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T. Nguyen · SciRah

Researcher profile · Semantic Scholar

T. Nguyen

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T. Nguyen — researcher profile on SciRah

h-index: 23
Works: 47
Citations: 1,613

Most-cited papers

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair
B. Vazquez, Joshua K. Thackray, Nicolás G. Simonet, Noriko Kane-Goldsmith +6 more
2016EMBO Journal252 citations Open access
Semantic Scholar
Dissecting the treatment-naïve ecosystem of human melanoma brain metastasis
Jana Biermann, Johannes C. Melms, A. Amin, Yi-Ping Wang +55 more
2022Cell177 citations Open access
Semantic Scholar
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
T. Nguyen, Yiru Zhang, En-Yuan Shang, C. Shu +15 more
2020Journal of Clinical Investigation165 citations Open access
Semantic Scholar
Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma
T. Nguyen, En-Yuan Shang, C. Shu, Sungsoo Kim +12 more
2021Nature Communications90 citations Open access
Semantic Scholar
Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis
N. Popgeorgiev, Jaison D. Sa, L. Jabbour, S. Banjara +12 more
2020Science Advances78 citations Open access
Semantic Scholar
Telomere biology disorders
Michelle Li Wei Kam, T. Nguyen, J. Ngeow
2021npj Genomic Medicine73 citations Open access
Semantic Scholar
Metabolic Reprogramming by Dual AKT/ERK Inhibition Through Imipridones Elicits Unique Vulnerabilities in Glioblastoma
C. Ishida, Yiru Zhang, E. Bianchetti, C. Shu +9 more
2018Clinical Cancer Research72 citations Open access
Semantic Scholar
Caspases in the Developing Central Nervous System: Apoptosis and Beyond
T. Nguyen, G. Gillet, N. Popgeorgiev
2021Frontiers in Cell and Developmental Biology71 citations Open access
Semantic Scholar
Novel IDH1 Targeted Glioma Therapies
G. Karpel-Massler, T. Nguyen, En-Yuan Shang, M. Siegelin
2019CNS Drugs68 citations Open access
Semantic Scholar
Midkine regulates pleiotrophin organ-specific gene expression: evidence for transcriptional regulation and functional redundancy within the pleiotrophin/midkine developmental gene family.
G. Herradón, L. Ezquerra, T. Nguyen, I. Silos-santiago +1 more
2005Biochemical and Biophysical Research Communications - BBRC52 citations
Semantic Scholar
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition
T. Nguyen, C. Ishida, En-Yuan Shang, C. Shu +10 more
2019EMBO Molecular Medicine48 citations Open access
Semantic Scholar
MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma
Yiru Zhang, T. Nguyen, En-Yuan Shang, Angeliki Mela +14 more
2019Cancer Research41 citations Open access
Semantic Scholar
Isolation and characterization of the TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder
T. McGarvey, T. Nguyen, John E. Tomaszewski, F. Monson +1 more
2001Oncogene40 citations
Semantic Scholar
TERE1, a novel gene affecting growth regulation in prostate carcinoma
T. McGarvey, T. Nguyen, Raghunath Puthiyaveettil, J. Tomaszewski +1 more
2003The Prostate37 citations
Semantic Scholar
Inhibition of HDAC1/2 Along with TRAP1 Causes Synthetic Lethality in Glioblastoma Model Systems
T. Nguyen, Yiru Zhang, En-Yuan Shang, C. Shu +4 more
2020Cells36 citations Open access
Semantic Scholar
Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents
Qing Zhou, Xiotian Sun, Nicolas Pasquier, P. Jefferson +4 more
2021Cancers33 citations Open access
Semantic Scholar
Induction of Synthetic Lethality by Activation of Mitochondrial ClpP and Inhibition of HDAC1/2 in Glioblastoma
T. Nguyen, En-Yuan Shang, Salveena Schiffgens, Consuelo Torrini +7 more
2022Clinical Cancer Research30 citations Open access
Semantic Scholar
Midkine, a newly discovered regulator of the renin-angiotensin pathway in mouse aorta: significance of the pleiotrophin/midkine developmental gene family in angiotensin II signaling.
L. Ezquerra, G. Herradón, T. Nguyen, I. Silos-santiago +1 more
2005Biochemical and Biophysical Research Communications - BBRC30 citations
Semantic Scholar
Pleiotrophin is an important regulator of the renin-angiotensin system in mouse aorta.
G. Herradón, L. Ezquerra, T. Nguyen, T. Vogt +3 more
2004Biochemical and Biophysical Research Communications - BBRC29 citations
Semantic Scholar
Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma
T. Nguyen, En-Yuan Shang, M. Westhoff, G. Karpel-Massler +1 more
2022Cells26 citations Open access
Semantic Scholar
Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma
En-Yuan Shang, T. Nguyen, C. Shu, M. Westhoff +2 more
2020Cancers26 citations Open access
Semantic Scholar
Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors
T. Nguyen, C. Ishida, En-Yuan Shang, C. Shu +3 more
2019Cancers24 citations Open access
Semantic Scholar
Pleiotrophin is a major regulator of the catecholamine biosynthesis pathway in mouse aorta.
L. Ezquerra, G. Herradón, T. Nguyen, T. Vogt +3 more
2004Biochemical and Biophysical Research Communications - BBRC24 citations
Semantic Scholar
Involvement of Bcl-xL in Neuronal Function and Development
Julie Bas, T. Nguyen, G. Gillet
2021International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells.
Zoey Tay, S. Koo, T. Nguyen, Tsu-Soo Tan +7 more
2013Current Medicinal Chemistry13 citations
Semantic Scholar
Drosophila Claspin is required for the G2 arrest that is induced by DNA replication stress but not by DNA double-strand breaks.
Eun-Mi Lee, T. Trinh, H. Shim, Suk-Young Park +3 more
2012DNA Repair13 citations
Semantic Scholar
Inducible expression of Pisum sativum xyloglucan fucosyltransferase in the pea root cap meristem, and effects of antisense mRNA expression on root cap cell wall structural integrity
Fu-Shi Wen, R. Celoy, T. Nguyen, W. Zeng +4 more
2008Plant Cell Reports13 citations Open access
Semantic Scholar
Midkine is a potent regulator of the catecholamine biosynthesis pathway in mouse aorta.
L. Ezquerra, G. Herradón, T. Nguyen, I. Silos-santiago +1 more
2006Life Science9 citations
Semantic Scholar
RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells
E. Bianchetti, S. Bates, T. Nguyen, M. Siegelin +1 more
2021Cells6 citations Open access
Semantic Scholar
Targeting super-enhancers reprograms glioblastoma central carbon metabolism
T. Nguyen, M. Westhoff, G. Karpel-Massler, M. Siegelin
2021OncoTarget5 citations Open access
Semantic Scholar
Pleiotropy of Bcl-2 family proteins is an ancient trait in the metazoan evolution
N. Popgeorgiev, L. Jabbour, T. Nguyen, Nikola Ralchev +6 more
2019bioRxiv5 citations Open access
Semantic Scholar
Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation
T. Nguyen, R. Gadet, Marine Lanfranchi, Romane A Lahaye +9 more
2023iScience4 citations Open access
Semantic Scholar
Methodological Approaches for Assessing Metabolomic Changes in Glioblastomas.
T. Nguyen, En-Yuan Shang, M. Westhoff, G. Karpel-Massler +1 more
2022Methods in molecular biology3 citations
Semantic Scholar
The Endoplasmic Reticulum pool of Bcl-xL dampens the Unfolded Protein Response through IP3R-dependent Calcium Release
L. Jabbour, T. Nguyen, R. Gadet, Olivier D. Lohez +8 more
2021bioRxiv3 citations Open access
Semantic Scholar
Rapid screening for Neurospora crassa strains lacking CuZn superoxide dismutase (sod-1)
D. Natvig, T. Nguyen
19933 citations Open access
Semantic Scholar
TMET-39. INHIBITION OF THE TCA-CYCLE IS SYNTHETICALLY LETHAL WITH LOSS OF FUNCTION OF BCL-XL IN GLIOBLASTOMA
T. Nguyen, En-Yuan Shang, Consuelo Torrini, C. Shu +3 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
EPCO-16. LACTIC ACID IS AN EPIGENETIC METABOLITE THAT DRIVES GLIOBLASTOMA SURVIVAL AND GROWTH
Consuelo Torrini, T. Nguyen, Shuo-Yu Chang, Angeliki Mela +6 more
20201 citations Open access
Semantic Scholar
SIRT 7 promotes genome integrity by regulating non-homologous end joining DNA repair
B. Vazquez, Joshua K. Thackray, Nicolás G. Simonet, Noriko Kane-Goldsmith +6 more
20161 citations
Semantic Scholar
TMET-38. LOSS OF FUNCTION OF CDK7 IS SYNTHETICALLY LETHAL WITH FATTY ACID OXIDATION INHIBITION IN GLIOBLASTOMA
T. Nguyen, En-Yuan Shang, C. Shu, H. Akman +6 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
ETMM-05. LACTIC ACID FACILITATES GLIOBLASTOMA GROWTH THROUGH MODULATION OF THE EPIGENOME
Consuelo Torrini, T. Nguyen, C. Shu, Angeliki Mela +6 more
2021Neuro-Oncology Advances0 citations Open access
Semantic Scholar
ETMM-04. AURKA INHIBITION REPROGRAMS METABOLISM AND IS SYNTHETICALLY LETHAL WITH FATTY ACID OXIDATION INHIBITION IN GLIOBLASTOMA MODEL SYSTEMS
T. Nguyen, C. Shu, En-Yuan Shang, Angeliki Mela +10 more
2021Neuro-Oncology Advances0 citations Open access
Semantic Scholar
TAMI-70. METABOLIC VULNERABILITY TO GPX4 INHIBITION AND FERROPTOSIS OF QUIESCENT ASTROCYTE-LIKE GLIOMA CELL POPULATIONS
M. Banu, A. Dovas, Michael G. Argenziano, Wen-Ting Zhao +11 more
2021Neuro-Oncology0 citations Open access
Semantic Scholar
Heterologous expression of human KGF/FGF7 (Keratinocyte growth factor) in Pichia pastoris
Thư Anh Nguyễn Phạm, T. Nguyen, N. Nguyễn, Thao Thi Phuong Dang
20200 citations Open access
Semantic Scholar
TAMI-33. AURKA INHIBITION REPROGRAMS METABOLISM AND IS SYNTHETICALLY LETHAL WITH FATTY ACID OXIDATION INHIBITION IN GLIOBLASTOMA
T. Nguyen, En-Yuan Shang, C. Shu, Angeliki Mela +8 more
20200 citations Open access
Semantic Scholar
EXTH-50. ACTIVATION OF THE MITOCHONDRIAL CLPP PROTEASE IS SYNTHETICALLY LETHAL WITH HDAC1/2 INHIBITION IN GLIOBLASTOMA MODEL SYSTEMS
Salveena Schiffgens, T. Nguyen, Shuo-Yu Chang, B. Elena +3 more
20200 citations Open access
Semantic Scholar
CBMT-15. MET INHIBITION DRIVES PGC1A DEPENDENT METABOLIC REPROGRAMMING AND ELICITS UNIQUE METABOLIC VULNERABILITIES IN GLIOBLASTOMA
Yiru Zhang, T. Nguyen, Junfei Zhao, En-Yuan Shang +4 more
2019Neuro-Oncology0 citations Open access
Semantic Scholar
Development of Monoclonal Antibodies Specific to Galectin of Pine Wood Nematode, Bursaphelenchus xylophilus (Steiner and Buhrer) Nickle and Their Utilization for Detection of Pine Wood Nematodes
A. Kim, Young Ha Kim, Bo-Hey Choi, T. Nguyen +4 more
20180 citations
Semantic Scholar

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