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A. P. VanDemark · SciRah

Researcher profile · Semantic Scholar

A. P. VanDemark

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A. P. VanDemark — researcher profile on SciRah

h-index: 28
Works: 82
Citations: 3,858

Most-cited papers

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals
S. Wenzel, Y. Tyurina, Jin-Ming Zhao, C. Croix +23 more
2017Cell882 citations Open access
Semantic Scholar
Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing
Mark R. Macbeth, H. Schubert, A. P. VanDemark, A. Lingam +2 more
2005Science450 citations Open access
Semantic Scholar
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.
A. P. VanDemark, R. M. Hofmann, C. Tsui, C. Pickart +1 more
2001Cell313 citations Open access
Semantic Scholar
Potent D-peptide inhibitors of HIV-1 entry
Brett D. Welch, A. P. VanDemark, A. Héroux, C. Hill +1 more
2007Proceedings of the National Academy of Sciences of the United States of America240 citations Open access
Semantic Scholar
The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition.
A. P. VanDemark, Mary Blanksma, E. Ferris, A. Héroux +2 more
2006Molecules and Cells149 citations Open access
Semantic Scholar
Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
A. P. VanDemark, M. Kasten, E. Ferris, A. Héroux +2 more
2007Molecules and Cells138 citations Open access
Semantic Scholar
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
K. G. Hicks, Ahmad A. Cluntun, H. Schubert, Sean R. Hackett +42 more
2023Science137 citations Open access
Semantic Scholar
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
T. Anthonymuthu, Y. Tyurina, Wan-Yang Sun, K. Mikulska-Ruminska +12 more
2020Redox Biology122 citations Open access
Semantic Scholar
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells
Jin-Ming Zhao, H. Dar, Yanhan Deng, C. S. St Croix +14 more
2020Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin
A. Wier, M. Mayekar, A. Héroux, K. Arndt +1 more
2013Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation Through an Interaction with Rad6
S. Branden Van Oss, M. Shirra, Alain R. Bataille, A. Wier +10 more
2016Molecules and Cells103 citations Open access
Semantic Scholar
Structural and Functional Analysis of the Spt16p N-terminal Domain Reveals Overlapping Roles of yFACT Subunits*
A. P. VanDemark, H. Xin, L. McCullough, R. Rawlins +5 more
2008Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE
T. Anthonymuthu, Elizabeth M. Kenny, I. Shrivastava, Y. Tyurina +17 more
2018Journal of the American Chemical Society79 citations Open access
Semantic Scholar
Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52
W. Gaines, Stephen K Godin, Faiz F. Kabbinavar, T. Rao +3 more
2015Nature Communications76 citations Open access
Semantic Scholar
Structural basis of ubiquitylation.
A. P. VanDemark, C. Hill
2002Current Opinion in Structural Biology68 citations
Semantic Scholar
The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination
Stephen K Godin, A. Wier, Faiz F. Kabbinavar, Dominique S Bratton-Palmer +4 more
2013Nucleic Acids Research66 citations Open access
Semantic Scholar
A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease
Alicia M. Celotto, Zhao-Hui Liu, A. P. VanDemark, M. Palladino
2012Brain and Behavior54 citations Open access
Semantic Scholar
Cdc73 Subunit of Paf1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf1 Complex with Chromatin*
C. G. Amrich, Christopher P. Davis, W. Rogal, M. Shirra +4 more
2012Journal of Biological Chemistry52 citations Open access
Semantic Scholar
The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice
Debamitra Das, Jenna K. Zalewski, S. Mohan, Timothy F. Plageman +2 more
2014Biology Open47 citations Open access
Semantic Scholar
Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1
Carole Jabet, E. Sprague, A. P. VanDemark, C. Wolberger
2000Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity
Bartholomew P. Roland, Kimberly A Stuchul, S. B. Larsen, C. G. Amrich +3 more
2013Journal of Cell Science43 citations Open access
Semantic Scholar
Opening doors into the proteasome
C. Pickart, A. P. VanDemark
2000Nature Structural Biology43 citations
Semantic Scholar
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death
Andrew M. Lamade, Limin Wu, H. Dar, H. Mentrup +24 more
2022Redox Biology42 citations Open access
Semantic Scholar
Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction
S. Mohan, Ryan Rizaldy, Debamitra Das, R. Bauer +4 more
2012Molecular Biology of the Cell41 citations Open access
Semantic Scholar
Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members
K. Mikulska-Ruminska, I. Shrivastava, James M. Krieger, She Zhang +6 more
2019Journal of Chemical Information and Modeling36 citations Open access
Semantic Scholar
Triosephosphate Isomerase I170V Alters Catalytic Site, Enhances Stability and Induces Pathology in a Drosophila Model of TPI Deficiency
Bartholomew P. Roland, C. G. Amrich, Charles J Kammerer, Kimberly A Stuchul +7 more
2014Biochimica et Biophysica Acta36 citations Open access
Semantic Scholar
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway
Joel C. Rosenbaum, Braulio Bonilla, S. R. Hengel, Tony M. Mertz +16 more
2019Nature Communications35 citations Open access
Semantic Scholar
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators
H. Dar, K. Mikulska-Ruminska, Y. Tyurina, D. Luci +24 more
2023Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics
Bartholomew P. Roland, A. Zeccola, S. B. Larsen, C. G. Amrich +6 more
2016PLoS Genetics29 citations Open access
Semantic Scholar
Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology
S. Mohan, Debamitra Das, R. Bauer, A. Héroux +6 more
2013PLoS ONE25 citations Open access
Semantic Scholar
Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily
M. R. Googins, Aigbirhemwen O. Woghiren-Afegbua, Mike Calderon, C. S. St Croix +2 more
2020The FASEB Journal22 citations Open access
Semantic Scholar
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo
Bartholomew P. Roland, K. R. Richards, Stacy L. Hrizo, S. Eicher +10 more
2019Biochimica et Biophysica Acta - Molecular Basis of Disease21 citations Open access
Semantic Scholar
The Structure of Xis reveals the basis for Filament Formation and insight into DNA bending within a mycobacteriophage Intasome
Shweta Singh, Joseph G. Plaks, Nicholas J. Homa, C. G. Amrich +3 more
2013Journal of Molecular Biology21 citations Open access
Semantic Scholar
Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity*
Jenna K. Zalewski, Joshua H. Mo, S. Heber, A. Héroux +3 more
2016Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Cross-talk between diverse serine integrases
Shweta Singh, Kate Rockenbach, R. Dedrick, A. P. VanDemark +1 more
2013Journal of Molecular Biology13 citations Open access
Semantic Scholar
On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w
S. V. Van Oss, S. Parikh, N. Coelho, Aaron Wacholder +13 more
2022bioRxiv12 citations Open access
Semantic Scholar
Protein-Metabolite Interactomics Reveals Novel Regulation of Carbohydrate Metabolism
K. G. Hicks, Ahmad A. Cluntun, H. Schubert, Sean R. Hackett +34 more
2021bioRxiv11 citations Open access
Semantic Scholar
Two-stepping with E1
A. P. VanDemark, C. Hill
2003Nature Structural Biology10 citations
Semantic Scholar
Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency
A. P. VanDemark, Stacy L. Hrizo, S. Eicher, Jules Kowalski +5 more
2022Disease Models & Mechanisms9 citations Open access
Semantic Scholar
Dissection of Structure and Function of the N-Terminal Domain of Mouse DNMT1 Using Regional Frame-Shift Mutagenesis
L. D’Aiuto, Marco Marzulli, K. N. Mohan, E. Borowczyk +3 more
2010PLoS ONE5 citations Open access
Semantic Scholar
E1 on the move.
A. P. VanDemark, C. Hill
2005Molecules and Cells5 citations Open access
Semantic Scholar
SUMO wrestling with specificity.
A. P. VanDemark, C. Hill
2002Structure5 citations Open access
Semantic Scholar
Unexpected growth of a classic yeast auxotroph
S. V. Van Oss, S. Parikh, N. Coelho, Aaron Wacholder +10 more
20223 citations Open access
Semantic Scholar
Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins.
Jenna K. Zalewski, S. Heber, Joshua H. Mo, K. O'Conor +2 more
2017Journal of Visualized Experiments3 citations Open access
Semantic Scholar
Cdc 73 Subunit of Paf 1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf 1 Complex with Chromatin *
C. G. Amrich, Christopher P. Davis, W. Rogal, M. Shirra +4 more
20123 citations
Semantic Scholar
The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition (DOI: 10.1016/j.molcel.2006.03.025)
A. P. VanDemark, Mary Blanksma, E. Ferris, A. Héroux +2 more
20073 citations Open access
Semantic Scholar
Grabbing E2 by the tail
A. P. VanDemark, C. Hill
2004Nature Structural &Molecular Biology3 citations
Semantic Scholar
Biophysical and biochemical studies support PHD inhibitor development as a TPI deficiency therapy
Presley Roberts, Joseph R. Figura, Kaitlin McClure, Grace Coleman +7 more
2026Journal of Cell Science2 citations Open access
Semantic Scholar
Two-stepping with E 1
A. P. VanDemark, C. Hill
20032 citations
Semantic Scholar
The cytotoxic mycobacteriophage protein Phaedrus gp82 interacts with and modulates the activity of the host ATPase, MoxR
Saeed Binsabaan, K. Freeman, G. Hatfull, A. P. VanDemark
2023Journal of Molecular Biology1 citations Open access
Semantic Scholar

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