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D. Witonsky · SciRah

Researcher profile · Semantic Scholar

D. Witonsky

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D. Witonsky — researcher profile on SciRah

h-index: 24
Works: 52
Citations: 4,317

Most-cited papers

Reconstructing Native American Population History
D. Reich, N. Patterson, D. Campbell, A. Tandon +60 more
2012Nature793 citations Open access
Semantic Scholar
Using Environmental Correlations to Identify Loci Underlying Local Adaptation
G. Coop, D. Witonsky, A. Di Rienzo, J. Pritchard
2010Genetics707 citations Open access
Semantic Scholar
CYP3A variation and the evolution of salt-sensitivity variants.
E. Thompson, H. Kuttab-Boulos, D. Witonsky, L. Yang +2 more
2004American Journal of Human Genetics310 citations Open access
Semantic Scholar
Adaptations to Climate in Candidate Genes for Common Metabolic Disorders
A. Hancock, D. Witonsky, A. Gordon, G. Eshel +3 more
2008PLoS Genetics304 citations Open access
Semantic Scholar
Adaptations to Climate-Mediated Selective Pressures in Humans
A. Hancock, D. Witonsky, G. Alkorta-Aranburu, C. Beall +6 more
2011PLoS Genetics303 citations Open access
Semantic Scholar
Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency
A. Hancock, D. Witonsky, E. Ehler, G. Alkorta-Aranburu +7 more
2010Proceedings of the National Academy of Sciences of the United States of America209 citations Open access
Semantic Scholar
The Genetic Architecture of Adaptations to High Altitude in Ethiopia
G. Alkorta-Aranburu, C. Beall, D. Witonsky, A. Gebremedhin +2 more
2012PLoS Genetics204 citations Open access
Semantic Scholar
Admixture facilitates genetic adaptations to high altitude in Tibet
Choongwon Jeong, G. Alkorta-Aranburu, B. Basnyat, Maniraj Neupane +4 more
2014Nature Communications188 citations Open access
Semantic Scholar
Long-term genetic stability and a high-altitude East Asian origin for the peoples of the high valleys of the Himalayan arc
Choongwon Jeong, A. Ozga, D. Witonsky, H. Malmström +8 more
2016Proceedings of the National Academy of Sciences of the United States of America180 citations Open access
Semantic Scholar
The genetic prehistory of the Andean highlands 7000 years BP though European contact
J. Lindo, R. Haas, Courtney A. Hofman, Mario Apata +13 more
2018Science Advances145 citations Open access
Semantic Scholar
Adaptations to new environments in humans: the role of subtle allele frequency shifts
A. Hancock, G. Alkorta-Aranburu, D. Witonsky, A. Di Rienzo
2010Philosophical Transactions of the Royal Society B: Biological Sciences145 citations Open access
Semantic Scholar
Interactions between Glucocorticoid Treatment and Cis-Regulatory Polymorphisms Contribute to Cellular Response Phenotypes
J. Maranville, Francesca Luca, Allison L. Richards, X. Wen +4 more
2011PLoS Genetics106 citations Open access
Semantic Scholar
The classification of quadrilaterals : a study of definition
Z. Usiskin, Jennifer Griffin, D. Witonsky, Edwin Willmore
200875 citations
Semantic Scholar
Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors
Chi-Chun Liu, D. Witonsky, A. Gosling, J. Lee +9 more
2022Nature Communications74 citations Open access
Semantic Scholar
A reduced representation approach to population genetic analyses and applications to human evolution.
Francesca Luca, R. Hudson, D. Witonsky, A. Di Rienzo
2011Genome Research69 citations Open access
Semantic Scholar
Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal
Choongwon Jeong, D. Witonsky, B. Basnyat, Maniraj Neupane +5 more
2017bioRxiv65 citations Open access
Semantic Scholar
Adaptive Variation Regulates the Expression of the Human SGK1 Gene in Response to Stress
Francesca Luca, Sonal Kashyap, C. Southard, M. Zou +3 more
2009PLoS Genetics48 citations Open access
Semantic Scholar
Prevalence of common disease-associated variants in Asian Indians
T. Pemberton, Niyati U. Mehta, D. Witonsky, A. Di Rienzo +3 more
2008BMC Genetics47 citations Open access
Semantic Scholar
Comparative genomics analysis of human sequence variation in the UGT1A gene cluster
ML Maitland, C. Grimsley, H. Kuttab-Boulos, D. Witonsky +4 more
2006The Pharmacogenomics Journal39 citations Open access
Semantic Scholar
Allelic imbalance identifies novel tissue specific cis-regulatory variation for human UGT2B15
Chang Sun, C. Southard, D. Witonsky, O. Olopade +1 more
2010Human Mutation34 citations Open access
Semantic Scholar
A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk
Chang Sun, D. Huo, C. Southard, B. Nemesure +6 more
2011Human Genetics33 citations Open access
Semantic Scholar
Genetic mapping with multiple levels of phenotypic information reveals determinants of lymphocyte glucocorticoid sensitivity.
J. Maranville, Shaneen S Baxter, D. Witonsky, Meredith Chase +1 more
2013American Journal of Human Genetics27 citations Open access
Semantic Scholar
Genetic, Functional and Molecular Features of Glucocorticoid Receptor Binding
Francesca Luca, J. Maranville, Allison L. Richards, D. Witonsky +2 more
2013PLoS ONE27 citations Open access
Semantic Scholar
Natural selection and functional genetic variation in the p53 pathway.
Lara E. Sucheston, D. Witonsky, D. Hastings, O. Yildiz +3 more
2011Human Molecular Genetics26 citations Open access
Semantic Scholar
A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans
Olivia A. Gray, Jennifer Yoo, Débora R. Sobreira, Jordan Jousma +7 more
2022Science Advances24 citations Open access
Semantic Scholar
Allele-Specific Down-Regulation of RPTOR Expression Induced by Retinoids Contributes to Climate Adaptations
Chang Sun, C. Southard, D. Witonsky, R. Kittler +1 more
2010PLoS Genetics23 citations Open access
Semantic Scholar
Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells
Silvia N. Kariuki, J. Maranville, Shaneen S Baxter, Choongwon Jeong +5 more
2016PLoS ONE18 citations Open access
Semantic Scholar
Genomic and epigenomic active vitamin Dresponses in human colonic organoids.
Jin-Chao Li, D. Witonsky, Emily Sprague, Dereck Alleyne +3 more
2021Physiological Genomics16 citations Open access
Semantic Scholar
Colonic transcriptional response to 1α,25(OH)2 vitamin D3 in African- and European-Americans
Dereck Alleyne, D. Witonsky, Brandon L. Mapes, Shigeki Nakagome +5 more
2017Journal of Steroid Biochemistry and Molecular Biology16 citations Open access
Semantic Scholar
Higher oxygen content and transport characterize high-altitude ethnic Tibetan women with the highest lifetime reproductive success
Sheng-Hao Ye, Jia-Yang Sun, S. Craig, A. Di Rienzo +9 more
2024Proceedings of the National Academy of Sciences of the United States of America14 citations
Semantic Scholar
SNP discovery, expression and cis-regulatory variation in the UGT2B genes
Chang Sun, C. Southard, D. Huo, Ryan D. Hernandez +3 more
2011The Pharmacogenomics Journal12 citations Open access
Semantic Scholar
Transcriptomic analysis of iPSC-derived endothelium reveals adaptations to high altitude hypoxia in energy metabolism and inflammation
Olivia A. Gray, D. Witonsky, Jordan Jousma, Débora R. Sobreira +4 more
2025PLoS Genetics9 citations Open access
Semantic Scholar
Natural selection and functional genetic variation in the p 53 pathway
Lara E. Sucheston, D. Witonsky, D. Hastings, O. Yildiz +3 more
20117 citations
Semantic Scholar
Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes
Silvia N. Kariuki, J. Blischak, Shigeki Nakagome, D. Witonsky +1 more
2015G3: Genes, Genomes, Genetics6 citations Open access
Semantic Scholar
Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes
Jose A. Urban Aragon, Esha Bandyopadhyay, Amali S. Fernando, Constanza de la Fuente Castro +14 more
2025Current Biology5 citations Open access
Semantic Scholar
Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier
Esha Bandyopadhyay, D. Witonsky, Constanza de la Fuente Castro, N. Pasupuleti +28 more
2025Science Advances3 citations Open access
Semantic Scholar
Living in poverty is associated with gene expression changes in immune cells.
Nicole S Arnold, Justyna A. Resztak, D. Witonsky, Adnan Alazizi +6 more
2025Genetics3 citations
Semantic Scholar
Distinct positions of genetic and oral histories: Perspectives from India
Arjun Biddanda, Esha Bandyopadhyay, Constanza de la Fuente Castro, D. Witonsky +14 more
2024bioRxiv3 citations Open access
Semantic Scholar
Genomic and epigenomic responses to aspirin in human colonic organoids.
D. Witonsky, M. Bielski, Jin-Chao Li, Kristi M. Lawrence +3 more
2023Physiological Genomics1 citations Open access
Semantic Scholar
Genomic, physiological and social contributions to the survival of post-reproductive ethnically Tibetan women residing at high altitudes in Nepal
C. Beall, B. Basnyat, S. Craig, A. Di Rienzo +2 more
20201 citations
Semantic Scholar
Unelevated hemoglobin concentration and pulse associate with lifetime reproductive success of ethnic Tibetan women at high altitude in Nepal
Choongwon Jeong, D. Witonsky, B. Basnyat, Maniraj Neupane +5 more
20191 citations
Semantic Scholar
Sri Lankan maternal ancestry reveals early migrations from Africa along the Indian Ocean
Anjana Welikala, Shailesh Desai, Amali S. Fernando, Joanne T. Kotelawala +12 more
2026PLoS ONE0 citations Open access
Semantic Scholar
Ancient human genomes from Ladakh reveal Tibetan, South Asian, and Central Asian admixture over the last three millennia
N. Rai, Bhavna Ahlawat, A. Dwivedi, Snigdha Konar +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
Poverty shapes the transcriptome of immune cells
Nicole S Arnold, Justyna A. Resztak, D. Witonsky, Adnan Alazizi +6 more
2023bioRxiv0 citations Open access
Semantic Scholar
Peer Review #3 of "The effects of genetic drift and genomic selection on differentiation and local adaptation of the introduced populations of Aedes albopictus in southern Russia (v0.1)"
E. Konorov, V. Yurchenko, I. Patraman, Alexander Lukashev +395 more
20210 citations Open access
Semantic Scholar
Su1127 INTEGRATED MAPPING OF CHROMATIN ACCESSIBILITY AND TRANSCRIPTIONAL RESPONSES TO VITAMIN D IN HUMAN COLONIC ORGANOIDS
Jin-Chao Li, D. Witonsky, Emily Sprague, M. Bielski +2 more
20200 citations
Semantic Scholar
Tu1210 GENOME-WIDE TRANSCRIPTIONAL RESPONSES TO ASPIRIN WITH AND WITHOUT INFLAMMATORY STIMULANTS IN HUMAN COLONIC ORGANOIDS
Jin-Chao Li, D. Witonsky, Dereck Alleyne, Emily Sprague +3 more
20200 citations
Semantic Scholar
Selection for lifetime reproductive success among ethnic Tibetans residing at high altitude in Nepal
Choongwon Jeong, D. Witonsky, B. Basnyat, Maniraj Neupane +5 more
20190 citations
Semantic Scholar
Abstract B19: Colonic transcriptional response to 1,25(OH)2 vitamin D in African and European Americans
S. Kupfer, Brandon L. Mapes, Shigeki Nakagome, D. Witonsky +1 more
20160 citations
Semantic Scholar
Technical Report: Assessment of the genetic analyses of Rasmussen et al. (2015)
J. Novembre, D. Witonsky, A. Di Rienzo
20160 citations
Semantic Scholar

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G. Alkorta-Aranburu×6
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C. Southard — researcher profile on SciRah