B. Domnitz, L. Wordeman, Jeremy R. Cooper
2008Journal of Cell Biology30 citations Open access
Semantic Scholar
A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis
Eric A. Horne, P. Diaz, P. Cimino, E. Jung +10 more
2020Neuro-Oncology Advances28 citations Open access
Semantic Scholar
Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins
L. Wordeman, Justin Decarreau, J. Vicente, Michael J. Wagenbach
2016Molecular Biology of the Cell26 citations Open access
Semantic Scholar
Secondary structure and compliance of a predicted flexible domain in kinesin-1 necessary for cooperation of motors.
Á. Crevenna, Sineej Madathil, Daniel N Cohen, Michael J. Wagenbach +2 more
2008Biophysical Journal24 citations Open access
Semantic Scholar
Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells
P. Diaz, Eric A. Horne, Cong Xu, E. Hamel +8 more
2018European journal of medicinal chemistry23 citations Open access
Semantic Scholar
ST-11: a new brain-penetrant microtubule-destabilizing agent with therapeutic potential for glioblastoma multiforme
A. Cherry, Brian R. Haas, Alipi V Naydenov, Susan Fung +14 more
2016Molecular Cancer Therapeutics22 citations Open access
Semantic Scholar
Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization
Kyle M. Burns, Michael J. Wagenbach, L. Wordeman, D. Schriemer
2014Structure16 citations Open access
Semantic Scholar
Functional characterization of MCAK/Kif2C cancer mutations using high-throughput microscopic analysis
Michael J. Wagenbach, J. Vicente, Yulia Ovechkina, Sarah B. Domnitz +1 more
2019Molecular Biology of the Cell14 citations Open access
Semantic Scholar
HX‐MS2 for high performance conformational analysis of complex protein states
Kyle M. Burns, V. Sarpe, Michael J. Wagenbach, L. Wordeman +1 more
2015Protein Science9 citations Open access
Semantic Scholar
Non-enzymatic activity of the α-tubulin acetyltransferase αTAT1 limits synaptic bouton growth in neurons
Courtney Coombes, Harriet A. J. Saunders, A. G. Mannava, Dena M. Johnson-Schlitz +10 more
2020Current Biology8 citations Open access
Semantic Scholar
In vitro and in vivo analysis of microtubule-destabilizing kinesins.
Jason K. Stumpff, Jeremy R. Cooper, Sarah B. Domnitz, A. Moore +3 more
2007Methods in molecular biology8 citations Open access
Semantic Scholar
Direct Functional Interaction of the Kinesin-13 Family Membrane Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1)*♦
Ruibai Luo, Pei-Wen Chen, Michael J. Wagenbach, X. Jian +3 more
2016Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1).
Ruibai Luo, Pei-Wen Chen, Michael J. Wagenbach, X. Jian +3 more
2016Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Production of CRISPR-Cas9 transgenic cell lines for knocksideways studies
Michael J. Wagenbach, J. Vicente, Wren Wagenbach, Linda Wordeman
2023Current Protocols4 citations Open access
Semantic Scholar
The kinesin motor Kif9 regulates centriolar satellite positioning during interphase
J. Vicente, Michael J. Wagenbach, Justin Decarreau, A. Zelter +3 more
2025Current Biology2 citations Open access
Semantic Scholar
The Kinesin Motor Kif9 Disrupts Primary Cilia Length by Mispositioning Centriolar Satellites
J. Vicente, Jacob R. Weiss, Michael J. Wagenbach, Linda Wordeman
2025The FASEB Journal1 citations Open access
Semantic Scholar
Using antisense technology to study mitosis.
Linda Wordeman, Michael J. Wagenbach
1999Methods in Cell Biology1 citations
Semantic Scholar
MCAK/Kif2C centromeric activity level tunes K-fiber stability
Michael J. Wagenbach, J. Vicente, Linda Wordeman
2025bioRxiv0 citations Open access
Semantic Scholar
The kinesin motor Kif9 regulates centriolar satellite positioning and mitotic progression
J. Vicente, Michael J. Wagenbach, Justin Decarreau, A. Zelter +3 more
2024bioRxiv0 citations Open access
Semantic Scholar
EXTH-53. A BRAIN-PENETRANT MICROTUBULE-TARGETING AGENT THAT DISRUPTS HALLMARKS OF GLIOMA TUMORIGENESIS
Eric A. Horne, Juan J. Vicente Ruiz, P. Cimino, E. Jung +9 more
20200 citations Open access
Semantic Scholar
DDIS-29. BRAIN-PENETRANT MICROTUBULE-TARGETING AGENT, ST-401, KILLS GLIOBLASTOMA THROUGH A NOVEL MECHANISM
Eric A. Horne, Cong Xu, J. Vicente, P. Cimino +9 more
2019Neuro-Oncology0 citations Open access
Semantic Scholar
Erratum
V. Sarpe, Michael J. Wagenbach, L. Wordeman, D. Schriemer
2016Protein Science0 citations Open access
Semantic Scholar
ATPS-06BRAIN-PENETRANT ALKYLINDOLE COMPOUNDS PROMOTE APOPTOSIS IN GLIOMA CELLS THROUGH MICROTUBULE DESTABILIZATION
A. Cherry, Brian R. Haas, Alipi V Naydenov, Susan Fung +13 more
20150 citations Open access
Semantic Scholar
Procedure for preparation of hemoglobin and hemoglobin derivatives from handling of bacteria and leaves.
S. Hoffmann, D. Looker, M. Rosendal, G. Stetler +1 more
19900 citations
Semantic Scholar
Preparation of hemoglobin and analogues thereof by bacteria or yeasts
Stephen J. Hoffman, D. Looker, M. Rosendal, G. Stetler +2 more
19900 citations
Semantic Scholar
Preparation of yeast and bacteria of hemoglobin and analogues thereof
Stephen J. Hoffman, D. Looker, M. Rosendal, G. Stetler +2 more
19900 citations
Semantic Scholar

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L. Wordeman×36
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J. Vicente×10
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Yulia Ovechkina×6
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Eric A. Horne — researcher profile on SciRah

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Jason K. Stumpff×4

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Jason K. Stumpff — researcher profile on SciRah

Charles L. Asbury×4

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Jeremy R. Cooper — researcher profile on SciRah