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Yun-Ping Zhou · SciRah

Researcher profile · Semantic Scholar

Yun-Ping Zhou

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Yun-Ping Zhou — researcher profile on SciRah

h-index: 27
Works: 42
Citations: 4,408

Most-cited papers

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
Yun-Ping Zhou, V. Grill
1994Journal of Clinical Investigation729 citations Open access
Semantic Scholar
Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component.
A. Attele, Yun-Ping Zhou, Jing-Tian Xie, Ji-an Wu +6 more
2002Diabetes638 citations
Semantic Scholar
Chronic Inhibition of Dipeptidyl Peptidase-4 With a Sitagliptin Analog Preserves Pancreatic β-Cell Mass and Function in a Rodent Model of Type 2 Diabetes
J. Mu, J. Woods, Yun-Ping Zhou, R. S. Roy +9 more
2006Diabetes473 citations Open access
Semantic Scholar
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.
Yun-Ping Zhou, V. Grill
1995Journal of Clinical Endocrinology and Metabolism316 citations
Semantic Scholar
Calpains play a role in insulin secretion and action.
S. Sreenan, Yun-Ping Zhou, K. Otani, P. Hansen +12 more
2001Diabetes185 citations Open access
Semantic Scholar
Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice
Carina P. Tan, Yue Feng, Yun-Ping Zhou, G. Eiermann +14 more
2008Diabetes168 citations Open access
Semantic Scholar
Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion.
J. Herrington, Yun-Ping Zhou, R. Bugianesi, P. Dulski +17 more
2006Diabetes166 citations Open access
Semantic Scholar
Defective Pancreatic β-Cell Glycolytic Signaling in Hepatocyte Nuclear Factor-1α-deficient Mice*
I. Dukes, S. Sreenan, M. Roe, M. Levisetti +7 more
1998Journal of Biological Chemistry163 citations Open access
Semantic Scholar
Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice
Enpeng Zhao, Mark P. Keller, M. Rabaglia, A. Oler +22 more
2009Mammalian Genome151 citations Open access
Semantic Scholar
Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes.
J. Mu, Aleksandr Petrov, G. Eiermann, J. Woods +10 more
2009European Journal of Pharmacology140 citations
Semantic Scholar
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.
Yun-Ping Zhou, J. Pena, M. Roe, Anshu A. Mittal +10 more
2000American Journal of Physiology. Endocrinology and Metabolism113 citations
Semantic Scholar
A Fatty Acid—Induced Decrease in Pyruvate Dehydrogenase Activity Is an Important Determinant of β-Cell Dysfunction in the Obese Diabetic db/db Mouse
Yun-Ping Zhou, P. Berggren, V. Grill
1996Diabetes101 citations
Semantic Scholar
Palmitate-Induced β-Cell Insensitivity to Glucose is Coupled to Decreased Pyruvate Dehydrogenase Activity and Enhanced Kinase Activity in Rat Pancreatic Islets
Yun-Ping Zhou, V. Grill
1995Diabetes87 citations
Semantic Scholar
Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets*
Sarah M. Ronnebaum, M. Jensen, Hans E. Hohmeier, Shawn C. Burgess +9 more
2008Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets.
D. Waddleton, Wei-Zhen Wu, Yue Feng, C. Thompson +6 more
2008Biochemical Pharmacology80 citations
Semantic Scholar
Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets
Z. Tu, Mark P. Keller, Chun-Sheng Zhang, M. Rabaglia +13 more
2012PLoS Genetics75 citations Open access
Semantic Scholar
The Role of Voltage-Gated Potassium Channels Kv2.1 and Kv2.2 in the Regulation of Insulin and Somatostatin Release from Pancreatic Islets
X. Li, J. Herrington, Aleksandr Petrov, Lan Ge +12 more
2013Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
Overexpression of Repressive cAMP Response Element Modulators in High Glucose and Fatty Acid-treated Rat Islets
Yun-Ping Zhou, Kimberly Marlen, J. Palma, A. Schweitzer +5 more
2003Journal of Biological Chemistry65 citations Open access
Semantic Scholar
A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
Yun-Ping Zhou, S. Sreenan, Chien-Yuan Pan, K. Currie +11 more
2003Metabolism: Clinical and Experimental63 citations Open access
Semantic Scholar
Bombesin receptor subtype-3 (BRS-3) regulates glucose-stimulated insulin secretion in pancreatic islets across multiple species.
Yue Feng, Xiao-Ming Guan, Jing Li, Joseph M. Metzger +6 more
2011Endocrinology60 citations
Semantic Scholar
Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists.
Changyou Zhou, Cheng Tang, E. Chang, M. Ge +18 more
2010Bioorganic & Medicinal Chemistry Letters55 citations Open access
Semantic Scholar
Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.
Jin Shang, Jing Li, Mark P. Keller, H. Hohmeier +11 more
2015Molecular Endocrinology54 citations Open access
Semantic Scholar
The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
O. Rudenko, Jin Shang, Alexander Munk, Jeppe P. Ekberg +16 more
2018Molecular Metabolism51 citations Open access
Semantic Scholar
Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion
Mufaddal S. Soni, M. Rabaglia, Sushant Bhatnagar, Jin Shang +8 more
2014Diabetes49 citations Open access
Semantic Scholar
Identification of Glucose-Dependent Insulin Secretion Targets in Pancreatic β Cells by Combining Defined-Mechanism Compound Library Screening and siRNA Gene Silencing
Wei-Zhen Wu, Jin Shang, Yue Feng, C. Thompson +8 more
2008Journal of biomolecular screening38 citations Open access
Semantic Scholar
Matrix metalloproteinases contribute to insulin insufficiency in Zucker diabetic fatty rats.
Yun-Ping Zhou, Azadeh Madjidi, Maria E. Wilson, David A Nothhelfer +6 more
2005Diabetes38 citations Open access
Semantic Scholar
Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat
Mayumi Futamura, Jun Yao, X. Li, R. Bergeron +11 more
2012Diabetologia37 citations
Semantic Scholar
FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Cι/λ.
Ling Kong, W. Feng, M. Wright, Yuli Chen +3 more
2013European Journal of Pharmacology26 citations
Semantic Scholar
A small-molecule glucokinase activator lowers blood glucose in the sulfonylurea-desensitized rat.
Sumika Ohyama, Hiroki Takano, T. Iino, Teruyuki Nishimura +4 more
2010European Journal of Pharmacology21 citations
Semantic Scholar
Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition.
Weiguo Liu, P. Shao, Gui-Bai Liang, John A. Bawiec +16 more
2018ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes
Shrenik K. Shah, Shu-Wen He, Liangqin Guo, Quang T. Truong +40 more
2015ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes.
Shu-Wen He, Zhi-Xiong Ye, Quang T. Truong, Shrenik K. Shah +38 more
2012ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Evaluation of Neural Tube Defects (NTDs) After Exposure to Raltegravir During Pregnancy
H. Shamsuddin, Casey L. Raudenbush, Brittany L. Sciba, Yun-Ping Zhou +5 more
2019Journal of Acquired Immune Deficiency Syndromes14 citations Open access
Semantic Scholar
Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.
A. Pasternak, Zhe Feng, R. D. de Jesus, Zhi-Xiong Ye +17 more
2012ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists.
Shu-Wen He, Zhong Lai, Zhi-Xiong Ye, Peter H. Dobbelaar +35 more
2014ACS Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Hepatic safety of the antifungal triazole agent posaconazole: characterization of adverse event reports in a manufacturer’s safety database
R. O'Flynn, Yun-Ping Zhou, H. Waskin, Ronald W Leong +1 more
2022Expert Opinion on Drug Safety7 citations
Semantic Scholar
SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists.
Shu-Wen He, Peter H. Dobbelaar, Liangqin Guo, Zhi-Xiong Ye +38 more
2016Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Silybin decreases erythrocytic sorbitol level and improves peripheral nerve conduction velocity in patients with non-insulin dependent diabetes mellitus
Jia-Qing Zhang, Xiao-Ming Mao, Yun-Ping Zhou
19956 citations
Semantic Scholar
Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists.
De-Run Li, Zhicai Wu, Yang Yu, R. Ball +19 more
2014ACS Medicinal Chemistry Letters4 citations Open access
Semantic Scholar
Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists.
Zhong Lai, Shu-Wen He, Edward C. Sherer, Zhicai Wu +14 more
2015Bioorganic & Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
702. Hepatic Safety Among Patients Treated with Anti-Fungal Triazole Agent Posaconazole: Characterization of Adverse events in a Manufacturer’s Safety Database
Yun-Ping Zhou, R. O'Flynn, H. Waskin, Ronald W Leong +1 more
2019Open Forum Infectious Diseases0 citations Open access
Semantic Scholar
Silybin decreases erythrocytic sorbitol level and improves peripheral nerve conduction velocity in patients with non-insulin dependent diabetes mellitus
Jia-Qing Zhang, Xiao-Ming Mao, Yun-Ping Zhou
1995Chinese journal of integrated traditional and Western medicine0 citations
Semantic Scholar

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