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I. Bahar · SciRah

Researcher profile · Semantic Scholar

I. Bahar

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I. Bahar — researcher profile on SciRah

h-index: 81
Works: 437
Citations: 30K

Most-cited papers

Redox Lipid Reprogramming Commands Susceptibility of Macrophages and Microglia to Ferroptotic Death.
A. Kapralov, Qin Yang, H. Dar, Y. Tyurina +22 more
2020Nature Chemical Biology616 citations Open access
Semantic Scholar
Mapping Transcriptomic Vector Fields of Single Cells
Xiao-Jie Qiu, Yan Zhang, Jorge D. Martin-Rufino, Chen Weng +18 more
2022Cell434 citations Open access
Semantic Scholar
Allostery in Its Many Disguises: From Theory to Applications
S. Wodak, E. Paci, N. Dokholyan, I. Berezovsky +35 more
2019Structure345 citations Open access
Semantic Scholar
Phospholipase iPLA2β Averts Ferroptosis By Eliminating A Redox Lipid Death Signal
Wan-Yang Sun, V. Tyurin, K. Mikulska-Ruminska, I. Shrivastava +25 more
2021Nature Chemical Biology313 citations Open access
Semantic Scholar
Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation
M. H. Cheng, She Zhang, Rebecca A. Porritt, Magali Noval Rivas +5 more
2020Proceedings of the National Academy of Sciences of the United States of America297 citations Open access
Semantic Scholar
ProDy 2.0: increased scale and scope after 10 years of protein dynamics modelling with Python
She Zhang, James M. Krieger, Yan Zhang, Cihan Kaya +5 more
2021Bioinform.208 citations Open access
Semantic Scholar
HLA class I-associated expansion of TRBV11-2 T cells in Multisystem Inflammatory Syndrome in Children.
Rebecca A. Porritt, L. Paschold, Magali Noval Rivas, M. H. Cheng +12 more
2021Journal of Clinical Investigation154 citations Open access
Semantic Scholar
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis
T. Anthonymuthu, Y. Tyurina, Wan-Yang Sun, K. Mikulska-Ruminska +12 more
2020Redox Biology122 citations Open access
Semantic Scholar
Pharmacological suppression of B7-H4 glycosylation restores antitumor immunity in immune-cold breast cancers
Xin-Xin Song, Zhuan Zhou, Hong-Chun Li, Yifan Xue +6 more
2020Cancer Discovery121 citations Open access
Semantic Scholar
Intrinsic dynamics is evolutionarily optimized to enable allosteric behavior
Yan Zhang, P. Doruker, B. Kaynak, She Zhang +3 more
2019Current Opinion in Structural Biology107 citations Open access
Semantic Scholar
PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells
Jin-Ming Zhao, H. Dar, Yanhan Deng, C. S. St Croix +14 more
2020Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
Monoamine transporters: structure, intrinsic dynamics and allosteric regulation
M. H. Cheng, I. Bahar
2019Nature Structural & Molecular Biology101 citations Open access
Semantic Scholar
Rhapsody: predicting the pathogenicity of human missense variants
Luca Ponzoni, Daniel A. Peñaherrera, Z. Oltvai, I. Bahar
2020Bioinform.98 citations Open access
Semantic Scholar
Structural dynamics is a determinant of the functional significance of missense variants
Luca Ponzoni, I. Bahar
2018Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
COVID-19–associated multisystem inflammatory syndrome in children (MIS-C): A novel disease that mimics toxic shock syndrome—the superantigen hypothesis
Magali Noval Rivas, Rebecca A. Porritt, M. H. Cheng, I. Bahar +1 more
2020Journal of Allergy and Clinical Immunology96 citations Open access
Semantic Scholar
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation
A. White, Karina A. Peña, L. Clark, Christian Santa Maria +15 more
2021Science Signaling80 citations Open access
Semantic Scholar
Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment
M. H. Cheng, James M. Krieger, B. Kaynak, M. Arditi +1 more
2021bioRxiv77 citations Open access
Semantic Scholar
Multisystem Inflammatory Syndrome in Children in the United States.
M. Arditi, I. Bahar
2020New England Journal of Medicine58 citations Open access
Semantic Scholar
A novel strategy to block mitotic progression for targeted therapy
Junlong Chi, Hong-Chun Li, Zhuan Zhou, Javier Izquierdo-Ferrer +8 more
2019EBioMedicine57 citations Open access
Semantic Scholar
Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy.
C. O. Sorzano, A. Jiménez, J. Mota, J. Vilas +18 more
2019Acta Crystallographica Section F Structural Biology Communications57 citations Open access
Semantic Scholar
Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation
J. Dagvadorj, K. Mikulska-Ruminska, G. Tumurkhuu, R. Ratsimandresy +14 more
2020Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations
M. H. Cheng, She Zhang, Rebecca A. Porritt, M. Arditi +1 more
2020bioRxiv54 citations Open access
Semantic Scholar
Essential site scanning analysis: A new approach for detecting sites that modulate the dispersion of protein global motions
B. Kaynak, I. Bahar, P. Doruker
2020Computational and Structural Biotechnology Journal52 citations Open access
Semantic Scholar
Llamanade: an open-source computational pipeline for robust nanobody humanization
Z. Sang, Yufei Xiang, I. Bahar, Yi Shi
2021bioRxiv50 citations Open access
Semantic Scholar
Shared Signature Dynamics Tempered by Local Fluctuations Enables Fold Adaptability and Specificity
She Zhang, Hong-Chun Li, James M. Krieger, I. Bahar
2019Molecular biology and evolution50 citations Open access
Semantic Scholar
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
L. Clark, James M. Krieger, A. White, V. Bondarenko +13 more
2020Nature Chemical Biology47 citations Open access
Semantic Scholar
Anti-Ferroptosis Drug Enhances Total-Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis
S. Thermozier, W. Hou, Xi-chen Zhang, D. Shields +11 more
2020Radiation Research45 citations Open access
Semantic Scholar
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death
Andrew M. Lamade, Limin Wu, H. Dar, H. Mentrup +24 more
2022Redox Biology42 citations Open access
Semantic Scholar
NO● Represses the Oxygenation of Arachidonoyl PE by 15LOX/PEBP1: Mechanism and Role in Ferroptosis
K. Mikulska-Ruminska, T. Anthonymuthu, Anastasia Levkina, I. Shrivastava +4 more
2021International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Impact of new variants on SARS-CoV-2 infectivity and neutralization: A molecular assessment of the alterations in the spike-host protein interactions
M. H. Cheng, James M. Krieger, A. Banerjee, Yufei Xiang +4 more
2022iScience37 citations Open access
Semantic Scholar
EIF3H orchestrates Hippo pathway-mediated oncogenesis via catalytic control of YAP stability
Zhuan Zhou, Honghong Zhou, Luca Ponzoni, Ai-Ping Luo +7 more
2020Cancer Research36 citations Open access
Semantic Scholar
Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members
K. Mikulska-Ruminska, I. Shrivastava, James M. Krieger, She Zhang +6 more
2019Journal of Chemical Information and Modeling36 citations Open access
Semantic Scholar
A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy
Zhuan Zhou, Zhiwei Feng, Dong Hu, Peng Yang +6 more
2019EBioMedicine36 citations Open access
Semantic Scholar
A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
M. H. Cheng, Rebecca A. Porritt, M. N. Rivas, James M. Krieger +6 more
2020bioRxiv35 citations Open access
Semantic Scholar
Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related Disorders
Yonjung Kim, I. Jun, Dong-Hoon Shin, Jihoon G. Yoon +7 more
2019Cellular and Molecular Gastroenterology and Hepatology35 citations Open access
Semantic Scholar
Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis
A. Amoscato, T. Anthonymuthu, O. Kapralov, L. J. Sparvero +9 more
2023Redox Biology31 citations Open access
Semantic Scholar
Towards gaining sight of multiscale events: utilizing network models and normal modes in hybrid methods
James M. Krieger, P. Doruker, A. Scott, D. Perahia +1 more
2020Current Opinion in Structural Biology31 citations Open access
Semantic Scholar
A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster
Andrea N. Belovich, J. Aguilar, Samuel J. Mabry, M. H. Cheng +8 more
2019Molecular Psychiatry31 citations Open access
Semantic Scholar
Pharmmaker: Pharmacophore modeling and hit identification based on druggability simulations
Ji-Young Lee, James M. Krieger, Hong-Chun Li, I. Bahar
2019Protein Science31 citations Open access
Semantic Scholar
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators
H. Dar, K. Mikulska-Ruminska, Y. Tyurina, D. Luci +24 more
2023Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Implications.
Jean-Pierre Vilardaga, L. Clark, A. White, Ieva Sutkeviciute +2 more
2022Endocrine reviews29 citations Open access
Semantic Scholar
ClustENMD: efficient sampling of biomolecular conformational space at atomic resolution
B. Kaynak, She Zhang, I. Bahar, P. Doruker
2021bioRxiv29 citations Open access
Semantic Scholar
Sampling of Protein Conformational Space Using Hybrid Simulations: A Critical Assessment of Recent Methods
B. Kaynak, James M. Krieger, B. Dudas, Zakaria L. Dahmani +6 more
2022Frontiers in Molecular Biosciences28 citations Open access
Semantic Scholar
Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
Qingya Shi, Fen Pei, G. Silverman, Stephen C. Pak +3 more
2020bioRxiv28 citations Open access
Semantic Scholar
Precise druggability of the PTH type 1 receptor
Ieva Sutkeviciute, Ji-Young Lee, A. White, Christian Santa Maria +13 more
2021Nature Chemical Biology25 citations Open access
Semantic Scholar
Discovery of (R)-N-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity In Vivo
Michał Abram, M. Jakubiec, K. Reeb, M. H. Cheng +18 more
2022Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Approximating deformation fields for the analysis of continuous heterogeneity of biological macromolecules by 3D Zernike polynomials
D. Herreros, R. Lederman, James M. Krieger, A. Jiménez-Moreno +7 more
2021IUCrJ24 citations Open access
Semantic Scholar
An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z
Yan Wang, M. C. Çobanoğlu, Jie Li, T. Hidvegi +9 more
2019PLoS ONE24 citations Open access
Semantic Scholar
Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology
D. Taylor, Albert Gough, M. Schurdak, Lawrence A. Vernetti +7 more
2019Handbook of Experimental Pharmacology23 citations Open access
Semantic Scholar
QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics
Hong-Chun Li, Fen Pei, D. L. Taylor, I. Bahar
2020Bioinform.21 citations Open access
Semantic Scholar

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