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A. Agathanggelou · SciRah

Researcher profile · Semantic Scholar

A. Agathanggelou

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A. Agathanggelou — researcher profile on SciRah

h-index: 33
Works: 81
Citations: 5,174

Most-cited papers

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
A. Agathanggelou, S. Honorio, D. Macartney, Alonso Martínez +11 more
2001Oncogene419 citations Open access
Semantic Scholar
Role of the Ras-association domain family 1 tumor suppressor gene in human cancers.
A. Agathanggelou, W. Cooper, F. Latif
2005Cancer Research418 citations Open access
Semantic Scholar
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M. Zimmermann, O. Murina, Martin A. M. Reijns, A. Agathanggelou +20 more
2018Nature373 citations Open access
Semantic Scholar
Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia.
O. Goodyear, A. Agathanggelou, Igor Novitzky-Basso, S. Siddique +7 more
2010Blood343 citations
Semantic Scholar
ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.
M. Kwok, N. Davies, A. Agathanggelou, E. Smith +11 more
2016Blood260 citations
Semantic Scholar
EPSTEIN–BARR VIRUS (EBV) INFECTION IN INFECTIOUS MONONUCLEOSIS: VIRUS LATENCY, REPLICATION AND PHENOTYPE OF EBV‐INFECTED CELLS
G. Niedobitek, A. Agathanggelou, H. Herbst, L. Whitehead +2 more
1997Journal of Pathology245 citations
Semantic Scholar
Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma.
C. Morrissey, Alonso Martínez, M. Zatyka, A. Agathanggelou +10 more
2001Cancer Research215 citations
Semantic Scholar
Frequent expression of interleukin-10 by Epstein-Barr virus-harboring tumor cells of Hodgkin's disease.
H. Herbst, H. Foss, Jens Samol, I. Araujo +5 more
1996Blood202 citations Open access
Semantic Scholar
Heterogeneous expression of Epstein-Barr virus latent proteins in endemic Burkitt's lymphoma.
G. Niedobitek, A. Agathanggelou, M. Rowe, E. Jones +5 more
1995Blood165 citations
Semantic Scholar
RASSF1A Interacts with Microtubule-Associated Proteins and Modulates Microtubule Dynamics
A. Dallol, A. Agathanggelou, S. Fenton, J. Ahmed-Choudhury +6 more
2004Cancer Research155 citations Open access
Semantic Scholar
RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours
D. Astuti, A. Agathanggelou, S. Honorio, A. Dallol +9 more
2001Oncogene145 citations Open access
Semantic Scholar
Expression of immune regulatory molecules in Epstein-Barr virus-associated nasopharyngeal carcinomas with prominent lymphoid stroma. Evidence for a functional interaction between epithelial tumor cells and infiltrating lymphoid cells.
A. Agathanggelou, G. Niedobitek, Ren-Sheng Chen, J. Nicholls +2 more
1995American Journal of Pathology136 citations
Semantic Scholar
Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours
S. Honorio, A. Agathanggelou, N. Wernert, M. Rothe +2 more
2003Oncogene131 citations
Semantic Scholar
Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patients
S. Honorio, A. Agathanggelou, M. Schuermann, W. Pankow +3 more
2003Oncogene124 citations Open access
Semantic Scholar
The association of squamous cell carcinomas of the nasopharynx with Epstein–Barr virus shows geographical variation reminiscent of Burkitt's lymphoma
J. Nicholls, A. Agathanggelou, K. Fung, Xiang-Guo Zeng +1 more
1997Journal of Pathology112 citations
Semantic Scholar
Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers
A. Agathanggelou, A. Dallol, S. Zöchbauer-Müller, C. Morrissey +9 more
2003Oncogene107 citations Open access
Semantic Scholar
Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma.
R. Hogg, S. Honorio, Alonso Martínez, A. Agathanggelou +6 more
2002European Journal of Cancer103 citations
Semantic Scholar
Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma.
A. Agathanggelou, I. Bièche, J. Ahmed-Choudhury, B. Nicke +7 more
2003Cancer Research99 citations
Semantic Scholar
P53 overexpression and Epstein‐Barr virus infection in undifferentiated and squamous cell nasopharyngeal carcinomas
G. Niedobitek, A. Agathanggelou, P. Barber, L. Smallman +2 more
1993Journal of Pathology98 citations
Semantic Scholar
Involvement of the RASSF1A tumor suppressor gene in controlling cell migration.
A. Dallol, A. Agathanggelou, Stella Tommasi, G. Pfeifer +2 more
2005Cancer Research95 citations
Semantic Scholar
Inhibition of Human Breast Carcinoma Growth by a Soluble Recombinant Human CD40 Ligand
A. Hirano, D. Longo, D. Taub, D. Ferris +7 more
199991 citations
Semantic Scholar
BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia
D. da Costa, A. Agathanggelou, T. Perry, V. Weston +10 more
2013Blood Cancer Journal90 citations Open access
Semantic Scholar
Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma.
G. Niedobitek, A. Agathanggelou, J. Nicholls
1996Seminars in Cancer Biology89 citations
Semantic Scholar
Identification of the E1A-Regulated Transcription Factor p120E4F as an Interacting Partner of the RASSF1A Candidate Tumor Suppressor Gene
S. Fenton, A. Dallol, A. Agathanggelou, L. Hesson +8 more
2004Cancer Research86 citations
Semantic Scholar
Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand.
A. Hirano, D. Longo, D. Taub, D. Ferris +7 more
1999Blood84 citations
Semantic Scholar
Epstein-Barr virus (EBV) in infectious mononucleosis: detection of the virus in tonsillar B lymphocytes but not in desquamated oropharyngeal epithelial cells
G. Niedobitek, A. Agathanggelou, N. Steven, L. Young
2000Molecular Pathology82 citations Open access
Semantic Scholar
Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway.
M. Kwok, N. Davies, A. Agathanggelou, E. Smith +5 more
2015The Lancet77 citations
Semantic Scholar
USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.
A. Agathanggelou, E. Smith, N. Davies, M. Kwok +19 more
2017Blood67 citations Open access
Semantic Scholar
Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma
P. Murray, Guo-Hua Qiu, L. Fu, Elyse R Waites +12 more
2004Oncogene65 citations Open access
Semantic Scholar
Depletion of the Ras association domain family 1, isoform A-associated novel microtubule-associated protein, C19ORF5/MAP1S, causes mitotic abnormalities.
A. Dallol, W. Cooper, F. Al-Mulla, A. Agathanggelou +2 more
2007Cancer Research57 citations Open access
Semantic Scholar
Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter.
J. Ahmed-Choudhury, A. Agathanggelou, S. Fenton, C. Ricketts +3 more
2005Cancer Research47 citations Open access
Semantic Scholar
Non‐Hodgkin's lymphoma, coeliac disease, and Epstein–Barr virus: A study of 13 cases of enteropathy‐associated T‐ and B‐cell lymphoma
M. Ilyas, G. Niedobitek, A. Agathanggelou, R. Barry +4 more
1995Journal of Pathology41 citations
Semantic Scholar
Latent Epstein-Barr virus infection in cottontop tamarins. A possible model for Epstein-Barr virus infection in humans.
G. Niedobitek, A. Agathanggelou, S. Finerty, R. Tierney +5 more
1994American Journal of Pathology37 citations
Semantic Scholar
TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target.
E. Kennedy, E. Coulter, E. Halliwell, N. Profitós-Pelejà +19 more
2021Blood32 citations Open access
Semantic Scholar
Epigenetic Inactivation of the RASSF 1 A 3 p 21 . 3 Tumor Suppressor Gene in Both Clear Cell and Papillary Renal Cell Carcinoma 1
C. Morrissey, Alonso Martínez, M. Zatyka, A. Agathanggelou +10 more
200132 citations
Semantic Scholar
DNA damage response defects in hematologic malignancies: mechanistic insights and therapeutic strategies.
M. Kwok, A. Agathanggelou, T. Stankovic
2024Blood26 citations Open access
Semantic Scholar
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
M. Kwok, C. Oldreive, A. Rawstron, Anshita Goel +26 more
2019Blood24 citations Open access
Semantic Scholar
Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response.
Eliot Marston, V. Weston, Jenny Jesson, Esther N. Maina +11 more
2009Blood23 citations Open access
Semantic Scholar
Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection
Nafiseh Chalabi Hagkarim, Ellis L. Ryan, P. Byrd, R. Hollingworth +8 more
2018Journal of Virology21 citations Open access
Semantic Scholar
Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants
A. Agathanggelou, V. Weston, T. Perry, N. Davies +17 more
2015Haematologica20 citations Open access
Semantic Scholar
Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia
Xingjian Li, Daniel T. Payne, B. Ampolu, N. Bland +20 more
2019MedChemComm18 citations Open access
Semantic Scholar
Direct demonstration of persistent Epstein-Barr virus gene expression in peripheral blood of infected common marmosets and analysis of virus-infected tissues in vivo.
Paul J. Farrell, Martine Hollyoake, Gerald Niedobitek, A. Agathanggelou +2 more
1997Journal of General Virology18 citations Open access
Semantic Scholar
Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives
M. Kwok, A. Agathanggelou, N. Davies, T. Stankovic
2021Cancers16 citations Open access
Semantic Scholar
Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts
N. Davies, M. Kwok, C. Gould, C. Oldreive +9 more
2017OncoTarget15 citations Open access
Semantic Scholar
The expression of variant CD44 in nasopharyngeal carcinoma is unrelated to expression of LMP-1.
L. Brooks, G. Niedobitek, A. Agathanggelou, P. Farrell
1995American Journal of Pathology11 citations
Semantic Scholar
Identification of the E 1 A-Regulated Transcription Factor p 120 E 4 F as an Interacting Partner of the RASSF 1 A Candidate Tumor Suppressor Gene
S. Fenton, A. Dallol, A. Agathanggelou, L. Hesson +8 more
200410 citations
Semantic Scholar
T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice
C. Oldreive, A. Skowrońska, N. Davies, H. Parry +12 more
2015Disease Models & Mechanisms8 citations Open access
Semantic Scholar
Transcriptional Regulation of Cyclin A 2 by RASSF 1 A through the Enhanced Binding of p 120 E 4 F to the Cyclin A 2 Promoter
J. Ahmed-Choudhury, A. Agathanggelou, S. Fenton, C. Ricketts +3 more
20058 citations
Semantic Scholar
Aniline-containing derivatives of parthenolide: Synthesis and anti-chronic lymphocytic leukaemia activity
Alex S. Quy, Xingjian Li, L. Male, T. Stankovic +2 more
2020Tetrahedron6 citations Open access
Semantic Scholar
Epigenetic Manipulation of Cancer Testis Antigen (CTA) Expression: A Strategy for Manipulating the Graft-Versus Leukaemia Response in Patients Allografted for Haematological Malignancies
T. Stankovic, A. McLarnon, A. Agathanggelou, O. Goodyear +2 more
20085 citations
Semantic Scholar

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F. Latif×18
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F. Latif — researcher profile on SciRah
E. Maher×16
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T. Stankovic×15
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G. Niedobitek×11
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A. Dallol — researcher profile on SciRah

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S. Honorio — researcher profile on SciRah

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M. Kwok — researcher profile on SciRah

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C. Oldreive — researcher profile on SciRah

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E. Smith — researcher profile on SciRah