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S. Lax · SciRah

Researcher profile · Semantic Scholar

S. Lax

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S. Lax — researcher profile on SciRah

h-index: 21
Works: 51
Citations: 1,874

Most-cited papers

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)
R. Dancer, D. Parekh, S. Lax, Vijay K. D'Souza +18 more
2015Thorax288 citations Open access
Semantic Scholar
Fibroblasts as novel therapeutic targets in chronic inflammation
S. Flavell, T. Hou, S. Lax, A. Filer +2 more
2008British Journal of Pharmacology189 citations Open access
Semantic Scholar
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.
Jessica R. Hitchcock, C. Cook, S. Bobat, E. Ross +19 more
2015Journal of Clinical Investigation171 citations Open access
Semantic Scholar
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis
J. Rayes, S. Lax, Surasak Wichaiyo, S. Watson +6 more
2017Nature Communications139 citations Open access
Semantic Scholar
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway.
R. McMullan, S. Lax, Vicki H. Robertson, D. Radford +6 more
2003Current Biology122 citations Open access
Semantic Scholar
Pericytes promote selective vessel regression to regulate vascular patterning.
Nicole Simonavicius, Matthew Ashenden, A. van Weverwijk, S. Lax +5 more
2012Blood118 citations Open access
Semantic Scholar
Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha
Greg Parsonage, A. Filer, Magdalena Bik, D. Hardie +10 more
2008Arthritis Research & Therapy105 citations Open access
Semantic Scholar
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
M. Chimen, Aigli Evryviadou, Clare L Box, M. Harrison +21 more
2019Haematologica93 citations Open access
Semantic Scholar
CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair
S. Lax, T. Hou, E. Jenkinson, M. Salmon +5 more
2007FEBS Letters58 citations
Semantic Scholar
Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse
S. Lax, J. Rayes, Surasak Wichaiyo, Elizabeth J. Haining +8 more
2017American Journal of Physiology - Lung cellular and Molecular Physiology56 citations Open access
Semantic Scholar
Lysophosphatidic acid induces process retraction in CG‐4 line oligodendrocytes and oligodendrocyte precursor cells but not in differentiated oligodendrocytes
J. Dawson, N. Hotchin, S. Lax, M. Rumsby
2003Journal of Neurochemistry56 citations
Semantic Scholar
Vitamin D deficiency in human and murine sepsis
D. Parekh, J. Patel, A. Scott, S. Lax +8 more
2017Critical Care Medicine55 citations Open access
Semantic Scholar
The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent
J. Rayes, Soumaya Jadoui, S. Lax, Angèle Gros +8 more
2018Haematologica53 citations Open access
Semantic Scholar
Thymic function is maintained during Salmonella-induced atrophy and recovery
E. Ross, R. Coughlan, A. Flores-Langarica, S. Lax +13 more
2012Journal of Immunology43 citations Open access
Semantic Scholar
The stromal cell antigen CD248 (endosialin) is expressed on naive CD8+ human T cells and regulates proliferation
Debbie L. Hardie, Mathew J. Baldwin, A. Naylor, O. Haworth +7 more
2011Immunology42 citations Open access
Semantic Scholar
The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion
S. Lax, Debbie L. Hardie, A. Wilson, Michael R. Douglas +4 more
2010European Journal of Immunology42 citations Open access
Semantic Scholar
A Novel Role for PECAM-1 (CD31) in Regulating Haematopoietic Progenitor Cell Compartmentalization between the Peripheral Blood and Bone Marrow
E. Ross, Sylvie D. Freeman, Yan Zhao, T. Dhanjal +10 more
2008PLoS ONE40 citations Open access
Semantic Scholar
Using a non-invasive assessment of lung injury in a murine model of acute lung injury
S. Lax, M. R. Wilson, M. Takata, D. Thickett
2014BMJ Open Respiratory Research36 citations Open access
Semantic Scholar
Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO): study protocol for a randomised placebo controlled trial
D. Parekh, R. Dancer, S. Lax, M. Cooper +7 more
2013Trials36 citations Open access
Semantic Scholar
Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice
Surasak Wichaiyo, S. Lax, S. Montague, Zhi Li +6 more
2019Haematologica33 citations Open access
Semantic Scholar
CD248 expression on mesenchymal stromal cells is required for post-natal and infection-dependent thymus remodelling and regeneration
S. Lax, E. Ross, Andrea J. White, J. Marshall +6 more
2012FEBS Open Bio26 citations Open access
Semantic Scholar
Lymphatic blood filling in CLEC-2-deficient mouse models
Elizabeth J. Haining, Kate L. Lowe, Surasak Wichaiyo, Raghu P. Kataru +10 more
2020Platelets18 citations Open access
Semantic Scholar
Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS
R. Mahida, S. Lax, C. Bassford, A. Scott +8 more
2023Frontiers in Immunology15 citations Open access
Semantic Scholar
Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment.
Rachel J. Stapley, Christopher W. Smith, Elizabeth J. Haining, A. Bacon +6 more
2021Blood Advances10 citations Open access
Semantic Scholar
Effect of anti-podoplanin antibody administration during lipopolysaccharide-induced lung injury in mice
S. Lax, J. Rayes, D. Thickett, S. Watson
2017BMJ Open Respiratory Research10 citations Open access
Semantic Scholar
The reverse target sign in liver disease: a potential ultrasound feature in cirrhotic liver nodules characterization.
G. J. Kraus, P. Schedlbauer, S. Lax, D. Zebedin +1 more
2005British Journal of Radiology9 citations
Semantic Scholar
MRI appearance of gestational choriocarcinoma within the myometrium.
D. Szolar, G. Ranner, S. Lax, K. Preidler
1994European Journal of Radiology7 citations
Semantic Scholar
[Non-granulomatous prostatitis: MRI image with endorectal surface coil ("Endo-MRI")].
D. Szolar, G. Ranner, K. Preidler, S. Lax
1995Aktuelle Radiologie5 citations
Semantic Scholar
S98 Vitamin D deficiency increases bacterial load in a murine model of sepsis-induced lung injury
D. Parekh, R. C. A. Dancer, S. Lax, G. Perkins +1 more
2013Thorax3 citations Open access
Semantic Scholar
Vitamin D deficiency and bacterial load in a murine model of sepsis-induced lung injury
D. Parekh, S. Lax, R. Dancer, G. Perkins +1 more
20141 citations
Semantic Scholar
S54 The Role of Pre-Receptor Glucocorticoid Metabolism in Regulating the Severity and Persistence of Murine Lung Injury
S. Lax, Wilson, M. Takata, P. Stewart +1 more
2012Thorax1 citations Open access
Semantic Scholar
Cerebrospinal fluid shunting or dural venous sinus stenting to preserve vision in idiopathic intracranial hypertension (IIH Intervention): protocol for an open-label, multicentre, randomised controlled phase IIb trial
G. Tsermoulas, S. Mollan, Victoria Homer, C. Kristunas +28 more
2026BMJ Open0 citations Open access
Semantic Scholar
Response to Gultekin et al. regarding SECRAB trial toxicity.
I. Fernando, S. Lax, I. Ahmed
2020Radiotherapy and Oncology0 citations Open access
Semantic Scholar
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis
J. Rayes, S. Lax, Surasak Wichaiyo, S. Watson +6 more
2017Nature Communications0 citations Open access
Semantic Scholar
Platelet CLEC-2 protects against lung injury via effects of its ligand 1 podoplanin on inflammatory alveolar macrophages in the mouse 2
S. Lax, J. Rayes, Surasak Wichaiyo, Elizabeth J. Haining +8 more
20170 citations
Semantic Scholar
LSC Abstract – The role of platelet-expressed C-type lectin-like receptor-2 in regulating the severity of murine lung injury
S. Lax, J. Rayes, D. Thickett, S. Watson
20160 citations
Semantic Scholar
LSC Abstract – Vitamin D deficiency is associated with and influences the severity of human and murine sepsis
D. Parekh, J. Patel, S. Lax, A. Scott +3 more
20160 citations
Semantic Scholar
University of Birmingham Vitamin D deficiency in human and murine sepsis
D. Parekh, Jaimin M. Patel, A. Scott, S. Lax +8 more
20160 citations
Semantic Scholar
University of Birmingham Using a non-invasive assessment of lung injury in a murine model of acute lung injury
S. Lax, M. R. Wilson, M. Takata, D. Thickett
20140 citations
Semantic Scholar
Effects of vitamin D deficiency in a murine model of sepsis-induced lung injury
D. Parekh, S. Lax, R. Dancer, G. Perkins +1 more
20140 citations
Semantic Scholar
Therapeutic vitamin D reduces the severity of lipopolysaccharide-induced murine lung injury
D. Parekh, R. Dancer, G. Perkins, D. Thickett +1 more
20140 citations
Semantic Scholar
The role of pre-receptor glucocorticoid metabolism in regulating the severity and persistence of murine lung injury
S. Lax, M. R. Wilson, M. Takata, Paul M. Stewart +1 more
2013European Respiratory Journal0 citations
Semantic Scholar
The role of vitamin D in regulating the severity and duration of murine lung injury
S. Lax, D. Parekh, R. Dancer, D. Thickett
2013European Respiratory Journal0 citations
Semantic Scholar
University of Birmingham Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO) : study protocol for a randomised placebo controlled trial
D. Parekh, R. Dancer, S. Lax, M. Cooper +7 more
20130 citations
Semantic Scholar
The role of pre-receptor glucocorticoid metabolism in regulating the severity of ALI
S. Lax, Micheal C. Wilson, M. Takata, D. Thickett
20120 citations
Semantic Scholar
S57 The Role of Vitamin D Deficiency in Regulating the Severity and Duration of Murine Lung Injury
S. Lax, D. Parekh, R. Dancer, D. Thickett
2012Thorax0 citations
Semantic Scholar
S4 Anti-Inflammatory Effects of Vitamin D Are Influenced More by Genetic Background Than Mycobacterial Infection
Gemma Hawthorne, Helen R Mujakperuo, S. Lax, Laura McGowan +3 more
2012Thorax0 citations Open access
Semantic Scholar
Cover Picture: Eur. J. Immunol. 7/10
S. Lax, D. Hardie, A. Wilson, Michael R. Douglas +4 more
20100 citations Open access
Semantic Scholar
Platelet Endothelial Cell Adhesion Molecule (PECAM)-1 modulates SDF-1alpha/CXCR4 responses of hematopoietic stem cells
E. Ross, Sylvie D. Freeman, Yan Zhao, T. Dhanjal +9 more
20090 citations
Semantic Scholar
Generation and characterisation of stromal specific antibodies and the identification of a novel subset of CD45+expressing mesenchymal cells implicated in chronic inflammation
D. Hardie, T. Hou, S. Lax, S. Halder +4 more
20050 citations
Semantic Scholar

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D. Thickett×16
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D. Parekh×12
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D. Parekh — researcher profile on SciRah
S. Watson×12
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S. Watson — researcher profile on SciRah
R. Dancer×11
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G. Perkins — researcher profile on SciRah

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J. Rayes — researcher profile on SciRah

Surasak Wichaiyo×7

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C. Buckley — researcher profile on SciRah

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T. Hou — researcher profile on SciRah

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