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I. Aragon · SciRah

Researcher profile · Semantic Scholar

I. Aragon

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I. Aragon — researcher profile on SciRah

h-index: 16
Works: 39
Citations: 1,040

Most-cited papers

Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest.
Z. Zuo, G. Urban, J. Scammell, N. Dean +3 more
1999Biochemistry135 citations
Semantic Scholar
Ser/Thr Protein Phosphatase 5 Inactivates Hypoxia-induced Activation of an Apoptosis Signal-regulating Kinase 1/MKK-4/JNK Signaling Cascade*
Guo-Fei Zhou, Teresa A. Golden, I. Aragon, R. Honkanen
2004Journal of Biological Chemistry125 citations Open access
Semantic Scholar
MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response
Andrew E. Byrd, I. Aragon, J. Brewer
2012Journal of Cell Biology117 citations Open access
Semantic Scholar
The developmentally regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes.
Curtis L. Browning, D. E. Culberson, I. Aragon, R. Fillmore +3 more
1998Developmental Biology97 citations Open access
Semantic Scholar
Serine / threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling
D. Dean, G. Urban, I. Aragon, M. Swingle +5 more
2001BMC Cell Biology76 citations Open access
Semantic Scholar
Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer.
Teresa A. Golden, I. Aragon, Beth M. Rutland, J. Tucker +6 more
2008Biochimica et Biophysica Acta63 citations Open access
Semantic Scholar
The Specialized Unfolded Protein Response of B Lymphocytes: ATF6α-Independent Development of Antibody-Secreting B cells
I. Aragon, R. Barrington, S. Jackowski, K. Mori +1 more
2012Molecular Immunology56 citations Open access
Semantic Scholar
Identification of a Functional Link for the p53 Tumor Suppressor Protein in Dexamethasone-induced Growth Suppression*
G. Urban, Teresa A. Golden, I. Aragon, L. Cowsert +3 more
2003Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Identification of an Estrogen-inducible Phosphatase (PP5) That Converts MCF-7 Human Breast Carcinoma Cells into an Estrogen-independent Phenotype when Expressed Constitutively*
G. Urban, Teresa A. Golden, I. Aragon, J. Scammell +2 more
2001Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2Aα
Kathy Bonness, I. Aragon, Beth M. Rutland, S. Ofori-Acquah +2 more
2006Molecular Cancer Therapeutics48 citations Open access
Semantic Scholar
Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice.
Teresa A. Golden, I. Aragon, Guo-Fei Zhou, S. Cooper +2 more
2004Cancer Letters40 citations
Semantic Scholar
PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice
W. McDonough, I. Aragon, Justin Rich, James M. Murphy +4 more
2020The FASEB Journal34 citations Open access
Semantic Scholar
The β subunit of human rod photoreceptor cGMP‐gated cation channel is generated from a complex transcription unit
Michelle D. Ardell, I. Aragon, L. Oliveira, G.Erick Porche +2 more
1996FEBS Letters30 citations Open access
Semantic Scholar
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer
Rebecca M. Borneman, E. Gavin, A. Musiyenko, Wito Richter +13 more
2022Journal of Ovarian Research17 citations Open access
Semantic Scholar
Phosphatidylcholine as a metabolic cue for determining B cell fate and function
J. Brewer, V. Solodushko, I. Aragon, R. Barrington
2016Cellular Immunology16 citations Open access
Semantic Scholar
MicroRNA-30 c-2 * limits expression of proadaptive factor XBP 1 in the unfolded protein response
Andrew E. Byrd, I. Aragon, J. Brewer
201216 citations
Semantic Scholar
Inhibition of Type 4 cAMP-phosphodiesterases (PDE4s) in mice induces hypothermia via effects on behavioral and central autonomous thermoregulation
W. McDonough, Justin Rich, I. Aragon, L. A. Saleh +4 more
2020Biochemical Pharmacology15 citations Open access
Semantic Scholar
The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice.
A. Boyd, I. Aragon, Lina Abou Saleh, D. Southers +1 more
2021Biochemical Journal12 citations Open access
Semantic Scholar
Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice
A. Boyd, I. Aragon, Justin Rich, W. McDonough +5 more
2021Biology9 citations Open access
Semantic Scholar
Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia
L. A. Saleh, A. Boyd, I. Aragon, A. Koloteva +4 more
2021The FASEB Journal8 citations Open access
Semantic Scholar
Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice
I. Aragon, A. Boyd, Lina Abou Saleh, Justin Rich +3 more
2021Biochemical Pharmacology6 citations Open access
Semantic Scholar
Acute PDE4 Inhibition Induces a Transient Increase in Blood Glucose in Mice
Daniel Irelan, A. Boyd, E. Fiedler, Peter Lochmaier +5 more
2023International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Pharmacologic or Genetic PDE4 Inactivation Reduces Obesity and Improves Glucose Handling in Mice
Daniel Irelan, A. Boyd, I. Aragon, E. Fiedler +1 more
2022The FASEB Journal2 citations
Semantic Scholar
Abstract 1213: PDE10A as a novel target to suppress Wnt/β-catenin signaling and other oncogenic pathways in ovarian cancer
Rebecca Barber, E. Gavin, A. Musiyenko, Wito Richter +12 more
2021Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Ablation of PDE4B Protects from Lung Injury in a Mouse Model of Acute P. aeruginosa Infection
L. A. Saleh, I. Aragon, A. Boyd, W. McDonough +5 more
2020D35. LUNG INJURY AND REPAIR: CELLULAR MECHANISMS1 citations
Semantic Scholar
Abstract B31: Tumor-intrinsic B7-H3 regulates drug resistance, metabolism, and pathogenesis in ovarian cancer
Holly T. Taylor, J. Slamecka, A. Musiyenko, E. Gavin +7 more
2018Immunotherapy1 citations
Semantic Scholar
Abstract 5174: Phosphodiesterase 10A inhibition as a novel approach to suppress β-catenin signaling in ovarian cancer cells
L. M. da Silva, E. Gavin, Kevin Lee, Veronica Ramirez-Alcantara +8 more
20171 citations
Semantic Scholar
Abstract A76: Targeting phosphodiesterase 10A for chemoprevention and treatment of ovarian cancer.
L. M. da Silva, E. Gavin, Kevin Lee, I. Aragon +4 more
20161 citations
Semantic Scholar
Serum pregnancy‐associated plasma protein‐A levels in a cohort with cardiovascular disease (1158.2)
W. Gerthoffer, A. Hellmich, I. Aragon, C. Massey
20141 citations
Semantic Scholar
418 Ablation of two distinct phosphodiesterase subtypes produces diametrical (diametrically opposite) effects in an acute model of Pseudomonas aeruginosa–induced lung injury in mice
A. Boyd, L. A. Saleh, I. Aragon, E. Fiedler +5 more
2022Journal of Cystic Fibrosis0 citations Open access
Semantic Scholar
Ablation of PDE4A Exacerbates Pseudomonas aeruginosa‐Induced Acute Lung Injury in Mice
A. Boyd, Lina Abou Saleh, I. Aragon, E. Fiedler +5 more
2022The FASEB Journal0 citations
Semantic Scholar
Inhibition of PDE4 Potentiates the Anesthetic Effects of Isoflurane in Mice
I. Aragon, A. Boyd, Lina Abou Saleh, Justin Rich +3 more
2021The FASEB Journal0 citations Open access
Semantic Scholar
Inhibition of cAMP‐Phosphodiesterase 4 (PDE4) Induces Salivation in Mice
A. Boyd, I. Aragon, Lina Abou Saleh, Wito Richter
2021The FASEB Journal0 citations
Semantic Scholar
Inhibition of PDE4 Induces Hypothermia in Mice
W. McDonough, I. Aragon, Justin Rich, L. A. Saleh +4 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Nonselective Inhibition of PDE4 Induces Gastroparesis in Mice
W. McDonough, I. Aragon, Justin Rich, James M. Murphy +4 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Biomarkers to evaluate distress in cancer patients.
Elise Labbe-Coldsmith, T. W. Butler, P. Naylor, I. Aragon
20170 citations
Semantic Scholar
Phospholipid biosynthesis and antigen-specific B cell fate and function (LYM7P.621)
R. Barrington, V. Solodushko, I. Aragon, J. Brewer
2015Journal of Immunology0 citations
Semantic Scholar
Phosphatidylcholine as a metabolic cue for determining B cell fate and function (LYM6P.774)
Robert A. Barrington, V. Solodushko, I. Aragon, Joseph W. Brewer
2014Journal of Immunology0 citations
Semantic Scholar
In the Eye of the Cytostorm: Phosphodiesterase 4B (PDE4B) Ablation Alleviates Inflammation and Hypothermia in P. Aeruginosa Lung Infection
L. A. Saleh, A. Boyd, I. Aragon, D. Souterhs +7 more
TP4. TP004 ARDS, SEPSIS, AND TRANSPLANTATION MECHANISTIC STUDIES0 citations Open access
Semantic Scholar

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