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N. Margaryan · SciRah

Researcher profile · Semantic Scholar

N. Margaryan

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N. Margaryan — researcher profile on SciRah

h-index: 31
Works: 73
Citations: 3,608

Most-cited papers

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness
Jolanta M. Topczewska, Lynne-Marie Postovit, N. Margaryan, Anthony Sam +5 more
2006Nature Medicine445 citations
Semantic Scholar
Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells
Lynne-Marie Postovit, N. Margaryan, E. Seftor, D. Kirschmann +5 more
2008Proceedings of the National Academy of Sciences of the United States of America294 citations Open access
Semantic Scholar
Tumor cell vasculogenic mimicry: from controversy to therapeutic promise.
R. Seftor, Angela R. Hess, E. Seftor, D. Kirschmann +3 more
2012American Journal of Pathology279 citations Open access
Semantic Scholar
Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment.
P. Kulesa, Jennifer C. Kasemeier-Kulesa, Jessica M. Teddy, N. Margaryan +3 more
2006Proceedings of the National Academy of Sciences of the United States of America256 citations
Semantic Scholar
Focal adhesion kinase promotes the aggressive melanoma phenotype.
Angela R. Hess, Lynne-Marie Postovit, N. Margaryan, E. Seftor +4 more
2005Cancer Research154 citations Open access
Semantic Scholar
Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry.
W. Ruf, E. Seftor, R. Petrovan, R. Weiss +5 more
2003Cancer Research139 citations
Semantic Scholar
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas.
Jian-Zhong Qin, L. Stennett, P. Bacon, Barbara K. Bodner +10 more
2004Molecular Cancer Therapeutics134 citations
Semantic Scholar
Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype
Katharine M. Hardy, D. Kirschmann, E. Seftor, N. Margaryan +3 more
2010Cancer Research123 citations Open access
Semantic Scholar
Reactivation of Embryonic Nodal Signaling is Associated with Tumor Progression and Promotes the Growth of Prostate Cancer Cells
Mitchell G. Lawrence, N. Margaryan, D. Loessner, A. Collins +9 more
2011The Prostate104 citations Open access
Semantic Scholar
Deciphering the signaling events that promote melanoma tumor cell vasculogenic mimicry and their link to embryonic vasculogenesis: Role of the Eph receptors
Angela R. Hess, N. Margaryan, E. Seftor, M. Hendrix
2007Developmental Dynamics97 citations
Semantic Scholar
Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase‐facilitated breast cancer migration
Lynne-Marie Postovit, Daniel E. Abbott, Stacey L. Payne, William W. Wheaton +6 more
2008Journal of Cellular Biochemistry91 citations
Semantic Scholar
Interferon Regulatory Factor 6 Promotes Cell Cycle Arrest and Is Regulated by the Proteasome in a Cell Cycle-Dependent Manner
C. Bailey, D. Abbott, N. Margaryan, Z. Khalkhali‐Ellis +1 more
2008Molecular and Cellular Biology90 citations Open access
Semantic Scholar
EphA2 as a promoter of melanoma tumorigenicity
N. Margaryan, L. Strizzi, Daniel E. Abbott, E. Seftor +3 more
2009Cancer Biology & Therapy83 citations Open access
Semantic Scholar
Mammary Serine Protease Inhibitor (Maspin) Binds Directly to Interferon Regulatory Factor 6
C. Bailey, Z. Khalkhali‐Ellis, S. Kondo, N. Margaryan +6 more
2005Journal of Biological Chemistry76 citations Open access
Semantic Scholar
Emerging Roles of Nodal and Cripto-1: From Embryogenesis to Breast Cancer Progression
L. Strizzi, Lynne-Marie Postovit, N. Margaryan, E. Seftor +4 more
2008Breast Disease74 citations Open access
Semantic Scholar
Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention
L. Strizzi, Lynne-Marie Postovit, N. Margaryan, A. Lipavsky +5 more
2009Expert Review of Dermatology72 citations Open access
Semantic Scholar
Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer
L. Strizzi, Katharine M. Hardy, N. Margaryan, D. Hillman +8 more
2012Breast Cancer Research71 citations Open access
Semantic Scholar
Cripto-1 Is a Cell Surface Marker for a Tumorigenic, Undifferentiated Subpopulation in Human Embryonal Carcinoma Cells
Kazuhide Watanabe, Matthew J. Meyer, L. Strizzi, Joseph M. Lee +8 more
2010Stem Cells68 citations Open access
Semantic Scholar
A Requirement for Dimerization of HP1Hsα in Suppression of Breast Cancer Invasion*
L. E. Norwood, Timothy J. Moss, N. Margaryan, Sarah L. Cook +5 more
2006Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Role of nodal signaling and the microenvironment underlying melanoma plasticity
Lynne-Marie Postovit, N. Margaryan, E. Seftor, M. Hendrix
2008Pigment Cell & Melanoma Research58 citations
Semantic Scholar
LPA signaling is regulated through the primary cilium: a novel target in glioblastoma
Yuriy V. Loskutov, C. Griffin, Kristina M. Marinak, A. Bobko +4 more
2018Oncogene56 citations Open access
Semantic Scholar
The Epigenetic Influence of Tumor and Embryonic Microenvironments: How Different are They?
D. Abbott, C. Bailey, Lynne-Marie Postovit, E. Seftor +3 more
2008Cancer Microenvironment53 citations Open access
Semantic Scholar
Reevaluating cathepsin D as a biomarker for breast cancer serum activity levels versus histopathology
D. Abbott, N. Margaryan, J. Jeruss, S. Khan +6 more
2010Cancer Biology & Therapy51 citations Open access
Semantic Scholar
Nodal signaling promotes a tumorigenic phenotype in human breast cancer
Gina T. Kirsammer, L. Strizzi, N. Margaryan, Alina Gilgur +5 more
2014Seminars in Cancer Biology49 citations Open access
Semantic Scholar
Expression and functional role of CRIPTO-1 in cutaneous melanoma
A. De Luca, Luana Lamura, L. Strizzi, C. Roma +9 more
2011British Journal of Cancer44 citations Open access
Semantic Scholar
Melanoma Tumor Cell Heterogeneity: A Molecular Approach to Study Subpopulations Expressing the Embryonic Morphogen Nodal
E. Seftor, R. E. Seftor, Don S. Weldon, Gina T. Kirsammer +3 more
2014Seminars in Oncology40 citations Open access
Semantic Scholar
The epigenetic reprogramming of poorly aggressive melanoma cells by a metastatic microenvironment
E. Seftor, P. Meltzer, Dawn A. Kirschmann, N. Margaryan +2 more
2006Journal of Cellular and Molecular Medicine40 citations Open access
Semantic Scholar
Cleavage of Histone 3 by Cathepsin D in the Involuting Mammary Gland
Z. Khalkhali‐Ellis, W. Goossens, N. Margaryan, M. Hendrix
2014PLoS ONE39 citations Open access
Semantic Scholar
A Novel Central Pathway Links Arterial Baroreceptors and Pontine Parasympathetic Neurons in Cerebrovascular Control
Khristofor Agassandian, V. Fazan, N. Margaryan, D. Dragon +2 more
2003Cellular and molecular neurobiology33 citations
Semantic Scholar
IFN-γ Regulation of Vacuolar pH, Cathepsin D Processing and Autophagy in Mammary Epithelial Cells
Z. Khalkhali‐Ellis, Daniel E. Abbott, C. Bailey, W. Goossens +4 more
2008Journal of Cellular Biochemistry32 citations Open access
Semantic Scholar
New insights into cathepsin D in mammary tissue development and remodeling
N. Margaryan, D. Kirschmann, A. Lipavsky, C. Bailey +2 more
2010Cancer Biology & Therapy31 citations Open access
Semantic Scholar
Age-Dependent Association between Protein Expression of the Embryonic Stem Cell Marker Cripto-1 and Survival of Glioblastoma Patients.
B. B. Tysnes, H. A. Sætran, S. Mørk, N. Margaryan +4 more
2013Translational Oncology30 citations Open access
Semantic Scholar
Temporal and spatial expression patterns for the tumor suppressor Maspin and its binding partner interferon regulatory factor 6 during breast development
C. Bailey, N. Margaryan, Daniel E. Abbott, B. C. Schutte +3 more
2009Development, Growth and Differentiation30 citations Open access
Semantic Scholar
Effects of a novel Nodal-targeting monoclonal antibody in melanoma
L. Strizzi, A. Sandomenico, N. Margaryan, Annalia Focà +11 more
2015OncoTarget29 citations Open access
Semantic Scholar
The significance of a Cripto-1-positive subpopulation of human melanoma cells exhibiting stem cell-like characteristics
L. Strizzi, N. Margaryan, Alina Gilgur, Katharine M. Hardy +3 more
2013Cell Cycle29 citations Open access
Semantic Scholar
Maspin regulates hypoxia-mediated stimulation of uPA/uPAR complex in invasive breast cancer cells
S. Amir, N. Margaryan, V. Odero-Marah, Z. Khalkhali‐Ellis +1 more
2005Cancer Biology & Therapy28 citations Open access
Semantic Scholar
Targeting Nodal in Conjunction with Dacarbazine Induces Synergistic Anti-cancer Effects in Metastatic Melanoma
Katharine M. Hardy, L. Strizzi, N. Margaryan, K. Gupta +3 more
2015Molecular Cancer Research26 citations Open access
Semantic Scholar
Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors
K. Whately, M. Voronkova, A. Maskey, Jasleen Gandhi +10 more
2021Oncogene22 citations Open access
Semantic Scholar
Targeting the Stem Cell Properties of Adult Breast Cancer Cells: Using Combinatorial Strategies to Overcome Drug Resistance
N. Margaryan, E. Seftor, R. Seftor, M. Hendrix
2017Current Molecular Biology Reports16 citations Open access
Semantic Scholar
Inorganic polyphosphate as an energy source in tumorigenesis
J. Boyineni, S. Sredni, N. Margaryan, L. Demirkhanyan +8 more
2020OncoTarget15 citations Open access
Semantic Scholar
The Stem Cell Phenotype of Aggressive Breast Cancer Cells
N. Margaryan, Hannah Hazard-Jenkins, M. Salkeni, M. Smolkin +5 more
2019Cancers15 citations Open access
Semantic Scholar
Targeting melanoma with front-line therapy does not abrogate Nodal-expressing tumor cells
M. Hendrix, I. Kandela, A. Mazar, E. Seftor +6 more
2017Laboratory Investigation15 citations Open access
Semantic Scholar
Exploiting the Convergence of Embryonic and Tumorigenic Signaling Pathways to Develop New Therapeutic Targets
D. Abbott, Lynne-Marie Postovit, E. Seftor, N. Margaryan +2 more
2007Stem Cell Reviews15 citations
Semantic Scholar
Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme.
Seema Jamil, J. Cedervall, Isabell Hultman, Rouknuddin Q. Ali +12 more
2013International Journal of Oncology13 citations Open access
Semantic Scholar
Translational significance of Nodal, Cripto-1 and Notch4 in adult nevi
L. Strizzi, N. Margaryan, P. Gerami, Zahra Haghighat +5 more
2016Oncology Letters11 citations Open access
Semantic Scholar
Nodal expression in triple-negative breast cancer: Cellular effects of its inhibition following doxorubicin treatment
Thomas M. Bodenstine, G. S. Chandler, D. W. Reed, N. Margaryan +7 more
2016Cell Cycle11 citations Open access
Semantic Scholar
Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors
S. Malchenko, S. Sredni, J. Boyineni, Y. Bi +8 more
2018OncoTarget10 citations Open access
Semantic Scholar
A Mouse Model of Human Primitive Neuroectodermal Tumors Resulting from Microenvironmentally-Driven Malignant Transformation of Orthotopically Transplanted Radial Glial Cells
S. Malchenko, S. Sredni, H. Hashimoto, Atsushi Kasai +10 more
2015PLoS ONE9 citations Open access
Semantic Scholar
Heterogeneity and Plasticity of Melanoma: Challenges of Current Therapies
M. Hendrix, E. Seftor, N. Margaryan, R. Seftor
20178 citations Open access
Semantic Scholar
Heterogeneity of Melanoma with Stem Cell Properties.
E. Seftor, N. Margaryan, R. Seftor, M. Hendrix
2019Advances in Experimental Medicine and Biology7 citations
Semantic Scholar

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Lynne-Marie Postovit

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