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A. Arena · SciRah

Researcher profile · Semantic Scholar

A. Arena

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A. Arena — researcher profile on SciRah

h-index: 21
Works: 61
Citations: 1,499

Most-cited papers

Neutrophil-to-Lymphocyte Ratio (NLR) Is a Promising Predictor of Mortality and Admission to Intensive Care Unit of COVID-19 Patients
Matteo Regolo, Mauro Vaccaro, Alessandra Sorce, B. Stancanelli +14 more
2022Journal of Clinical Medicine110 citations Open access
Semantic Scholar
Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm.
E. Barone, F. Di Domenico, T. Cassano, A. Arena +5 more
2016Free Radical Biology & Medicine102 citations
Semantic Scholar
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
A. Tramutola, Chiara Lanzillotta, E. Barone, A. Arena +6 more
2018Translational Neurodegeneration96 citations Open access
Semantic Scholar
Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence
A. Arena, T. Zimmer, J. van Scheppingen, A. Korotkov +14 more
2018Brain Pathology83 citations Open access
Semantic Scholar
Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-A system: insights for transition to Alzheimer Disease
F. Di Domenico, Gilda Pupo, C. Mancuso, E. Barone +7 more
2015Journal of Alzheimer's Disease72 citations Open access
Semantic Scholar
Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo — in search of potential anti-epileptogenic strategies for temporal lobe epilepsy
C. Drion, J. van Scheppingen, A. Arena, Karlijne W Geijtenbeek +4 more
2018Journal of Neuroinflammation70 citations Open access
Semantic Scholar
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome
F. Di Domenico, A. Tramutola, E. Barone, Chiara Lanzillotta +9 more
2019Redox Biology64 citations Open access
Semantic Scholar
New Insights into Curcumin- and Resveratrol-Mediated Anti-Cancer Effects
A. Arena, M. Romeo, Rossella Benedetti, L. Masuelli +3 more
2021Pharmaceuticals63 citations Open access
Semantic Scholar
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease.
Nidhi Sharma, A. Tramutola, Chiara Lanzillotta, A. Arena +6 more
2019Neurobiology of Disease57 citations Open access
Semantic Scholar
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases
Ilaria Genovese, Flavia Giamogante, L. Barazzuol, T. Battista +19 more
2020Cell Death and Disease55 citations Open access
Semantic Scholar
Sialic Acid-Siglec Axis in Human Immune Regulation, Involvement in Autoimmunity and Cancer and Potential Therapeutic Treatments
Elena Gianchecchi, A. Arena, A. Fierabracci
2021International Journal of Molecular Sciences53 citations Open access
Semantic Scholar
Developmental Expression and Dysregulation of miR-146a and miR-155 in Down's Syndrome and Mouse Models of Down's Syndrome and Alzheimer's Disease.
A. Arena, Anand M. Iyer, I. Milenkovic, Gábor G. Kovács +3 more
2017Current Alzheimer Research52 citations
Semantic Scholar
Disturbance of redox homeostasis in Down Syndrome: role of iron dysmetabolism
E. Barone, A. Arena, E. Head, D. Butterfield +1 more
2017Free Radical Biology & Medicine51 citations Open access
Semantic Scholar
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress
Rossella Benedetti, M. Romeo, A. Arena, M. S. Gilardini Montani +3 more
2022Cell Death Discovery47 citations Open access
Semantic Scholar
Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology
A. Tramutola, F. Di Domenico, E. Barone, A. Arena +7 more
2017Antioxidants and Redox Signaling47 citations Open access
Semantic Scholar
Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome
A. Tramutola, Chiara Lanzillotta, A. Arena, E. Barone +2 more
2015Neurodegenerative Diseases44 citations
Semantic Scholar
Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity.
F. A. Cimini, A. Arena, I. Barchetta, A. Tramutola +14 more
2019Biochimica et Biophysica Acta - Molecular Basis of Disease37 citations Open access
Semantic Scholar
ACTIVATION OF p53 IN DOWN SYNDROME AND IN THE Ts65Dn MOUSE BRAIN IS ASSOCIATED WITH A PRO-APOPTOTIC PHENOTYPE
A. Tramutola, Gilda Pupo, F. Di Domenico, E. Barone +7 more
2016Journal of Alzheimer's Disease36 citations Open access
Semantic Scholar
Modulation of GLP-1 signaling as a novel therapeutic approach in the treatment of Alzheimer’s disease pathology
A. Tramutola, A. Arena, C. Cini, D. Butterfield +1 more
2017Expert Review of Neurotherapeutics35 citations
Semantic Scholar
CHRONIC ACTIVATION OF ANTIOXIDANT PATHWAYS AND IRON ACCUMULATION IN EPILEPTOGENIC MALFORMATIONS
T. Zimmer, Giulia Ciriminna, A. Arena, J. Anink +12 more
2019Neuropathology and Applied Neurobiology30 citations Open access
Semantic Scholar
COVID-19: A Review on Diagnosis, Treatment, and Prophylaxis
A. Fierabracci, A. Arena, P. Rossi
2020International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and KSHV replication.
A. Arena, Maria Saveria Gilardini Montani, M. Romeo, Rossella Benedetti +2 more
2021Biochimica et biophysica acta. Molecular cell research20 citations Open access
Semantic Scholar
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor
M. Romeo, M. S. Gilardini Montani, Rossella Benedetti, A. Arena +2 more
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells
A. Arena, M. Romeo, Rossella Benedetti, M. S. Gilardini Montani +1 more
2022Biomedicines18 citations Open access
Semantic Scholar
p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity
A. Arena, A. Stigliano, E. Belcastro, E. Giorda +5 more
2021Frontiers in Immunology17 citations Open access
Semantic Scholar
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression
Rossella Benedetti, M. Romeo, A. Arena, M. S. Gilardini Montani +2 more
2024Autophagy16 citations Open access
Semantic Scholar
Role of UPR Sensor Activation in Cell Death–Survival Decision of Colon Cancer Cells Stressed by DPE Treatment
Rossella Benedetti, M. S. Gilardini Montani, M. Romeo, A. Arena +3 more
2021Biomedicines16 citations Open access
Semantic Scholar
HSPs/STAT3 Interplay Sustains DDR and Promotes Cytokine Release by Primary Effusion Lymphoma Cells
R. Gonnella, A. Arena, Roberta Zarrella, M. S. Gilardini Montani +2 more
2023International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Improvement of Lipoplexes With a Sialic Acid Mimetic to Target the C1858T PTPN22 Variant for Immunotherapy in Endocrine Autoimmunity
A. Arena, E. Belcastro, Francesca Ceccacci, S. Petrini +9 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53
M. Romeo, M. S. Gilardini Montani, Rossella Benedetti, A. Arena +2 more
2021Biomolecules12 citations Open access
Semantic Scholar
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53.
M. Romeo, M. S. Gilardini Montani, Rossella Benedetti, A. Arena +5 more
2021Experimental Cell Research12 citations Open access
Semantic Scholar
NRF2 and STAT3: friends or foes in carcinogenesis?
A. Arena, M. Romeo, Rossella Benedetti, M. S. Gilardini Montani +4 more
2023Discover Oncology11 citations Open access
Semantic Scholar
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
Rossella Benedetti, A. Arena, M. Romeo, M. S. Gilardini Montani +4 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated anti-oxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation.
M. S. Gilardini Montani, G. Tarquini, R. Santarelli, R. Gonnella +5 more
2021Carcinogenesis11 citations
Semantic Scholar
Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1
M. Romeo, M. S. Gilardini Montani, R. Santarelli, Rossella Benedetti +2 more
2023Discover Oncology10 citations Open access
Semantic Scholar
Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients
Marsha Pellegrino, Gianandrea Traversi, A. Arena, M. Cappa +5 more
2020PLoS ONE10 citations Open access
Semantic Scholar
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway
M. Romeo, M. S. Gilardini Montani, A. Arena, Rossella Benedetti +2 more
2022Biomedicines8 citations Open access
Semantic Scholar
EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis
R. Santarelli, Lorenzo Evangelista, Chiara Pompili, Salvatore Lo Presti +6 more
2023Virus Research7 citations Open access
Semantic Scholar
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
A. Arena, M. Romeo, Rossella Benedetti, M. S. Gilardini Montani +1 more
2022Biochemical and Biophysical Research Communications - BBRC7 citations
Semantic Scholar
Preparation and In Vitro Evaluation of RITUXfab-Decorated Lipoplexes to Improve Delivery of siRNA Targeting C1858T PTPN22 Variant in B Lymphocytes
A. Arena, E. Belcastro, A. Accardo, A. Sandomenico +9 more
2021International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
JQ-1/Bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of pro-survival mechanisms.
A. Arena, M. Romeo, Rossella Benedetti, Maria Saveria Gilardini Montani +1 more
2023Experimental Hematology6 citations Open access
Semantic Scholar
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets
R. Gonnella, Roberta Zarrella, Michele Di Crosta, Rossella Benedetti +5 more
2023Cancers6 citations Open access
Semantic Scholar
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells.
M. Romeo, Maria Saveria Gilardini Montani, Rossella Benedetti, A. Arena +2 more
2022Virus Research6 citations Open access
Semantic Scholar
MicroRNA519d and microRNA4758 can identify gangliogliomas from dysembryoplastic neuroepithelial tumours and astrocytomas
A. Bongaarts, A. Prabowo, A. Arena, J. Anink +17 more
2018OncoTarget6 citations Open access
Semantic Scholar
Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism.
L. Di Menna, Rosamaria Orlando, Giovanna D’Errico, R. P. Ginerete +13 more
2023Neuropharmacology4 citations
Semantic Scholar
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice
A. Arena, M. Romeo, A. Pò, Rossella Benedetti +6 more
2023Microbiology spectrum4 citations Open access
Semantic Scholar
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma Cells
Michele Di Crosta, A. Arena, Rossella Benedetti, M. S. Gilardini Montani +1 more
2024Current Issues in Molecular Biology3 citations Open access
Semantic Scholar
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma
A. Arena, M. Romeo, C. Focaccetti, E. Anastasiadou +11 more
2023British Journal of Haematology2 citations Open access
Semantic Scholar
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells
A. Arena, Michele Di Crosta, R. Gonnella, Roberta Zarrella +6 more
2023International Journal of Molecular Sciences2 citations Open access
Semantic Scholar
New insights into the Bortezomib‐induced cytotoxic and resistance mechanisms in a primary effusion lymphoma mouse model
M. Romeo, C. Focaccetti, A. Arena, Rossella Benedetti +8 more
2024Hematological Oncology1 citations Open access
Semantic Scholar

Frequent co-authors

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M. Cirone×25
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M. Cirone — researcher profile on SciRah
Rossella Benedetti×23
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Rossella Benedetti — researcher profile on SciRah
M. S. Gilardini Montani×22
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M. S. Gilardini Montani — researcher profile on SciRah
M. Romeo×21
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M. Romeo — researcher profile on SciRah

×13

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M. Perluigi — researcher profile on SciRah

R. Santarelli×12

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R. Santarelli — researcher profile on SciRah

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E. Barone — researcher profile on SciRah

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G. D'Orazi — researcher profile on SciRah

R. Gonnella×10

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R. Gonnella — researcher profile on SciRah

F. Di Domenico×9

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F. Di Domenico — researcher profile on SciRah

A. Tramutola×9

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A. Tramutola — researcher profile on SciRah

D. Butterfield×9

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D. Butterfield — researcher profile on SciRah