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N. Porter · SciRah

Researcher profile · Semantic Scholar

N. Porter

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N. Porter — researcher profile on SciRah

h-index: 65
Works: 392
Citations: 17K

Most-cited papers

Free radical lipid peroxidation: mechanisms and analysis.
Huiyong Yin, Libin Xu, N. Porter
2011Chemical Reviews1,787 citations
Semantic Scholar
Free Radical Oxidation of Polyunsaturated Lipids: New Mechanistic Insights and the Development of Peroxyl Radical Clocks
D. Pratt, K. Tallman, N. Porter
2011Accounts of Chemical Research321 citations Open access
Semantic Scholar
Global, in situ, site-specific analysis of protein S-sulphenylation
Jing Yang, Vinayak Gupta, K. Tallman, N. Porter +2 more
2015Nature Protocols138 citations Open access
Semantic Scholar
A Perspective on Free Radical Autoxidation: The Physical Organic Chemistry of Polyunsaturated Fatty Acid and Sterol Peroxidation
N. Porter
2013Journal of Organic Chemistry114 citations Open access
Semantic Scholar
Small Amounts of Isotope-reinforced Polyunsaturated Fatty Acids Suppress Lipid Autoxidation
Shauna A. Hill, C. Lamberson, Libin Xu, R. To +9 more
2012Free Radical Biology & Medicine111 citations Open access
Semantic Scholar
An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome[S]
Libin Xu, Ž. Korade, Dale A. Rosado, Wei Liu +2 more
2011Journal of Lipid Research99 citations Open access
Semantic Scholar
Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells
Jing Yang, K. Tallman, N. Porter, D. Liebler
2015Analytical Chemistry85 citations Open access
Semantic Scholar
DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemi-Opitz Syndrome model
Libin Xu, K. Mirnics, A. Bowman, Wei Liu +3 more
2011Neurobiology of Disease84 citations Open access
Semantic Scholar
Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems
Simona G. Codreanu, J. Ullery, Jing Zhu, K. Tallman +5 more
2014Molecular & Cellular Proteomics75 citations Open access
Semantic Scholar
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts
Ž. Korade, Hye-Young H. Kim, K. Tallman, Wei Liu +5 more
2016Journal of Medicinal Chemistry63 citations Open access
Semantic Scholar
Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ
V. Hammond, A. Morgan, S. Lauder, Christopher P. Thomas +13 more
2012Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Ex Vivo Oxidation in Tissue and Plasma Assays of Hydroxyoctadecadienoates: (Z,E/E,E)-Stereoisomer Ratios
Wei Liu, Huiyong Yin, Y. Akazawa, Y. Yoshida +2 more
2010Chemical Research in Toxicology62 citations Open access
Semantic Scholar
Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes*
L. Fu, Ke-Ke Liu, Mingan Sun, Cai-Ping Tian +8 more
2017Molecular & Cellular Proteomics61 citations Open access
Semantic Scholar
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome
Ž. Korade, Libin Xu, K. Mirnics, N. Porter
2012Journal of Inherited Metabolic Disease61 citations Open access
Semantic Scholar
Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]
Libin Xu, Ž. Korade, Dale A. Rosado, K. Mirnics +1 more
2013Journal of Lipid Research60 citations Open access
Semantic Scholar
Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols
Navdar Sever, R. K. Mann, Libin Xu, W. J. Snell +3 more
2016Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI
Libin Xu, Michal Kliman, J. G. Forsythe, Ž. Korade +3 more
2015Journal of the American Society for Mass Spectrometry53 citations Open access
Semantic Scholar
Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz Syndrome (SLOS)
Ž. Korade, Libin Xu, F. Harrison, Refayat Ahsen +4 more
2013Biological Psychiatry53 citations Open access
Semantic Scholar
Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis.
Josi M. Herron, Rosalyn C Reese, K. Tallman, R. Narayanaswamy +2 more
2016Toxicological Sciences52 citations Open access
Semantic Scholar
Effect of psychotropic drug treatment on sterol metabolism
Ž. Korade, Wei Liu, E. B. Warren, Kristan Armstrong +2 more
2017Schizophrenia Research49 citations Open access
Semantic Scholar
7-Dehydrocholesterol-derived oxysterols and retinal degeneration in a rat model of Smith-Lemli-Opitz Syndrome
Libin Xu, L. Sheflin, N. Porter, S. Fliesler
2012Biochimica et Biophysica Acta49 citations Open access
Semantic Scholar
Sterols and Oxysterols in Plasma from Smith-Lemi-Opitz Syndrome Patients
W. Griffiths, J. Abdel-Khalik, P. J. Crick, M. Ogundare +11 more
2016Journal of Steroid Biochemistry and Molecular Biology46 citations Open access
Semantic Scholar
Unusual Kinetic Isotope Effects of Deuterium Reinforced Polyunsaturated Fatty Acids in Tocopherol-Mediated Free Radical Chain Oxidations
C. Lamberson, Libin Xu, H. Muchalski, J. R. Montenegro-Burke +6 more
2014Journal of the American Chemical Society45 citations Open access
Semantic Scholar
Superoxide reaction with tyrosyl radicals generates para-hydroperoxy and para-hydroxy derivatives of tyrosine.
Matías N. Möller, D. Hatch, Hye-Young H. Kim, N. Porter
2012Journal of the American Chemical Society45 citations
Semantic Scholar
Preparation and investigation of vitamin B6-derived aminopyridinol antioxidants.
Remigiusz A. Serwa, Tae-gyu Nam, L. Valgimigli, Sean M. Culbertson +4 more
2010Chemistry44 citations
Semantic Scholar
Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patients[S]
Wei Liu, Libin Xu, C. Lamberson, L. Merkens +4 more
2013Journal of Lipid Research41 citations Open access
Semantic Scholar
Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment
Thiago C. Genaro-Mattos, Luke B. Allen, Allison C. Anderson, K. Tallman +3 more
2019Molecular Psychiatry40 citations Open access
Semantic Scholar
Differential Cytotoxic Effects of 7-Dehydrocholesterol-derived Oxysterols on Cultured Retina-derived Cells: Dependence on Sterol Structure, Cell Type, and Density
B. A. Pfeffer, Libin Xu, N. Porter, Sriganesh Ramachandra Rao +1 more
2016Experimental Eye Research40 citations Open access
Semantic Scholar
Tyrosine-Lipid Peroxide Adducts from Radical Termination: Para-Coupling and Intramolecular Diels-Alder Cyclization
R. Shchepin, Matías N. Möller, Hye-Young H. Kim, D. Hatch +4 more
2010Journal of the American Chemical Society36 citations Open access
Semantic Scholar
Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis
Thiago C. Genaro-Mattos, K. Tallman, Luke B. Allen, Allison C. Anderson +3 more
2018Toxicology and Applied Pharmacology35 citations Open access
Semantic Scholar
Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis*
Jianhong Lu, Shu-Yuan Guo, Xinli Xue, Qun Chen +15 more
2017Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Propagation Rate Constants for the Peroxidation of Sterols on the Biosynthetic Pathway to Cholesterol
C. Lamberson, H. Muchalski, K. B. McDuffee, K. Tallman +2 more
2017Chemistry and Physics of Lipids34 citations Open access
Semantic Scholar
Activity-Based Probes linked with Laser-Cleavable Mass Tags for Signal Amplification in Imaging Mass Spectrometry: Analysis of Serine Hydrolase Enzymes in Mammalian Tissue
Jun-Hai Yang, P. Chaurand, J. L. Norris, N. Porter +1 more
2012Analytical Chemistry34 citations Open access
Semantic Scholar
Reactivities and Products of Free Radical Oxidation of Cholestadienols
Libin Xu, N. Porter
2014Journal of the American Chemical Society33 citations Open access
Semantic Scholar
Structure−Activity Analysis of Diffusible Lipid Electrophiles Associated with Phospholipid Peroxidation: 4-Hydroxynonenal and 4-Oxononenal Analogues
Colleen Mcgrath, K. Tallman, N. Porter, L. Marnett
2011Chemical Research in Toxicology33 citations Open access
Semantic Scholar
Prescription Medications Alter Neuronal and Glial Cholesterol Synthesis
K. Tallman, Luke B. Allen, Korinne B. Klingelsmith, Allison C. Anderson +4 more
2021ACS Chemical Neuroscience32 citations Open access
Semantic Scholar
Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target
William N. Beavers, Kristie L. Rose, J. Galligan, M. M. Mitchener +10 more
2017ACS Chemical Biology32 citations Open access
Semantic Scholar
Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome[S]
Katherine Windsor, Thiago C. Genaro-Mattos, Hye-Young H. Kim, Wei Liu +4 more
2013Journal of Lipid Research32 citations Open access
Semantic Scholar
Evaluating a targeted multiple reaction monitoring approach to global untargeted lipidomic analyses of human plasma
Mostafa J. Khan, Simona G. Codreanu, Sandeep Goyal, Phillip A. Wages +7 more
2020Rapid Communications in Mass Spectrometry29 citations Open access
Semantic Scholar
Peptidyl-prolyl cis/trans-Isomerase A1 (Pin1) Is a Target for Modification by Lipid Electrophiles
C. Aluise, Kristie L. Rose, M. Boiani, Michelle L. Reyzer +4 more
2012Chemical Research in Toxicology29 citations Open access
Semantic Scholar
Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles
N. Porter, Li-Bin Xu, D. Pratt
2020Chemistry28 citations Open access
Semantic Scholar
Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis
Thiago C. Genaro-Mattos, Allison C. Anderson, Luke B. Allen, K. Tallman +3 more
2020Molecular Psychiatry28 citations Open access
Semantic Scholar
Desmosterolosis and desmosterol homeostasis in the developing mouse brain
Luke B. Allen, Thiago C. Genaro-Mattos, N. Porter, K. Mirnics +1 more
2019Journal of Inherited Metabolic Disease28 citations Open access
Semantic Scholar
Competition H(D) Kinetic Isotope Effects in the Autoxidation of Hydrocarbons
H. Muchalski, Alexander J. Levonyak, Libin Xu, K. Ingold +1 more
2014Journal of the American Chemical Society28 citations Open access
Semantic Scholar
A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz syndrome[S]
Wei Liu, Libin Xu, C. Lamberson, D. Haas +2 more
2014Journal of Lipid Research27 citations Open access
Semantic Scholar
ω-Alkynyl Lipid Surrogates for Polyunsaturated Fatty Acids: Free Radical and Enzymatic Oxidations
William N. Beavers, Remigiusz A. Serwa, Yuki Shimozu, K. Tallman +4 more
2014Journal of the American Chemical Society27 citations Open access
Semantic Scholar
Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor
K. Tallman, Hye-Young H. Kim, Ž. Korade, Thiago C. Genaro-Mattos +3 more
2017Redox Biology26 citations Open access
Semantic Scholar
Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure[S]
Ž. Korade, Thiago C. Genaro-Mattos, K. Tallman, Wei Liu +5 more
2017Journal of Lipid Research25 citations Open access
Semantic Scholar
Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling
A. Speen, Hye-Young H. Kim, R. Bauer, Megan Meyer +6 more
2016Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS
L. Dantas, A. Chaves-Filho, F. Coelho, Thiago C. Genaro-Mattos +4 more
2018Redox Biology23 citations Open access
Semantic Scholar

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