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K. Ladell · SciRah

Researcher profile · Semantic Scholar

K. Ladell

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K. Ladell — researcher profile on SciRah

h-index: 48
Works: 189
Citations: 7,929

Most-cited papers

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity
M. Shugay, D. Bagaev, I. Zvyagin, R. Vroomans +24 more
2017Nucleic Acids Res.576 citations Open access
Semantic Scholar
Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
Martin S. Davey, Carrie R. Willcox, S. P. Joyce, K. Ladell +8 more
2017Nature Communications263 citations Open access
Semantic Scholar
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans
G. Galletti, G. De Simone, E. Mazza, S. Puccio +28 more
2020Nature Immunology255 citations Open access
Semantic Scholar
Islet-reactive CD8+ T-cell frequencies in the pancreas but not blood distinguish type 1 diabetes from healthy donors
Slobodan Culina, A. Lalanne, G. Afonso, K. Cerosaletti +24 more
2018Science immunology227 citations Open access
Semantic Scholar
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2
Mikhail Goncharov, Dmitry V. Bagaev, Dmitrii S. Shcherbinin, I. Zvyagin +22 more
2022Nature Methods207 citations Open access
Semantic Scholar
Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia.
S. Anguille, A. Van de Velde, E. Smits, V. V. Van Tendeloo +27 more
2017Blood206 citations Open access
Semantic Scholar
Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease
Toufic Mayassi, K. Ladell, Herman Gudjonson, J. E. McLaren +23 more
2019Cell168 citations Open access
Semantic Scholar
Memory CD4+ T cells are generated in the human fetal intestine
Na Li, V. van Unen, T. Abdelaal, Nan-Nan Guo +14 more
2019Nature Immunology139 citations Open access
Semantic Scholar
CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells
Elena Brenna, A. Davydov, K. Ladell, J. E. McLaren +10 more
2020Cell Reports103 citations Open access
Semantic Scholar
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis
E. Wong, Marielle C. Gold, Erin W. Meermeier, B. Xulu +24 more
2019Communications Biology102 citations Open access
Semantic Scholar
The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytomegalovirus
I. Murrell, C. Bedford, K. Ladell, K. Miners +4 more
2017Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux
Raya Ahmed, L. Roger, Pedro Costa del Amo, K. Miners +11 more
2016Cell Reports85 citations Open access
Semantic Scholar
CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin
M. McCully, K. Ladell, R. Andrews, Rhiannon E. Jones +9 more
2018Journal of Immunology82 citations Open access
Semantic Scholar
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies
C. Fielding, P. Sabberwal, J. Williamson, Edward J. D. Greenwood +17 more
2022eLife64 citations Open access
Semantic Scholar
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids
Wun S. Kwok, J. F. Reijneveld, T. Cheng, K. Ladell +24 more
2018Nature Immunology63 citations Open access
Semantic Scholar
Inhibitory killer-cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV and HTLV-1
L. Boelen, Bisrat J. Debebe, M. Silveira, Arafa Salam +25 more
2018Science immunology60 citations Open access
Semantic Scholar
Clonal selection in the human V delta 1 T cell repertoire indicates gamma delta TCR-dependent adaptive immune surveillance
Davey, Carrie R. Willcox, S. P. Joyce, K. Ladell +8 more
201760 citations
Semantic Scholar
Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells
Benjamin J Meckiff, K. Ladell, J. E. McLaren, Gordon B Ryan +4 more
2019Journal of Immunology52 citations Open access
Semantic Scholar
Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID.
Kirsten Baillie, Helen E. Davies, Sam Keat, K. Ladell +7 more
2024i Medicina51 citations Open access
Semantic Scholar
Exploring the pre-immune landscape of antigen-specific T cells
M. Pogorelyy, A. D. Fedorova, J. E. McLaren, K. Ladell +8 more
2018Genome Medicine48 citations Open access
Semantic Scholar
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus
Virginia-Maria Vlahava, I. Murrell, Lihui Zhuang, Rebecca J. Aicheler +11 more
2021Journal of Clinical Investigation42 citations Open access
Semantic Scholar
CD57+ Memory T Cells Proliferate In Vivo
Raya Ahmed, K. Miners, Julio Lahoz-Beneytez, Rhiannon E. Jones +11 more
2020Cell Reports42 citations Open access
Semantic Scholar
Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness
Pedro Costa Del Amo, Julio Lahoz-Beneytez, L. Boelen, Raya Ahmed +11 more
2018PLoS Biology39 citations Open access
Semantic Scholar
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans
S. Edwards, Caroline E. Sutton, K. Ladell, E. Grant +23 more
2020Journal of Experimental Medicine38 citations Open access
Semantic Scholar
Human T cell dynamics in vivo are compatible with long-lived immunological memory and stemness
Pedro Costa del Amo, Julio Lahoz Beneytez, L. Boelen, Raya Ahmed +10 more
201833 citations
Semantic Scholar
Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype
S. Hanna, Wendy E. Powell, Anna E. Long, E. Robinson +10 more
2020Diabetologia30 citations Open access
Semantic Scholar
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells
F. Pearson, K. Tullett, Ingrid M. Leal-Rojas, O. Haigh +13 more
2020Clinical & Translational Immunology29 citations Open access
Semantic Scholar
Stochastic expansions maintain the clonal stability of CD8+ T cell populations undergoing memory inflation driven by MCMV
Corinne J. Smith, V. Venturi, Maire F. Quigley, Holly Turula +13 more
2019Journal of Immunology27 citations Open access
Semantic Scholar
IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
J. E. McLaren, M. Clement, M. Marsden, K. Miners +11 more
2019Journal of Immunology27 citations Open access
Semantic Scholar
HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection
V. Du, A. Bansal, J. Carlson, J. Salazar-Gonzalez +9 more
2016Journal of Immunology27 citations Open access
Semantic Scholar
Germline bias dictates cross-serotype reactivity in a common
A. Culshaw, K. Ladell, S. Gras, J. E. McLaren +13 more
202026 citations
Semantic Scholar
Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs
S. A. Kasatskaya, K. Ladell, E. Egorov, K. Miners +11 more
2020eLife26 citations Open access
Semantic Scholar
Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry
John J Miles, Mai Tan, G. Dolton, E. Edwards +23 more
2018Journal of Clinical Investigation26 citations Open access
Semantic Scholar
A T cell receptor locus encodes a malaria-specific immune response gene
Natalija Van Braeckel-Budimir, S. Gras, K. Ladell, T. M. Josephs +7 more
2017Immunity26 citations Open access
Semantic Scholar
The MAIT TCRβ chain contributes to discrimination of microbial ligand
G. Narayanan, J. E. McLaren, Erin W. Meermeier, K. Ladell +7 more
2020Immunology and Cell Biology24 citations Open access
Semantic Scholar
Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1
H. Watson, G. Dolton, J. Ohme, K. Ladell +9 more
2016Immunology and Cell Biology22 citations Open access
Semantic Scholar
ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells
Rebar N. Mohammed, Sophie C. Wehenkel, E. Galkina, Emma-Kate Yates +18 more
2019Scientific Reports21 citations Open access
Semantic Scholar
Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop
E. James, J. R. Abreu, John W. McGinty, J. Odegard +16 more
2018Diabetologia20 citations Open access
Semantic Scholar
Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes
Wendy Powell, Stephanie J. Hanna, Claire N. Hocter, E. Robinson +9 more
2018Diabetologia18 citations Open access
Semantic Scholar
Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response
A. Culshaw, K. Ladell, S. Gras, J. E. McLaren +16 more
2017Nature Immunology18 citations
Semantic Scholar
Group A streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation
Yi-Ling Chen, J. Ng, R. Babu, J. Woo +13 more
2023Science immunology16 citations Open access
Semantic Scholar
SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues.
C. Starke, Carol L. Vinton, K. Ladell, J. E. McLaren +10 more
2020Journal of Clinical Investigation16 citations Open access
Semantic Scholar
A Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1
S. Caucheteux, J. P. Mitchell, M. Ivory, Sachiko Hirosue +16 more
201615 citations
Semantic Scholar
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways
A. Rubina, Mihil Patel, K. Nightingale, M. Potts +18 more
2023Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4+ memory T cells
F. Shepherd, Kate Davies, K. Miners, S. Llewellyn-Lacey +6 more
2023Communications Biology13 citations Open access
Semantic Scholar
Sepsis shapes the human γδ TCR repertoire in an age‐ and pathogen‐dependent manner
E. Giannoni, Guillem Sanchez Sanchez, Isoline Verdebout, M. Papadopoulou +11 more
2024European Journal of Immunology11 citations Open access
Semantic Scholar
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor
M. Clement, L. Knezevic, Tamsin Dockree, J. E. McLaren +11 more
2020Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1
M. Clement, K. Ladell, K. Miners, M. Marsden +13 more
2023eLife10 citations Open access
Semantic Scholar
CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Lisa Ciacchi, M. V. D. van de Garde, K. Ladell, C. Farenc +8 more
2023Immunity10 citations Open access
Semantic Scholar
ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies
C. Fielding, P. Sabberwal, J. Williamson, Ejd Greenwood +17 more
2021bioRxiv10 citations Open access
Semantic Scholar

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