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F. Harrison · SciRah

Researcher profile · Semantic Scholar

F. Harrison

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F. Harrison — researcher profile on SciRah

h-index: 29
Works: 64
Citations: 3,958

Most-cited papers

Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2)
F. Harrison, J. M. May
2009Free Radical Biology & Medicine667 citations Open access
Semantic Scholar
Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks
F. Harrison, A. Hosseini, M. P. McDonald
2008Behavioural Brain Research394 citations Open access
Semantic Scholar
Role of Vitamin C in the Function of the Vascular Endothelium
J. M. May, F. Harrison
2013Antioxidants and Redox Signaling323 citations Open access
Semantic Scholar
Spatial and nonspatial escape strategies in the Barnes maze.
F. Harrison, R. Reiserer, Andrew Tomarken, M. McDonald
2006Learning & memory (Cold Spring Harbor, N.Y.)229 citations Open access
Semantic Scholar
Brain manganese and the balance between essential roles and neurotoxicity
Rekha Balachandran, Somshuvra Mukhopadhyay, Dani McBride, Jennifer Veevers +4 more
2020Journal of Biological Chemistry223 citations Open access
Semantic Scholar
A critical review of Vitamin C for the prevention of age-related cognitive decline and Alzheimer’s disease
F. Harrison
2012Journal of Alzheimer's Disease166 citations Open access
Semantic Scholar
Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice.
Alexandra Bernardo, F. Harrison, M. McCord, Jiali Zhao +9 more
2009Neurobiology of Aging126 citations
Semantic Scholar
Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.
Gabriella Dicarlo, J. Aguilar, Heinrich J.G. Matthies, F. Harrison +9 more
2019Journal of Clinical Investigation125 citations Open access
Semantic Scholar
Vitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress in APP/PSEN1 and normally-aging mice
S. Dixit, Alexandra Bernardo, M. J. Walker, John A. Kennard +3 more
2015ACS Chemical Neuroscience122 citations Open access
Semantic Scholar
Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer’s Disease: Impacts on Cognitive Decline
Jennifer M. Walker, F. Harrison
2015Nutrients120 citations Open access
Semantic Scholar
Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer’s disease brain: a meta-analysis in human pathological specimens
M. Zabel, A. Nackenoff, W. Kirsch, F. Harrison +2 more
2017Free Radical Biology & Medicine103 citations Open access
Semantic Scholar
Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer’s disease
Jennifer M. Walker, S. Dixit, Anjelica C Saulsberry, J. M. May +1 more
2017Neurobiology of Disease102 citations Open access
Semantic Scholar
Vitamin C reduces spatial learning deficits in middle-aged and very old APP/PSEN1 transgenic and wild-type mice
F. Harrison, Asieh Hosseini, M. McDonald, J. M. May
2009Pharmacology, Biochemistry and Behavior102 citations Open access
Semantic Scholar
Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid
F. Harrison, Sarah S. Yu, Kristen L. Van Den Bossche, Li-Ying Li +2 more
2008Journal of Neurochemistry93 citations Open access
Semantic Scholar
Ascorbic Acid and the Brain: Rationale for the Use against Cognitive Decline
F. Harrison, G. Bowman, M. Polidori
2014Nutrients92 citations Open access
Semantic Scholar
New Insights on the Role of Manganese in Alzheimer’s Disease and Parkinson’s Disease
A. Martins, Patricia Morcillo, Omamuyouwi M. Ijomone, V. Venkataramani +4 more
2019International Journal of Environmental Research and Public Health85 citations Open access
Semantic Scholar
Low ascorbic acid and increased oxidative stress in gulo−/− mice during development
F. Harrison, M. Meredith, Sean M. Dawes, Jeanette L. Saskowski +1 more
2010Brain Research64 citations Open access
Semantic Scholar
Vitamin C distribution and retention in the mouse brain
F. Harrison, R. Green, Sean M. Dawes, J. M. May
2010Brain Research62 citations Open access
Semantic Scholar
Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer’s disease
T. Warner, Jing-Qiong Kang, John A. Kennard, F. Harrison
2014Epilepsy Research61 citations Open access
Semantic Scholar
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
S. Dixit, J. Fessel, F. Harrison
2017Free Radical Biology & Medicine53 citations Open access
Semantic Scholar
Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz Syndrome (SLOS)
Ž. Korade, Libin Xu, F. Harrison, Refayat Ahsen +4 more
2013Biological Psychiatry53 citations Open access
Semantic Scholar
Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma
Alexandra Bernardo-Colón, Victoria Vest, Adrienne Clark, Melissa L. Cooper +3 more
2018Cell Death and Disease50 citations Open access
Semantic Scholar
Longitudinal Consumption of Ergothioneine Reduces Oxidative Stress and Amyloid Plaques and Restores Glucose Metabolism in the 5XFAD Mouse Model of Alzheimer’s Disease
C. Whitmore, J. Haynes, W. Behof, Adam J Rosenberg +11 more
2022Pharmaceuticals47 citations Open access
Semantic Scholar
Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice
S. Davies, Christopher L. Bodine, E. Matafonova, Brooke G. Pantazides +6 more
2011Journal of Alzheimer's Disease47 citations Open access
Semantic Scholar
Altered DNA repair; an early pathogenic pathway in Alzheimer’s disease and obesity
Hao Yu, F. Harrison, F. Xia
2018Scientific Reports40 citations Open access
Semantic Scholar
Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics
S. K. Rao, Jordan M. Ross, F. Harrison, Alexandra Bernardo +4 more
2015Neurobiology of Disease36 citations Open access
Semantic Scholar
Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors
Shawniqua Williams-Roberson, S. Nwosu, E. Collar, A. Kiehl +8 more
2023JAMA Network Open35 citations Open access
Semantic Scholar
Cell-free hemoglobin augments acute kidney injury during experimental sepsis.
C. Shaver, M. Paul, N. Putz, S. Landstreet +8 more
2019AJP - Renal Physiology31 citations
Semantic Scholar
Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice
Deborah J Mi, S. Dixit, T. Warner, John A. Kennard +8 more
2018Neurobiology of Aging31 citations Open access
Semantic Scholar
Intravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice
John A. Kennard, F. Harrison
2014Behavioural Brain Research29 citations Open access
Semantic Scholar
Increased Expression of SVCT2 in a New Mouse Model Raises Ascorbic Acid in Tissues and Protects against Paraquat-Induced Oxidative Damage in Lung
F. Harrison, J. Best, M. Meredith, C. Gamlin +2 more
2012PLoS ONE24 citations Open access
Semantic Scholar
Epigenetic remodeling by vitamin C potentiates plasma cell differentiation
Heng-Yi Chen, Ana Almonte-Loya, Fang-Yun Lay, M. Hsu +9 more
2022eLife23 citations Open access
Semantic Scholar
Ascorbate deficiency decreases dopamine release in gulo–/– and APP/PSEN1 mice
D. Consoli, Lillian J. Brady, A. Bowman, Erin S. Calipari +1 more
2020Journal of Neurochemistry22 citations Open access
Semantic Scholar
Huntington’s Disease Genotype Suppresses Global Manganese-Responsive Processes in Pre-Manifest and Manifest YAC128 mice.
Anna C. Pfalzer, J. Wilcox, Simona G. Codreanu, Melissa S. Totten +11 more
2020Metallomics20 citations Open access
Semantic Scholar
Vitamin C is a source of oxoaldehyde and glycative stress in age‐related cataract and neurodegenerative diseases
Xingjun Fan, D. R. Sell, C. Hao, Sabrina Liu +7 more
2020Aging Cell19 citations Open access
Semantic Scholar
A Cecal Slurry Mouse Model of Sepsis Leads to Acute Consumption of Vitamin C in the Brain
D. Consoli, J. Jesse, Kelly R. Klimo, A. Tienda +3 more
2020Nutrients19 citations Open access
Semantic Scholar
Altered EEG, Disrupted Hippocampal Long-Term Potentiation and Neurobehavioral Deficits Implicate a Delirium-like state in a Mouse Model of Sepsis
D. Consoli, B. Spitznagel, Benjamin Owen, Hakmook Kang +6 more
2022Brain, behavior, and immunity17 citations Open access
Semantic Scholar
Autism-Associated Variant in the SLC6A3 Gene Alters the Oral Microbiome and Metabolism in a Murine Model
Gabriella Dicarlo, Samuel J. Mabry, Xixi Cao, C. McMillan +8 more
2021Frontiers in Psychiatry13 citations Open access
Semantic Scholar
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype
J. Wilcox, D. Consoli, K. Paffenroth, B. Spitznagel +3 more
2022Pharmacology, Biochemistry and Behavior12 citations Open access
Semantic Scholar
Effects of Acrylic Tunnel Enrichment on Anxiety-Like Behavior, Neurogenesis, and Physiology of C57BL/6J Mice.
Tai L Oatess, F. Harrison, L. Himmel, Carissa P. Jones
2020Journal of the American Association for Laboratory Animal Science12 citations Open access
Semantic Scholar
YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced behavioral and neuropathological changes
J. Wilcox, Anna C. Pfalzer, A. Tienda, Ines F Debbiche +5 more
2021Neurotoxicology10 citations Open access
Semantic Scholar
A novel antioxidant ergothioneine PET radioligand for in vivo imaging applications
W. Behof, C. Whitmore, J. Haynes, Adam J Rosenberg +5 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Oxidative Stress Levels in the Brain Are Determined by Post-Mortem Interval and Ante-Mortem Vitamin C State but Not Alzheimer’s Disease Status
Jared Eckman, S. Dixit, A. Nackenoff, M. Schrag +1 more
2018Nutrients10 citations Open access
Semantic Scholar
Combined Vitamin C & E deficiency induces motor defects in gulo−/−/SVCT2+/− mice
Marquicia R. Pierce, Danielle L Diasio, L. Rodrigues, F. Harrison +1 more
2012Nutritional neuroscience10 citations Open access
Semantic Scholar
Targeted and Untargeted Mass Spectrometry Reveals the Impact of High-Fat Diet on Peripheral Amino Acid Regulation in a Mouse Model of Alzheimer's Disease.
Amelia L. Taylor, D. E. Davis, Simona G. Codreanu, F. Harrison +2 more
2021Journal of Proteome Research8 citations
Semantic Scholar
Improved synthesis of an ergothioneine PET radioligand for imaging oxidative stress in Alzheimer’s disease
W. Behof, C. Whitmore, J. Haynes, Adam J Rosenberg +7 more
2022FEBS Letters7 citations Open access
Semantic Scholar
Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders
K. Ikeda, A. Tienda, F. Harrison, K. Kawakami
2021PLoS ONE5 citations Open access
Semantic Scholar
Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids
Houli Jiang, F. Harrison, Kavita S. Jain, S. Benjamin +6 more
2012Advances in Bioscience and Biotechnology5 citations Open access
Semantic Scholar
Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo
C. Meinke, M. Quinlan, K. Paffenroth, F. Harrison +5 more
2021Neurochemical Research3 citations Open access
Semantic Scholar
Behavioural and neurochemical effects of scurvy in gulo knockout mice
F. Harrison
20133 citations
Semantic Scholar

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J. M. May×8
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J. M. May — researcher profile on SciRah
A. Bowman×6
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S. Dixit×5
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D. Consoli×5
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John A. Kennard

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M. P. McDonald×3

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W. Behof — researcher profile on SciRah