Researcher profile · Semantic Scholar

Nirav R. Kapadia

h-index: 9
Works: 21
Citations: 253

Most-cited papers

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop
Megan J. Agajanian, M. Walker, Alison D. Axtman, Roberta R. Ruela de Sousa +23 more
2019Cell Reports82 citations Open access
Semantic Scholar
SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.
C. Wells, R. Couñago, Juanita C. Limas, T. L. Almeida +14 more
2019ACS Medicinal Chemistry Letters38 citations Open access
Semantic Scholar
In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the nek family of kinases
C. Wells, Nirav R. Kapadia, R. Couñago, D. Drewry
2017bioRxiv21 citations Open access
Semantic Scholar
Evaluation of structural effects on 5-HT2A receptor antagonism by aporphines: identification of a new aporphine with 5-HT2A antagonist activity
S. Ponnala, Junior A Gonzales, Nirav R. Kapadia, H. Navarro +1 more
2014Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function
Phillippa J. Carling, Brent J. Ryan, William McGuinness, Shikha Kataria +8 more
2022Autophagy17 citations Open access
Semantic Scholar
Aporphine Alkaloids as Ligands for Serotonin Receptors
Nirav R. Kapadia, W. Harding
201617 citations Open access
Semantic Scholar
NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells
M. Matossian, S. Elliott, T. Van Hoang, H. Burks +17 more
2021Breast Cancer Research and Treatment14 citations Open access
Semantic Scholar
C4 phenyl aporphines with selective h5-HT2B receptor affinity
Nirav R. Kapadia, W. Harding
2015Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Synthesis and evaluation of aporphine analogues containing C1 allyl isosteres at the h5-HT2A receptor
S. Ponnala, Nirav R. Kapadia, Sudharshan Madapa, I. Alberts +1 more
2015Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
APORPHINOID ANTAGONISTS OF 5-HT2A RECEPTORS: FURTHER EVALUATION OF RING A SUBSTITUENTS AND THE SIZE OF RING C
S. Ponnala, Nirav R. Kapadia, H. A. Navarro, W. Harding
2014Chemical Biology and Drug Design9 citations Open access
Semantic Scholar
Facile synthesis of 4,5,6a,7-tetrahydrodibenzo[de,g]chromene heterocycles and their transformation to phenanthrene alkaloids
Nirav R. Kapadia, W. Harding
2013Tetrahedron6 citations Open access
Semantic Scholar
Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline
Meganathan Nandakumar, Anja R Ollodart, Neil Fleck, Nirav R. Kapadia +7 more
2023Journal of Medicinal Chemistry4 citations Open access
Semantic Scholar
Identification of tris-(phenylalkyl)amines as new selective h5-HT2B receptor antagonists
S. Ponnala, Nirav R. Kapadia, W. Harding
20154 citations
Semantic Scholar
New halogenated tris-(phenylalkyl)amines as h5-HT2B receptor ligands.
Nirav R. Kapadia, Shahrear Ahmed, W. Harding
2016Bioorganic & Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6
Megan J. Agajanian, M. Walker, Alison D. Axtman, Roberta R. Ruela de Sousa +20 more
2018bioRxiv1 citations Open access
Semantic Scholar
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple negative breast cancer to identify targetable signaling pathways
M. Matossian, H. Burks, S. Elliott, Van T. Hoang +19 more
2020Anti-Cancer Drugs0 citations Open access
Semantic Scholar
A Transcription-uncoupled Negative Feedback Loop for the 1 WNT Pathway: WNT Activates the AAK1 Kinase to Promote Clathrin-mediated Endocytosis of LRP6
Megan J. Agajanian, M. Walker, Alison D. Axtman, Roberta R. Ruela de Sousa +21 more
20180 citations
Semantic Scholar
Synthesis of Novel Aporphine-Inspired Neuroreceptor Ligands
Nirav R. Kapadia
20160 citations
Semantic Scholar
Correction: Identification of tris-(phenylalkyl)amines as new selective h5-HT2B receptor antagonists
S. Ponnala, Nirav R. Kapadia, W. Harding
20150 citations Open access
Semantic Scholar
Facile Synthesis of 4,5,6a,7-Tetrahydrodibenzo[de,g]chromene Heterocycles and Their Transformation to Phenanthrene Alkaloids.
Nirav R. Kapadia, W. Harding
20140 citations
Semantic Scholar
Synthesis of potential CNS ligands via structural exploration of aporphines
Nirav R. Kapadia, W. Harding
20130 citations
Semantic Scholar

R. Couñago

×5

S. Ponnala×5

Alison D. Axtman×4

Roberta R. Ruela de Sousa×4

O. Gileadi×4

T. Willson×4

Megan J. Agajanian×3

M. Walker×3