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A. Skowera · SciRah

Researcher profile · Semantic Scholar

A. Skowera

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A. Skowera — researcher profile on SciRah

h-index: 25
Works: 46
Citations: 3,265

Most-cited papers

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides
L. Wooldridge, J. Ekeruche-Makinde, H. A. van den Berg, A. Skowera +8 more
2011Journal of Biological Chemistry467 citations Open access
Semantic Scholar
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.
A. Skowera, R. Ellis, R. Varela-Calviño, S. Arif +14 more
2008Journal of Clinical Investigation431 citations Open access
Semantic Scholar
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
D. Cole, A. Bulek, G. Dolton, Andrea J. Schauenberg +13 more
2016Journal of Clinical Investigation282 citations Open access
Semantic Scholar
Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation
Chung-Ching Chu, N. Ali, P. Karagiannis, P. Di Meglio +9 more
2012Journal of Experimental Medicine272 citations Open access
Semantic Scholar
Structural basis of human β-cell killing by CD8+ T cells in Type 1 diabetes
A. Bulek, D. Cole, A. Skowera, G. Dolton +17 more
2012Nature Immunology157 citations Open access
Semantic Scholar
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T-cell recognition
D. Cole, E. Edwards, Katherine K. Wynn, M. Clement +10 more
2010Journal of Immunology145 citations Open access
Semantic Scholar
High levels of type 2 cytokine‐producing cells in chronic fatigue syndrome
A. Skowera, A. Cleare, Dorothy Blair, L. Bevis +2 more
2004Clinical and Experimental Immunology133 citations Open access
Semantic Scholar
Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells
Deborah Kronenberg, R. Knight, Megan Estorninho, R. Ellis +9 more
2012Diabetes121 citations Open access
Semantic Scholar
β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure
A. Skowera, K. Ladell, J. E. McLaren, G. Dolton +13 more
2014Diabetes119 citations Open access
Semantic Scholar
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
J. Ekeruche-Makinde, John J. Miles, H. A. van den Berg, A. Skowera +19 more
2013Blood111 citations Open access
Semantic Scholar
Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture
J. S. Allen, K. Pang, A. Skowera, R. Ellis +7 more
2009Diabetes110 citations Open access
Semantic Scholar
Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression
T. Tree, J. Lawson, H. Edwards, A. Skowera +3 more
2010Diabetes107 citations Open access
Semantic Scholar
Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology
Hyong Jin Cho, A. Skowera, A. Cleare, S. Wessely
2006Current Opinion in Psychiatry99 citations
Semantic Scholar
Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
G. Dolton, A. Lissina, A. Skowera, K. Ladell +13 more
2014Clinical and Experimental Immunology87 citations Open access
Semantic Scholar
Predictors of fatigue following the onset of infectious mononucleosis
B. Candy, T. Chalder, A. Cleare, A. Peakman +5 more
2003Psychological Medicine84 citations Open access
Semantic Scholar
Cellular Immune Activation in Gulf War Veterans
A. Skowera, M. Hotopf, E. Sawicka, R. Varela-Calviño +7 more
2004Journal of Clinical Immunology77 citations
Semantic Scholar
Clinical-Grade Multipotent Adult Progenitor Cells Durably Control Pathogenic T Cell Responses in Human Models of Transplantation and Autoimmunity
J. Reading, Jen-Nie H. M. Yang, Shereen Sabbah, A. Skowera +9 more
2013Journal of Immunology70 citations Open access
Semantic Scholar
Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity
R. Knight, Deborah Kronenberg, Min Zhao, Guo C. Huang +7 more
2012Diabetes65 citations Open access
Semantic Scholar
Autoreactive T effector memory differentiation mirrors &bgr; cell function in type 1 diabetes
L. Yeo, A. Woodwyk, S. Sood, A. Lorenc +12 more
2018Journal of Clinical Investigation64 citations Open access
Semantic Scholar
Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
Jonathan Chee, Hyun-Ja Ko, A. Skowera, G. Jhala +8 more
2014Journal of Immunology60 citations Open access
Semantic Scholar
Immunological dysfunction, vaccination and Gulf War illness
M. Peakman, A. Skowera, M. Hotopf
2006Philosophical Transactions of the Royal Society B: Biological Sciences34 citations Open access
Semantic Scholar
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies
M. Clement, J. Pearson, S. Gras, H. A. van den Berg +15 more
2016Scientific Reports32 citations Open access
Semantic Scholar
Identification of a Naturally Processed Cytotoxic CD8 T-Cell Epitope of Coxsackievirus B4, Presented by HLA-A2.1 and Located in the PEVKEK Region of the P2C Nonstructural Protein
R. Varela-Calviño, A. Skowera, S. Arif, M. Peakman
2004Journal of Virology31 citations Open access
Semantic Scholar
Long-lasting T cell responses to biological warfare vaccines in human vaccinees.
J. S. Allen, A. Skowera, G. Rubin, S. Wessely +1 more
2006Clinical Infectious Diseases26 citations Open access
Semantic Scholar
Antinuclear autoantibodies (ANA) in Gulf War‐related illness and chronic fatigue syndrome (CFS) patients
A. Skowera, E. Stewart, E. Davis, A. Cleare +6 more
2002Clinical and Experimental Immunology25 citations Open access
Semantic Scholar
Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop
E. James, J. R. Abreu, John W. McGinty, J. Odegard +16 more
2018Diabetologia20 citations Open access
Semantic Scholar
A distinct immunogenic region of glutamic acid decarboxylase 65 is naturally processed and presented by human islet cells to cytotoxic CD8 T cells
R. Knight, G. Dolton, D. Kronenberg-Versteeg, M. Eichmann +7 more
2015Clinical and Experimental Immunology16 citations Open access
Semantic Scholar
Analysis of Anthrax and Plague Biowarfare Vaccine Interactions with Human Monocyte-Derived Dendritic Cells1
A. Skowera, Esther C. de Jong, J. Schuitemaker, J. S. Allen +4 more
2005Journal of Immunology13 citations Open access
Semantic Scholar
Naturally arising human CD 4 T cells that recognize islet autoantigens and secrete IL-10 regulate pro-inflammatory T cell responses via linked suppression
T. Tree, J. Lawson, H. Edwards, A. Skowera +4 more
20105 citations
Semantic Scholar
engagement Peptide length determines the outcome of TCR/peptide-MHCI
L. Wooldridge, J. Rossjohn, M. Peakman, D. Price +14 more
20132 citations
Semantic Scholar
Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation
L. Wooldridge, David J. Morgan, J. Pearson, S. Gras +16 more
2017Journal of Immunology0 citations
Semantic Scholar
Running title : GAD 65 epitopes on β-cells
R. Knight, G. Dolton, D. Kronenberg-Versteeg, M. Eichmann +7 more
20140 citations
Semantic Scholar
Islet Pathology in Type 1 Effector-Memory T Cells Develop in Islets
W. Kay, B. Krishnamurthy, H. Thomas, A. Lew +8 more
20130 citations
Semantic Scholar
The length of the peptide in the MHC groove compartmentalizes the CD8+ T cell repertoire (P1186)
John J Miles, H. A. van den Berg, J. Ekeruche-Makinde, A. Skowera +10 more
2013Journal of Immunology0 citations
Semantic Scholar
Peptide length determines the outcome of T cell receptor / peptide-MHCI
J. Ekeruche-Makinde, John J Miles, Hugo A. van den Berg, A. Skowera +22 more
20120 citations
Semantic Scholar
Monocyte-Derived Dendritic Cells Vaccine Interactions with Human Analysis of Anthrax and Plague Biowarfare
M. Kapsenberg, M. Peakman, J. S. Allen, S. Wessely +4 more
20110 citations
Semantic Scholar
Direct ex vivo Enumeration of CD8 T Cells Specific for β-cell Autoantigens by Peptide-HLA Multimers in Type 1 Diabetes
A. Skowera, S. Arif, A. Zaremba, C. Dayan +3 more
20100 citations
Semantic Scholar
Phenotypic and functional characterization of a novel subset of skin-resident regulatory CD141(+) DCs that spontaneously produce high levels of IL-10
Chung-Ching Chu, P. Di Meglio, A. Skowera, N. Ali +5 more
20100 citations
Semantic Scholar
T.125. Identifying Heteroclitic Peptides that Mimic the Major CTL Target on Preproinsulin in Type 1 Diabetes
A. Skowera, John J Miles, L. Wooldridge, D. Cole +4 more
20090 citations
Semantic Scholar
OR.62. Glucose-regulated Cytotoxic T Cell Epitope of Preproinsulin Targets Killing of Beta-cells in Type 1 Diabetes
A. Skowera, R. Ellis, Min Zhao, Guo C. Huang +1 more
20080 citations
Semantic Scholar
Islet-specific regulatory T-cells provide tissue-specific suppression of autoimmune responses through APC killing
T. Tree, J. Lawson, H. Edwards, A. Skowera +3 more
20070 citations
Semantic Scholar
Cytotoxic preproinsulin-specific CD8 T cells in type 1 diabetes in man
A. Skowera, R. Ellis, T. Tree, M. Peakman +1 more
20070 citations
Semantic Scholar
Immune activation and vaccine effects in post-combat illnesses.
A. Skowera
20070 citations
Semantic Scholar
Detection of autoreactive CD8 T-CELLS using MHC class I tetramers loaded with islet autoantigenic peptides in patients with type I diabetes
S. Arif, A. Skowera, Hina Shariff, C. Dayan +4 more
20070 citations
Semantic Scholar
Identification of a naturally presented CD8 T cell epitope from the signal peptide of prepro-insulin which may be generated by intra-membrane proteases
R. Ellis, R. Varela-Calviño, A. Skowera, C. H. Van Krinks +1 more
20070 citations
Semantic Scholar
[Treatment of wounds of the cervix uteri after coagulation, with a note on the use of organic glass].
E. Midak, A. Skowera
1965Wiadomosci lekarskie0 citations
Semantic Scholar

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