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Rachel J. Perry · SciRah

Researcher profile · Semantic Scholar

Rachel J. Perry

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Rachel J. Perry — researcher profile on SciRah

h-index: 46
Works: 127
Citations: 8,920

Most-cited papers

Regulation of adipose tissue inflammation by interleukin 6
M. Han, Alexis White, Rachel J. Perry, J. Camporez +3 more
2020Proceedings of the National Academy of Sciences of the United States of America310 citations Open access
Semantic Scholar
Metformin Inhibits Gluconeogenesis by a Redox-Dependent Mechanism In Vivo
A. Madiraju, Y. Qiu, Rachel J. Perry, Yasmeen Rahimi +11 more
2018Nature Medicine258 citations Open access
Semantic Scholar
Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents
L. Goedeke, J. Bates, D. Vatner, Rachel J. Perry +10 more
2018Hepatology231 citations Open access
Semantic Scholar
Origin and function of stress-induced IL6 in murine models
H. Qing, R. Desrouleaux, Kavita Israni-Winger, Y. Mineur +8 more
2020Cell212 citations Open access
Semantic Scholar
Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism
Heather A. Ferris, Rachel J. Perry, G. Moreira, Gerald I. Shulman +2 more
2017Proceedings of the National Academy of Sciences of the United States of America205 citations Open access
Semantic Scholar
Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes
K. Sharabi, Hua Lin, Clint D. J. Tavares, John E. Dominy +19 more
2017Cell192 citations Open access
Semantic Scholar
Leptin mediates a glucose-fatty acid cycle to maintain glucose homeostasis in starvation
Rachel J. Perry, Yong-Liang Wang, G. Cline, Aviva Rabin-Court +5 more
2018Cell168 citations Open access
Semantic Scholar
Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans
Nicolás Gómez-Banoy, J. Guseh, Ge Li, Alfonso Rubio-Navarro +21 more
2019Nature Medicine166 citations Open access
Semantic Scholar
IL-27 signalling promotes adipocyte thermogenesis and energy expenditure
Qian Wang, Dehai Li, Guang-Chao Cao, Qi-Ping Shi +31 more
2021Nature157 citations
Semantic Scholar
Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance
Feng He, Yan-Rui Huang, Zhi Song, H. Zhou +4 more
2020Journal of Experimental Medicine148 citations Open access
Semantic Scholar
Glucagon stimulates gluconeogenesis by InsP3R-I mediated hepatic lipolysis
Rachel J. Perry, Dong-Yan Zhang, M. Guerra, Allison L. Brill +16 more
2020Nature141 citations Open access
Semantic Scholar
Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation
S. Caprio, Rachel J. Perry, R. Kursawe
2017Gastroenterology138 citations Open access
Semantic Scholar
Mechanisms by which adiponectin reverses high fat diet-induced insulin resistance in mice
Xiruo Li, Dong-Yan Zhang, D. Vatner, L. Goedeke +4 more
2020Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
Semantic Scholar
Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport
A. Vijayakumar, Pratik Aryal, Jennifer Wen, I. Syed +10 more
2017Cell Reports127 citations Open access
Semantic Scholar
SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia
Ali R. Nasiri, Marcos R Rodrigues, Zong-Yu Li, Brooks P. Leitner +1 more
2019Cancer & Metabolism101 citations Open access
Semantic Scholar
Sodium-glucose cotransporter-2 inhibitors: Understanding the mechanisms for therapeutic promise and persisting risks
Rachel J. Perry, G. Shulman
2020Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Mechanisms by which a very low calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
Rachel J. Perry, Liang Peng, G. Cline, Yong-Liang Wang +8 more
2017Cell Metabolism91 citations Open access
Semantic Scholar
Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats
Rachel J. Perry, Aviva Rabin-Court, Joongyu D. Song, R. Cardone +3 more
2019Nature Communications87 citations Open access
Semantic Scholar
Leptin’s hunger-suppressing effects are mediated by the hypothalamic–pituitary–adrenocortical axis in rodents
Rachel J. Perry, J. Resch, Amelia M. Douglass, Joseph C. Madara +6 more
2019Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
Semantic Scholar
Diabetes medications and risk of HCC
M. C. Plaz Torres, Ariel Jaffe, Rachel J. Perry, E. Marabotto +2 more
2022Hepatology80 citations Open access
Semantic Scholar
Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes
L. Goedeke, Rachel J. Perry, G. Shulman
2019Annual Review of Pharmacology and Toxicology79 citations Open access
Semantic Scholar
Origin and Function of Stress-Induced IL-6 in Murine Models
H. Qing, R. Desrouleaux, Kavita Israni-Winger, Y. Mineur +8 more
2020Cell76 citations Open access
Semantic Scholar
Metabolic control analysis of hepatic glycogen synthesis in vivo
Y. Nozaki, Max C. Petersen, Dong-Yan Zhang, D. Vatner +11 more
2020Proceedings of the National Academy of Sciences of the United States of America75 citations Open access
Semantic Scholar
A microRNA linking human positive selection and metabolic disorders
Li-Feng Wang, N. Sinnott-Armstrong, Alexandre Wagschal, A. Wark +28 more
2020Cell74 citations Open access
Semantic Scholar
OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance
Yunfan Yang, Xiruo Li, Harding H. Luan, Bichen Zhang +17 more
2020Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms
G. Ferrandino, R. Kaspari, O. Spadaro, A. Reyna-Neyra +6 more
2017Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Mechanistic Links between Obesity, Insulin, and Cancer
Rachel J. Perry, G. Shulman
2020Trends in Cancer62 citations Open access
Semantic Scholar
Insulin and cancer: a tangled web
Brooks P. Leitner, S. Siebel, Ngozi D. Akingbesote, Xinyi Zhang +1 more
2022Biochemical Journal58 citations Open access
Semantic Scholar
Mechanism for leptin’s acute insulin-independent effect to reverse diabetic ketoacidosis
Rachel J. Perry, Liang Peng, Abudukadier Abulizi, L. Kennedy +2 more
2017Journal of Clinical Investigation58 citations Open access
Semantic Scholar
Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer
Yong-Liang Wang, Ali R. Nasiri, William E. Damsky, Curtis J. Perry +5 more
2018Cell Reports52 citations Open access
Semantic Scholar
Controlled-Release Mitochondrial Protonophore (CRMP) Reverses Dyslipidemia and Hepatic Steatosis in Dysmetabolic Nonhuman Primates
L. Goedeke, Liang Peng, Valle Montalvo-Romeral, G. Butrico +8 more
2019Science Translational Medicine51 citations Open access
Semantic Scholar
Brown adipose TRX2 deficiency activates mtDNA-NLRP3 to impair thermogenesis and protect against diet-induced insulin resistance
Yan-Rui Huang, J. H. Zhou, Hai-Feng Zhang, A. Canfrán-Duque +5 more
2022Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Short-term overnutrition induces white adipose tissue insulin resistance through sn-1,2-diacylglycerol/PKCε/insulin receptor Thr1160 phosphorylation
Kun Lyu, Dong-Yan Zhang, Joongyu D. Song, Xiruo Li +3 more
2021JCI Insight43 citations Open access
Semantic Scholar
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis
Rachel J. Perry, Dongyan Zhang, Allison L. Brill, L. Goedeke +4 more
2020Nature42 citations Open access
Semantic Scholar
Imeglimin – Current Development and Future Potential in Type 2 Diabetes
Chigoziri Konkwo, Rachel J. Perry
2020Drugs39 citations Open access
Semantic Scholar
A controlled‐release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice
Abudukadier Abulizi, Rachel J. Perry, J. Camporez, M. Jurczak +3 more
2017The FASEB Journal37 citations Open access
Semantic Scholar
A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
M. Han, Rachel J. Perry, J. Camporez, P. Scherer +3 more
2020Genes & Development35 citations Open access
Semantic Scholar
A Non-Invasive Method to Assess Hepatic Acetyl-CoA in Vivo
Rachel J. Perry, Liang Peng, G. Cline, K. Petersen +1 more
2017Cell Metabolism35 citations Open access
Semantic Scholar
Dissociation of muscle insulin resistance from alterations in mitochondrial substrate preference
Joongyu D. Song, T. Alves, D. Befroy, Rachel J. Perry +9 more
2020Cell Metabolism34 citations Open access
Semantic Scholar
Leptin mediates postprandial increases in body temperature through hypothalamus-adrenal medulla-adipose tissue crosstalk.
Rachel J. Perry, Kun Lyu, Aviva Rabin-Court, Jianying Dong +6 more
2020Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Defective fatty acid oxidation in mice with muscle-specific acyl-CoA synthetase 1 deficiency increases amino acid use and impairs muscle function
Liyang Zhao, F. Pascual, Lawrence G. Bacudio, A. L. Suchanek +8 more
2019Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation
Aviva Rabin-Court, Marcos R Rodrigues, Xian-Man Zhang, Rachel J. Perry
2019PLoS ONE23 citations Open access
Semantic Scholar
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice
R. C. Gaspar, Kun Lyu, Brandon T. Hubbard, Brooks P. Leitner +11 more
2022Diabetologia20 citations Open access
Semantic Scholar
Multimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma
Brooks P. Leitner, K. Givechian, Shyryn Ospanova, Aray Beisenbayeva +2 more
2022npj Precision Oncology19 citations Open access
Semantic Scholar
Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance
T. Schumann, Jörg König, C. von Loeffelholz, D. Vatner +15 more
2021Communications Biology19 citations Open access
Semantic Scholar
A precision medicine approach to metabolic therapy for breast cancer in mice
Ngozi D. Akingbesote, Aaron D. Norman, Wanling Zhu, Alexandra A. Halberstam +4 more
2021Communications Biology19 citations Open access
Semantic Scholar
Current mechanisms in obesity and tumor progression
Andin Fosam, Rachel J. Perry
2020Current opinion in clinical nutrition and metabolic care19 citations Open access
Semantic Scholar
An optimized method for tissue glycogen quantification
Kyle J. Schaubroeck, Brooks P. Leitner, Rachel J. Perry
2022Physiological Reports18 citations Open access
Semantic Scholar
Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1.
Rachel J. Perry
2022Diabetes17 citations Open access
Semantic Scholar
Tissue-specific reprogramming of glutamine metabolism maintains tolerance to sepsis
Brooks P. Leitner, W. Lee, Wanling Zhu, Xinyi Zhang +4 more
2023PLoS ONE16 citations Open access
Semantic Scholar

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