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W. Clark · SciRah

Researcher profile · Semantic Scholar

W. Clark

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W. Clark — researcher profile on SciRah

h-index: 15
Works: 25
Citations: 2,347

Most-cited papers

A large-scale evaluation of computational protein function prediction
P. Radivojac, W. Clark, Tal Ronnen-Oron, A. Schnoes +98 more
2013Nature Methods1,026 citations Open access
Semantic Scholar
The Aquila Digital Community The Aquila Digital Community
Tal Yuxiang Jiang, Ronnen Oron, W. Clark, Asma R. Bankapur +144 more
246 citations
Semantic Scholar
Testing the Ortholog Conjecture with Comparative Functional Genomic Data from Mammals
Nathan L. Nehrt, W. Clark, P. Radivojac, M. Hahn
2011PLoS Comput. Biol.209 citations Open access
Semantic Scholar
AN INTEGRATED APPROACH TO INFERRING GENE-DISEASE ASSOCIATIONS IN HUMANS
P. Radivojac, Kang Peng, W. Clark, Brandon Peters +3 more
2008Proteins: Structure, Function, and Bioinformatics190 citations Open access
Semantic Scholar
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Yuxiang Jiang, T. Oron, W. Clark, Asma R. Bankapur +143 more
2016Genome Biology155 citations Open access
Semantic Scholar
Analysis of protein function and its prediction from amino acid sequence
W. Clark, P. Radivojac
2011Proteins: Structure, Function, and Bioinformatics148 citations
Semantic Scholar
Information-theoretic evaluation of predicted ontological annotations
W. Clark, P. Radivojac
2013Bioinform.137 citations Open access
Semantic Scholar
The impact of incomplete knowledge on the evaluation of protein function prediction: a structured-output learning perspective
Yuxiang Jiang, W. Clark, I. Friedberg, P. Radivojac
2014Bioinform.49 citations Open access
Semantic Scholar
Characterization of glycan substrates accumulating in GM1 Gangliosidosis
R. Lawrence, Jeremy Van Vleet, Linley Mangini, Adam Harris +8 more
2019Molecular Genetics and Metabolism Reports33 citations Open access
Semantic Scholar
Using Compression to Identify Classes of Inauthentic Texts
Mehmet M. Dalkilic, W. Clark, J. Costello, P. Radivojac
2006SDM32 citations
Semantic Scholar
Prediction of functional regulatory SNPs in monogenic and complex disease
Yi-Qiang Zhao, W. Clark, M. Mort, David N. Cooper +2 more
2011Human Mutation26 citations Open access
Semantic Scholar
Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix
Marena I. Trinidad, Xinying Hong, Steven Froelich, Jessica Daiker +8 more
2023Genome Biology20 citations Open access
Semantic Scholar
Identifying therapeutic drug targets using bidirectional effect genes
K. Estrada, Steven Froelich, Arthur Wuster, C. Bauer +11 more
2021Nature Communications20 citations Open access
Semantic Scholar
Assessment of predicted enzymatic activity of alpha-N-acetylglucosaminidase (NAGLU) variants of unknown significance for CAGI 2016
W. Clark, Laura Kasak, C. Bakolitsa, Zhi-Qiang Hu +29 more
2019Human Mutation19 citations Open access
Semantic Scholar
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence
W. Clark, G. Yu, M. Aoyagi-Scharber, Jonathan H. LeBowitz
2018bioRxiv15 citations Open access
Semantic Scholar
From protein-disease associations to disease informatics.
Mehmet M. Dalkilic, J. Costello, W. Clark, P. Radivojac
2008Frontiers in Bioscience11 citations Open access
Semantic Scholar
Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A
Shantanu Jain, Marena I. Trinidad, Thanh-Binh Nguyen, Kaiya Jones +65 more
2025Human Genetics4 citations Open access
Semantic Scholar
Vector Quantization Kernels for the Classification of Protein Sequences and Structures
W. Clark, P. Radivojac
2013Pacific Symposium on Biocomputing4 citations
Semantic Scholar
Identifying therapeutic drug targets for rare and common forms of short stature
K. Estrada, Steven Froelich, Arthur Wuster, C. Bauer +11 more
2020bioRxiv3 citations Open access
Semantic Scholar
Utilizing activity assays and population-wide allele frequencies to assess the contribution of novel mutations in NAGLU to MPS IIIB incidence
J. Lebowitz, W. Clark, G. Yu, M. Aoyagi-Scharber
20161 citations
Semantic Scholar
Information-Theoretic Evaluation for Computational Biomedical Ontologies
W. Clark
2014SpringerBriefs in Computer Science1 citations
Semantic Scholar
Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A
Shantanu Jain, Marena I. Trinidad, Thanh-Binh Nguyen, Kaiya Jones +65 more
2024bioRxiv0 citations Open access
Semantic Scholar
Experiments and Results
W. Clark
20140 citations
Semantic Scholar
Understanding protein function through statistical inference and evolutionary analysis
W. Clark
20130 citations
Semantic Scholar
Predicting Protein-Disease Relationships Using Sequence, Physicochemical Properties, and Molecular Function Information
P. Radivojac, Kang Peng, W. Clark, Brandon Peters +3 more
20080 citations Open access
Semantic Scholar

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