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A. Mazar · SciRah

Researcher profile · Semantic Scholar

A. Mazar

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A. Mazar — researcher profile on SciRah

h-index: 54
Works: 229
Citations: 8,371

Most-cited papers

Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.
Hilary A. Kenny, Chun-Yi Chiang, Erin A. White, Elizabeth M. Schryver +12 more
2014Journal of Clinical Investigation271 citations Open access
Semantic Scholar
Targeting SOD1 reduces experimental non–small-cell lung cancer.
Andrea Glasauer, Laura A. Sena, Lauren P. Diebold, A. Mazar +1 more
2014Journal of Clinical Investigation205 citations Open access
Semantic Scholar
Cancer-associated IDH1 promotes growth and resistance to targeted therapies in the absence of mutation
A. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley +18 more
2017Cell Reports186 citations Open access
Semantic Scholar
Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer
Amy L. Walz, A. Ugolkov, S. Chandra, A. Kozikowski +5 more
2017Clinical Cancer Research146 citations Open access
Semantic Scholar
Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.
R. Hashizume, Ali Zhang, S. Mueller, M. Prados +11 more
2016Neuro-Oncology116 citations Open access
Semantic Scholar
Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors
I. Calvo, Christopher R. Weber, Mohana Ray, Miguel A. Brown +16 more
2018Molecular Cancer Research108 citations Open access
Semantic Scholar
Patient-Derived Tumor Xenografts Are Susceptible to Formation of Human Lymphocytic Tumors
G. Bondarenko, A. Ugolkov, S. Rohan, P. Kulesza +6 more
2015Neoplasia99 citations Open access
Semantic Scholar
α5β1 Integrin Signaling Mediates Oxidized LDL-Induced Inflammation and Early Atherosclerosis
Arif Yurdagul, Jonette M. Green, Patrick Albert, M. C. McInnis +2 more
2014Arteriosclerosis, Thrombosis and Vascular Biology98 citations Open access
Semantic Scholar
The Apparent uPA/PAI-1 Paradox in Cancer: More than Meets the Eye
H. Kwaan, A. Mazar, B. McMahon
2013Seminars in Thrombosis and Hemostasis96 citations
Semantic Scholar
Biodistribution and in Vivo Toxicity of Aptamer-Loaded Gold Nanostars
D. H. M. Dam, Kayla S. B. Culver, I. Kandela, Raymond C. Lee +6 more
2014Nanomedicine: Nanotechnology, Biology and Medicine89 citations Open access
Semantic Scholar
Nano-Encapsulation of Arsenic Trioxide Enhances Efficacy against Murine Lymphoma Model while Minimizing Its Impact on Ovarian Reserve In Vitro and In Vivo
R. Ahn, S. Barrett, M. Raja, J. Jozefik +10 more
2013PLoS ONE77 citations Open access
Semantic Scholar
GSK-3 inhibition overcomes chemoresistance in human breast cancer
A. Ugolkov, I. Gaisina, Jin-San Zhang, D. Billadeau +8 more
2016Cancer Letters75 citations Open access
Semantic Scholar
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.
K. Frankowski, Chen Wang, S. Patnaik, F. Schoenen +44 more
2018Science Translational Medicine65 citations Open access
Semantic Scholar
Copper Chelator ATN-224 Induces Peroxynitrite-Dependent Cell Death in Hematological Malignancies
Kristy Lee, M. Briehl, A. Mazar, I. Batinic-Haberle +4 more
2013Free Radical Biology & Medicine59 citations Open access
Semantic Scholar
Macrogenomic engineering via modulation of the scaling of chromatin packing density
L. Almassalha, G. Bauer, Wenli Wu, L. Cherkezyan +14 more
2017Nature Biomedical Engineering55 citations Open access
Semantic Scholar
Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response
L. Ding, V. Madamsetty, Spencer Kiers, O. Alekhina +12 more
2019Clinical Cancer Research54 citations Open access
Semantic Scholar
uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery
M. C. Boonstra, P. V. van Driel, D. V. van Willigen, M. Stammes +11 more
2015OncoTarget54 citations Open access
Semantic Scholar
Melanoma cells block PEDF production in fibroblasts to induce the tumor-promoting phenotype of cancer-associated fibroblasts
Nkechiyere G. Nwani, M. L. Deguiz, B. Jiménez, E. Vinokour +4 more
2016Cancer Research49 citations Open access
Semantic Scholar
The Many Spaces of uPAR: Delivery of Theranostic Agents and Nanobins to Multiple Tumor Compartments through a Single Target
T. O'Halloran, R. Ahn, Patrick L. Hankins, E. Swindell +1 more
2013Theranostics47 citations Open access
Semantic Scholar
Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)
Xiangxi Xu, Yuan Cai, Ying Wei, F. Doñate +10 more
2014PLoS ONE46 citations Open access
Semantic Scholar
Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study
M. C. Boonstra, F. P. Verbeek, A. Mazar, H. A. Prevoo +4 more
2014BMC Cancer45 citations Open access
Semantic Scholar
9-ING-41, a small molecule inhibitor of GSK-3beta, potentiates the effects of anticancer therapeutics in bladder cancer
Hiroo Kuroki, Tsutomu Anraku, A. Kazama, V. Bilim +6 more
2019Scientific Reports44 citations Open access
Semantic Scholar
Arsenoplatin-1 is a Dual Pharmacophore Anti-Cancer Agent
Đenana Miodragović, A. Merlino, E. Swindell, Abraham Bogachkov +7 more
2019Journal of the American Chemical Society44 citations Open access
Semantic Scholar
Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
Ruifen Dong, W. Qiang, Haiyang Guo, Xiaofei Xu +4 more
2016Journal of Hematology & Oncology41 citations Open access
Semantic Scholar
Precision therapeutic targeting of human cancer cell motility
Li Xu, R. Gordon, Rebecca L. Farmer, A. Pattanayak +19 more
2018Nature Communications37 citations Open access
Semantic Scholar
Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC Dependent Cell Death in T-Cell and Hodgkin Lymphoma
Dashnamoorthy Ravi, A. Beheshti, N. Abermil, F. Passero +9 more
2016Cancer Research36 citations Open access
Semantic Scholar
Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models
A. Ugolkov, W. Qiang, G. Bondarenko, D. Procissi +8 more
2017Translational Oncology33 citations Open access
Semantic Scholar
Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
J. Bell, F. Eckerdt, Harshil Dhruv, D. Finlay +17 more
2017Molecular Cancer Research32 citations Open access
Semantic Scholar
Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity
Irina N. Gaisina, W. Tueckmantel, A. Ugolkov, S. Shen +6 more
2015ChemMedChem30 citations Open access
Semantic Scholar
Urokinase Plasminogen Activator System Targeted Delivery of Nanobins as a Novel Ovarian Cancer Therapeutics
Yi-Lin Zhang, Hilary A. Kenny, E. Swindell, A. Mitra +6 more
2013Molecular Cancer Therapeutics30 citations Open access
Semantic Scholar
9-ING-41, a small molecule Glycogen Synthase Kinase-3 inhibitor, is active in neuroblastoma
A. Ugolkov, G. Bondarenko, Oleksii Dubrovskyi, Ana P. Berbegall +6 more
2018Anti-Cancer Drugs29 citations Open access
Semantic Scholar
Randomized phase 2 trial of a novel clonidine mucoadhesive buccal tablet for the amelioration of oral mucositis in patients treated with concomitant chemo-radiotherapy for head and neck cancer.
J. Giralt, Y. Tao, R. Kortmann, X. Zasadny +13 more
2020International Journal of Radiation Oncology, Biology, Physics26 citations Open access
Semantic Scholar
Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells
S. de Geus, V. Baart, M. C. Boonstra, P. Kuppen +7 more
2017Biomarker Insights26 citations Open access
Semantic Scholar
Mesenchymal stromal cells enhance self-assembly of a HUVEC tubular network through uPA-uPAR/VEGFR2/integrin/NOTCH crosstalk.
I. Beloglazova, V. Stepanova, E. Zubkova, K. Dergilev +7 more
2021Biochimica et biophysica acta. Molecular cell research25 citations Open access
Semantic Scholar
uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions
Niaz Mahmood, A. Arakelian, H. Khan, I. Tanvir +2 more
2020Bone Research22 citations Open access
Semantic Scholar
Clinically relevant GSK-3β inhibitor 9-ING-41 is active as a single agent and in combination with other antitumor therapies in human renal cancer
Tsutomu Anraku, Hiroo Kuroki, A. Kazama, V. Bilim +6 more
2019International Journal of Molecular Medicine22 citations Open access
Semantic Scholar
The Novel Organic Arsenical Darinaparsin Induces MAPK-Mediated and SHP1-Dependent Cell Death in T-cell Lymphoma and Hodgkin’s Lymphoma Cells and Human Xenograft Models
Dashnamoorthy Ravi, Savita Bhalla, R. Gartenhaus, J. Crombie +4 more
2014Clinical Cancer Research22 citations Open access
Semantic Scholar
GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents
Reem Karmali, V. Chukkapalli, L. Gordon, J. Borgia +3 more
2017OncoTarget21 citations Open access
Semantic Scholar
The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma
Kristy Lee, Matthew R Hart, M. Briehl, A. Mazar +1 more
2014International Journal of Oncology21 citations Open access
Semantic Scholar
Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors
V. Baart, L. van Manen, S. Bhairosingh, F. Vuijk +10 more
2021Molecular Imaging and Biology19 citations Open access
Semantic Scholar
NT113, a pan-ERBB Inhibitor with High Brain Penetrance, Inhibits the Growth of Glioblastoma Xenografts with EGFR Amplification
Y. Yoshida, T. Ozawa, Tsun-Wen Yao, W. Shen +11 more
2014Molecular Cancer Therapeutics18 citations Open access
Semantic Scholar
A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma.
V. Baart, G. van der Horst, M. Deken, S. Bhairosingh +12 more
2021European Journal of Cancer16 citations Open access
Semantic Scholar
Targeting melanoma with front-line therapy does not abrogate Nodal-expressing tumor cells
M. Hendrix, I. Kandela, A. Mazar, E. Seftor +6 more
2017Laboratory Investigation15 citations Open access
Semantic Scholar
Virtual High-Throughput Screening To Identify Novel Activin Antagonists
Jie Zhu, R. Mishra, G. Schiltz, Yogeshwar Makanji +3 more
2015Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Aberrant expression of glycogen synthase kinase-3β in human breast and head and neck cancer
A. Ugolkov, M. Matsangou, T. Taxter, T. O'Halloran +3 more
2018Oncology Letters13 citations Open access
Semantic Scholar
PET in vivo generators 134Ce and 140Nd on an internalizing monoclonal antibody probe
G. Severin, J. Fonslet, L. Kristensen, C. H. Nielsen +5 more
2022Scientific Reports12 citations Open access
Semantic Scholar
Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging
Dongzhi Yang, G. Severin, C. Dougherty, R. Lombardi +6 more
2016OncoTarget12 citations Open access
Semantic Scholar
Whole-body imaging of cell death provides a systemic, minimally invasive, dynamic and near-real time indicator for chemotherapeutic drug toxicity
Steven E. Johnson, A. Ugolkov, C. Haney, G. Bondarenko +7 more
2018Clinical Cancer Research11 citations Open access
Semantic Scholar
6‐Methoxyethylamino‐numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib
Yan-Ning Liu, G. Lou, J. Norton, Chen Wang +11 more
2017The FASEB Journal11 citations Open access
Semantic Scholar
An ELISA method detecting the active form of suPAR.
Xiaolei Zhou, Mingming Xu, Hai-Long Huang, A. Mazar +3 more
2016Talanta: The International Journal of Pure and Applied Analytical Chemistry11 citations
Semantic Scholar

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