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J. Malčíková · SciRah

Researcher profile · Semantic Scholar

J. Malčíková

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J. Malčíková — researcher profile on SciRah

h-index: 23
Works: 192
Citations: 2,565

Most-cited papers

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretation
J. Malčíková, E. Tausch, D. Rossi, L. Sutton +14 more
2018Leukemia190 citations Open access
Semantic Scholar
Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia
J. Malčíková, Kateřina Stano-Kozubík, B. Tichy, B. Kantorová +14 more
2014Leukemia155 citations Open access
Semantic Scholar
Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: A systematic reappraisal of classic cytogenetic data
P. Baliakas, M. Iskas, A. Gardiner, Z. Davis +14 more
2014American journal of hematology/oncology128 citations Open access
Semantic Scholar
The impact of SF3B1 mutations in CLL on the DNA-damage response
G. D. Te Raa, I. Derks, V. Navrkalova, A. Skowrońska +16 more
2014Leukemia94 citations Open access
Semantic Scholar
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors
L. Sutton, E. Young, P. Baliakas, A. Hadzidimitriou +31 more
2016Haematologica76 citations Open access
Semantic Scholar
Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status
B. Kubešová, Š. Pavlová, J. Malčíková, J. Kabáthová +16 more
2017Leukemia74 citations Open access
Semantic Scholar
Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting
L. Sutton, V. Ljungström, L. Mansouri, E. Young +13 more
2015Haematologica71 citations Open access
Semantic Scholar
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options
J. Malčíková, Š. Pavlová, Barbara Kunt Vonkova, L. Radová +15 more
2021Blood55 citations Open access
Semantic Scholar
Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones
K. Plevová, H. Francová, K. Burčková, Y. Brychtova +6 more
2014Haematologica50 citations Open access
Semantic Scholar
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—2024 update
J. Malčíková, Š. Pavlová, Panagotis Baliakas, T. Chatzikonstantinou +14 more
2024Leukemia37 citations Open access
Semantic Scholar
Seshat: A Web service for accurate annotation, validation, and analysis of TP53 variants generated by conventional and next‐generation sequencing
Tuomas Tikkanen, B. Leroy, Jean Louis Fournier, R. Risques +2 more
2018Human Mutation34 citations Open access
Semantic Scholar
TP53 Mutation Analysis in Clinical Practice: Lessons From Chronic Lymphocytic Leukemia
J. Malčíková, Š. Pavlová, K. S. Kozubík, Š. Pospíšilová
2014Human Mutation33 citations Open access
Semantic Scholar
ATM and TP53 mutations show mutual exclusivity but distinct clinical impact in mantle cell lymphoma patients
A. Mareckova, J. Malčíková, N. Tom, K. Pal +8 more
2019Leukemia and Lymphoma32 citations
Semantic Scholar
Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons
A. Rodríguez-Vicente, V. Bikos, M. Hernández-Sánchez, J. Malčíková +2 more
2017OncoTarget31 citations Open access
Semantic Scholar
Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL
K. Brázdilová, K. Plevová, H. Francová, H. Kockova +10 more
2017Leukemia23 citations Open access
Semantic Scholar
Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?
Š. Pospíšilová, L. Sutton, J. Malčíková, E. Tausch +7 more
2016Haematologica23 citations Open access
Semantic Scholar
Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study
M. Doubek, Y. Brychtova, A. Panovská, Ludmila Šebejová +18 more
2015American journal of hematology/oncology21 citations Open access
Semantic Scholar
The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors
J. Malčíková, E. Stalika, Z. Davis, K. Plevová +19 more
2014British Journal of Haematology21 citations Open access
Semantic Scholar
TP53 aberrations in chronic lymphocytic leukemia.
M. Trbušek, J. Malčíková
2013Advances in Experimental Medicine and Biology21 citations
Semantic Scholar
Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia
G. D. T. Raa, J. Malčíková, Š. Pospíšilová, M. Trbušek +12 more
2013Leukemia and Lymphoma21 citations
Semantic Scholar
Complex analysis of the p53 tumor suppressor in lung carcinoma.
J. Šmardová, K. Lišková, B. Ravčuková, J. Malčíková +9 more
2016Oncology Report18 citations Open access
Semantic Scholar
Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
L. Sutton, V. Ljungström, A. Enjuanes, D. Cortese +19 more
2020Haematologica12 citations Open access
Semantic Scholar
TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods
B. Kantorová, J. Malčíková, J. Šmardová, Š. Pavlová +13 more
2015Tumor Biology12 citations
Semantic Scholar
Complex analysis of the TP53 tumor suppressor in mantle cell and diffuse large B-cell lymphomas.
L. Zlámalíková, M. Moulis, B. Ravčuková, K. Lišková +7 more
2017Oncology Report11 citations Open access
Semantic Scholar
Distinct in vitro sensitivity of p53-mutated and ATM-mutated chronic lymphocytic leukemia cells to ofatumumab and rituximab.
Ludmila Šebejová, M. Borsky, Zuzana Jašková, D. Potěšil +8 more
2014Experimental Hematology11 citations Open access
Semantic Scholar
GLASS: assisted and standardized assessment of gene variations from Sanger sequence trace data
K. Pal, V. Bystrý, T. Reigl, M. Demko +9 more
2016bioRxiv10 citations Open access
Semantic Scholar
PRIMA-1MET cytotoxic effect correlates with p53 protein reduction in TP53-mutated chronic lymphocytic leukemia cells.
Zuzana Jašková, Š. Pavlová, J. Malčíková, Y. Brychtova +1 more
2019Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis7 citations
Semantic Scholar
Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC‐wide approach
G. D. T. Raa, J. Malčíková, M. Mraz, M. Trbušek +13 more
2014British Journal of Haematology7 citations Open access
Semantic Scholar
Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL
Š. Pavlová, J. Malčíková, Lenka Radova, Silvia Bonfiglio +95 more
2025HemaSphere6 citations Open access
Semantic Scholar
Transcription Factor YY1 Can Control AID-mediated Mutagenesis
Kristína Zápražná, Arindam Basu, N. Tom, V. Jha +6 more
2017European Journal of Immunology6 citations Open access
Semantic Scholar
Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients
B. Kantorová, J. Malčíková, K. Brázdilová, M. Borsky +12 more
2017British Journal of Haematology6 citations Open access
Semantic Scholar
Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing
T. Kurucova, Kamila Reblova, P. Janovska, J. Porc +9 more
2024Molecular Oncology4 citations Open access
Semantic Scholar
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Helena Olbertová, K. Plevová, Š. Pavlová, J. Malčíková +13 more
2022BMC Cancer4 citations Open access
Semantic Scholar
Opinion: What defines high-risk CLL in the post-chemoimmunotherapy era?
J. Edelmann, J. Malčíková, J. Riches
2023Frontiers in Oncology3 citations Open access
Semantic Scholar
Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage
V. Mančíková, M. Pešová, Š. Pavlová, R. Helma +7 more
2022Molecular Oncology3 citations Open access
Semantic Scholar
Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia
Kristína Zápražná, K. Réblová, V. Svobodová, L. Radová +13 more
2018Annals of Hematology2 citations Open access
Semantic Scholar
Differential Distribution Of Recurrent Gene Mutations In Subsets Of Chronic Lymphocytic Leukemia Patients With Stereotyped B-Cell Receptors: Results From A Multicenter Project Of The European Research Initiative On CLL In A Series Of 2482 Cases
P. Baliakas, A. Hadzidimitriou, L. Sutton, D. Rossi +25 more
20132 citations
Semantic Scholar
Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment‐naïve CLL patients
V. Navrkalova, K. Plevová, Lenka Radova, J. Porc +7 more
2023British Journal of Haematology1 citations Open access
Semantic Scholar
Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL
Š. Pavlová, J. Malčíková, Lenka Radova, Silvia Bonfiglio +94 more
2023Blood1 citations Open access
Semantic Scholar
Editorial: Biology and treatment of high-risk CLL
E. Tausch, J. Malčíková, J. Riches, J. Edelmann
2023Frontiers in Oncology1 citations Open access
Semantic Scholar
ToTem: a tool for variant calling pipeline optimization
N. Tom, Ondrej Tom, J. Malčíková, Š. Pavlová +6 more
2018BMC Bioinformatics1 citations Open access
Semantic Scholar
SF3B1 mutations in CLL are associated with a defective DNAdamage response
E. Eldering, D. T. Raa, I. Derks, V. Navrkalova +12 more
20141 citations
Semantic Scholar
Abstract 5198: Identification of microRNAs involved in DNA damage response in malignant B cells and their biological and clinical relevance
K. Černá, J. Oppelt, L. Radová, K. Musilová +13 more
20141 citations
Semantic Scholar
Longitudinal single-cell analysis reveals dynamic clonal competition and convergent evolution shaped by therapy sequencing in a young patient with chronic lymphocytic leukemia.
A. Panovská, Tomáš Arpáš, Adéla Prchlíková, Š. Pavlová +8 more
2026Haematologica0 citations Open access
Semantic Scholar
In-frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL.
Š. Pavlová, Johana Gombíková, Silvia Petrezsélyová, L. Macůrek +25 more
2026Journal of Pathology0 citations Open access
Semantic Scholar
182eP TP53 clonal hematopoiesis during PARP inhibitor therapy in ovarian cancer: Association with therapy-related myeloid neoplasms
L. Ehrlichová, M. Bednaříková, Š. Pavlová, E. Zapletalova +7 more
2026ESMO Open0 citations Open access
Semantic Scholar
Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)
J. Mihályová, A. Panovská, M. Šimkovič, P. Turcsányi +21 more
2023Blood0 citations Open access
Semantic Scholar
How to clinically interpret the results of TP53 analyses in chronic lymphocytic leukaemia in the context of available therapeutic regimens
Barbara Kunt Vonková, Š. Pavlová, J. Malčíková, K. Pal +4 more
2023Transfuze a hematologie dnes0 citations Open access
Semantic Scholar
P602: SINGLE-CELL RNA-SEQUENCING ENABLES TRACKING AND CHARACTERIZATION OF RARE CLL CELLS WITH THE POTENTIAL TO CAUSE REFRACTORINESS.
T. Kurucova, K. Réblová, Martina Vališová, Jakub Paweł Porc +8 more
2023HemaSphere0 citations Open access
Semantic Scholar
P614: SUBCLONAL ARCHITECTURE OF CHROMOSOMES REVEALED BY SINGLE-CELL ANALYSIS OF GENE EXPRESSION IN A PATIENT WITH CLONAL EVOLUTION OF RELAPSING/REFRACTORY CLL
J. Kotaskova, T. Kurucova, K. Réblová, M. Vališová +10 more
2022HemaSphere0 citations Open access
Semantic Scholar

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