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R. Jenkins · SciRah

Researcher profile · Semantic Scholar

R. Jenkins

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R. Jenkins — researcher profile on SciRah

h-index: 38
Works: 70
Citations: 8,899

Most-cited papers

Defining T cell states associated with response to checkpoint immunotherapy in melanoma
M. Sade-Feldman, K. Yizhak, Stacey L. Bjorgaard, John P. Ray +31 more
2018Cell1,933 citations Open access
Semantic Scholar
Mechanisms of resistance to immune checkpoint inhibitors
R. Jenkins, D. Barbie, K. Flaherty
2018British Journal of Cancer1,263 citations Open access
Semantic Scholar
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
Livnat Jerby-Arnon, P. Shah, Michael S. Cuoco, C. Rodman +48 more
2018Cell763 citations Open access
Semantic Scholar
CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation
Jiehui Deng, Eric S. Wang, R. Jenkins, Shuai Li +43 more
2017Cancer Discovery619 citations Open access
Semantic Scholar
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
R. Jenkins, A. Aref, Patrick H. Lizotte, E. Ivanova +80 more
2017Cancer Discovery508 citations Open access
Semantic Scholar
Mapping the immune environment in clear cell renal carcinoma by single-cell genomics
Nicholas C. Borcherding, Ajaykumar Vishwakarma, A. Voigt, A. Bellizzi +6 more
2021Communications Biology333 citations Open access
Semantic Scholar
Treatment of Advanced Melanoma in 2020 and Beyond
R. Jenkins, D. Fisher
2020Journal of Investigative Dermatology305 citations Open access
Semantic Scholar
Roles and Regulation of Secretory and Lysosomal Acid Sphingomyelinase
R. Jenkins, D. Canals, Y. Hannun
2009Cellular Signalling282 citations Open access
Semantic Scholar
Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
I. Cañadas, Rohit Thummalapalli, J. W. Kim, S. Kitajima +34 more
2018Nature Medicine275 citations Open access
Semantic Scholar
3D Microfluidic Ex Vivo Culture of Organotypic Tumor Spheroids to Model Immune Checkpoint Blockade
A. Aref, M. Campisi, E. Ivanova, A. Portell +19 more
2018Lab on a Chip191 citations Open access
Semantic Scholar
Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases
D. Canals, David M. Perry, R. Jenkins, Yusuf A. Hannun
2011British Journal of Pharmacology171 citations Open access
Semantic Scholar
Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
Y. Zeidan, R. Jenkins, Y. Hannun
2008Journal of Cell Biology159 citations Open access
Semantic Scholar
Targeting TBK1 to overcome resistance to cancer immunotherapy
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A. Kessler +55 more
2023Nature143 citations Open access
Semantic Scholar
Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism[S]
T. Mullen, Stefka D. Spassieva, R. Jenkins, K. Kitatani +3 more
2011Journal of Lipid Research129 citations Open access
Semantic Scholar
Mechanisms of Resistance to Immune Checkpoint Blockade
David Liu, R. Jenkins, R. Sullivan
2018American Journal of Clinical Dermatology124 citations Open access
Semantic Scholar
Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
Meng-Ju Wu, Lei Shi, J. Dubrot, J. Merritt +29 more
2021Cancer Discovery117 citations Open access
Semantic Scholar
Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death
T. Mullen, R. Jenkins, C. Clarke, J. Bielawski +2 more
2011Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Response to crizotinib in a patient with lung adenocarcinoma harboring a MET splice site mutation
R. Jenkins, G. Oxnard, S. Elkin, E. Sullivan +2 more
2015Clinical Lung Cancer103 citations Open access
Semantic Scholar
Autophagy inhibition dysregulates TBK1 signaling and promotes pancreatic inflammation
Sheng-Hong Yang, Y. Imamura, R. Jenkins, I. Cañadas +15 more
2016Cancer immunology research88 citations Open access
Semantic Scholar
Differential Effects of Ceramide and Sphingosine 1-Phosphate on ERM Phosphorylation
D. Canals, R. Jenkins, P. Roddy, M. Hernandez-Corbacho +2 more
2010Journal of Biological Chemistry76 citations Open access
Semantic Scholar
A novel role for protein kinase Cδ‐mediated phosphorylation of acid sphingomyelinase in UV light‐induced mitochondrial injury
Youssef H. Zeidan, Bill X. Wu, R. Jenkins, L. Obeid +1 more
2008The FASEB Journal74 citations
Semantic Scholar
Defining a role for sphingosine kinase 1 in p53-dependent tumors
Linda A. Heffernan-Stroud, K. Helke, R. Jenkins, A. D. de Costa +2 more
2011Oncogene73 citations Open access
Semantic Scholar
Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy
Y. Zeidan, R. Jenkins, John B. Korman, Xiang Liu +3 more
2008Current Drug Targets72 citations Open access
Semantic Scholar
Regulated Secretion of Acid Sphingomyelinase
R. Jenkins, D. Canals, J. Idkowiak-Baldys, Fabio Simbari +5 more
2010Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Protein Kinase C-induced Activation of a Ceramide/Protein Phosphatase 1 Pathway Leading to Dephosphorylation of p38 MAPK*
K. Kitatani, J. Idkowiak-Baldys, J. Bielawski, Tarek A. Taha +5 more
2006Journal of Biological Chemistry69 citations Open access
Semantic Scholar
A Novel Mechanism of Lysosomal Acid Sphingomyelinase Maturation
R. Jenkins, J. Idkowiak-Baldys, Fabio Simbari, D. Canals +4 more
2010Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.
Kartik Sehgal, A. Portell, E. Ivanova, Patrick H. Lizotte +24 more
2020Journal of Clinical Investigation64 citations Open access
Semantic Scholar
Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease
Ashley J. Snider, Bill X. Wu, R. Jenkins, Jonathan A Sticca +3 more
2012Prostaglandins & other lipid mediators60 citations Open access
Semantic Scholar
Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis.
Hong-Gang Yu, Y. Zeidan, Bill X. Wu, R. Jenkins +3 more
2009American Journal of Respiratory Cell and Molecular Biology60 citations Open access
Semantic Scholar
Acid β-Glucosidase 1 Counteracts p38δ-dependent Induction of Interleukin-6
K. Kitatani, Kely L. Sheldon, V. Anelli, R. Jenkins +4 more
2009Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Assessing Therapeutic Efficacy of MEK Inhibition in a KRASG12C-Driven Mouse Model of Lung Cancers
Shuai Li, Shengwu Liu, Jie-Hui Deng, Esra A. Akbay +23 more
2018Clinical Cancer Research56 citations Open access
Semantic Scholar
Involvement of Acid β-Glucosidase 1 in the Salvage Pathway of Ceramide Formation*
K. Kitatani, Kely L. Sheldon, V. Rajagopalan, V. Anelli +5 more
2009Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low‐density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release
J. Truman, Mohammed M. Al Gadban, Kent J. Smith, R. Jenkins +6 more
2012Immunology48 citations Open access
Semantic Scholar
Accumulation of Long-Chain Glycosphingolipids during Aging Is Prevented by Caloric Restriction
M. Hernandez-Corbacho, R. Jenkins, C. Clarke, Y. Hannun +3 more
2011PLoS ONE45 citations Open access
Semantic Scholar
Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States
J. W. Kim, Omar O. Abudayyeh, Huwate Yeerna, Chen-Hsiang Yeang +32 more
2017Cell Systems44 citations Open access
Semantic Scholar
Molecular and Genomic Determinants of Response to Immune Checkpoint Inhibition in Cancer.
R. Jenkins, Rohit Thummalapalli, Jacob Carter, I. Cañadas +1 more
2018Annual Review of Medicine43 citations Open access
Semantic Scholar
Targeting TANK-binding kinase 1 (TBK1) in cancer
Or-Yam Revach, Shu-Ming Liu, R. Jenkins
2020Expert opinion on therapeutic targets40 citations Open access
Semantic Scholar
Regulation of CC Ligand 5/RANTES by Acid Sphingomyelinase and Acid Ceramidase*
R. Jenkins, C. Clarke, D. Canals, Ashley J. Snider +8 more
2011Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Neutral Sphingomyelinase-2 Mediates Growth Arrest by Retinoic Acid through Modulation of Ribosomal S6 Kinase*
C. Clarke, Krutika N. Mediwala, R. Jenkins, C. A. Sutton +2 more
2011Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Going with the Flow: Modeling the Tumor Microenvironment Using Microfluidic Technology
Hongyan Xie, Jackson W. Appelt, R. Jenkins
2021Cancers30 citations Open access
Semantic Scholar
Safety Study of Adeno-Associated Virus Serotype 2-Mediated Human Acid Sphingomyelinase Expression in the Nonhuman Primate Brain
Ernesto A. Salegio, L. Samaranch, R. Jenkins, C. Clarke +10 more
2012Human Gene Therapy29 citations Open access
Semantic Scholar
Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase
A. Bai, C. Mao, R. Jenkins, Z. Szulc +2 more
2017PLoS ONE28 citations Open access
Semantic Scholar
Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration
Bill X. Wu, Jie Fan, N. Boyer, R. Jenkins +3 more
2015PLoS ONE25 citations Open access
Semantic Scholar
NRAS mutant melanoma: an overview for the clinician for melanoma management.
R. Jenkins, R. Sullivan
2016Melanoma Management19 citations Open access
Semantic Scholar
Translational Studies Using the MALT1 Inhibitor (S)-Mepazine to Induce Treg Fragility and Potentiate Immune Checkpoint Therapy in Cancer
Mauro Di Pilato, Yun Gao, Yi Sun, Amina Fu +11 more
2023Journal of Immunotherapy and Precision Oncology10 citations Open access
Semantic Scholar
Mapping the Immune Landscape of Clear Cell Renal Cell Carcinoma by Single-Cell RNA-seq
Ajaykumar Vishwakarma, Nick Bocherding, M. Chimenti, Purshottam Vishwakarma +5 more
2019bioRxiv7 citations Open access
Semantic Scholar
Numb chin syndrome in acute myeloid leukemia.
R. Jenkins, K. McDonald, C. Greenberg
2012American Journal of the Medical Sciences7 citations
Semantic Scholar
Refining Targeted Therapy Opportunities for BRAF-Mutant Melanoma.
R. Jenkins, D. Barbie
2017Cancer Discovery5 citations
Semantic Scholar
Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade
Arnav Mehta, M. Rucevic, Emmett Sprecher, M. Parikh +24 more
2022bioRxiv4 citations Open access
Semantic Scholar
Distinct Dynamics of Migratory Response to PD-1 and CTLA-4 Blockade Reveals New Mechanistic Insights for Potential T-Cell Reinvigoration following Immune Checkpoint Blockade
Fateme Safaeifard, B. Goliaei, A. Aref, Mohammad-Hadi Foroughmand-Araabi +6 more
2022Cells3 citations Open access
Semantic Scholar

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D. Canals — researcher profile on SciRah

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K. Kitatani — researcher profile on SciRah

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