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D. Huso · SciRah

Researcher profile · Semantic Scholar

D. Huso

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D. Huso — researcher profile on SciRah

h-index: 73
Works: 216
Citations: 20K

Most-cited papers

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Christine M. Dejea, Payam Fathi, J. Craig, A. Boleij +14 more
2018Science990 citations Open access
Semantic Scholar
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis
Andrew C. Goodwin, Christina E. DeStefano Shields, Shaoguang Wu, D. Huso +7 more
2011Proceedings of the National Academy of Sciences of the United States of America592 citations Open access
Semantic Scholar
BACTEROIDES FRAGILIS TOXIN COORDINATES A PRO-CARCINOGENIC INFLAMMATORY CASCADE VIA TARGETING OF COLONIC EPITHELIAL CELLS
Liam Chung, E. T. Orberg, A. Geis, June L. Chan +21 more
2018Cell Host and Microbe539 citations Open access
Semantic Scholar
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses
Nicholas J. Roberts, Linping Zhang, F. Janku, A. Collins +34 more
2014Science Translational Medicine374 citations Open access
Semantic Scholar
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
E. Gallo, D. Loch, J. Habashi, J. Calderón +16 more
2014Journal of Clinical Investigation250 citations Open access
Semantic Scholar
Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
Liam Chung, E. T. Orberg, A. Geis, June L. Chan +21 more
2018Cell Host and Microbe192 citations Open access
Semantic Scholar
Regulatory T cell response to enterotoxigenic Bacteroides fragilis colonization triggers IL-17-dependent colon carcinogenesis
A. Geis, Hongni Fan, Xinqun Wu, Shaoguang Wu +5 more
2015Cancer Discovery170 citations Open access
Semantic Scholar
A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome
J. Doyle, Alexander J. Doyle, Nicole K. Wilson, J. Habashi +16 more
2015eLife131 citations Open access
Semantic Scholar
Redundant innate and adaptive sources of IL-17 production drive colon tumorigenesis
F. Housseau, Shaoguang Wu, E. Wick, Hongni Fan +14 more
2016Cancer Research126 citations Open access
Semantic Scholar
HMGA1: A Master Regulator of Tumor Progression in Triple-Negative Breast Cancer Cells
Sandeep N. Shah, L. Cope, W. Poh, Amy M. Belton +5 more
2013PLoS ONE122 citations Open access
Semantic Scholar
Integrin Modulating Therapies Prevent Fibrosis and Autoimmunity in Genetic Mouse Models of Scleroderma
Elizabeth E. Gerber, E. Gallo, S. Fontana, E. Davis +3 more
2013Nature119 citations Open access
Semantic Scholar
Pericytes promote selective vessel regression to regulate vascular patterning.
Nicole Simonavicius, Matthew Ashenden, A. van Weverwijk, S. Lax +5 more
2012Blood118 citations Open access
Semantic Scholar
A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome
J. Benjamin, Genay O. Pilarowski, Giovanni A. Carosso, Li Zhang +5 more
2016Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis
E. Wick, S. Rabizadeh, E. Albesiano, Xinqun Wu +8 more
2014Inflammatory Bowel Diseases102 citations Open access
Semantic Scholar
HMGA1 Induces Intestinal Polyposis in Transgenic Mice and Drives Tumor Progression and Stem Cell Properties in Colon Cancer Cells
Amy M. Belton, Alexander N. Gabrovsky, Y. Bae, R. Reeves +3 more
2012PLoS ONE101 citations Open access
Semantic Scholar
HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks
Sandeep N. Shah, C. Kerr, L. Cope, Elias T. Zambidis +5 more
2012PLoS ONE99 citations Open access
Semantic Scholar
FLT3-ITD Knock-in Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm
Hai-Hua S. Chu, Diane Heiser, Li Li, I. Kaplan +5 more
2012Cell Stem Cell96 citations Open access
Semantic Scholar
ACTIVATION OF LXR/RXR PATHWAY AMELIORATES LIVER DISEASE IN ATP7B−/− (WILSON DISEASE) MICE
James P. Hamilton, Lahari Koganti, A. Muchenditsi, V. Pendyala +10 more
2015Hepatology95 citations Open access
Semantic Scholar
HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis
A. Schuldenfrei, Amy M. Belton, J. Kowalski, C. Talbot +7 more
2011BMC Genomics87 citations Open access
Semantic Scholar
Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment.
Christina E. DeStefano Shields, S. V. Van Meerbeke, F. Housseau, Hao Wang +4 more
2016Journal of Infectious Diseases82 citations Open access
Semantic Scholar
HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche
Lingling Xian, D. Georgess, Tait H Huso, L. Cope +10 more
2017Nature Communications79 citations Open access
Semantic Scholar
INHIBITION OF HISTONE DEACETYLASE 6 ACTIVITY REDUCES CYST GROWTH IN POLYCYSTIC KIDNEY DISEASE
L. Cebotaru, Qiangni Liu, M. Yanda, C. Boinot +5 more
2016Kidney International78 citations Open access
Semantic Scholar
Polycystin Signaling is Required for Directed Endothelial Cell Migration and Lymphatic Development
Patricia Outeda, D. Huso, Steven A. Fisher, M. Halushka +4 more
2014Cell Reports78 citations Open access
Semantic Scholar
Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.
Sarah M. Greenblatt, Li Li, C. Slape, Bao Nguyen +7 more
2012Blood73 citations Open access
Semantic Scholar
Preclinical and Clinical Evaluation of Intraductally Administered Agents in Early Breast Cancer
V. Stearns, T. Mori, L. Jacobs, N. Khouri +13 more
2011Science Translational Medicine73 citations Open access
Semantic Scholar
Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model
Tara Williamson, Ren-Yuan Bai, V. Staedtke, D. Huso +1 more
2016OncoTarget67 citations Open access
Semantic Scholar
Extracellular matrix protein lumican regulates inflammation in a mouse model of colitis
Kristin Lohr, Hardik Sardana, Seakwoo Lee, Feng Wu +3 more
2011Inflammatory Bowel Diseases65 citations Open access
Semantic Scholar
Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome
J. Habashi, E. MacFarlane, Rustam Bagirzadeh, Caitlin J. Bowen +8 more
2019Science Translational Medicine59 citations Open access
Semantic Scholar
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia
Yiting Lim, Lukasz P. Gondek, Li Li, Qiu-Ju Wang +13 more
2015Science Translational Medicine58 citations Open access
Semantic Scholar
A nanoparticle formulation that selectively transfects metastatic tumors in mice
Jian Yang, W. Hendricks, Guo-Sheng Liu, J. McCaffery +4 more
2013Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
A nephron-based model of the kidneys for macro-to-micro α-particle dosimetry
R. Hobbs, Hong Song, D. Huso, Margaret H. Sundel +1 more
2012Physics in Medicine and Biology58 citations Open access
Semantic Scholar
Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways
P. Wang, S.-H. Chen, Wei-Chien Hung, C. Paul +5 more
2014Oncogene56 citations Open access
Semantic Scholar
Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis
Matthew R. Dallas, Guo-Sheng Liu, Wei-Chiang Chen, S. N. Thomas +3 more
2012The FASEB Journal56 citations Open access
Semantic Scholar
p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.
Yingli Wang, Xue-Yan Zhou, Kurun Oberoi, R. Phelps +11 more
2012Journal of Clinical Investigation55 citations Open access
Semantic Scholar
Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations.
Yong Soon Chun, S. Bisht, Venugopal Chenna, Dipankar Pramanik +10 more
2012Carcinogenesis52 citations Open access
Semantic Scholar
The Mesenchymal Stem Cell Marker CD248 (Endosialin) Is a Negative Regulator of Bone Formation in Mice
A. Naylor, Eman Azzam, S. Smith, A. Croft +10 more
2012Arthritis & Rheumatism50 citations Open access
Semantic Scholar
Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.
Li Li, Emily Bailey, Sarah M. Greenblatt, D. Huso +1 more
2011Blood47 citations Open access
Semantic Scholar
Combined treatment with epigenetic, differentiating, and chemotherapeutic agents cooperatively targets tumor-initiating cells in triple negative breast cancer
V. Merino, N. Nguyen, Kideok Jin, H. Sadik +16 more
2016Cancer Research46 citations Open access
Semantic Scholar
A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.
Dong-Yan Liu, Connie J. Wang, D. Judge, M. Halushka +11 more
2014Journal of the American Society of Nephrology44 citations Open access
Semantic Scholar
Impaired Skeletal Muscle Regeneration in the Absence of Fibrosis during Hibernation in 13-Lined Ground Squirrels
Eva Andrés-Mateos, R. Mejías, A. Soleimani, B. Lin +10 more
2012PLoS ONE40 citations Open access
Semantic Scholar
G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
A. Boleij, Payam Fathi, W. Dalton, Ben Park +11 more
2021Communications Biology39 citations Open access
Semantic Scholar
Heterotopic Ossifications in a Mouse Model of Albright Hereditary Osteodystrophy
D. Huso, Sarah Edie, M. Levine, W. Schwindinger +3 more
2011PLoS ONE38 citations Open access
Semantic Scholar
Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey
Joon-Tae Park, Nicole Johnson, Shu Liu, Mathieu Lévesque +7 more
2014Oncogene37 citations Open access
Semantic Scholar
The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma
J. Hillion, Shamayra S. Smail, F. di Cello, Amy M. Belton +11 more
2012Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]34 citations Open access
Semantic Scholar
Genetic Deletion of the Stromal Cell Marker CD248 (Endosialin) Protects against the Development of Renal Fibrosis
S. Smith, A. Croft, H. Morris, A. Naylor +4 more
2015Nephron33 citations Open access
Semantic Scholar
FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice
Emily Bailey, Li Li, A. Duffield, Hayley S. Ma +2 more
2013Proceedings of the National Academy of Sciences of the United States of America33 citations Open access
Semantic Scholar
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease
R. Rau, D. Magoon, Sarah M. Greenblatt, Li Li +9 more
2013Experimental Hematology33 citations Open access
Semantic Scholar
Effective treatment of ductal carcinoma in situ with a HER-2-targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer
Takahiro Yoshida, Kideok Jin, Hong Song, Sunju Park +8 more
2016OncoTarget32 citations Open access
Semantic Scholar
Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1
Benjamin C. Orsburn, Beatriz Escudero, M. Prakash, Silvia I. Gesheva +3 more
2010Molecular and Cellular Biology32 citations Open access
Semantic Scholar
The High Mobility Group A1 (HMGA1) Gene is Highly Overexpressed in Human Uterine Serous Carcinomas and Carsinosarcomas and Drives Matrix Metalloproteinase-2 (MMP-2) in a Subset of Tumors
J. Hillion, Sujayita Roy, M. Heydarian, L. Cope +10 more
2016Gynecologic Oncology31 citations Open access
Semantic Scholar

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