Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Paul M. Titchenell · SciRah

Researcher profile · Semantic Scholar

Paul M. Titchenell

Share profile

Paul M. Titchenell — researcher profile on SciRah

h-index: 25
Works: 62
Citations: 3,794

Most-cited papers

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
Rachel J. Perry, J. Camporez, R. Kursawe, Paul M. Titchenell +16 more
2015Cell678 citations Open access
Semantic Scholar
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
Steven Zhao, Cholsoon Jang, Joyce Liu, Kahealani Uehara +13 more
2020Nature496 citations Open access
Semantic Scholar
Unraveling the Regulation of Hepatic Metabolism by Insulin
Paul M. Titchenell, M. Lazar, M. Birnbaum
2017Trends in endocrinology and metabolism372 citations Open access
Semantic Scholar
Resolving the Paradox of Hepatic Insulin Resistance
Dominic Santoleri, Paul M. Titchenell
2018Cellular and Molecular Gastroenterology and Hepatology284 citations Open access
Semantic Scholar
Hepatocyte Insulin Signaling is Required for Feeding-Induced Lipogenesis but Dispensable for the Suppression of Glucose Production
Paul M. Titchenell, W. Quinn, Ming-Jian Lu, Q. Chu +7 more
2016Cell Metabolism246 citations Open access
Semantic Scholar
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
Kashyap A. Patel, M. Foretz, A. Marion, D. Campbell +14 more
2014Nature Communications163 citations Open access
Semantic Scholar
Hepatic Insulin Signaling is Dispensable for Suppression of Glucose Output by Insulin in Vivo
Paul M. Titchenell, Q. Chu, B. Monks, M. Birnbaum
2015Nature Communications161 citations Open access
Semantic Scholar
The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis
Natasha Jaiswal, M. Gavin, W. Quinn, Timothy S. Luongo +3 more
2019Molecular Metabolism157 citations Open access
Semantic Scholar
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1
Bridget S. Gosis, Shogo Wada, Chelsea L. Thorsheim, Kristina Li +14 more
2022Science153 citations Open access
Semantic Scholar
Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism
Elizabeth Nunn, Natasha Jaiswal, M. Gavin, Kahealani Uehara +8 more
2024Molecular Metabolism111 citations Open access
Semantic Scholar
SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding
Hagoon Jang, G. Lee, C. Selby, Gung Lee +8 more
2016Nature Communications92 citations Open access
Semantic Scholar
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Won Dong Lee, Daniel R. Weilandt, Lingfan Liang, Michael R. MacArthur +15 more
2025Cell Metabolism85 citations Open access
Semantic Scholar
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion
W. Quinn, Min Wan, Swapnil V. Shewale, R. Gelfer +3 more
2017Journal of Clinical Investigation85 citations Open access
Semantic Scholar
AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology
Natasha Jaiswal, Matthew J. Gavin, E. Loro, Jaimarie Sostre-Colón +8 more
2021Journal of Cachexia, Sarcopenia and Muscle75 citations Open access
Semantic Scholar
Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
Anthony R. Angueira, Suzanne N. Shapira, Jeff Ishibashi, Samay Sampat +6 more
2020Cell Reports68 citations Open access
Semantic Scholar
Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP
R. Papazyan, Zheng Sun, Yong Hoon Kim, Paul M. Titchenell +8 more
2016Cell Metabolism68 citations Open access
Semantic Scholar
Insulin Regulation of Hepatic Lipid Homeostasis
Kahealani Uehara, Dominic Santoleri, Anna E. Garcia Whitlock, Paul M. Titchenell
2023Comprehensive Physiology67 citations
Semantic Scholar
ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules
Dhanunjay Mukhi, Lingzhi Li, Hong-Bo Liu, T. Doke +15 more
2023Journal of Clinical Investigation47 citations Open access
Semantic Scholar
Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis
Kahealani Uehara, Jaimarie Sostre-Colón, Matthew J. Gavin, Dominic Santoleri +3 more
2022Cellular and Molecular Gastroenterology and Hepatology44 citations Open access
Semantic Scholar
Bempedoic acid suppresses diet-induced hepatic steatosis independent of ATP-citrate lyase
Joyce Y. Liu, Ramya S. Kuna, Laura V. Pinheiro, Phuong T. T. Nguyen +18 more
2024Cell Metabolism41 citations Open access
Semantic Scholar
Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function.
Ya-Chen Shen, Yvonne Su, F. J. Silva, Angela H. Weller +5 more
2020Cell Reports39 citations Open access
Semantic Scholar
MondoA drives muscle lipid accumulation and insulin resistance.
B. Ahn, Shibiao Wan, Natasha Jaiswal, Rick B. Vega +5 more
2019JCI Insight37 citations Open access
Semantic Scholar
A consensus guide to preclinical indirect calorimetry experiments
Alexander S. Banks, David B. Allison, Thierry Alquier, Ansarullah +75 more
2025Nature Metabolism35 citations Open access
Semantic Scholar
Loss of FOXO transcription factors in the liver mitigates stress-induced hyperglycemia
Anna E. Garcia Whitlock, Jamarie Sostre-Colón, Matthew J. Gavin, N. Martin +3 more
2021Molecular Metabolism27 citations Open access
Semantic Scholar
Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms
Jaimarie Sostre-Colón, Kahealani Uehara, Anna E. Garcia Whitlock, Matthew J. Gavin +4 more
2021Cell Reports25 citations Open access
Semantic Scholar
Re-epithelialization of Diabetic Skin and Mucosal Wounds is Rescued by Treatment with Epigenetic Inhibitors.
Bo Yang, Stella Alimperti, Michael V. Gonzalez, T. Dentchev +7 more
2023Diabetes21 citations Open access
Semantic Scholar
siRNA-mediated knockdown of h-caldesmon in vascular smooth muscle.
Elaine M. Smolock, Danielle M. Trappanese, Shao-Hua Chang, Tanchun Wang +2 more
2009American Journal of Physiology. Heart and Circulatory Physiology17 citations Open access
Semantic Scholar
Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism
Delfin G. Buyco, Joseph L. Dempsey, E. Scorletti, Sookyoung Jeon +11 more
2023PLoS ONE16 citations Open access
Semantic Scholar
mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
Kahealani Uehara, W. Lee, Megan Stefkovich, Dipsikha Biswas +9 more
2024Journal of Clinical Investigation13 citations Open access
Semantic Scholar
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
K. Trang, M. Pahl, J. Pippin, Chun Su +23 more
2023medRxiv13 citations Open access
Semantic Scholar
The Polycomb protein, Bmi1, regulates insulin sensitivity
Corey E. Cannon, Paul M. Titchenell, D. Groff, Abdelfattah El Ouaamari +3 more
2014Molecular Metabolism13 citations Open access
Semantic Scholar
Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity
Bam Paneru, Julia Chini, Sam J. McCright, Nicole DeMarco +8 more
2024Nature Communications12 citations Open access
Semantic Scholar
Ppp1r3b is a metabolic switch that shifts hepatic energy storage from lipid to glycogen
K. Creasy, M. B. Mehta, C. Schneider, J. Park +8 more
2025Science Advances7 citations Open access
Semantic Scholar
Acute deletion of the FOXO1-dependent hepatokine FGF21 does not alter basal glucose homeostasis or lipolysis in mice.
Jaimarie Sostre-Colón, Matthew J. Gavin, Dominic Santoleri, Paul M. Titchenell
2022Endocrinology7 citations Open access
Semantic Scholar
Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity
Dominic Santoleri, Hee-Woong Lim, M. J. Emmett, J. Stoute +7 more
2022iScience5 citations Open access
Semantic Scholar
3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility
K. Trang, P. Sharma, Laura Cook, Zachary Mount +26 more
2024medRxiv4 citations Open access
Semantic Scholar
Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data
Maria C. Costanzo, B. Akolkar, M. Claussnitzer, J. C. Florez +16 more
2025Diabetes3 citations Open access
Semantic Scholar
854-P: ENT-03, a Centrally Acting Endogenous Spermine Bile Acid with PTP1B Inhibitory Activity, Has Potent Effects on Metabolism and Weight in a Mouse Model of Diet-Induced Obesity (DIO)
Denise Barbut, Joseph A. Baur, Paul M. Titchenell, James G. Davis +4 more
2023Diabetes3 citations
Semantic Scholar
Single-cell spatial mapping of human kidney development implicates the microenvironment in guiding cell fate decisions
Jonathan Levinsohn, Samuel Grindel, Bernhard Dumoulin, A. Abedini +20 more
2026Nature Genetics2 citations Open access
Semantic Scholar
Location Matters: Mitochondrial Arginase 2 as a Treatment for Metabolic Disease?
Megan Stefkovich, Paul M. Titchenell
2024Cellular and Molecular Gastroenterology and Hepatology2 citations Open access
Semantic Scholar
Curing Fatty Liver with Oxysterols?
Kahealani Uehara, Paul M. Titchenell
2022Cellular and Molecular Gastroenterology and Hepatology2 citations Open access
Semantic Scholar
Glutamine Breakdown as a Potential Metabolic Biomarker for Nonalcoholic Steatohepatitis
Anna E. Garcia Whitlock, Paul M. Titchenell
2020Cellular and Molecular Gastroenterology and Hepatology2 citations Open access
Semantic Scholar
University of Dundee The LKB 1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
Kashyap A. Patel, M. Foretz, A. Marion, D. Campbell +14 more
20142 citations
Semantic Scholar
Sex-Based Differences in Imaging-Derived Body Composition and Their Association with Clinical Malnutrition in Abdominal Surgery Patients
R. Damani, Shubha Vasisht, V. Luks, G. Vargas +7 more
2026Nutrients1 citations Open access
Semantic Scholar
3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility
K. Trang, P. Sharma, Laura Cook, Zachary Mount +26 more
2025Genome Biology1 citations Open access
Semantic Scholar
Single-Cell Spatial Mapping of Human Kidney Development Reveals the Critical Role of the Local Microenvironment in Cell Fate Decisions
Jonathan Levinsohn, Samuel Grindel, Bernhard Dumoulin, A. Abedini +17 more
2025bioRxiv1 citations
Semantic Scholar
Shared and unique 3D genomic features of substance use disorders across multiple cell types
K. Trang, A. Chesi, S. Toikumo, J. Pippin +19 more
2024medRxiv1 citations Open access
Semantic Scholar
Acute AKT signaling increases glucose phosphorylation and contribution to glycogen in hepatocytes
Megan Stefkovich, Won Dong Lee, Talia Coopersmith, Joseph A. Baur +2 more
2026iScience0 citations Open access
Semantic Scholar
Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant
Dominic Santoleri, Sarah Traynor, Ryan P. Calhoun, Matthew J. Gavin +3 more
2026bioRxiv0 citations Open access
Semantic Scholar
Divergent AKT Signalling Mechanisms Regulate GLUT4 Translocation and Glucose Uptake in Skeletal Muscle and Adipose Tissue
Natasha Jaiswal, Matthew J. Gavin, Louise Lantier, O. Ong +2 more
2026Journal of Cachexia, Sarcopenia and Muscle0 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Kahealani Uehara×11
Invite
Kahealani Uehara — researcher profile on SciRah
M. Birnbaum×9
Invite
M. Birnbaum — researcher profile on SciRah
Dominic Santoleri×8
Invite
Dominic Santoleri — researcher profile on SciRah
Matthew J. Gavin×8
Invite
Matthew J. Gavin — researcher profile on SciRah

Jaimarie Sostre-Colón×8

Invite

Jaimarie Sostre-Colón — researcher profile on SciRah

Natasha Jaiswal×6

Invite

Natasha Jaiswal — researcher profile on SciRah

Patrick Seale×6

Invite

Patrick Seale — researcher profile on SciRah

Joseph A. Baur×5

Invite

Joseph A. Baur — researcher profile on SciRah

Anna E. Garcia Whitlock×5

Invite

Anna E. Garcia Whitlock — researcher profile on SciRah

Invite

M. Lazar — researcher profile on SciRah

Invite

W. Quinn — researcher profile on SciRah

Megan Stefkovich×4

Invite

Megan Stefkovich — researcher profile on SciRah