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A. Alexandrou · SciRah

Researcher profile · Semantic Scholar

A. Alexandrou

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A. Alexandrou — researcher profile on SciRah

h-index: 6
Works: 8
Citations: 644

Most-cited papers

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia
Li-Shuang Cao, Aoibhinn McDonnell, A. Nitzsche, A. Alexandrou +17 more
2016Science Translational Medicine183 citations Open access
Semantic Scholar
Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release
A. Alexandrou, Adam R. Brown, Mark L. Chapman, M. Estacion +24 more
2016PLoS ONE176 citations Open access
Semantic Scholar
Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin
A. Alexandrou, R. S. Duncan, A. Sullivan, J. Hancox +3 more
2006British Journal of Pharmacology113 citations Open access
Semantic Scholar
A novel selective and orally bioavailable Nav1.8 channel blocker, PF‐01247324, attenuates nociception and sensory neuron excitability
C. E. Payne, Adam R. Brown, Jonathon W. Theile, A. Loucif +20 more
2015British Journal of Pharmacology106 citations Open access
Semantic Scholar
An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.
L. T. Cho, A. Alexandrou, R. Torella, J. Knafels +12 more
2018Structure36 citations Open access
Semantic Scholar
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.
R. Storer, A. Pike, N. Swain, A. Alexandrou +20 more
2017Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
The human ether-a'-go-go related gene (hERG) K+ channel blockade by the investigative selective-serotonin reuptake inhibitor CONA-437: limited dependence on S6 aromatic residues.
A. Alexandrou, J. Milnes, Sunny Z. Sun, B. Fermini +6 more
2014Journal of Physiology and Pharmacology5 citations
Semantic Scholar
The impact of voltage-clamp protocol on the apparent potency of a rapidly acting human ether-a-go-go related gene (hERG) potassium channel blocker
A. Alexandrou, J. Hancox, J. Leaney, D. Leishman +1 more
20051 citations
Semantic Scholar

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