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Patricia Outeda · SciRah

Researcher profile · Semantic Scholar

Patricia Outeda

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Patricia Outeda — researcher profile on SciRah

h-index: 14
Works: 44
Citations: 1,028

Most-cited papers

The Polycystin complex mediates WNT/Ca2+ signaling
Seokho Kim, Hong-Guang Nie, V. Nesin, Uyen Tran +7 more
2016Nature Cell Biology159 citations Open access
Semantic Scholar
Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.
Sarah R. Senum, Ying Li, K. Benson, G. Joli +24 more
2021American Journal of Human Genetics150 citations Open access
Semantic Scholar
Ciliary membrane proteins traffic through the Golgi via aRabep1/GGA1/Arl3-dependent mechanism
Hyunho Kim, Hang-Xue Xu, Q. Yao, Wei-Zhe Li +10 more
2014Nature Communications112 citations Open access
Semantic Scholar
Pkd1 and Pkd2 Are Required for Normal Placental Development
M. García-González, Patricia Outeda, Qin Zhou, Fang Zhou +6 more
2010PLoS ONE90 citations Open access
Semantic Scholar
A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed
Cheng-Chao Lin, Mahiro Kurashige, Yi Liu, T. Terabayashi +16 more
2018Scientific Reports87 citations Open access
Semantic Scholar
INHIBITION OF HISTONE DEACETYLASE 6 ACTIVITY REDUCES CYST GROWTH IN POLYCYSTIC KIDNEY DISEASE
L. Cebotaru, Qiangni Liu, M. Yanda, C. Boinot +5 more
2016Kidney International78 citations Open access
Semantic Scholar
Polycystin Signaling is Required for Directed Endothelial Cell Migration and Lymphatic Development
Patricia Outeda, D. Huso, Steven A. Fisher, M. Halushka +4 more
2014Cell Reports78 citations Open access
Semantic Scholar
A novel pattern of mutation in uromodulin disorders: autosomal dominant medullary cystic kidney disease type 2, familial juvenile hyperuricemic nephropathy, and autosomal dominant glomerulocystic kidney disease.
X. Lens, Julio F Banet, Patricia Outeda, Vicente Barrio-Lucía
2005American Journal of Kidney Diseases53 citations
Semantic Scholar
A novel model of autosomal recessive polycystic kidney questions the role of the Fibrocystin C-terminus in disease mechanism
Patricia Outeda, L. F. Menezes, Erum A. Hartung, Stacey Bridges +8 more
2017Kidney International52 citations Open access
Semantic Scholar
TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease
Adrián Cordido, Laura Núñez-González, J. Martínez-Moreno, Olaya Lamas-González +12 more
2021Journal of the American Society of Nephrology34 citations Open access
Semantic Scholar
NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology
J. Kaimori, Cheng-Chao Lin, Patricia Outeda, M. García-González +15 more
2017Scientific Reports29 citations Open access
Semantic Scholar
Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis
R. Walker, Qin Yao, Hang-Xue Xu, Anthony Maranto +9 more
2023Nature Communications20 citations Open access
Semantic Scholar
Multiomics profiling of mouse polycystic kidney disease progression at a single-cell resolution
Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu, Monica Chang-Panesso +7 more
2024Proceedings of the National Academy of Sciences of the United States of America15 citations Open access
Semantic Scholar
GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD
E. Dixon, Demetri S Maxim, Victoria L. Halperin Kuhns, Allison C. Lane-Harris +5 more
2020Journal of Cell Science14 citations Open access
Semantic Scholar
Polycystin-2 dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease.
Hyun Jun Jung, E. Dixon, Richard Coleman, T. Watnick +5 more
2023Physiological Genomics11 citations Open access
Semantic Scholar
Polycystin-1 dependent regulation of polycystin-2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum
Qin Yao, Patricia Outeda, Hang-Xue Xu, R. Walker +5 more
2021The FASEB Journal10 citations Open access
Semantic Scholar
SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis
K. Asrani, A. Amaral, Juhyung Woo, S. Abadchi +16 more
2025Nature Communications8 citations Open access
Semantic Scholar
Novel ARPKD mouse model with near complete deletion of Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus has multiple phenotypes but no renal cysts
Yumiko Ishimoto, L. F. Menezes, Fang Zhou, Teruhiko Yoshida +8 more
2023Kidney International6 citations Open access
Semantic Scholar
Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat.
P. Kaisaki, C. Bergmann, Joanna H. Brown, Patricia Outeda +5 more
2008European Journal of Medical Genetics6 citations
Semantic Scholar
A genetic screen in Drosophila reveals an unexpected role for the KIP1 ubiquitination-promoting complex in male fertility
Wei-Zhe Li, Jin-Qing Liang, Patricia Outeda, Stacey L. Turner +2 more
2020PLoS Genetics5 citations Open access
Semantic Scholar
Inactivation of Pkd2 in adult mice results in delayed cyst formation and identifies sex as a major modifier of disease severity
Patricia Outeda, Perry Summers, Denis Basquin, Rui-Zhen Xu +3 more
2025Kidney International4 citations Open access
Semantic Scholar
SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis
K. Asrani, A. Amaral, Juhyung Woo, S. Abadchi +13 more
2024bioRxiv4 citations Open access
Semantic Scholar
Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution
Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu, Monica Chang-Panesso +7 more
2024bioRxiv2 citations Open access
Semantic Scholar
Versatile HaloTag Resource Illuminates PKD2 Localization and Turnover
Zhang Li, Courtney J. Haycraft, Mandy J. Croyle, Daniel Hudson +18 more
2026Journal of the American Society of Nephrology1 citations Open access
Semantic Scholar
Hyperosmotic stimuli activate polycystin proteins to aid in urine concentration
K. M. Márquez-Nogueras, R. M. Knutila, Virdjinija Vuchkovska, Charlie Yang +3 more
2025JCI Insight1 citations Open access
Semantic Scholar
A novel gene therapy for ARPKD based on CFTR.
Cristian Ciobanu, Patricia Outeda, W. Guggino, L. Cebotaru
2025American Journal of Physiology - Gastrointestinal and Liver Physiology1 citations Open access
Semantic Scholar
Aberrant Cellular Pathways in PKD
Alison Grazioli, Patricia Outeda, T. Watnick
20181 citations
Semantic Scholar
PKD2 structural destabilization drives primary cilia degeneration and ADPKD pathogenicity
Patricia Outeda, Qin-Zhe Wang, T. Vien, Orhi Esarte Palomero +6 more
2026bioRxiv0 citations Open access
Semantic Scholar
Targeting microtubule dynamics with mebendazole slows disease progression in ADPKD mice
Eilley W. Barron, Patricia Outeda, Qin Yao, T. Watnick +1 more
2026Scientific Reports0 citations Open access
Semantic Scholar
Abstract 3943: SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis
K. Asrani, A. Amaral, Juhyung Woo, S. Abadchi +13 more
2025Cancer Research0 citations
Semantic Scholar
EB1-Regulated Microtubule Dynamics Drive Cyst Formation in ADPKD
Valeriu Cebotaru, Eilley W. Barron, Patricia Outeda, Qin Yao +1 more
2025Journal of the American Society of Nephrology0 citations
Semantic Scholar
Creating new in vitro models to examine the role of Pkd1 in cell and tubular physiology
Victoria Halperin Kuhns, Ava M. Zapf, Patricia Outeda, T. Watnick +1 more
2024Physiology0 citations
Semantic Scholar
Cell State Transition Associated with Cyst Development in Autosomal Dominant Polycystic Kidney Disease
Hyun Jun Jung, Patricia Outeda, O. Woodward, T. Watnick +1 more
2024Journal of the American Society of Nephrology0 citations
Semantic Scholar
Cleavage of PC1 Is Not Required for Embryonic Vasculature Development
Denis Basquin, Patricia Outeda, T. Watnick, Feng Qian
2023Journal of the American Society of Nephrology0 citations
Semantic Scholar
The Direct Physical Interaction Between Calcium-Sensing Receptor and Polycystin-2: Implication in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Patricia Outeda, Courtney J. Haycraft, Denis Basquin, Pamela V. Tran +5 more
2023Journal of the American Society of Nephrology0 citations
Semantic Scholar
#4181 THE AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE PROTEIN, FPC, RELEASES MITOCHONDRIA LOCALISING FRAGMENTS INVOLVED IN PREVENTING CYSTOGENESIS
R. Walker, Hang-Xue Xu, A. Maranto, Patricia Outeda +2 more
2023Nephrology, Dialysis and Transplantation0 citations Open access
Semantic Scholar
Transcriptomic Analysis of Pkd2-Deficient Kidneys Shows Altered Metabolic and Cytoskeleton Pathways Similar to Pkd1 Models and Evidence of an Increased Inflammatory Response
Patricia Outeda, Luis F. Menezes, Denis Basquin, T. Watnick
2023Journal of the American Society of Nephrology0 citations
Semantic Scholar
Addition of an N-Terminal SNAP-Tag Induces a Novel Hypomorphic Pkd1 Allele
Stephen C. Parnell, Pamela V. Tran, G. Prasad, J. Unger +5 more
2023Journal of the American Society of Nephrology0 citations
Semantic Scholar
Loss of Cross-Talk Between Polycystin 1 and LSD1 Promotes Cyst Growth Through Interaction With Ataxia Telangiectasia Mutated and Phase Separation Mechanism in Autosomal Dominant Polycystic Kidney Disease
Courtney J. Haycraft, Mandy J. Croyle, Laura J. Lambert, Patricia Outeda +10 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
Generation of Mice Expressing an N-Terminal SNAP-Tagged Pkd1 Allele
Stephen C. Parnell, Pamela V. Tran, Heather A. Riddle, Wei Wang +6 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
Mice With a Genomic Deletion of Pkhd1 Exons 3-67 Have Minimal Renal Manifestations but Evidence of Transcriptional Network Changes by snRNA Sequencing
Yumiko Ishimoto, Luis F. Menezes, Fang Zhou, Teruhiko Yoshida +3 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
Cleavage of Pkhd1 Results in a Small Fragment That Localizes and Functions Within Mitochondria
R. Walker, Anthony Maranto, Patricia Outeda, Hang-Xue Xu +2 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
Loss of Polycystin Function in Lymphatic Cells Impair CTP1a Expression and Fatty Acid Uptake
Denis Basquin, Jin-Qing Liang, T. Watnick, Patricia Outeda
2021Journal of the American Society of Nephrology0 citations
Semantic Scholar
Methods to Study the Vasculature in ADPKD
Patricia Outeda, T. Watnick
2019Polycystic Kidney Disease0 citations
Semantic Scholar

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