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E. Lee · SciRah

Researcher profile · Semantic Scholar

E. Lee

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E. Lee — researcher profile on SciRah

h-index: 26
Works: 65
Citations: 3,130

Most-cited papers

Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment
E. Lee, Stephen Ryan, B. Birmingham, Julie A. Zalikowski +6 more
2005Clinical pharmacology and therapy500 citations
Semantic Scholar
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations.
Kun Tang, S. Ngoi, Pai-Chung Gwee, John M Z Chua +3 more
2002Pharmacogenetics (London)305 citations
Semantic Scholar
Herbal bioactivation: The good, the bad and the ugly
Shu-Feng Zhou, H. Koh, Yi-Huai Gao, Z. Gong +1 more
2003Life Science264 citations Open access
Semantic Scholar
Pharmacokinetic Interactions of Drugs with St John’s Wort
Shu-Feng Zhou, E. Chan, S. Pan, Min Huang +1 more
2004Journal of Psychopharmacology235 citations Open access
Semantic Scholar
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations.
Yik Y. Teo, X. Sim, R. Ong, Adrian K S Tan +7 more
2009Genome Research180 citations Open access
Semantic Scholar
Frequency of C3435T single nucleotide MDR1 genetic polymorphism in an Asian population: phenotypic-genotypic correlates.
C. Balram, Amarnath Sharma, C. Sivathasan, E. Lee
2003British Journal of Clinical Pharmacology129 citations Open access
Semantic Scholar
The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance
J. Sarathy, V. Dartois, E. Lee
2012Pharmaceuticals111 citations Open access
Semantic Scholar
Genomic evidence for recent positive selection at the human MDR1 gene locus.
Kun Tang, L. Wong, E. Lee, S. Chong +1 more
2004Human Molecular Genetics103 citations Open access
Semantic Scholar
Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations.
N. Pillai, Y. Okada, Woei-Yuh Saw, R. Ong +21 more
2014Human Molecular Genetics97 citations
Semantic Scholar
In silico SNP analysis and bioinformatics tools: a review of the state of the art to aid drug discovery.
James Mah, E. S. H. Low, E. Lee
2011Drug Discovery Today71 citations
Semantic Scholar
Eltrombopag increases plasma rosuvastatin exposure in healthy volunteers.
A. Allred, C. Bowen, J. Park, B. Peng +3 more
2011British Journal of Clinical Pharmacology70 citations Open access
Semantic Scholar
Proton Pump Inhibitors
K. Fock, T. Ang, Lean Choo Bee, E. Lee
2008Clinical Pharmacokinetics66 citations
Semantic Scholar
GLUTATHIONE S-TRANSFERASE THETA (GSTT1) GENETIC POLYMORPHISM AMONG CHINESE, MALAYS AND INDIANS IN INGAPORE
E. Lee, J. Wong, P. Yeoh, N. H. Gong
199564 citations
Semantic Scholar
Genetic polymorphisms of UDP-glucuronosyltransferase in Asians: UGT1A1*28 is a common allele in Indians.
C. Balram, K. Sabapathy, Gao Fei, K. Khoo +1 more
2002Pharmacogenetics (London)62 citations
Semantic Scholar
A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection.
Zi-Hua Wang, Baoshuang Wang, Kun Tang, E. Lee +2 more
2005Human Molecular Genetics51 citations
Semantic Scholar
Oral sulfasalazine as a clinical BCRP probe substrate: pharmacokinetic effects of genetic variation (C421A) and pantoprazole coadministration.
K. Adkison, S. Vaidya, Daniel Y. Lee, S. Koo +7 more
2010Journal of Pharmacy and Science49 citations
Semantic Scholar
The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects.
K. Adkison, S. Vaidya, Daniel Y. Lee, S. Koo +6 more
2008British Journal of Clinical Pharmacology48 citations Open access
Semantic Scholar
Genetic polymorphisms in KCNQ1, HERG, KCNE1 and KCNE2 genes in the Chinese, Malay and Indian populations of Singapore.
S. Koo, Wo-On-Fei Ho, E. Lee
2006British Journal of Clinical Pharmacology36 citations Open access
Semantic Scholar
PHARMACOGENETICS APPROACH TO THERAPEUTICS
S. Koo, E. Lee
2006Clinical and Experimental Pharmacology and Physiology34 citations Open access
Semantic Scholar
Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in Singapore populations.
D. Toh, Florence S. G. Cheung, M. Murray, Tanel Pern +2 more
2013Molecular Pharmaceutics33 citations
Semantic Scholar
Effects of proton pump inhibitor on the human gut microbiome profile in multi-ethnic groups in Singapore.
S. Koo, Jing-min Deng, D. Ang, J. Hsiang +9 more
2019Singapore medical journal30 citations Open access
Semantic Scholar
SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome
P. Makarawate, N. Chaosuwannakit, S. Vannaprasaht, Dujdao Sahasthas +6 more
2017Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease29 citations Open access
Semantic Scholar
Predicting chemotherapeutic drug combinations through gene network profiling
Thi Thuy Trang Nguyen, J. Chua, K. Seah, S. Koo +10 more
2016Scientific Reports27 citations Open access
Semantic Scholar
Genomic copy number variations in three Southeast Asian populations
C. Ku, Y. Pawitan, X. Sim, R. Ong +5 more
2010Human Mutation27 citations
Semantic Scholar
Polyamines Inhibit Porin-Mediated Fluoroquinolone Uptake in Mycobacteria
J. Sarathy, E. Lee, V. Dartois
2013PLoS ONE26 citations Open access
Semantic Scholar
Simultaneous genotyping of seven single-nucleotide polymorphisms in the MDR1 gene by single-tube multiplex minisequencing.
Pai-Chung Gwee, Kun Tang, John M Z Chua, E. Lee +2 more
2003Clinical Chemistry26 citations
Semantic Scholar
Polyethylene-co-acrylic acid as coating for biosensor application: A quartz crystal microbalance study
Kok-Ting Chong, Xiao-Di Su, E. Lee, S. O'Shea
200225 citations
Semantic Scholar
Genetic Variability of Arylalkylamine-N-Acetyl-Transferase (AA-NAT) Gene and Human Sleep/Wake Pattern
Grace Wang, C. G. Lee, E. Lee
2004Chronobiology International24 citations
Semantic Scholar
Towards exploratory hypothesis testing and analysis
Gui-Mei Liu, Mengling Feng, Yue Wang, L. Wong +3 more
2011IEEE International Conference on Data Engineering23 citations
Semantic Scholar
Genetic variations of the SLCO1B1 gene in the Chinese, Malay and Indian populations of Singapore.
Wo-On-Fei Ho, S. Koo, Jie-Yin Yee, E. Lee
2008Drug Metabolism and Pharmacokinetics23 citations
Semantic Scholar
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK‐mTOR signalling
K. Seah, Jian Yun Loh, Thi Thuy Trang Nguyen, Hwei Ling Tan +7 more
2018Experimental Cell Research21 citations
Semantic Scholar
Genetic variations of the SLC22A5 gene in the Chinese and Indian populations of Singapore.
D. Toh, Jie-Yin Yee, S. Koo, M. Murray +1 more
2010Drug Metabolism and Pharmacokinetics21 citations
Semantic Scholar
Genetic variability of RyR2 and CASQ2 genes in an Asian population.
Chang-Hua Wong, S. Koo, George Qiongze She, P. Chui +1 more
2009Forensic Science International18 citations
Semantic Scholar
Role of membrane transporters in the safety profile of drugs
E. Lee, C. Lean, L. M. G. Limenta
2009Expert Opinion on Drug Metabolism & Toxicology18 citations
Semantic Scholar
Role of multi-drug resistance-associated protein-1 transporter in statin-induced myopathy.
Rajkumar s/o Dorajoo, B. Pereira, Yu Zou, P. Gopalakrishnakone +3 more
2008Life Science18 citations
Semantic Scholar
Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects.
D. Toh, L. M. G. Limenta, Jie-Yin Yee, Ling-Zhi Wang +3 more
2013British Journal of Clinical Pharmacology17 citations Open access
Semantic Scholar
Genetic variations in the MCT1 (SLC16A1) gene in the Chinese population of Singapore.
C. Lean, E. Lee
2009Drug Metabolism and Pharmacokinetics17 citations
Semantic Scholar
Functional analysis of pharmacogenetic variants of human organic cation/carnitine transporter 2 (hOCTN2) identified in Singaporean populations.
D. Toh, M. Murray, Kuan Pern Tan, Vishwaroop B. Mulay +3 more
2011Biochemical Pharmacology16 citations
Semantic Scholar
Pharmacogenetics of CYP1A2, novel polymorphisms and haplotypes in three distinct Asian populations.
J. Lim, O. Singh, R. Ramasamy, Saminathan Ramasamy +3 more
2010Drug Metabolism and Pharmacokinetics16 citations
Semantic Scholar
Effect of Dietary Purines on the Pharmacokinetics of Orally Administered Ribavirin
Ling-Hui Li, S. Koo, Lie Michael George Limenta, Li-mei Han +3 more
2009Journal of clinical pharmacology16 citations
Semantic Scholar
Genetic variations of the SLC22A4 gene in Chinese and Indian populations of Singapore.
D. Toh, S. Koo, L. M. G. Limenta, Jie-Yin Yee +2 more
2009Drug Metabolism and Pharmacokinetics16 citations
Semantic Scholar
A pilot study to examine the association between human gut microbiota and the host's central obesity
S. Koo, C. Chu, J. Khoo, M. Cheong +8 more
2019JGH Open15 citations Open access
Semantic Scholar
Identification and functional analysis of variants in the human concentrative nucleoside transporter 2, hCNT2 (SLC28A2) in Chinese, Malays and Indians.
Ling-Hui Li, Cherine Meng Fong Tan, S. Koo, Kok-Ting Chong +1 more
2007Pharmacogenetics & Genomics15 citations
Semantic Scholar
Interethnic differences of PEPT2 (SLC15A2) polymorphism distribution and associations with cephalexin pharmacokinetics in healthy Asian subjects
R. Liu, A. Tang, Y. Tan, L. M. G. Limenta +1 more
2008European Journal of Clinical Pharmacology14 citations
Semantic Scholar
P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells.
Zoey Tay, S. Koo, T. Nguyen, Tsu-Soo Tan +7 more
2013Current Medicinal Chemistry13 citations
Semantic Scholar
Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims
Birendranath Banerjee, D. Peiris, S. Koo, P. Chui +2 more
2009Cytogenetic and Genome Research13 citations
Semantic Scholar
Effects of sodium bicarbonate and ammonium chloride pre-treatments on PEPT2 (SLC15A2) mediated renal clearance of cephalexin in healthy subjects.
Rui Liu, A. Tang, Y. Tan, L. M. G. Limenta +1 more
2011Drug Metabolism and Pharmacokinetics10 citations
Semantic Scholar
Multiplexed genotyping of ABC transporter polymorphisms with the Bioplex suspension array
S. Koo, Ching-Ong Tan, Kok-Ting Chong, C. G. Lee +2 more
2007Biological Procedures Online10 citations Open access
Semantic Scholar
Distribution of the FcgammaRIIIa 176 F/V polymorphism amongst healthy Chinese, Malays and Asian Indians in Singapore.
Kok-Ting Chong, Wo-On-Fei Ho, S. Koo, P. Thompson +1 more
2007British Journal of Clinical Pharmacology10 citations Open access
Semantic Scholar
Pharmacogenetics of the Human MDR1 Multidrug Transporter
Caroline G. L. Lee, S. Chong, E. Lee
200410 citations
Semantic Scholar

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S. Koo×19
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S. Koo — researcher profile on SciRah
S. Chong×5
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S. Chong — researcher profile on SciRah
D. Toh×5
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D. Toh — researcher profile on SciRah
M. Murray×5
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M. Murray — researcher profile on SciRah

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Jie-Yin Yee — researcher profile on SciRah

L. M. G. Limenta×5

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Kun Tang — researcher profile on SciRah

Caroline G. L. Lee×4

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Caroline G. L. Lee — researcher profile on SciRah

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Ling-Hui Li — researcher profile on SciRah

Kok-Ting Chong×4

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Kok-Ting Chong — researcher profile on SciRah

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Yik Y. Teo — researcher profile on SciRah

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R. Ong — researcher profile on SciRah