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Beatrice Griffiths · SciRah

Researcher profile · Semantic Scholar

Beatrice Griffiths

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Beatrice Griffiths — researcher profile on SciRah

h-index: 9
Works: 23
Citations: 701

Most-cited papers

Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
A. Woolston, K. Khan, G. Spain, L. Barber +35 more
2018bioRxiv235 citations Open access
Semantic Scholar
Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment
Alice Newey, Beatrice Griffiths, Justine Michaux, Song-Pak Hui +16 more
2019Journal of Immunotherapy for Cancer131 citations Open access
Semantic Scholar
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids
R. Gonzalez-Exposito, Maria Semiannikova, Beatrice Griffiths, K. Khan +24 more
2019Journal of Immunotherapy for Cancer112 citations Open access
Semantic Scholar
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer
K. von Loga, A. Woolston, M. Punta, L. Barber +11 more
2019Nature Communications67 citations Open access
Semantic Scholar
Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumor DNA sequencing
S. Mansukhani, L. Barber, D. Kleftogiannis, S. Moorcraft +26 more
2018Clinical Chemistry54 citations Open access
Semantic Scholar
Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer
A. Woolston, L. Barber, Beatrice Griffiths, O. Pich +8 more
2021Nature Ecology & Evolution28 citations Open access
Semantic Scholar
Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes
Benjamin R. Challoner, K. von Loga, A. Woolston, Beatrice Griffiths +12 more
2020Journal of the National Cancer Institute23 citations Open access
Semantic Scholar
Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma
M. Davidson, L. Barber, A. Woolston, C. Cafferkey +13 more
2019Cancers21 citations Open access
Semantic Scholar
Multiplexed single cell protein expression analysis in solid tumours using a miniaturised microfluidic assay
A. Magness, J. Squires, Beatrice Griffiths, K. Khan +5 more
2017Convergent Science Physical Oncology15 citations Open access
Semantic Scholar
Circulating Tumour DNA Sequencing Identifies a Genetic Resistance-Gap in Colorectal Cancers with Acquired Resistance to EGFR-Antibodies and Chemotherapy
F. Knebel, L. Barber, Alice Newey, D. Kleftogiannis +12 more
2020Cancers6 citations Open access
Semantic Scholar
CEA expression patterns determine response and resistance to the CEA-TCB bispecific immunotherapy antibody in colorectal cancer patient derived organoids.
Reyes Gonzalez Exposito, Maria Semmianikova, Beatrice Griffiths, K. Khan +16 more
2019Journal of Clinical Oncology3 citations
Semantic Scholar
Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation Within Clinical Trial Data
K. Khan, R. Gonzalez-Exposito, D. Cunningham, D. Koh +19 more
2020Frontiers in Oncology2 citations Open access
Semantic Scholar
Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumour DNA sequencing
S. Mansukhani, L. Barber, S. Moorcraft, M. Davidson +23 more
2017bioRxiv2 citations Open access
Semantic Scholar
Diagnostic accuracy and safety of coaxial core-needle biopsy (CNB) system in Oncology patients treated in a specialist cancer centre with prospective validation within clinical trial data
K. Khan, Reyes Gonzalez-Exposito, David Cunningham, Dow-Mu Koh +19 more
2020medRxiv1 citations Open access
Semantic Scholar
Author Correction: Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer
K. von Loga, A. Woolston, M. Punta, L. Barber +11 more
2020Nature Communications1 citations Open access
Semantic Scholar
Abstract 4339: Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial
K. Khan, A. Woolston, G. Spain, L. Barber +25 more
2018Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Mutational processes impact the evolution of anti-EGFR antibody resistance in colorectal cancer
A. Woolston, L. Barber, Beatrice Griffiths, N. Matthews +6 more
2020bioRxiv0 citations Open access
Semantic Scholar
Multispectral immunofluorescence and computational imaging analysis define the prognostic role of T-cell infiltrates in gastric cancer
Benjamin R. Challoner, K. von Loga, A. Woolston, Beatrice Griffiths +7 more
20190 citations Open access
Semantic Scholar
Perioperative FLOT + anti-PD-L1 avelumab (FLOT-A) chemo-immunotherapy in resectable oesophagogastric adenocarcinoma (OGA): Safety and biomarker data from the ICONIC trial safety run-in
M. Davidson, S. Mansukhani, N. Starling, I. Chau +16 more
2019Annals of Oncology0 citations Open access
Semantic Scholar
Ultra-sensitive mutation detection and genome-wide DNA copy 11 number reconstruction by error corrected circulating tumor DNA 12 sequencing 13 14
S. Mansukhani, L. Barber, D. Kleftogiannis, Si Yu +29 more
20180 citations
Semantic Scholar
Abstract 422: Lymph node metastasis evolution drives immune evasion and targeted therapy resistance in gastro-esophageal adenocarcinomas (GEAs)
M. Davies, L. Barber, G. Spain, F. Lopes +16 more
20170 citations
Semantic Scholar
Intratumor heterogeneity of DNA copy number aberrations in gastric and oesophageal adenocarcinomas.
M. Davies, D. Alpár, Beatrice Griffiths, L. Barber +7 more
20150 citations
Semantic Scholar
Assay sensitivity and specificity
S. Mansukhani, L. Barber, D. Kleftogiannis, S. Moorcraft +27 more
0 citations
Semantic Scholar

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