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P. Reinemer · SciRah

Researcher profile · Semantic Scholar

P. Reinemer

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P. Reinemer — researcher profile on SciRah

h-index: 27
Works: 61
Citations: 4,984

Most-cited papers

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases
W. Stöcker, F. Grams, P. Reinemer, W. Bode +3 more
1995Protein Science683 citations Open access
Semantic Scholar
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor.
S. Roehrig, A. Straub, J. Pohlmann, T. Lampe +4 more
2005Journal of Medicinal Chemistry442 citations Open access
Semantic Scholar
X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function.
H. Dirr, P. Reinemer, R. Huber
1994European Journal of Biochemistry394 citations
Semantic Scholar
Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate.
M. Egloff, Patricia T. W. Cohen, P. Reinemer, David Barford
1995Journal of Molecular Biology384 citations
Semantic Scholar
Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.
I. Sinning, G. Kleywegt, S. Cowan, P. Reinemer +9 more
1993Journal of Molecular Biology361 citations
Semantic Scholar
Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer.
S. Steinbacher, R. Seckler, S. Miller, Boris Steipe +2 more
1994Science312 citations
Semantic Scholar
The X‐ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.
W. Bode, P. Reinemer, R. Huber, T. Kleine +2 more
1994EMBO Journal290 citations Open access
Semantic Scholar
The three‐dimensional structure of class pi glutathione S‐transferase in complex with glutathione sulfonate at 2.3 A resolution.
P. Reinemer, H. W. Dirr, R. Ladenstein, J. Schäffer +2 more
1991EMBO Journal282 citations Open access
Semantic Scholar
Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution.
P. Reinemer, Heini W. Dirr, R. Ladenstein, R. Huber +3 more
1992Journal of Molecular Biology219 citations
Semantic Scholar
Crystal Structure of the Interleukin-4/Receptor α Chain Complex Reveals a Mosaic Binding Interface
T. Hage, W. Sebald, P. Reinemer
1999206 citations Open access
Semantic Scholar
Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution: structural characterization of herbicide-conjugating plant glutathione S-transferases and a novel active site architecture.
P. Reinemer, L. Prade, P. Hof, T. Neuefeind +7 more
1996Journal of Molecular Biology191 citations
Semantic Scholar
X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
F. Grams, P. Reinemer, James C. Powers, T. Kleine +4 more
1995European Journal of Biochemistry139 citations
Semantic Scholar
Structural implications for the role of the N terminus in the ‘superactivation’ of collagenases
P. Reinemer, F. Grams, R. Huber, T. Kleine +4 more
1994FEBS Letters116 citations Open access
Semantic Scholar
Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.
M. Stadler, J. Bitzer, Anke Mayer-Bartschmid, H. Müller +5 more
2007Journal of Natural Products85 citations Open access
Semantic Scholar
Cloning, sequencing, crystallization and X-ray structure of glutathione S-transferase-III from Zea mays var. mutin: a leading enzyme in detoxification of maize herbicides.
T. Neuefeind, R. Huber, P. Reinemer, J. Knäblein +3 more
1997Journal of Molecular Biology79 citations
Semantic Scholar
The metzincin-superfamily of zinc-peptidases.
W. Bode, F. Grams, P. Reinemer, F. Gomis-Ruth +3 more
1996Advances in Experimental Medicine and Biology79 citations
Semantic Scholar
Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution.
H. Dirr, P. Reinemer, R. Huber
1994Journal of Molecular Biology79 citations
Semantic Scholar
Plant glutathione S-transferases and herbicide detoxification.
T. Neuefeind, P. Reinemer, B. Bieseler
1997Biological chemistry74 citations
Semantic Scholar
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
F. Wagner, M. Weïwer, S. Steinbacher, A. Schomburg +14 more
2016Bioorganic & Medicinal Chemistry72 citations Open access
Semantic Scholar
Class π glutathione S-transferase from pig lung
H. Dirr, K. Mann, R. Huber, R. Ladenstein +1 more
199156 citations
Semantic Scholar
Equilibrium unfolding of class pi glutathione S-transferase.
Heini W. Dirr, P. Reinemer
1991Biochemical and Biophysical Research Communications - BBRC49 citations
Semantic Scholar
Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
G. Hansen, Heike Gielen-Haertwig, P. Reinemer, D. Schomburg +2 more
2011Journal of Molecular Biology45 citations Open access
Semantic Scholar
Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi.
T. Manoharan, Andrew M. Gulick, P. Reinemer, Heini W. Dirr +2 more
1992Journal of Molecular Biology44 citations
Semantic Scholar
Electrostatic evidence for the activation of the glutathione thiol by Tyr7 in pi-class glutathione transferases.
Andrej Karshikoff, P. Reinemer, R. Huber, R. Ladenstein
1993European Journal of Biochemistry43 citations
Semantic Scholar
Mutations that stabilize folding intermediates of phage P22 tailspike protein: folding in vivo and in vitro, stability, and structural context.
M. Beissinger, Sang Chul Lee, S. Steinbacher, P. Reinemer +3 more
1995Journal of Molecular Biology36 citations
Semantic Scholar
X‐ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors
F. Grams, P. Reinemer, James C. Powers, T. Kleine +4 more
199534 citations
Semantic Scholar
Crystal structure of full length topoisomerase I from Thermotoga maritima.
G. Hansen, A. Harrenga, B. Wieland, D. Schomburg +1 more
2006Journal of Molecular Biology33 citations
Semantic Scholar
Chemical modification of GSH transferase P1-1 confirms the presence of Arg-13, Lys-44 and one carboxylate group in the GSH-binding domain of the active site.
Chu-Lin Xia, David J. Meyer, Hui-Li Chen, P. Reinemer +2 more
1993Biochemical Journal23 citations Open access
Semantic Scholar
Macrocyclic Statine‐Based Inhibitors of BACE‐1
A. Barazza, Marion G. Götz, S. A. Cadamuro, P. Goettig +8 more
2007ChemBioChem22 citations
Semantic Scholar
Unusual reactivity of Tyr-7 of GSH transferase P1-1.
David J. Meyer, Chu-Lin Xia, B. Coles, Hui-Li Chen +3 more
1993Biochemical Journal22 citations Open access
Semantic Scholar
A Versatile High-Throughput Screen for Inhibitors of Lipid Kinase Activity: Development of an Immobilized Phospholipid Plate Assay for Phosphoinositide 3-Kinase γ
K. Fuchikami, H. Togame, A. Sagara, Tomoko Satoh +3 more
2002Journal of biomolecular screening21 citations Open access
Semantic Scholar
Targeted proteomics in biomarker validation: Detection and quantification of proteins using a multi‐dimensional peptide separation strategy
D. Immler, Simone Greven, P. Reinemer
2006Proteomics20 citations
Semantic Scholar
Class pi glutathione S-transferase from pig lung. Purification, biochemical characterization, primary structure and crystallization.
Heini W. Dirr, Karlheinz Mann, R. Huber, R. Ladenstein +1 more
1991European Journal of Biochemistry8 citations
Semantic Scholar
INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX
T. Hage, W. Sebald, P. Reinemer
20007 citations
Semantic Scholar
Herbicide detoxification by glutathione S-transferases as implicated from X-ray structures†
A. Zajc, T. Neuefeind, L. Prade, P. Reinemer +2 more
19997 citations
Semantic Scholar
STRUCTURE OF GLUTATHIONE S-TRANSFERASE
P. Reinemer, L. Prade, P. Hof, T. Neuefeind +4 more
19976 citations
Semantic Scholar
Inhibition of Matrix Metalloproteinases in Rheumatoid Arthritis and the Crystallographic Binding Mode of a Peptide Inhibitor
Harald Tschesche, J. Blaser, T. Kleine, S. Schnierer +4 more
1994Annals of the New York Academy of Sciences5 citations
Semantic Scholar
CRYSTAL AND MOLECULAR STRUCTURE OF 1-AMINO-BENZYLPHOSPHONOUS ACID MONOHYDRATE
P. Reinemer, G. Hägele, Dietrich Mootz, R. Tyka
19925 citations
Semantic Scholar
Development of a Simple and Robust Assay to Screen for Inhibitors of Sphingosine Kinases
H. Togame, Reiko Dodo, T. Inaoka, P. Reinemer
2007Assay and drug development technologies4 citations
Semantic Scholar
[22] X-ray structure methods for glutathione binding
P. Reinemer, H. Dirr, R. Huber
19954 citations
Semantic Scholar
MPSA short communications
E. M. Barnes, P. Calkin, S. Kuroda, S. Norioka +195 more
19883 citations
Semantic Scholar
IN SILICO MOLECULAR DOCKING AND ADMET TOXICITY STUDIES OF POLYESTERS CONTAINING OXADIAZOLE MOIETY
C. Subha, B. Pavithra, Frank Harris, M. Lakouraj +21 more
2021International Journal of Biology Pharmacy and Allied Sciences1 citations Open access
Semantic Scholar
Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro
D. Steinritz, Robin Lüling, M. Siegert, H. Mückter +5 more
2021Archives of Toxicology1 citations Open access
Semantic Scholar
COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)
P. Reinemer, F. Grams, R. Huber, T. Kleine +4 more
19961 citations
Semantic Scholar
Function and Structure of Human Leucocyte Collagenase
H. Tschesche, V. Knäuper, T. Kleine, P. Reinemer +3 more
19951 citations
Semantic Scholar
X-ray structure methods for glutathione binding.
P. Reinemer, H. Dirr, R. Huber
1995Methods in Enzymology1 citations
Semantic Scholar
Factor Xa in complex with BAY59-7939
S. Roehrig, A. Straub, J. Pohlmann, T. Lampe +5 more
20080 citations
Semantic Scholar
S-transferase incomplexwithglutathione sulfonate at 2.3A resolution
P. Reinemer, R. Ladenstein, O. Gallay
20050 citations
Semantic Scholar
Development of a simple homogeneous assay to screen for inhibitors of N-acetylglucosamine-6-sulfotransferases.
H. Togame, M. Shimazaki, A. Yamato, Shin-ichi Watanabe +2 more
2003Analytical Biochemistry0 citations
Semantic Scholar
The Interleukin-4-Receptor: From Recognition Mechanism of Pharmacological Target Structure
P. Reinemer, W. Sebald, A. Duschl
20000 citations
Semantic Scholar

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