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L. Demirkhanyan · SciRah

Researcher profile · Semantic Scholar

L. Demirkhanyan

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L. Demirkhanyan — researcher profile on SciRah

h-index: 15
Works: 49
Citations: 894

Most-cited papers

The TRPM8 Protein Is a Testosterone Receptor
S. Asuthkar, P. Elustondo, L. Demirkhanyan, Xiaohui Sun +5 more
2014Journal of Biological Chemistry115 citations Open access
Semantic Scholar
Oxytocin modulates nociception as an agonist of pain-sensing TRPV1
Yelena Nersesyan, L. Demirkhanyan, Deny Cabezas-Bratesco, Victoria Oakes +11 more
2017Cell Reports114 citations Open access
Semantic Scholar
TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival
L. Mittermeier, L. Demirkhanyan, Benjamin Stadlbauer, A. Breit +8 more
2019Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
Structural basis of temperature sensation by the TRP channel TRPV3
A. Singh, L. McGoldrick, L. Demirkhanyan, Merfilius Leslie +2 more
2019Nature Structural & Molecular Biology103 citations Open access
Semantic Scholar
TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells
S. Asuthkar, K. Velpula, P. Elustondo, L. Demirkhanyan +1 more
2015OncoTarget80 citations Open access
Semantic Scholar
The TRPM8 Protein Is a Testosterone Receptor
S. Asuthkar, L. Demirkhanyan, Xiaohui Sun, P. Elustondo +6 more
2014Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Contribution of inorganic polyphosphate towards regulation of mitochondrial free calcium
M. E. Solesio, L. Demirkhanyan, E. Zakharian, E. Pavlov
2016Biochimica et Biophysica Acta58 citations Open access
Semantic Scholar
The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels
José Miguel Arcas, Alejandro González, K. Gers-Barlag, O. González-González +6 more
2018Journal of Neuroscience44 citations Open access
Semantic Scholar
The Multifaceted Role of miR-21 in Pancreatic Cancers
Clare Chen, L. Demirkhanyan, Christopher S Gondi
2024Cells41 citations Open access
Semantic Scholar
Stimulation‐dependent gating of TRPM3 channel in planar lipid bilayers
Kunitoshi Uchida, L. Demirkhanyan, S. Asuthkar, Alejandro M. Cohen +2 more
2016The FASEB Journal31 citations Open access
Semantic Scholar
Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii
L. McGoldrick, A. Singh, L. Demirkhanyan, Ting-Yu Lin +3 more
2019Nature Communications29 citations Open access
Semantic Scholar
The Role of Mucins in Cancer and Cancer Progression: A Comprehensive Review
Clare Chen, Ameena Patel, L. Demirkhanyan, Christopher S Gondi
2025Current Issues in Molecular Biology20 citations Open access
Semantic Scholar
High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer
S. Asuthkar, L. Demirkhanyan, Samuel R. Mueting, Alejandro M. Cohen +1 more
2016OncoTarget20 citations Open access
Semantic Scholar
Beyond Barriers: Achieving True Equity in Cancer Care
Zaphrirah Chin, Arshia Ghodrati, Milind Foulger, L. Demirkhanyan +1 more
2025Current Oncology16 citations Open access
Semantic Scholar
Inorganic polyphosphate as an energy source in tumorigenesis
J. Boyineni, S. Sredni, N. Margaryan, L. Demirkhanyan +8 more
2020OncoTarget15 citations Open access
Semantic Scholar
Circular dumbbell miR-34a-3p and −5p suppresses pancreatic tumor cell-induced angiogenesis and activates macrophages
M. Gnanamony, L. Demirkhanyan, L. Ge, Paresh M. Sojitra +3 more
2020Oncology Letters11 citations Open access
Semantic Scholar
TRPM3 gating in planar lipid bilayers defines peculiar agonist specificity
L. Demirkhanyan, Kunitoshi Uchida, M. Tominaga, E. Zakharian
2016Channels4 citations Open access
Semantic Scholar
Role of Polyphosphate in Cancer Cell Proliferation
L. Demirkhanyan, P. Elustondo, E. Pavlov, E. Zakharian
20144 citations Open access
Semantic Scholar
Role of TRPV1 Channels in Glioma Cell Viability and Survival
Yelena Nersesyan, S. Asuthkar, K. Velpula, Xiaohui Sun +2 more
20153 citations Open access
Semantic Scholar
Overweight-Related Hypertension in Middle-Aged Men Is Linked to Elevated Leptin, TNF-α, IL-6, Cholesterol, and Reduced Testosterone
Shalan Alaamri, A. Serafi, Zahir Hussain, Shouq K. Bafail +4 more
2025Pathophysiology2 citations Open access
Semantic Scholar
PHB Regulates Trafficking of TRPM8 to the Plasma Membrane
L. Demirkhanyan, D. Goa, E. Zakharian
2019Biophysical Journal2 citations Open access
Semantic Scholar
Crosstalk of Pain and Pleasure: TRPV1 is a Novel Oxytocin Receptor
Yelena Nersesyan, L. Demirkhanyan, Tyler Dawson, S. Asuthkar +3 more
20172 citations Open access
Semantic Scholar
Formation of Polyphosphate-Poly-Beta-Hydroxybutyrate Granule-Like Complexes in Heart Failure Myocytes
L. Demirkhanyan, Ian P. Palmer, W. Boyd, C. Sondergaard +6 more
20162 citations Open access
Semantic Scholar
IONOTROPIC EFFECT OF TESTOSTERONE ON TRPM8 The TRPM8 Protein Is a Testosterone Receptor: II. FUNCTIONAL EVIDENCE FOR AN
M. Wierman, K. Velpula, Baskaran Thyagarajan, E. Pavlov +7 more
20152 citations
Semantic Scholar
Abstract LB157: Electrochemical biosensor in the detection of pancreatic cancer biomarkers: AI driven model & patient cohort study
Rashwitha Julia Saldanha, Mareeswari Paramasivan, G. Munirathinam, Christopher Sumeet Gondi Gondi +2 more
2025Cancer Research1 citations
Semantic Scholar
Ketone Bodies and their Polymers in Heart Failure and Type 2 Diabetes: Lessons Learned from the Ketone Ester Diet
Phung N. Thai, L. Demirkhanyan, M. King, E. Zakharian +4 more
2019Biophysical Journal1 citations Open access
Semantic Scholar
TRPM8 Regulates Sexual Desire and Satiety
L. Demirkhanyan, V. Krishnan, S. Asuthkar, B. Alexander +7 more
20181 citations Open access
Semantic Scholar
TRPM8 is an Ionotropic Testosterone Receptor
S. Asuthkar, L. Demirkhanyan, Xiaohui Sun, P. Elustondo +6 more
20151 citations Open access
Semantic Scholar
Psychedelics and Autism Therapy: A Review of Current Research and Future Directions
Christopher S Gondi, Manu Gnanamony, Tarun P. Gondi, L. Nersesyan +1 more
2026Current Issues in Molecular Biology0 citations Open access
Semantic Scholar
AUTOMATED BREAST ULTRASOUND FOR DENSE BREASTS: RECENT FINDINGS (2020-2025)
Ameena Patel, Omar Babateen, Sulafa Ezzat Sharaf, Sumera Sohail +9 more
2025International Journal of Biology and Biotechnology0 citations Open access
Semantic Scholar
Serum Vitamin D Level Correlates Significantly With Leptin and Tumor Necrosis Factor-Alpha in Overweight Postmenopausal Women With Hypertension
Dina M. Qahwaji, A. Serafi, Shalan Alaamri, Zahir Hussain +5 more
2025Journal of Clinical Medicine Research0 citations
Semantic Scholar
Bridging in vitro Electrophysiology and in vivo Behavior in Zebrafish Models of Autism Spectrum Disorder
L. Demirkhanyan, M. Gnanamony, Christopher S Gondi
2025Journal of Innovative Solutions for Eco-Environmental Sustainability0 citations Open access
Semantic Scholar
Abstract A075: Spatial genomic expression profiling reveals differential marker expression patterns in mucinous cystic carcinoma of the pancreas with ductal involvement
Arshia Ghodrati, Chirag S. Gopinath, L. Demirkhanyan, M. Gnanamony +3 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 1137: Spatial expression profile of mucinous cystic neoplasm indicates a divergent malignant marker patterns in ductal and stromal regions
Arshia Ghodrati, Chirag S. Gopinath, A. Parvizi, M. Gnanamony +2 more
2024Cancer Research0 citations
Semantic Scholar
Abstract A076: Spatial genomic expression profiling reveals metastatic gene markers in mucinous cystic carcinoma of the pancreas and regional lymph nodes
Chirag S. Gopinath, Arshia Ghodrati, L. Demirkhanyan, M. Gnanamony +3 more
2024Cancer Research0 citations
Semantic Scholar
Clinical and molecular features of colloid carcinoma of the pancreas
L. A. Johnson, L. Demirkhanyan, J. Norton, C. Gondi +1 more
2023HPB0 citations
Semantic Scholar
Noncoding ribonucleic acid for pancreatic cancer therapy
L. Demirkhanyan, C. Gondi
2022Clinical Applications of Non-Coding RNAs in Cancer0 citations
Semantic Scholar
Structure-Function Relationship of the Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas Reinhardtii
L. McGoldrick, A. Singh, L. Demirkhanyan, David X. Gao +3 more
20200 citations Open access
Semantic Scholar
Oxytocin Modulates Nociception as a Direct Agonist of Pain-Sensing TRPV1
Yelena Nersesyan, L. Demirkhanyan, Deny Cabezas-Bratesco, Victoria Oakes +9 more
20180 citations Open access
Semantic Scholar
Assessment of Endogenous and Exogenous Modulators of the TRPM7 Channel in Planar Lipid Bilayers
L. Demirkhanyan, Tyler Dawson, T. Gudermann, V. Chubanov +1 more
20170 citations Open access
Semantic Scholar
Testosterone is a Highly Potent and Specific Agonist of TRPM8
Zahir Hussain, L. Demirkhanyan, S. Asuthkar, E. Zakharian
20160 citations Open access
Semantic Scholar
Ubiquitin-Mediated TRPM8 Protein Degradation in the Pathogenesis of Prostate Cancer
S. Asuthkar, Alejandro M. Cohen, L. Demirkhanyan, E. Zakharian
20160 citations Open access
Semantic Scholar
TRPM3 Exhibits Slight Temperature Sensitivity in the Planar Lipid Bilayer System and Requires the Presence of PIP2
L. Demirkhanyan, Kunitoshi Uchida, S. Asuthkar, Alejandro M. Cohen +2 more
20160 citations Open access
Semantic Scholar
Regulation of the TRPM3 Channel in Planar Lipid Bilayers
L. Demirkhanyan, Kunitoshi Uchida, E. Zakharian
20150 citations Open access
Semantic Scholar
Regulation of TRPM8 Channel Activity in Prostate Cancer by Androgens
S. Asuthkar, L. Demirkhanyan, Xiaohui Sun, P. Elustondo +3 more
20140 citations Open access
Semantic Scholar
Changes in PARP-1 activity in rat lver and thymocyte nuclei afterin vivo administration of cisplatin
I. Artsruni, K. Matinyan, L. Demirkhanyan, M. A. Melnikova-Sharova +3 more
20100 citations
Semantic Scholar
Lipids, Membrane Composition and Stability
J. S. Kang, W. Son, V. P. Ivanova, Z. V. Kovalyova +16 more
20030 citations Open access
Semantic Scholar
Hydrocortisone Induced Inhibition of Nuclease Activities in Rat Liver Nuclei
I. Artsruni, K. Matinyan, L. Demirkhanyan, E. Mndgoyan +1 more
20030 citations
Semantic Scholar
Estradiol Action on Phospholipid Composition of Rat Liver Chromatin
E. Gevorgyan, L. Demirkhanyan, I. Artsruni, ZhVYavroyan +2 more
20030 citations
Semantic Scholar

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P. Elustondo×7

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Alejandro M. Cohen×7

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Baskaran Thyagarajan×5

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Yelena Nersesyan×5

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Yelena Nersesyan — researcher profile on SciRah

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M. Gnanamony — researcher profile on SciRah