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B. A. Pfeffer · SciRah

Researcher profile · Semantic Scholar

B. A. Pfeffer

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B. A. Pfeffer — researcher profile on SciRah

h-index: 24
Works: 55
Citations: 1,986

Most-cited papers

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro.
C. Hamel, E. Tsilou, B. A. Pfeffer, J. Hooks +2 more
1993Journal of Biological Chemistry329 citations Open access
Semantic Scholar
The presence of a soluble interphotoreceptor retinol‐binding protein (IRBP) in the retinal interphotoreceptor space
B. A. Pfeffer, B. Wiggert, L. Lee, B. Zonnenberg +2 more
1983Journal of Cellular Physiology151 citations
Semantic Scholar
Transforming growth factor beta 2 is the predominant isoform in the neural retina, retinal pigment epithelium-choroid and vitreous of the monkey eye.
B. A. Pfeffer, K. Flanders, C. Guerin, D. Danielpour +1 more
1994Experimental Eye Research145 citations
Semantic Scholar
Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution.
S. Becerra, R. Fariss, Yan Q. Wu, L. Montuenga +2 more
2004Experimental Eye Research136 citations Open access
Semantic Scholar
A developmentally regulated microsomal protein specific for the pigment epithelium of the vertebrate retina
C. Hamel, E. Tsilou, E. Harris, B. A. Pfeffer +3 more
1993Journal of Neuroscience Research128 citations
Semantic Scholar
Membrane receptors for retinol-binding protein in cultured human retinal pigment epithelium.
B. A. Pfeffer, V. Clark, John G. Flannery, Dean Bok
1986Investigative Ophthalmology and Visual Science95 citations
Semantic Scholar
Chapter 10 Improved methodology for cell culture of human and monkey retinal pigment epithelium
B. A. Pfeffer
199185 citations
Semantic Scholar
Evidence for an Insulin‐Like Growth Factor Autocrine‐Paracrine System in the Retinal Photoreceptor‐Pigment Epithelial Cell Complex
R. Waldbillig, B. A. Pfeffer, T. Schoen, Alice A. Adler +4 more
1991Journal of Neurochemistry83 citations
Semantic Scholar
Both rod and cone disc shedding are related to light onset in the cat.
Sreven K. Fisher, B. A. Pfeffer, Don H. Anderson
1983Investigative Ophthalmology and Visual Science72 citations
Semantic Scholar
Uptake, processing and release of retinoids by cultured human retinal pigment epithelium.
J. Flannery, W. O'day, B. A. Pfeffer, J. Horwitz +1 more
1990Experimental Eye Research61 citations
Semantic Scholar
Identification and localization of a beta-1 receptor from the integrin family in mammalian retinal pigment epithelial cells.
Don H. Anderson, Christopher J. Guerin, Brian Matsumoto, B. A. Pfeffer
1990Investigative Ophthalmology and Visual Science52 citations
Semantic Scholar
Ion-current-based Proteomic Profiling of the Retina in a Rat Model of Smith-Lemli-Opitz Syndrome*
Cheng-Jian Tu, Jun Li, Xiaosheng Jiang, L. Sheflin +4 more
2013Molecular & Cellular Proteomics49 citations Open access
Semantic Scholar
Detection of extracellular matrix molecules synthesized in vitro by monkey and human retinal pigment epithelium: influence of donor age and multiple passages.
David A. Newsome, B. A. Pfeffer, A. Hewitt, P. Robey +1 more
1988Experimental Eye Research49 citations
Semantic Scholar
Cell culture of retinal pigment epithelium: Special Issue.
B. A. Pfeffer, N. Philp
2014Experimental Eye Research48 citations
Semantic Scholar
Distribution of transforming growth factor‐β isoforms in the mammalian retina
Don H. Anderson, C. Guerin, G. Hageman, B. A. Pfeffer +1 more
199548 citations
Semantic Scholar
Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation
N. M. Gómez, Wen-Nan Lu, Jason C. Lim, K. Kiselyov +6 more
2017The FASEB Journal43 citations Open access
Semantic Scholar
Novel procedures for isolating intact retinal vascular beds from diabetic humans and animal models.
Nora Laver, W. Robison, B. A. Pfeffer
1993Investigative Ophthalmology and Visual Science43 citations
Semantic Scholar
Differential Cytotoxic Effects of 7-Dehydrocholesterol-derived Oxysterols on Cultured Retina-derived Cells: Dependence on Sterol Structure, Cell Type, and Density
B. A. Pfeffer, Libin Xu, N. Porter, Sriganesh Ramachandra Rao +1 more
2016Experimental Eye Research40 citations Open access
Semantic Scholar
The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions
J. H. Ma, J. Wang, Junhua Li, B. A. Pfeffer +2 more
2016Investigative Ophthalmology and Visual Science39 citations Open access
Semantic Scholar
Expression of transthyretin and retinol binding protein mRNAs and secretion of transthyretin by cultured monkey retinal pigment epithelium.
B. A. Pfeffer, S. Becerra, D. E. Borst, P. Wong
2004Molecular Vision39 citations
Semantic Scholar
Reassessing the suitability of ARPE-19 cells as a valid model of native RPE biology.
B. A. Pfeffer, S. Fliesler
2022Experimental Eye Research34 citations
Semantic Scholar
Clusterin protein diversity in the primate eye.
P. Wong, B. A. Pfeffer, S. L. Bernstein, M. L. Chambers +5 more
2000Molecular Vision33 citations
Semantic Scholar
Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome
Sriganesh Ramachandra Rao, B. A. Pfeffer, Néstor Más Gómez, L. Skelton +5 more
2018Autophagy30 citations Open access
Semantic Scholar
Mass spectrometry-based proteomics of oxidative stress: Identification of 4-hydroxy-2-nonenal (HNE) adducts of amino acids using lysozyme and bovine serum albumin as model proteins
Roshanak Aslebagh, B. A. Pfeffer, S. Fliesler, Costel C. Darie
2016Electrophoresis26 citations Open access
Semantic Scholar
Reduced myocilin expression in cultured monkey trabecular meshwork cells induced by a selective glucocorticoid receptor agonist: comparison with steroids.
B. A. Pfeffer, C. A. DeWitt, M. Salvador‐Silva, M. Cavet +2 more
2010Investigative Ophthalmology and Visual Science24 citations Open access
Semantic Scholar
Single-channel recordings from cultured human retinal pigment epithelial cells
J. A. Fox, B. A. Pfeffer, Gordon L. Fain
1988The Journal of General Physiology24 citations Open access
Semantic Scholar
Distribution of transforming growth factor-beta isoforms in the mammalian retina.
D. Anderson, C. Guerin, G. Hageman, B. A. Pfeffer +1 more
1995Journal of Neuroscience Research22 citations
Semantic Scholar
Monkey retinal pigment epithelial cells in vitro synthesize, secrete, and degrade insulin‐like growth factor binding proteins
R. Waldbillig, T. Schoen, G. Chader, B. A. Pfeffer
1992Journal of Cellular Physiology19 citations
Semantic Scholar
Development of retinal pigment epithelial surface structures ensheathing cone outer segments in the cat.
B. A. Pfeffer, Steven K. Fisher
1981Journal of Ultrastructure Research15 citations
Semantic Scholar
Streamlined Duplex Live-Dead Microplate Assay for Cultured Cells
B. A. Pfeffer, S. Fliesler
2017Experimental Eye Research10 citations Open access
Semantic Scholar
Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith–Lemli–Opitz Syndrome
B. A. Pfeffer, Li-Bin Xu, S. Fliesler
2021International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Decreased Myocilin Expression in Cultured Trabecular Meshwork Cells Induced by a Selective Glucocorticoid Receptor Agonist (SEGRA) Suggests an Improved Ocular Safety Profile Versus Steroids
B. A. Pfeffer, C. A. DeWitt, D. Meyer, M. Salvador‐Silva +3 more
20092 citations
Semantic Scholar
Preservation of structure and immunoreactivity at the vitreoretinal interface of the rabbit eye
B. A. Pfeffer, Steven Bernstein, S. P. Bartels
2006Graefe's Archive for Clinical and Experimental Ophthalmology2 citations
Semantic Scholar
Partial characterization of fucosylated cell surface glycoproteins of cultured RPE.
V. Clark, Xiao-Yan Zhou, B. A. Pfeffer
1990Current Eye Research2 citations
Semantic Scholar
Bisretinoid degradation and reduction of lipofuscin accumulation in the amelanotic retinal pigment epithelium of mammals with a tapetum
B. A. Pfeffer
2023Proceedings of the National Academy of Sciences of the United States of America1 citations Open access
Semantic Scholar
Up-regulation of ER and oxidative stress markers induced by oxysterols in a photoreceptor-derived cell line, with relevance to Smith-Lemli-Opitz syndrome
B. A. Pfeffer, Sriganesh Ramachandra Rao, Libin Xu, N. Porter +1 more
20151 citations
Semantic Scholar
Retina Proteome Profiling in a Rat Model of Smith-Lemli-Opitz Syndrome Using an Ion-Current-Based Method
Cheng-Jian Tu, Xiaosheng Jiang, J. Qu, L. Sheflin +3 more
20111 citations
Semantic Scholar
Considerations in monitoring autophagy in the neural retina: Utility of CAG-RFP-GFP-LC3 transgenic mice.
Sriganesh Ramachandra Rao, L. Skelton, B. A. Pfeffer, S. Fliesler
20190 citations
Semantic Scholar
Comparative proteomic profiling of cultured RPE cells derived from human embryonic stem cells vs. rhesus monkey
B. A. Pfeffer, Cheng-Jian Tu, Jun Li, J. Qu +1 more
20160 citations
Semantic Scholar
Compromised phagosome maturation underlies defective RPE clearance in an in vitro model of Smith-Lemli-Opitz Syndrome
Sriganesh Ramachandra Rao, N. M. Gómez, B. A. Pfeffer, Aryn M Rowsam +2 more
20160 citations
Semantic Scholar
Selective ablation of dehydrodolichyl diphosphate synthase (Dhdds) expression in RPE alters retinal structure and function
Stephanie J. Davis, Marci L. DeRamus, B. A. Pfeffer, Sriganesh Ramachandra Rao +3 more
20160 citations
Semantic Scholar
Effects of blast overpressure on the retina in a rat model of primary blast injury
S. Fliesler, B. A. Pfeffer, M. Prunty, M. Pardue
20160 citations
Semantic Scholar
Understanding the molecular mechanism of RPE pathology in Smith-Lemli-Opitz Syndrome
Sriganesh Ramachandra Rao, B. A. Pfeffer, Meerim Choi, K. Francis +2 more
20150 citations
Semantic Scholar
Transcriptomic analysis of oxysterol effects on a photoreceptor-derived cell line, with relevance to Smith-Lemli-Opitz syndrome
B. A. Pfeffer, P. Wong, Libin Xu, Zi-Hua Hu +4 more
20140 citations
Semantic Scholar
Elevated ocular A2E and bis-retinoid levels in a rat model of Smith-Lemli-Opitz syndrome
S. Fliesler, C. Goulah, B. A. Pfeffer, K. Ueda +1 more
20140 citations
Semantic Scholar
In Vitro Toxicity of 7-Dehydrocholesterol-Derived Oxysterols Depends on Retinal Cell Type
B. A. Pfeffer, Libin Xu, N. Porter, S. Fliesler
20130 citations
Semantic Scholar
Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome is Caspase-Independent, and Involves Cathepsin D Upregulation
M. Behringer, B. A. Pfeffer, S. Fliesler
20120 citations
Semantic Scholar
7-Dehydrocholesterol-derived Oxysterols are Differentially Cytotoxic to 661W Photoreceptor Cells
B. A. Pfeffer, Priyanka Patel, Libin Xu, N. Porter +1 more
20120 citations
Semantic Scholar
Association of the Complement Pathway with Retinal Degeneration in the AY9944-Induced Rat Model of Smith-Lemli-Opitz Syndrome
L. Sheflin, Joyce E. Young, B. A. Pfeffer, S. Fliesler
20110 citations
Semantic Scholar
Human Optic Nerve Astrocytes as an in vitro Model of Inflammation and Oxidative Stress in the Eye
M. Salvador‐Silva, K. VanDerMeid, B. A. Pfeffer
20080 citations
Semantic Scholar

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